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Volumn 44, Issue 3, 2013, Pages 346-356

Bone marrow morphology predicts additional chromosomal abnormalities in patients with myelodysplastic syndrome with del(5q)

Author keywords

del(5q); Isolated 5q deletion; Karyotype; Lenalidomide; Myelodysplastic syndrome

Indexed keywords

JANUS KINASE 2;

EID: 84873711387     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.05.022     Document Type: Article
Times cited : (14)

References (43)
  • 1
    • 0022869420 scopus 로고
    • Chromosome abnormalities in the myelodysplastic syndromes
    • S. Heim, and F. Mitelman Chromosome abnormalities in the myelodysplastic syndromes Clin Haematol 15 1986 1003 1021
    • (1986) Clin Haematol , vol.15 , pp. 1003-1021
    • Heim, S.1    Mitelman, F.2
  • 2
    • 57649119892 scopus 로고    scopus 로고
    • Cytogenetic abnormalities in a series of 1,029 patients with primary myelodysplastic syndromes: A report from the US with a focus on some undefined single chromosomal abnormalities
    • O. Pozdnyakova, P.M. Miron, and G. Tang Cytogenetic abnormalities in a series of 1,029 patients with primary myelodysplastic syndromes: a report from the US with a focus on some undefined single chromosomal abnormalities Cancer 113 2008 3331 3340
    • (2008) Cancer , vol.113 , pp. 3331-3340
    • Pozdnyakova, O.1    Miron, P.M.2    Tang, G.3
  • 3
    • 23744513172 scopus 로고    scopus 로고
    • Incidence and prognostic significance of karyotype abnormalities in de novo primary myelodysplastic syndromes: A study on 331 patients from a single institution
    • P. Bernasconi, C. Klersy, and M. Boni Incidence and prognostic significance of karyotype abnormalities in de novo primary myelodysplastic syndromes: a study on 331 patients from a single institution Leukemia 19 2005 1424 1431
    • (2005) Leukemia , vol.19 , pp. 1424-1431
    • Bernasconi, P.1    Klersy, C.2    Boni, M.3
  • 4
    • 25444484409 scopus 로고    scopus 로고
    • Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes
    • F. Sole, E. Luno, and C. Sanzo Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes Haematologica 90 2005 1168 1178
    • (2005) Haematologica , vol.90 , pp. 1168-1178
    • Sole, F.1    Luno, E.2    Sanzo, C.3
  • 5
    • 39649094569 scopus 로고    scopus 로고
    • New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: Evidence from a core dataset of 2124 patients
    • D. Haase, U. Germing, and J. Schanz New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients Blood 110 2007 4385 4395
    • (2007) Blood , vol.110 , pp. 4385-4395
    • Haase, D.1    Germing, U.2    Schanz, J.3
  • 9
    • 10744229499 scopus 로고    scopus 로고
    • Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31
    • A.A. Giagounidis, U. Germing, and S. Haase Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31 Leukemia 18 2004 113 119
    • (2004) Leukemia , vol.18 , pp. 113-119
    • Giagounidis, A.A.1    Germing, U.2    Haase, S.3
  • 10
    • 0029065975 scopus 로고
    • Hematological features of patients with myelodysplastic syndromes associated with a chromosome 5q deletion
    • S. Lewis, D. Oscier, and J. Boultwood Hematological features of patients with myelodysplastic syndromes associated with a chromosome 5q deletion Am J Hematol 49 1995 194 200
    • (1995) Am J Hematol , vol.49 , pp. 194-200
    • Lewis, S.1    Oscier, D.2    Boultwood, J.3
  • 11
    • 51449104487 scopus 로고    scopus 로고
    • Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: Clinicopathologic correlations and new insights from the pre-lenalidomide era
    • S.G. Holtan, R. Santana-Davila, and G.W. Dewald Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: clinicopathologic correlations and new insights from the pre-lenalidomide era Am J Hematol 83 2008 708 713
    • (2008) Am J Hematol , vol.83 , pp. 708-713
    • Holtan, S.G.1    Santana-Davila, R.2    Dewald, G.W.3
  • 12
    • 77954658029 scopus 로고    scopus 로고
    • WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: Survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations
    • M.M. Patnaik, T.L. Lasho, and C.M. Finke WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations Leukemia 24 2010 1283 1289
    • (2010) Leukemia , vol.24 , pp. 1283-1289
    • Patnaik, M.M.1    Lasho, T.L.2    Finke, C.M.3
  • 13
    • 0027458441 scopus 로고
    • The 5q - Syndrome: A single-institution study of 43 consecutive patients
    • P. Mathew, A. Tefferi, and G.W. Dewald The 5q - syndrome: a single-institution study of 43 consecutive patients Blood 81 1993 1040 1045
    • (1993) Blood , vol.81 , pp. 1040-1045
    • Mathew, P.1    Tefferi, A.2    Dewald, G.W.3
  • 14
    • 78651307662 scopus 로고    scopus 로고
    • Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q
    • M. Mallo, J. Cervera, and J. Schanz Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q Leukemia 25 2011 110 120
    • (2011) Leukemia , vol.25 , pp. 110-120
    • Mallo, M.1    Cervera, J.2    Schanz, J.3
  • 15
    • 33749438404 scopus 로고    scopus 로고
    • Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
    • A. List, G. Dewald, and J. Bennett Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion N Engl J Med 355 2006 1456 1465
    • (2006) N Engl J Med , vol.355 , pp. 1456-1465
    • List, A.1    Dewald, G.2    Bennett, J.3
  • 16
    • 13444256401 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in myelodysplastic syndromes
    • A. List, S. Kurtin, and D.J. Roe Efficacy of lenalidomide in myelodysplastic syndromes N Engl J Med 352 2005 549 557
    • (2005) N Engl J Med , vol.352 , pp. 549-557
    • List, A.1    Kurtin, S.2    Roe, D.J.3
  • 17
    • 38349088899 scopus 로고    scopus 로고
    • Identification of RPS14 as a 5q - Syndrome gene by RNA interference screen
    • B.L. Ebert, J. Pretz, and J. Bosco Identification of RPS14 as a 5q - syndrome gene by RNA interference screen Nature 451 2008 335 339
    • (2008) Nature , vol.451 , pp. 335-339
    • Ebert, B.L.1    Pretz, J.2    Bosco, J.3
  • 18
    • 73849128091 scopus 로고    scopus 로고
    • A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q - Syndrome
    • J.L. Barlow, L.F. Drynan, and D.R. Hewett A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q - syndrome Nat Med 16 2010 59 66
    • (2010) Nat Med , vol.16 , pp. 59-66
    • Barlow, J.L.1    Drynan, L.F.2    Hewett, D.R.3
  • 19
    • 33745213401 scopus 로고    scopus 로고
    • The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow
    • W. Ingram, N.C. Lea, and J. Cervera The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow Leukemia 20 2006 1319 1321
    • (2006) Leukemia , vol.20 , pp. 1319-1321
    • Ingram, W.1    Lea, N.C.2    Cervera, J.3
  • 22
    • 0015090542 scopus 로고
    • Quantitation of bone marrow reticulin - A normal range
    • D.E. Bauermeister Quantitation of bone marrow reticulin - a normal range Am J Clin Pathol 56 1971 24 31
    • (1971) Am J Clin Pathol , vol.56 , pp. 24-31
    • Bauermeister, D.E.1
  • 23
    • 0018675904 scopus 로고
    • The reticulin content of bone marrow in acute leukaemia in adults
    • A. Manoharan, R. Horsley, and W.R. Pitney The reticulin content of bone marrow in acute leukaemia in adults Br J Haematol 43 1979 185 190
    • (1979) Br J Haematol , vol.43 , pp. 185-190
    • Manoharan, A.1    Horsley, R.2    Pitney, W.R.3
  • 25
    • 34247899182 scopus 로고    scopus 로고
    • Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders
    • Q. Chen, P. Lu, A.V. Jones, N.C. Cross, R.T. Silver, and Y.L. Wang Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders J Mol Diagn 9 2007 272 276
    • (2007) J Mol Diagn , vol.9 , pp. 272-276
    • Chen, Q.1    Lu, P.2    Jones, A.V.3    Cross, N.C.4    Silver, R.T.5    Wang, Y.L.6
  • 26
    • 45149113001 scopus 로고    scopus 로고
    • JAK2 Mutations are present in all cases of polycythemia vera
    • Y.L. Wang, K. Vandris, and A. Jones JAK2 Mutations are present in all cases of polycythemia vera Leukemia 22 2008 1289
    • (2008) Leukemia , vol.22 , pp. 1289
    • Wang, Y.L.1    Vandris, K.2    Jones, A.3
  • 28
    • 0003575142 scopus 로고    scopus 로고
    • Common toxicity criteria 1999: http://www.eortc.be/services/doc/ctc/ ctcv20-4-30-992.pdf.
    • (1999) Common Toxicity Criteria
  • 29
    • 80053956542 scopus 로고    scopus 로고
    • Treatment by Lenalidomide in lower risk myelodysplastic syndrome with 5q deletion - The GFM experience
    • F. Le Bras, M. Sebert, and C. Kelaidi Treatment by Lenalidomide in lower risk myelodysplastic syndrome with 5q deletion - the GFM experience Leuk Res 35 2011 1444 1448
    • (2011) Leuk Res , vol.35 , pp. 1444-1448
    • Le Bras, F.1    Sebert, M.2    Kelaidi, C.3
  • 30
    • 70449378917 scopus 로고    scopus 로고
    • The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: How does it relate to the original lenalidomide experience in MDS?
    • H. Kantarjian, S. O'Brien, and F. Ravandi The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: how does it relate to the original lenalidomide experience in MDS? Cancer 115 2009 5202 5209
    • (2009) Cancer , vol.115 , pp. 5202-5209
    • Kantarjian, H.1    O'Brien, S.2    Ravandi, F.3
  • 31
    • 0036235310 scopus 로고    scopus 로고
    • Myeloid disorders with deletion of 5q as the sole karyotypic abnormality: The clinical and pathologic spectrum
    • L.T. Washington, D. Doherty, A. Glassman, J. Martins, S. Ibrahim, and R. Lai Myeloid disorders with deletion of 5q as the sole karyotypic abnormality: the clinical and pathologic spectrum Leuk Lymphoma 43 2002 761 765
    • (2002) Leuk Lymphoma , vol.43 , pp. 761-765
    • Washington, L.T.1    Doherty, D.2    Glassman, A.3    Martins, J.4    Ibrahim, S.5    Lai, R.6
  • 32
    • 39749117093 scopus 로고    scopus 로고
    • Chromosome 5q deletion: Specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution
    • R. Santana-Davila, S.G. Holtan, and G.W. Dewald Chromosome 5q deletion: specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution Leuk Res 32 2008 407 411
    • (2008) Leuk Res , vol.32 , pp. 407-411
    • Santana-Davila, R.1    Holtan, S.G.2    Dewald, G.W.3
  • 33
    • 65449150965 scopus 로고    scopus 로고
    • Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: Results of a phase 2 study
    • L. Ades, S. Boehrer, and T. Prebet Efficacy and safety of lenalidomide in intermediate-2 or high-risk myelodysplastic syndromes with 5q deletion: results of a phase 2 study Blood 113 2009 3947 3952
    • (2009) Blood , vol.113 , pp. 3947-3952
    • Ades, L.1    Boehrer, S.2    Prebet, T.3
  • 34
    • 77649303359 scopus 로고    scopus 로고
    • Patients with del(5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression
    • G. Gohring, A. Giagounidis, and G. Busche Patients with del(5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression Ann Hematol 89 2010 365 374
    • (2010) Ann Hematol , vol.89 , pp. 365-374
    • Gohring, G.1    Giagounidis, A.2    Busche, G.3
  • 35
    • 40849131212 scopus 로고    scopus 로고
    • Unusual clonal evolution involving 5q in a case of myelodysplastic syndrome with deletion 5q 31 treated with lenalidomide
    • V. Eclache, A. Da Rocha, G. Le Roux, and P. Fenaux Unusual clonal evolution involving 5q in a case of myelodysplastic syndrome with deletion 5q 31 treated with lenalidomide Haematologica 93 2008 315 316
    • (2008) Haematologica , vol.93 , pp. 315-316
    • Eclache, V.1    Da Rocha, A.2    Le Roux, G.3    Fenaux, P.4
  • 36
    • 73149108856 scopus 로고    scopus 로고
    • Clonal heterogeneity in the 5q - Syndrome: P53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
    • M. Jadersten, L. Saft, and A. Pellagatti Clonal heterogeneity in the 5q - syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression Haematologica 94 2009 1762 1766
    • (2009) Haematologica , vol.94 , pp. 1762-1766
    • Jadersten, M.1    Saft, L.2    Pellagatti, A.3
  • 37
    • 77956516658 scopus 로고    scopus 로고
    • Persistent malignant stem cells in del(5q) myelodysplasia in remission
    • R. Tehranchi, P.S. Woll, and K. Anderson Persistent malignant stem cells in del(5q) myelodysplasia in remission N Engl J Med 363 2010 1025 1037
    • (2010) N Engl J Med , vol.363 , pp. 1025-1037
    • Tehranchi, R.1    Woll, P.S.2    Anderson, K.3
  • 38
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes
    • D.P. Steensma, G.W. Dewald, and T.L. Lasho The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes Blood 106 2005 1207 1209
    • (2005) Blood , vol.106 , pp. 1207-1209
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3
  • 39
    • 33748177825 scopus 로고    scopus 로고
    • The JAK2-V617F mutation and essential thrombocythemia features in a subset of patients with refractory anemia with ring sideroblasts (RARS)
    • M. Boissinot, R. Garand, M. Hamidou, and S. Hermouet The JAK2-V617F mutation and essential thrombocythemia features in a subset of patients with refractory anemia with ring sideroblasts (RARS) Blood 108 2006 1781 1782
    • (2006) Blood , vol.108 , pp. 1781-1782
    • Boissinot, M.1    Garand, R.2    Hamidou, M.3    Hermouet, S.4
  • 40
    • 33750299561 scopus 로고    scopus 로고
    • The JAK2 V617F mutation is rare in RARS but common in RARS-T
    • M.M. Ceesay, N.C. Lea, and W. Ingram The JAK2 V617F mutation is rare in RARS but common in RARS-T Leukemia 20 2006 2060 2061
    • (2006) Leukemia , vol.20 , pp. 2060-2061
    • Ceesay, M.M.1    Lea, N.C.2    Ingram, W.3
  • 41
    • 33846891352 scopus 로고    scopus 로고
    • 9/L) and ringed sideroblasts more than 15% considered as MDS/MPD, unclassifiable
    • 9/L) and ringed sideroblasts more than 15% considered as MDS/MPD, unclassifiable Blood 109 2007 1334 1335
    • (2007) Blood , vol.109 , pp. 1334-1335
    • Gattermann, N.1    Billiet, J.2    Kronenwett, R.3
  • 42
    • 77952097487 scopus 로고    scopus 로고
    • JAK2(V617F) mutation in myelodysplastic syndrome (MDS) with del(5q) arises in genetically discordant clones
    • L. Sokol, G. Caceres, K. Rocha, K.J. Stockero, D.W. Dewald, and A.F. List JAK2(V617F) mutation in myelodysplastic syndrome (MDS) with del(5q) arises in genetically discordant clones Leuk Res 34 2010 821 823
    • (2010) Leuk Res , vol.34 , pp. 821-823
    • Sokol, L.1    Caceres, G.2    Rocha, K.3    Stockero, K.J.4    Dewald, D.W.5    List, A.F.6
  • 43
    • 77649282030 scopus 로고    scopus 로고
    • JAK2 V617F mutation is associated with 5q - Syndrome in Chinese
    • K.F. Wong, W.S. Wong, L.L. Siu, T.C. Lau, and N.P. Chan JAK2 V617F mutation is associated with 5q - syndrome in Chinese Leuk Lymphoma 50 2009 1333 1335
    • (2009) Leuk Lymphoma , vol.50 , pp. 1333-1335
    • Wong, K.F.1    Wong, W.S.2    Siu, L.L.3    Lau, T.C.4    Chan, N.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.