메뉴 건너뛰기




Volumn 5, Issue 2, 2013, Pages 663-677

Predicted peptides from non-structural proteins of porcine reproductive and respiratory syndrome virus are able to induce IFN-γ and IL-10

Author keywords

Epitopes; IL 10; Interferon gamma; Non structural proteins; PRRSV

Indexed keywords

EPITOPE; GAMMA INTERFERON; INTERLEUKIN 10; LEUKOCYTE ANTIGEN; MICROORGANISM PROTEIN; NONSTRUCTURAL PROTEIN 10; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5; NONSTRUCTURAL PROTEIN 9; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 84873724515     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v5020663     Document Type: Article
Times cited : (38)

References (31)
  • 2
    • 0030634897 scopus 로고    scopus 로고
    • Nidovirales: A new order comprising Coronaviridae and Arteriviridae
    • Cavanagh, D. Nidovirales: A new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 1997, 142, 629-633.
    • (1997) Arch. Virol , vol.142 , pp. 629-633
    • Cavanagh, D.1
  • 4
    • 0033008414 scopus 로고    scopus 로고
    • North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions
    • Allende, R.; Lewis, T.L.; Lu, Z.; Rock, D.L.; Kutish, G.F.; Ali, A.; Doster, A.R.; Osorio, F.A. North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regions. J. Gen. Virol. 1999, 80, 307-315.
    • (1999) J. Gen. Virol , vol.80 , pp. 307-315
    • Allende, R.1    Lewis, T.L.2    Lu, Z.3    Rock, D.L.4    Kutish, G.F.5    Ali, A.6    Doster, A.R.7    Osorio, F.A.8
  • 5
    • 0032982143 scopus 로고    scopus 로고
    • Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and is essential for virus replication
    • van Dinten, L.C.; Rensen, S.; Gorbalenya, A.E.; Snijder, E.J. Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and is essential for virus replication. J. Virol. 1999, 73, 2027-2037.
    • (1999) J. Virol , vol.73 , pp. 2027-2037
    • van Dinten, L.C.1    Rensen, S.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 6
    • 0035104619 scopus 로고    scopus 로고
    • Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: The nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes
    • Oleksiewicz, M.B.; Botner, A.; Toft, P.; Normann, P.; Storgaard, T. Epitope mapping porcine reproductive and respiratory syndrome virus by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes. J. Virol. 2001, 75, 3277-3290.
    • (2001) J. Virol , vol.75 , pp. 3277-3290
    • Oleksiewicz, M.B.1    Botner, A.2    Toft, P.3    Normann, P.4    Storgaard, T.5
  • 7
    • 34047123178 scopus 로고    scopus 로고
    • Cross-reactive antibody responses to nsp1 and nsp2 of Porcine reproductive and respiratory syndrome virus
    • Johnson, C.R.; Yu, W.; Murtaugh, M.P. Cross-reactive antibody responses to nsp1 and nsp2 of Porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 2007, 88, 1184-1195.
    • (2007) J. Gen. Virol , vol.88 , pp. 1184-1195
    • Johnson, C.R.1    Yu, W.2    Murtaugh, M.P.3
  • 8
    • 33748684385 scopus 로고    scopus 로고
    • Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus
    • de Lima, M.; Pattnaik, A.K.; Flores, E.F.; Osorio, F.A. Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus. Virology 2006, 353, 410-421.
    • (2006) Virology , vol.353 , pp. 410-421
    • de Lima, M.1    Pattnaik, A.K.2    Flores, E.F.3    Osorio, F.A.4
  • 9
    • 73949087536 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation
    • Beura, L.K.; Sarkar, S.N.; Kwon, B.; Subramaniam, S.; Jones, C.; Pattnaik, A.K.; Osorio, F.A. Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation. J. Virol. 2010, 84, 1574-1584.
    • (2010) J. Virol , vol.84 , pp. 1574-1584
    • Beura, L.K.1    Sarkar, S.N.2    Kwon, B.3    Subramaniam, S.4    Jones, C.5    Pattnaik, A.K.6    Osorio, F.A.7
  • 10
    • 77949499693 scopus 로고    scopus 로고
    • Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response
    • Chen, Z.; Zhou, X.; Lunney, J.K.; Lawson, S.; Sun, Z.; Brown, E.; Christopher-Hennings, J.; Knudsen, D.; Nelson, E.; Fang, Y. Immunodominant epitopes in nsp2 of porcine reproductive and respiratory syndrome virus are dispensable for replication, but play an important role in modulation of the host immune response. J. Gen. Virol. 2010, 91, 1047-1057.
    • (2010) J. Gen. Virol , vol.91 , pp. 1047-1057
    • Chen, Z.1    Zhou, X.2    Lunney, J.K.3    Lawson, S.4    Sun, Z.5    Brown, E.6    Christopher-Hennings, J.7    Knudsen, D.8    Nelson, E.9    Fang, Y.10
  • 11
    • 0037316360 scopus 로고    scopus 로고
    • Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virus
    • Suradhat, S.; Thanawongnuwech, R.; Poovorawan, Y. Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 2003, 84, 453-459.
    • (2003) J. Gen. Virol , vol.84 , pp. 453-459
    • Suradhat, S.1    Thanawongnuwech, R.2    Poovorawan, Y.3
  • 12
    • 47049098221 scopus 로고    scopus 로고
    • Porcine reproductive and respiratory syndrome virus infects mature porcine dendritic cells and up-regulates interleukin-10 production
    • Flores-Mendoza, L.; Silva-Campa, E.; Resendiz, M.; Osorio, F.A.; Hernandez, J. Porcine reproductive and respiratory syndrome virus infects mature porcine dendritic cells and up-regulates interleukin-10 production. Clin. Vaccine Immunol. 2008, 15, 720-725.
    • (2008) Clin. Vaccine Immunol , vol.15 , pp. 720-725
    • Flores-Mendoza, L.1    Silva-Campa, E.2    Resendiz, M.3    Osorio, F.A.4    Hernandez, J.5
  • 13
    • 21444433341 scopus 로고    scopus 로고
    • Immune responses of pigs after experimental infection with a European strain of Porcine reproductive and respiratory syndrome virus
    • Diaz, I.; Darwich, L.; Pappaterra, G.; Pujols, J.; Mateu, E. Immune responses of pigs after experimental infection with a European strain of Porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 2005, 86, 1943-1951.
    • (2005) J. Gen. Virol , vol.86 , pp. 1943-1951
    • Diaz, I.1    Darwich, L.2    Pappaterra, G.3    Pujols, J.4    Mateu, E.5
  • 14
    • 0036223761 scopus 로고    scopus 로고
    • Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain
    • Ostrowski, M.; Galeota, J.A.; Jar, A.M.; Platt, K.B.; Osorio, F.A.; Lopez, O.J. Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain. J. Virol. 2002, 76, 4241-4250.
    • (2002) J. Virol , vol.76 , pp. 4241-4250
    • Ostrowski, M.1    Galeota, J.A.2    Jar, A.M.3    Platt, K.B.4    Osorio, F.A.5    Lopez, O.J.6
  • 16
    • 77955855300 scopus 로고    scopus 로고
    • A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains
    • Vanhee, M.; Costers, S.; van Breedam, W.; Geldhof, M.F.; van Doorsselaere, J.; Nauwynck, H.J. A variable region in GP4 of European-type porcine reproductive and respiratory syndrome virus induces neutralizing antibodies against homologous but not heterologous virus strains. Viral. Immunol. 2010, 23, 403-413.
    • (2010) Viral. Immunol , vol.23 , pp. 403-413
    • Vanhee, M.1    Costers, S.2    van Breedam, W.3    Geldhof, M.F.4    van Doorsselaere, J.5    Nauwynck, H.J.6
  • 17
    • 0037414476 scopus 로고    scopus 로고
    • Strain specificity of the immune response of pigs following vaccination with various strains of porcine reproductive and respiratory syndrome virus
    • Mengeling, W.L.; Lager, K.M.; Vorwald, A.C.; Koehler, K.J. Strain specificity of the immune response of pigs following vaccination with various strains of porcine reproductive and respiratory syndrome virus. Vet. Microbiol. 2003, 93, 13-24.
    • (2003) Vet. Microbiol , vol.93 , pp. 13-24
    • Mengeling, W.L.1    Lager, K.M.2    Vorwald, A.C.3    Koehler, K.J.4
  • 18
    • 40249113295 scopus 로고    scopus 로고
    • Similarity of European porcine reproductive and respiratory syndrome virus strains to vaccine strain is not necessarily predictive of the degree of protective immunity conferred
    • Prieto, C.; Alvarez, E.; Martinez-Lobo, F.J.; Simarro, I.; Castro, J.M. Similarity of European porcine reproductive and respiratory syndrome virus strains to vaccine strain is not necessarily predictive of the degree of protective immunity conferred. Vet. J. 2008, 175, 356-363.
    • (2008) Vet. J , vol.175 , pp. 356-363
    • Prieto, C.1    Alvarez, E.2    Martinez-Lobo, F.J.3    Simarro, I.4    Castro, J.M.5
  • 19
    • 84870492848 scopus 로고    scopus 로고
    • Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection
    • Diaz, I.; Gimeno, M.; Darwich, L.; Navarro, N.; Kuzemtseva, L.; Lopez, S.; Galindo, I.; Segales, J.; Martin, M.; Pujols, J. et al. Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection. Vet. Res. 2012, 43, 30.
    • (2012) Vet. Res , vol.43 , pp. 30
    • Diaz, I.1    Gimeno, M.2    Darwich, L.3    Navarro, N.4    Kuzemtseva, L.5    Lopez, S.6    Galindo, I.7    Segales, J.8    Martin, M.9    Pujols, J.10
  • 20
    • 33746274050 scopus 로고    scopus 로고
    • Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs
    • Diaz, I.; Darwich, L.; Pappaterra, G.; Pujols, J.; Mateu, E. Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs. Virology 2006, 351, 249-259.
    • (2006) Virology , vol.351 , pp. 249-259
    • Diaz, I.1    Darwich, L.2    Pappaterra, G.3    Pujols, J.4    Mateu, E.5
  • 21
    • 46149122330 scopus 로고    scopus 로고
    • The challenge of PRRS immunology
    • Mateu, E.; Diaz, I. The challenge of PRRS immunology. Vet. J. 2008, 177, 345-351.
    • (2008) Vet. J , vol.177 , pp. 345-351
    • Mateu, E.1    Diaz, I.2
  • 22
    • 48649108828 scopus 로고    scopus 로고
    • Identification of immunodominant T-cell epitopes present in glycoprotein 5 of the North American genotype of porcine reproductive and respiratory syndrome virus
    • Vashisht, K.; Goldberg, T.L.; Husmann, R.J.; Schnitzlein, W.; Zuckermann, F.A. Identification of immunodominant T-cell epitopes present in glycoprotein 5 of the North American genotype of porcine reproductive and respiratory syndrome virus. Vaccine 2008, 26, 4747-4753.
    • (2008) Vaccine , vol.26 , pp. 4747-4753
    • Vashisht, K.1    Goldberg, T.L.2    Husmann, R.J.3    Schnitzlein, W.4    Zuckermann, F.A.5
  • 23
    • 68949166049 scopus 로고    scopus 로고
    • In silico prediction and ex vivo evaluation of potential T-cell epitopes in glycoproteins 4 and 5 and nucleocapsid protein of genotype-I (European) of porcine reproductive and respiratory syndrome virus
    • Diaz, I.; Pujols, J.; Ganges, L.; Gimeno, M.; Darwich, L.; Domingo, M.; Mateu, E. In silico prediction and ex vivo evaluation of potential T-cell epitopes in glycoproteins 4 and 5 and nucleocapsid protein of genotype-I (European) of porcine reproductive and respiratory syndrome virus. Vaccine 2009, 27, 5603-5611.
    • (2009) Vaccine , vol.27 , pp. 5603-5611
    • Diaz, I.1    Pujols, J.2    Ganges, L.3    Gimeno, M.4    Darwich, L.5    Domingo, M.6    Mateu, E.7
  • 24
    • 79956299886 scopus 로고    scopus 로고
    • Identification of immunodominant T-cell epitopes in membrane protein of highly pathogenic porcine reproductive and respiratory syndrome virus
    • Wang, Y.X.; Zhou, Y.J.; Li, G.X.; Zhang, S.R.; Jiang, Y.F.; Xu, A.T.; Yu, H.; Wang, M.M.; Yan, L.P.; Tong, G.Z. Identification of immunodominant T-cell epitopes in membrane protein of highly pathogenic porcine reproductive and respiratory syndrome virus. Virus. Res. 2011, 158, 108-115.
    • (2011) Virus. Res , vol.158 , pp. 108-115
    • Wang, Y.X.1    Zhou, Y.J.2    Li, G.X.3    Zhang, S.R.4    Jiang, Y.F.5    Xu, A.T.6    Yu, H.7    Wang, M.M.8    Yan, L.P.9    Tong, G.Z.10
  • 25
    • 84867205083 scopus 로고    scopus 로고
    • Location of T-cell epitopes in nonstructural proteins 9 and 10 of type-II porcine reproductive and respiratory syndrome virus
    • Parida, R.; Choi, I.S.; Peterson, D.A.; Pattnaik, A.K.; Laegreid, W.; Zuckermann, F.A.; Osorio, F.A. Location of T-cell epitopes in nonstructural proteins 9 and 10 of type-II porcine reproductive and respiratory syndrome virus. Virus Res. 2012, 169, 13-21.
    • (2012) Virus Res , vol.169 , pp. 13-21
    • Parida, R.1    Choi, I.S.2    Peterson, D.A.3    Pattnaik, A.K.4    Laegreid, W.5    Zuckermann, F.A.6    Osorio, F.A.7
  • 26
    • 0037086525 scopus 로고    scopus 로고
    • CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons
    • MacDonald, A.J.; Duffy, M.; Brady, M.T.; McKiernan, S.; Hall, W.; Hegarty, J.; Curry, M.; Mills, K.H. CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons. J. Infect. Dis. 2002, 185, 720-727.
    • (2002) J. Infect. Dis , vol.185 , pp. 720-727
    • Macdonald, A.J.1    Duffy, M.2    Brady, M.T.3    McKiernan, S.4    Hall, W.5    Hegarty, J.6    Curry, M.7    Mills, K.H.8
  • 27
    • 85172047829 scopus 로고    scopus 로고
    • Identification of Porcine Reproductive and Respiratory Syndrome Virus Structural Protein Epitopes that induce CD4+CD25+FoxP3+ Regulatory T Cells in vitro
    • Chicago, IL, USA
    • Todd, M.; Cecere, T.; LeRoith, T. Identification of Porcine Reproductive and Respiratory Syndrome Virus Structural Protein Epitopes that induce CD4+CD25+FoxP3+ Regulatory T Cells in vitro. In Proceedings of the International PRRS Symposium, Chicago, IL, USA, 2010; p. 57.
    • (2010) Proceedings of the International PRRS Symposium , pp. 57
    • Todd, M.1    Cecere, T.2    Leroith, T.3
  • 29
    • 0036137241 scopus 로고    scopus 로고
    • ProPred: Prediction of HLA-DR binding sites
    • Singh, H.; Raghava, G.P. ProPred: prediction of HLA-DR binding sites. Bioinformatics 2001, 17, 1236-1237.
    • (2001) Bioinformatics , vol.17 , pp. 1236-1237
    • Singh, H.1    Raghava, G.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.