Management, clinical outcomes, and complications of shield ulcers in vernal keratoconjunctivitis

American Journal of Ophthalmology

Volumn 155, Issue 3, 2013, Pages 550-559.e1

  Reddy, Jagadesh C ^a   Basu, Sayan ^a   Saboo, Ujwala S ^a   Murthy, Somasheila I ^a   Vaddavalli, Pravin K ^a   Sangwan, Virender S ^a  

^a L V PRASAD EYE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ALGORITHM; AMNION; AMNIOTIC MEMBRANE TRANSPLANTATION; ARTICLE; BACTERIAL KERATITIS; BREVIBACTERIUM; CORYNEBACTERIUM; DEBRIDEMENT; EPITHELIZATION; EYE; FEMALE; HUMAN; INDIA; INTERVENTION STUDY; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; NEISSERIA MENINGITIDIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SHIELD ULCER; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PNEUMONIA; TRANSPLANTATION; ULCER; VERNAL CONJUNCTIVITIS; VISUAL ACUITY;

EID: 84873722592     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2012.09.014     Document Type: Article

References (38)

1. S. Bonini, S. Bonini, and A. Lambiase Vernal keratoconjunctivitis revisited: a case series of 195 patients with long-term follow-up Ophthalmology 107 6 2000 1157 1163
2. A. Leonardi, F. Busca, and L. Motterle Case series of 406 vernal keratoconjunctivitis patients: a demographic and epidemiological study Acta Ophthalmol Scand 84 3 2006 406 410
3. K.F. Tabbara Ocular complications of vernal keratoconjunctivitis Can J Ophthalmol 34 2 1999 88 92
4. B.R. Jones Vernal keratitis Trans Ophthalmol Soc U K 81 1981 215 228
5. I.J. Udell, G.J. Gleich, M.R. Allansmith, S.J. Ackerman, and M.B. Abelson Eosinophil granule major basic protein and Charcot-Leyden crystal protein in human tears Am J Ophthalmol 92 6 1981 824 828
6. A. Solomon, E. Zamir, S. Levartovsky, and J. Frucht-Pery Surgical management of corneal plaques in vernal keratoconjunctivitis: a clinicopathologic study Cornea 23 6 2004 608 612
7. N. Kerr, and G.A. Stern Bacterial keratitis associated with vernal keratoconjunctivitis Cornea 11 4 1992 355 359
8. M.S. Sridhar, U. Gopinathan, and G.N. Rao Fungal keratitis associated with vernal keratoconjunctivitis Cornea 22 1 2003 80 81
9. V. Jain, K. Mhatre, A.G. Nair, D. Shome, and S. Natarajan Aspergillus keratitis in vernal shield ulcer - a case report and review Int Ophthalmol 30 6 2010 641 644
10. J.A. Cameron, and P.B. Mullaney Amblyopia resulting from Shield ulcers and plaques of the cornea in vernal keratoconjunctivitis J Pediatr Ophthalmol Strabismus 34 4 1997 261 262
11. R.J. Buckley Vernal keratopathy and its management Trans Ophthalmol Soc U K 101 Pt 2 1981 234 238
12. D.S. Holsclaw, J.P. Whitcher, I.G. Wong, and T.P. Margolis Supratarsal injection of corticosteroid in the treatment of refractory vernal keratoconjunctivitis Am J Ophthalmol 121 3 1996 243 249
13. A. Cetinkaya, Y.A. Akova, D. Dursun, and A. Pelit Topical cyclosporine in the management of Shield ulcers Cornea 23 2 2004 194 200
14. S. Kumar Combined therapy for vernal Shield ulcer Clin Exp Optom 91 1 2008 111 114
15. J.A. Cameron Shield ulcers and plaques of the cornea in vernal keratoconjunctivitis Ophthalmology 102 6 1995 985 993
16. Z. Ozbek, A.Z. Burakgazi, and C.J. Rapuano Rapid healing of vernal Shield ulcer after surgical debridement: a case report Cornea 25 4 2006 472 473
17. M.S. Sridhar, V.S. Sangwan, A.K. Bansal, and G.N. Rao Amniotic membrane transplantation in the management of Shield ulcers of vernal keratoconjunctivitis Ophthalmology 108 7 2001 1218 1222
18. D. Jiang, M. Zhang, and Y. Hu Resection and cryotherapy combined with amniotic membrane transplantation for the treatment of vernal keratoconjunctivitis with giant papillae J Huazhong Univ Sci Technolog Med Sci 26 5 2006 618 620
19. J.A. Cameron, S.R. Antonios, and I.A. Badr Excimer laser phototherapeutic keratectomy for Shield ulcers and corneal plaques in vernal keratoconjunctivitis J Refract Surg 11 1 1995 31 35
20. S.H. Lee, and S.C. Tseng Amniotic membrane transplantation for persistent epithelial defects with ulceration Am J Ophthalmol 123 3 1997 303 312
21. E. Neumann, M.J. Gutmann, N. Blumenkrantz, and I.C. Michaelson A review of four hundred cases of vernal conjunctivitis Am J Ophthalmol 47 2 1959 166 172
22. S. De Smedt, J. Nkurikiye, and Y. Fonteyne Topical ciclosporin in the treatment of vernal keratoconjunctivitis in Rwanda, Central Africa: a prospective, randomised, double-masked, controlled clinical trial Br J Ophthalmol 96 3 2012 323 328
23. S.D. Trocmé, G.M. Kephart, W.M. Bourne, R.J. Buckley, and G.J. Gleich Eosinophil granule major basic protein deposition in corneal ulcers associated with vernal keratoconjunctivitis Am J Ophthalmol 115 5 1993 640 643
24. S.D. Trocmé, G.M. Kephart, M.R. Allansmith, W.M. Bourne, and G.J. Gleich Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-Associated giant papillary conjunctivitis Am J Ophthalmol 108 1 1989 57 63
25. G.J. Gleich, E. Frigas, D.A. Loegering, D.L. Wassom, and D. Steinmuller Cytotoxic properties of the eosinophil major basic protein J Immunol 123 6 1979 2925 2927
26. L.L. Thomas, L.M. Zheutlin, and G.J. Gleich Pharmacological control of human basophil histamine release stimulated by eosinophil granule major basic protein Immunology 66 4 1989 611 615
27. J.N. Moy, G.J. Gleich, and L.L. Thomas Noncytotoxic activation of neutrophils by eosinophil granule major basic protein. Effect on superoxide anion generation and lysosomal enzyme release J Immunol 145 8 1990 2626 2632
28. S.D. Trocmé, G.J. Gleich, G.M. Kephart, and J.D. Zieske Eosinophil granule major basic protein inhibition of corneal epithelial wound healing Invest Ophthalmol Vis Sci 35 7 1994 3051 3056
29. S.D. Trocmé, C.K. Hallberg, K.S. Gill, G.J. Gleich, S.K. Tyring, and M.M. Brysk Effects of eosinophil granule proteins on human corneal epithelial cell viability and morphology Invest Ophthalmol Vis Sci 38 3 1997 593 599
30. N.S. Rice, D. Easty, and A. Garner Vernal kerato-conjunctivitis and its management Trans Ophthalmol Soc U K 91 1971 483 489
31. A.H.S. Rahi, R. Buckley, and I. Grierson Pathology of corneal plaques in vernal keratoconjunctivitis G.R. O'Connor, J.W. Chandler, Advances in Immunology and Immunopathology of the Eye 1985 Masson New York 91 94
32. V.S. Sangwan, and S.C. Tseng New perspectives in ocular surface disorders. An integrated approach for diagnosis and management Ind J Ophthalmol 49 3 2001 153 168
33. S. Shimmura, J. Shimazaki, Y. Ohashi, and K. Tsubota Anti-inflammatory effects of amniotic membrane transplantation in ocular surface disorders Cornea 20 4 2001 408 413
34. P. Rapacz, J. Tedesco, P.C. Donshik, and M. Ballow Tear lysozyme and lactoferrin levels in giant papillary conjunctivitis and vernal conjunctivitis CLAO J 14 4 1988 207 209
35. S.J. Tuft, J.K. Dart, and M. Kemeny Limbal vernal keratoconjunctivitis: clinical characteristics and immunoglobulin E expression compared with palpebral vernal Eye (Lond) 3 Pt 4 1989 420 427
36. H.S. Dua, and A. Azuara-Blanco Limbal stem cells of the corneal epithelium Surv Ophthalmol 44 5 2000 415 425
37. V.S. Sangwan, V. Jain, G.K. Vemuganti, and S.I. Murthy Vernal keratoconjunctivitis with limbal stem cell deficiency Cornea 30 5 2011 491 496
38. V.S. Sangwan, S.I. Murthy, G.K. Vemuganti, A.K. Bansal, N. Gangopadhyay, and G.N. Rao Cultivated corneal epithelial transplantation for severe ocular surface disease in vernal keratoconjunctivitis Cornea 24 4 2005 426 430