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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1310-1314

Synthesis and biological evaluation of nucleoside analogues than contain silatrane on the basis of the structure of acyclovir (ACV) as novel inhibitors of hepatitis B virus (HBV)

(8) Han, Anyue a Li, Lingna a Qing, Kuiyou a Qi, Xiaolu a Hou, Leping a Luo, Xintong a Shi, Shaohua a Ye, Faqing a

a WENZHOU MEDICAL UNIVERSITY (China)

Author keywords

ACV; HBV transgenic mouse; Hepatitis B virus; HepG2.2.15 cell; Silatrane

Indexed keywords

ACICLOVIR; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; INTERLEUKIN 2; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; SILATRANE DERIVATIVE; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG DESIGN; DRUG STRUCTURE; EVALUATION; FEMALE; FLOW CYTOMETRY; GENE TARGETING; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IC 50; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; T LYMPHOCYTE; TRANSGENIC MOUSE;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; FEMALE; HEP G2 CELLS; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGANOSILICON COMPOUNDS; PURINE NUCLEOSIDES; RANDOM ALLOCATION;

HEPATITIS B VIRUS; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 84873728191 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.12.097 Document Type: Article

Times cited : (32)

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