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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 5, 2013, Pages 1347-1350

Discovery of olmesartan hexetil: A new potential prodrug of olmesartan

(13) El Gamal, Mohammed I a,b,c Anbar, Hanan S a Chung, Hye Jin a Kim, Hyun Il d Cho, Young Jin d Lee, Bong Sang d Lee, Sun Ahe d Moon, Ji Yun d Lee, Dong Jin d Kwon, Dow d Choi, Won Jai d Jeon, Hong Ryeol d Oh, Chang Hyun a,b

a Korea Institute of Science and Technology (South Korea)

b University of Science and Technology (UST) (South Korea)

c University of Mansoura (Egypt)

d CTC Bio Inc (South Korea)

Author keywords

Antihypertensive; Ester; Olmesartan hexetil; Olmesartan medoxomil; Pharmacokinetics; Prodrug

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CANDESARTAN; OLMESARTAN; OLMESARTAN HEXETIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STABILITY; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; LIVER MICROSOME; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHARMACOLOGICAL PARAMETERS; RAT; STOMACH JUICE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOLOGICAL AVAILABILITY; DRUG DISCOVERY; DRUG STABILITY; ESTERS; GASTRIC JUICE; IMIDAZOLES; MALE; MICROSOMES, LIVER; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; TETRAZOLES;

RATTUS;

EID: 84873714069 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.12.090 Document Type: Article

Times cited : (4)

References (19)

1
- 33646251621
- A. Ferro, R. Gilbert, and H. Krum Int. J. Clin. Pract. 60 2006 577
- (2006) Int. J. Clin. Pract. , vol.60 , pp. 577
- Ferro, A.¹ Gilbert, R.² Krum, H.³

2
- 39849103415
- M. Fukuda, T. Yamanaka, M. Mizuno, M. Motokawa, Y. Shirasawa, S. Miyagi, T. Nishio, A. Yoshida, and G. Kimura J. Hypertens. 26 2008 583
- (2008) J. Hypertens. , vol.26 , pp. 583
- Fukuda, M.¹ Yamanaka, T.² Mizuno, M.³ Motokawa, M.⁴ Shirasawa, Y.⁵ Miyagi, S.⁶ Nishio, T.⁷ Yoshida, A.⁸ Kimura, G.⁹

3
- 0033386873
- M.A. Weber Am. J. Hypertens. 12 1999 189S
- (1999) Am. J. Hypertens. , vol.12
- Weber, M.A.¹

4
- 0033988042
- T. Unger Am. Heart J. 139 2000 S2
- (2000) Am. Heart J. , vol.139 , pp. 2
- Unger, T.¹

5
- 77957561801
- A.M. Bell, and D. Nykamp Therapeutics 1 2009 1
- (2009) Therapeutics , vol.1 , pp. 1
- Bell, A.M.¹ Nykamp, D.²

6
- 27344455433
- D.E. Mire, T.N. Silfani, and M.K. Pugsley J. Cardiovasc. Pharmacol. 46 2005 585
- (2005) J. Cardiovasc. Pharmacol. , vol.46 , pp. 585
- Mire, D.E.¹ Silfani, T.N.² Pugsley, M.K.³

7
- 33846043074
- J. Agata, N. Ura, H. Yoshida, Y. Shinshi, H. Sasaki, M. Hyakkoku, S. Taniguchi, and K. Shimamoto Hypertens. Res. 29 2006 865
- (2006) Hypertens. Res. , vol.29 , pp. 865
- Agata, J.¹ Ura, N.² Yoshida, H.³ Shinshi, Y.⁴ Sasaki, H.⁵ Hyakkoku, M.⁶ Taniguchi, S.⁷ Shimamoto, K.⁸

8
- 0030049822
- H. Yanagisawa, Y. Amemiya, T. Kanazaki, Y. Shimoji, K. Fujimoto, Y. Kitahara, T. Sada, M. Mizuno, M. Ikeda, S. Miyamoto, Y. Furukawa, and H. Koike J. Med. Chem. 39 1996 323
- (1996) J. Med. Chem. , vol.39 , pp. 323
- Yanagisawa, H.¹ Amemiya, Y.² Kanazaki, T.³ Shimoji, Y.⁴ Fujimoto, K.⁵ Kitahara, Y.⁶ Sada, T.⁷ Mizuno, M.⁸ Ikeda, M.⁹ Miyamoto, S.¹⁰ Furukawa, Y.¹¹ Koike, H.¹²

9
- 84891954605
- S.-F. Ma, M. Anraku, Y. Iwao, K. Yamasaki, U. Kragh-Hansen, N. Yamaotsu, S. Hirono, T. Ikeda, and M. Otagiri Drug Metab. Dispos. 2005 1911 33
- (1911) Drug Metab. Dispos. , vol.2005 , pp. 33
- Ma, S.-F.¹ Anraku, M.² Iwao, Y.³ Yamasaki, K.⁴ Kragh-Hansen, U.⁵ Yamaotsu, N.⁶ Hirono, S.⁷ Ikeda, T.⁸ Otagiri, M.⁹

10
- 77951247279
- T. Ishizuka, I. Fujimori, M. Kato, C. Noji-Sakikawa, M. Saito, Y. Yoshigae, K. Kubota, A. Kurihara, T. Izumi, T. Ikeda, and O. Okazaki J. Biol. Chem. 285 2010 11892
- (2010) J. Biol. Chem. , vol.285 , pp. 11892
- Ishizuka, T.¹ Fujimori, I.² Kato, M.³ Noji-Sakikawa, C.⁴ Saito, M.⁵ Yoshigae, Y.⁶ Kubota, K.⁷ Kurihara, A.⁸ Izumi, T.⁹ Ikeda, T.¹⁰ Okazaki, O.¹¹

11
- 84856020408
- T. Ishizuka, I. Fujimori, A. Nishida, H. Sakurai, Y. Yoshigae, K. Nakahara, A. Kurihara, T. Ikeda, and T. Izumi Drug Metab. Dispos. 40 2012 374
- (2012) Drug Metab. Dispos. , vol.40 , pp. 374
- Ishizuka, T.¹ Fujimori, I.² Nishida, A.³ Sakurai, H.⁴ Yoshigae, Y.⁵ Nakahara, K.⁶ Kurihara, A.⁷ Ikeda, T.⁸ Izumi, T.⁹

12
- 77957561249
- J.-H. Park, J.-S. Chang, M.I. El-Gamal, W.-K. Choi, W.S. Lee, H.J. Chung, H.-I. Kim, Y.-J. Cho, B.S. Lee, H.-R. Jeon, Y.-S. Lee, Y.W. Choi, J. Lee, and C.-H. Oh Bioorg. Med. Chem. Lett. 20 2010 5895
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 5895
- Park, J.-H.¹ Chang, J.-S.² El-Gamal, M.I.³ Choi, W.-K.⁴ Lee, W.S.⁵ Chung, H.J.⁶ Kim, H.-I.⁷ Cho, Y.-J.⁸ Lee, B.S.⁹ Jeon, H.-R.¹⁰ Lee, Y.-S.¹¹ Choi, Y.W.¹² Lee, J.¹³ Oh, C.-H.¹⁴

13
- 80052942627
- J.-S. Chang, M.I. El-Gamal, W.S. Lee, H.S. Anbar, H.J. Chung, H.-I. Kim, Y.-J. Cho, B.S. Lee, S.A. Lee, J.Y. Moon, D.J. Lee, H.-R. Jeon, J. Lee, Y.K. Choi, and C.-H. Oh Eur. J. Med. Chem. 46 2011 3564
- (2011) Eur. J. Med. Chem. , vol.46 , pp. 3564
- Chang, J.-S.¹ El-Gamal, M.I.² Lee, W.S.³ Anbar, H.S.⁴ Chung, H.J.⁵ Kim, H.-I.⁶ Cho, Y.-J.⁷ Lee, B.S.⁸ Lee, S.A.⁹ Moon, J.Y.¹⁰ Lee, D.J.¹¹ Jeon, H.-R.¹² Lee, J.¹³ Choi, Y.K.¹⁴ Oh, C.-H.¹⁵

14
- 0027327826
- K. Kubo, Y. Kohara, Y. Yoshimura, Y. Inada, Y. Shibouta, Y. Furukawa, T. Kato, K. Nishikawa, and T. Naka J. Med. Chem. 36 1993 2343
- (1993) J. Med. Chem. , vol.36 , pp. 2343
- Kubo, K.¹ Kohara, Y.² Yoshimura, Y.³ Inada, Y.⁴ Shibouta, Y.⁵ Furukawa, Y.⁶ Kato, T.⁷ Nishikawa, K.⁸ Naka, T.⁹

15
- 84891928107
- http://www.organic-chemistry.org/prog/peo/.

16
- 84891941145
- http://www.molinspiration.com/cgi-bin/properties.

17
- 84873739699
- PCT Int. Appl. WO 2007/148344 A2, December 27
- Ramanjaneyulu, G. S.; Mohan, B.; Ray, P. C.; Sethi, M. K.; Rawat, V. S.; Krishna, Y. R.; Lakshminarayana, V.; Srinivas, M. PCT Int. Appl. WO 2007/148344 A2, December 27, 2007.
- (2007)
- Ramanjaneyulu . G, S.¹ Mohan, B.² Ray . P, C.³ Sethi . M, K.⁴ Rawat . V, S.⁵ Krishna . Y, R.⁶ Lakshminarayana, V.⁷ Srinivas, M.⁸

18
- 72049114958
- B.S. Lee, M.J. Kang, W.S. Choi, Y.B. Choi, H.S. Kim, S.K. Lee, J. Lee, and Y.W. Choi Arch. Pharm. Res. 32 2009 1629
- (2009) Arch. Pharm. Res. , vol.32 , pp. 1629
- Lee, B.S.¹ Kang, M.J.² Choi, W.S.³ Choi, Y.B.⁴ Kim, H.S.⁵ Lee, S.K.⁶ Lee, J.⁷ Choi, Y.W.⁸

19
- 0017884783
- K. Yeh, and K. Kwan J. Pharmacokinet. Biopharm. 6 1978 79
- (1978) J. Pharmacokinet. Biopharm. , vol.6 , pp. 79
- Yeh, K.¹ Kwan, K.²

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