Comparing the cost-effectiveness of two brain metastasis treatment modalities from a payer's perspective: Stereotactic radiosurgery versus surgical resection

Clinical Neurology and Neurosurgery

Volumn 115, Issue 3, 2013, Pages 276-284

  Vuong, Duong Anh ^a,b   Rades, Dirk ^c   Van Eck, Albertus T C ^d   Horstmann, Gerhard A ^d   Busse, Reinhard ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b Ministry of Health of Vietnam   (Viet Nam)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d Gamma Knife Centre Krefeld   (Germany)

Author keywords

Brain tumors; Economics; Stereotactic radiosurgery; Surgical resection

Indexed keywords

ADULT; ARTICLE; BRAIN METASTASIS; BRAIN TUMOR; CANCER CONTROL; CANCER SURGERY; CANCER THERAPY; COMPARATIVE STUDY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; FEMALE; FOLLOW UP; HEALTH CARE COST; HEALTH INSURANCE; HUMAN; MAJOR CLINICAL STUDY; MALE; METASTASIS RESECTION; PROPENSITY SCORE; QUALITY OF LIFE; REOPERATION; REPEAT PROCEDURE; RETROSPECTIVE STUDY; STEREOTACTIC RADIOSURGERY; SURVIVAL RATE; SURVIVAL TIME; TUMOR RECURRENCE;

AGED; ALGORITHMS; ANESTHESIA, GENERAL; BRAIN NEOPLASMS; COHORT STUDIES; COST-BENEFIT ANALYSIS; COSTS AND COST ANALYSIS; DATABASES, FACTUAL; FEMALE; GERMANY; HUMANS; KAPLAN-MEIER ESTIMATE; LIFE EXPECTANCY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NATIONAL HEALTH PROGRAMS; NEUROSURGICAL PROCEDURES; PROSPECTIVE STUDIES; RADIOSURGERY; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84873732342     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2012.05.005     Document Type: Article

References (58)

1. Cancer in Germany 2003-2004. Incidence and Trends 6th ed. 2008 Robert Koch Institute/Association of Population-Based Cancer Registries in Germany Berlin
2. Z. Petrovich, C. Yu, S.L. Giannotta, S. O'Day, and M.L.J. Apuzzo Survival and pattern of failure in brain metastasis treated with stereotactic gamma knife radiosurgery Journal of Neurosurgery 12 Suppl. 5 2002 499 506 (Pubitemid 35424334)
3. A.F. Eichler, and J.S. Loeffler Multidisciplinary management of brain metastases The Oncologist 12 7 2007 884 898 (Pubitemid 47328231)
4. D. Kondziolka, J.J. Martin, J.C. Flickinger, D.M. Friedland, A.M. Brufsky, and J. Baar Long-term survivors after gamma knife radiosurgery for brain metastases Cancer 104 12 2005 2784 2791 (Pubitemid 41798289)
5. B.P. O'Neill, N.J. Iturria, M.J. Link, B.E. Pollock, K.V. Ballman, and J.R. O'Fallon A comparison of surgical resection and stereotactic radiosurgery in the treatment of solitary brain metastases International Journal of Radiation Oncology, Biology, Physics 55 5 2003 1169 1176 (Pubitemid 36338280)
6. S.M. Arnold, and R.A. Patchell Diagnosis and management of brain metastases Hematology/Oncology Clinics of North America 15 6 2001 1085 1107 vii (Pubitemid 33131200)
7. R. Busse, and A. Riesberg Health care systems in transition: Germany 2004 WHO Regional Office for Europe on Behalf of the European Observatory on Health System and Policies Copenhagen
8. M.F. Drummond, and A.R. Mason European perspective on the costs and cost-effectiveness of cancer therapies Journal of Clinical Oncology 25 2 2007 191 195 (Pubitemid 350003033)
9. M. Mehta, W. Noyes, B. Craig, J. Lamond, R. Auchter, and M. French A cost-effectiveness and cost-utility analysis of radiosurgery vs. resection for single-brain metastases International Journal of Radiation Oncology, Biology, Physics 39 2 1997 445 454
10. D.Y. Cho, M. Tsao, W.Y. Lee, and C.S. Chang Socioeconomic costs of open surgery and gamma knife radiosurgery for benign cranial base tumors Neurosurgery 58 5 2006 866 873
11. M.J. Rutigliano, L.D. Lunsford, D. Kondziolka, M.J. Strauss, V. Khanna, and M. Green The cost effectiveness of stereotactic radiosurgery versus surgical resection in the treatment of solitary metastatic brain tumors Neurosurgery 37 3 1995 445 453
12. G. Wellis, R. Nagel, C. Vollmar, and H.J. Steiger Direct costs of microsurgical management of radiosurgically amenable intracranial pathology in Germany: an analysis of meningiomas, acoustic neuromas, metastases and arteriovenous malformations of less than 3 cm in diameter Acta Neurochirurgica 145 4 2003 249 255 (Pubitemid 36560921)
13. F.M. Riemenschneuder, C. Schwarzbach, A. Bockelbrink, I. Ernst, and C. Vauth Medizinische und gesundheitsoekonomische Bewerting der radiochirurgie zur behandlung von hirnmetastasen DIMDI 2009 2009 HTA-Bericht 84
14. T. Mindermann Tumor recurrence and survival following gamma knife surgery for brain metastases Journal of Neurosurgery 102 Suppl. 2005 287 288 (Pubitemid 44783971)
15. N. Chernyak, F. Petrak, K. Plack, M. Hautzinger, M.J. Müller, and G. Giani Cost-effectiveness analysis of cognitive behaviour therapy for treatment of minor or mild-major depression in elderly patients with type 2 diabetes: study protocol for the economic evaluation alongside the MIND-DIA randomized controlled trial (MIND-DIA CEA) BMC Geriatrics 9 25 2009
16. UKM: DRG Research Group-Webgrouper. In: DRG Research Group Medizinisches Management. Available from: http://drg.uni-muenster.de/index.php?option=com- webgrouper&view=webgrouper&Itemid=26.
17. D.S. Kreinsen, A. Geissler, and R. Busse The ABC of DRGs Euro Observer 11 4 2009
18. T.B. Johannesen, J. Norum, K. Lote, D. Scheie, and H. Hirschberg A cost-minimising analysis of standard radiotherapy and two experimental therapies in glioblastoma Radiotherapy and Oncology 62 2 2002 227 231 (Pubitemid 34286456)
19. A.R. Willan, and A. Briggs Statistical analysis of cost-effectiveness data 2006 John Willey & Sons Ltd. England (West Sussex)
20. D.F. Heitjan, C.Y. Kim, and H. Li Bayesian estimation of cost-effectiveness from censored data Statistics in Medicine 23 8 2004 1297 1309 (Pubitemid 38514825)
21. D.Y. Lin, E.J. Feuer, R. Etzioni, and Y. Wax Estimating medical costs from incomplete follow-up data Biometrics 53 2 1997 419 434 (Pubitemid 27262208)
22. M.A. Hlatky Economic endpoints in clinical trials Epidemiologic Reviews 24 1 2002 80 84 (Pubitemid 34742959)
23. D. Rubin The use of matched sampling and regression adjustment to remove bias in observational studies Biometrics 29 1973 185 203
24. P.C. Austin A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003 Statistics in Medicine 27 12 2008 2037 2049 (Pubitemid 351772300)
25. R.B. D'Agostino Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group Statistics in Medicine 17 19 1998 2265 2281
26. E.L. Kaplan, and P. Meier Nonparametric estimate from incomplete observations Journal of the American Statistical Association 53 1958 457 481
27. D.R. Cox Regression models and life tables Journal of the Royal Statistical Society 34 1972 187 220
28. D.G. Kim, H.T. Chung, H.S. Gwak, S.H. Paek, H.W. Jung, and D.H. Han Gamma knife radiosurgery for brain metastases: prognostic factors for survival and local control Journal of Neurosurgery 93 Suppl. 3 2000 23 29 (Pubitemid 32799540)
29. F.J. Lagerwaard, P.C. Levendag, P.J. Nowak, W.M. Eijkenboom, P.E. Hanssens, and P.I. Schmitz Identification of prognostic factors in patients with brain metastases: a review of 1292 patients International Journal of Radiation Oncology, Biology, Physics 43 4 1999 795 803 (Pubitemid 29152652)
30. D. Rades, G. Bohlen, A. Pluemer, T. Veninga, P. Hanssens, and J. Dunst Stereotactic radiosurgery alone versus resection plus whole-brain radiotherapy for 1 or 2 brain metastases in recursive partitioning analysis class 1 and 2 patients Cancer 109 12 2007 2515 2521 (Pubitemid 46906471)
31. H. Aoyama, H. Shirato, M. Tago, K. Nakagawa, T. Toyoda, and K. Hatano Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial Journal of the American Medical Association 295 21 2006 2483 2491 (Pubitemid 43854963)
32. J. Cohen Statistical power analysis for the behavioral sciences rev. ed. 1997 Academic Press New York
33. N. Neymark, I. Adriaenssen, T. Gorlia, S. Caleo, and M. Bolla Estimating survival gain for economic evaluations with survival time as principal endpoint: a cost-effectiveness analysis of adding early hormonal therapy to radiotherapy in patients with locally advanced prostate cancer Health Economics 11 3 2002 233 248 (Pubitemid 34284848)
34. A. Ash, and M. Shwartz R2: a useful measure of model performance when predicting a dichotomous outcome Statistics in Medicine 18 4 1999 375 384 (Pubitemid 29057366)
35. M.A. Hlatky, D.B. Boothroyd, and I.M. Johnstone Economic evaluation in long-term clinical trials Statistics in Medicine 21 19 2002 2879 2888
36. P.W. Sperduto, and W.A. Hall The cost-effectiveness for alternate treatments for single brain metastases D. Kondziolka, Radiosurgery 1995 1996 Karger Basel 180 187
37. R.A. Patchell, P.A. Tibbs, J.W. Walsh, R.J. Dempsey, Y. Maruyama, and R.J. Kryscio A randomized trial of surgery in the treatment of single metastases to the brain The New England Journal of Medicine 322 8 1990 494 500 (Pubitemid 20067825)
38. R.M. Auchter, J.P. Lamond, E. Alexander, J.M. Buatti, R. Chappell, and W.A. Friedman A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis International Journal of Radiation Oncology, Biology, Physics 35 1 1996 27 35 (Pubitemid 26137165)
39. M. Wroński, and E. Arbit Resection of brain metastases from colorectal carcinoma in 73 patients Cancer 85 8 1999 1677 1685 (Pubitemid 29169667)
40. R.K. Bindal, R. Sawaya, M.E. Leavens, and J.J. Lee Surgical treatment of multiple brain metastases Journal of Neurosurgery 79 2 1993 210 216 (Pubitemid 23215837)
41. M. Wroński, E. Arbit, M. Burt, and J.H. Galicich Survival after surgical treatment of brain metastases from lung cancer: a follow-up study of 231 patients treated between 1976 and 1991 Journal of Neurosurgery 83 4 1995 605 616
42. G. Schackert Resection of brain metastases Acta Chirurgica 1996 18 23 Heft 1 (Pubitemid 26100590)
43. P.L. Penar, and J.T. Wilson Cost and survival analysis of metastatic cerebral tumors treated by resection and radiation Neurosurgery 34 5 1994 888 893
44. C.F. Huang, D. Kondziolka, J.C. Flickinger, and L.D. Lunsford Stereotactic radiosurgery for brainstem metastases Journal of Neurosurgery 91 4 1999 563 568 (Pubitemid 30133451)
45. B.J. Williams, D. Suki, B.D. Fox, C.E. Pelloski, M.V.C. Maldaun, and R.E. Sawaya Stereotactic radiosurgery for metastatic brain tumors: a comprehensive review of complications Journal of Neurosurgery 111 3 2009 439 448
46. D. Kondziolka, A. Patel, L.D. Lunsford, A. Kassam, and J.C. Flickinger Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases International Journal of Radiation Oncology, Biology, Physics 45 2 1999 427 434 (Pubitemid 29408559)
47. J.C. Chen, Z. Petrovich, S. O'Day, D. Morton, R. Essner, and S.L. Giannotta Stereotactic radiosurgery in the treatment of metastatic disease to the brain Neurosurgery 47 2 2000 268 279
48. J.C. Flickinger, L.D. Lunsford, S. Somaza, and D. Kondziolka Radiosurgery: its role in brain metastasis management Neurosurgery Clinics of North America 7 3 1996 497 504 (Pubitemid 26246632)
49. H.C. Pan, J. Sheehan, M. Stroila, M. Steiner, and L. Steiner Gamma knife surgery for brain metastases from lung cancer Journal of Neurosurgery 102 Suppl. 2005 128 133 (Pubitemid 44783939)
50. Y.S. Kim, D. Kondziolka, J.C. Flickinger, and L.D. Lunsford Stereotactic radiosurgery for patients with nonsmall cell lung carcinoma metastatic to the brain Cancer 80 11 1997 2075 2083 (Pubitemid 27506020)
51. A. Muacevic, B. Wowra, A. Siefert, J.C. Tonn, H.J. Steiger, and F.W. Kreth Microsurgery plus whole brain irradiation versus Gamma Knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial Journal of Neurooncology 87 3 2008 299 307
52. A. Muacevic, F.W. Kreth, G.A. Horstmann, R. Schmid-Elsaesser, B. Wowra, and H.J. Steiger Surgery and radiotherapy compared with gamma knife radiosurgery in the treatment of solitary cerebral metastases of small diameter Journal of Neurosurgery 91 1 1999 35 43
53. S. Matsunaga, T. Shuto, N. Kawahara, J. Suenaga, S. Inomori, and H. Fujino Gamma Knife surgery for metastatic brain tumors from primary breast cancer: treatment indication based on number of tumors and breast cancer phenotype Journal of Neurosurgery 113 Suppl. 2010 65 72
54. D. Kondziolka, L.D. Lunsford, and J.C. Flickinger The radiobiology of radiosurgery Neurosurgery Clinics of North America 10 2 1999 157 166 (Pubitemid 29210642)
55. S.D. Chang, and J.R. Adler Current treatment of patients with multiple brain metastases Neurosurgical Focus 9 2 2000 e5
56. M. Kretowska The influence of censoring for the performance of survival tree ensemble ICAISC 2010, part II, LNAI 6114 2010 524 531
57. QCP: Does your data violate Kaplan-Meier assumptions? Available from: http://www.quality-control-plan.com/StatGuide/kaplan-ass-viol.htm. [accessed December 2010].
58. D.M. Reineke, E.A. Pohl, and W.P. Murdock Survival analysis and maintenance policies for a series system, with highly censored data Reliability and Maintainability Symposium 1998 19-22, January 1998 182 188