Double stable isotope ultra performance liquid chromatographic-tandem mass spectrometric quantification of tissue content and activity of phenylethanolamine N-methyltransferase, the crucial enzyme responsible for synthesis of epinephrine

Analytical and Bioanalytical Chemistry

Volumn 405, Issue 5, 2013, Pages 1713-1719

  Qin, Nan ^a   Peitzsch, Mirko ^a   Menschikowski, Mario ^a   Siegert, Gabriele ^a   Pacak, Karel ^b   Eisenhofer, Graeme ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Pheochromocytoma; PNMT; UPLC MS MS

Indexed keywords

AMINO ACIDS; CALIBRATION; DEUTERIUM; ENZYME ACTIVITY; GENE EXPRESSION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NOREPINEPHRINE; TISSUE;

INTER-ASSAY COEFFICIENTS; LOWER LIMIT OF QUANTIFICATIONS; PHEOCHROMOCYTOMA; PNMT; S ADENOSYL L METHIONINES; TANDEM MASS SPECTROMETRIC; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

DRUG PRODUCTS;

EID: 84873743645     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-6599-x     Document Type: Article

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