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Volumn 21, Issue 5, 2013, Pages 1199-1208
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9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro
a
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Author keywords
(Phosphonomethoxy)propyl; Acyclic nucleoside phosphonates; Antivirals; HIV; PMPDAP; Prodrugs; Purine
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Indexed keywords
1 [6 AMINO 2 [(2 HYDROXYPROPYL)AMINO] 9H PURIN 9 YL]PROPAN 2 OL;
1 [6 AMINO 2 [2 (HYDROXYPROPYL)AMINO] 9H PURIN 9 YL]PROPAN 2 OL;
9 (2 HYDROXYPROPYL) 2,6 DIAMINOPURINE;
9 (PROP 1 EN 1 YL) 9H PURINE 2,6 DIAMINE;
9 [2 (PHOSPHONOMETHOXY)PROPYL] 2,6 DIAMINOPURINE;
9 [2 (PHOSPHONOMETHOXY)PROPYL] N6 PHOSPHONOMETHYL 2,6 DIAMINOPURINE;
ALKOXYLALKYL(HEXADECYLOXYPROPYL)MONOESTER;
ANTIRETROVIRUS AGENT;
BIS(HEXADECYLOXYPROPYL)ESTER;
CARBONIC ACID;
ETOMIDATE;
HEXADECYLOXYPROPYL ESTER;
N (6 AMINO 9 (2 HYDROXYPROPYL) 9H PURIN 2 YL)FORNAMIDE;
PRODRUG;
PROPANEDIOL CARBONATE;
UNCLASSIFIED DRUG;
ANTIVIRAL ACTIVITY;
ARTICLE;
BIOLOGICAL ACTIVITY;
CAPILLARY ELECTROPHORESIS;
CELL CULTURE;
CHIRAL CAPILLARY ELECTROPHORESIS;
CONTROLLED STUDY;
DRUG BIOAVAILABILITY;
ENANTIOMER;
FELINE IMMUNODEFICIENCY VIRUS;
HUMAN;
HUMAN CELL;
HUMAN IMMUNODEFICIENCY VIRUS;
IN VITRO STUDY;
NUCLEOPHILICITY;
SYNTHESIS;
VIRUS REPLICATION;
ADENINE;
ANTIVIRAL AGENTS;
HIV-1;
IMMUNODEFICIENCY VIRUS, FELINE;
ORGANOPHOSPHORUS COMPOUNDS;
PRODRUGS;
STEREOISOMERISM;
FELINE IMMUNODEFICIENCY VIRUS;
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EID: 84873703456
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.12.044 Document Type: Article |
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Times cited : (15)
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References (19)
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