Burden of illness associated with painful diabetic peripheral neuropathy among adults seeking treatment in the US: Results from a retrospective chart review and cross-sectional survey

Diabetes, Metabolic Syndrome and Obesity

Volumn 6, Issue , 2013, Pages 79-92

  Sadosky, Alesia ^a   Schaefer, Caroline ^b   Mann, Rachael ^c   Bergstrom, Felicia ^b   Baik, Rebecca ^b   Parsons, Bruce ^a   Nalamachu, Srinivas ^d   Nieshoff, Edward ^e   Stacey, Brett R ^f   Anschel, Alan ^g   Tuchman, Michael ^h  

^a PFIZER INC   (United States)

^b Covance Market Access Services Inc   (United States)

^c UK   (United States)

^d Clinical Research   (United States)

^e WAYNE STATE UNIVERSITY   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^g REHABILITATION INSTITUTE OF CHICAGO   (United States)

^h Palm Beach Neurological Center   (United States)

Author keywords

Burden of illness; Costs; Health care resource use; Pain assessment; Painful diabetic peripheral neuropathy; Productivity; Quality of life; Treatment patterns

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN; HYDROCODONE PLUS PARACETAMOL; IBUPROFEN; MELOXICAM; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE DERIVATIVE; OXYCODONE; OXYCODONE PLUS PARACETAMOL; PREGABALIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANXIETY; BURDEN OF ILLNESS; COMORBIDITY; CROSS-SECTIONAL STUDY; DEMOGRAPHY; DEPRESSION; DIABETES MELLITUS; DIABETIC NEUROPATHY; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE SEVERITY; DRUG USE; EMPLOYMENT STATUS; FEMALE; GENERAL ASPECTS OF DISEASE; GENERAL PRACTITIONER; HEALTH CARE COST; HEALTH CARE UTILIZATION; HEALTH STATUS; HELP SEEKING BEHAVIOR; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PAIN ASSESSMENT; PRESCRIPTION; PRODUCTIVITY; QUALITY OF LIFE; REVIEW; SELF REPORT; SLEEP DISORDER; SLEEP QUALITY; TRANSCUTANEOUS NERVE STIMULATION; UNITED STATES; VALIDATION PROCESS; WORK DISABILITY;

EID: 84873689387     PISSN: 11787007     EISSN: None     Source Type: Journal    
DOI: 10.2147/DMSO.S37415     Document Type: Review

References (35)

1. Gore M, Brandenburg NA, Dukes E, Hoffman DL, Tai K-S, Stacey B. Pain severity in diabetic peripheral neuropathy is associated with patient functioning, symptom levels of anxiety and depression, and sleep. J Pain Symptom Manage. 2005;30(4):374-385.
2. Sadosky A, McDermott AM, Brandenburg NA, Strauss M. A Review of the epidemiology of painful diabetic peripheral neuropathy, postherpetic neuralgia, and less commonly studied neuropathic pain conditions. Pain Practice. 2008;8(1):45-56.
3. Gregg EW, Sorlie P, Paulose-Ram R, et al. Prevalence of lower-extremity disease in the US adult population 40 years of age with and without diabetes: 1999-2000 national health and nutrition examination survey. Diabetes Care. 2004;27:1591-1597.
4. Galluzzi KE. Management of neuropathic pain. J Am Osteopath Assoc. 2005;105 Suppl 4:S12-S19.
5. Taylor-Stokes G, Pike J, Sadosky A, Chandran A, Toelle T. Association of patient-rated severity with other outcomes in patients with painful diabetic peripheral neuropathy. Diabetes Metab Syndr Obes. 2011;4: 401-408.
6. Baron R, Tölle TR, Gockel U, Brosz M, Freynhagen R. A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: Differences in demographic data and sensory symptoms. Pain. 2009;146(1):34-40.
7. Tolle T, Xu X, Sadosky AB. Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns. J Diabetes Complications. 2006;20(1):26-33.
8. Gore M, Brandenburg NA, Hoffman DL, Tai KS, Stacey B. Burden of illness in painful diabetic peripheral neuropathy: the patients' perspectives. J Pain. 2006;7(12):892-900.
9. Jensen MP, Chodroff MJ, Dworkin RH. The impact of neuropathic pain on health-related quality of life. Neurology. 2007;68(15): 1178-1182.
10. daCosta DiBonaventura M, Cappelleri JC, Joshi AV. A longitudinal assessment of painful diabetic peripheral neuropathy on health status, productivity, and health care utilization and cost. Pain Med. 2011;12(1): 118-126.
11. Dworkin RH, Panarites CJ, Armstrong EP, Malone DC, Pham SV. Health care utilization in people with postherpetic neuralgia and painful diabetic peripheral neuropathy. J Am Geriatr Soc. 2011;59(5): 827-836.
12. Ritzwoller DP, Ellis JL, Korner EJ, Hartsfield CL, Sadosky A. Comorbidities, health care service utilization and costs for patients identified with painful DPN in a managed-care setting. Curr Med Res Opin. 2009;25(6):1319-1328.
13. Ware JE, Kosinski M, Turner-Bowker DM, Sundaram M, Gandek B, Maruish ME. User's Manual for the SF-12v2 Health Survey Second Edition: Lincoln, RI: QualityMetric Incorporated; 2009.
14. Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337-343.
15. Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore. 1994;23(2):129-138.
16. Hays RD, Martin SA, Sesti AM, Spritzer KL. Psychometric properties of the Medical Outcomes Study Sleep measure. Sleep Med. 2005;6(1): 41-44.
17. Snaith RP, Zigmond AS. The Hospital Anxiety and Depression scale. Br Med J (Clin Res Ed). 1986;292(6516):344.
18. Zigmond AS, Snaith RP. The Hospital Anxiety And Depression scale. Acta Psychiatr Scand. 1983;67(6):361-370.
19. Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993;4(5):353-365.
20. Cleeland C. The Brief Pain Inventory User Guide. 2009. Available from: http://www.mdanderson.org/education-and-research/departments-programs-and-labs/departments-and-divisions/symptom-research/symptom-assessment-tools/BPI_UserGuide.pdf. Accessed September 15, 2011.
21. Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220-233.
22. Viala-Danten M, Martin S, Guillemin I, Hays RD. Evaluation of the reliability and validity of the Medical Outcomes Study sleep scale in patients with painful diabetic peripheral neuropathy during an international clinical trial. Health Qual Life Outcomes. 2008;6:113.
23. Reilly Associates. WPAI Scoring. Available from: http://www.reillyassociates.net/WPAI_Scoring.html. Accessed December 10, 2012.
24. Pharmacy Benefit Management Institute. Pharmacy and drug manufacturer reimbursement. Available from: http://www.benefitdesignreport.com/PharmacyReimbursement/tabid/66/Default.aspx. Accessed November 26, 2012.
25. US Department of Labor. Bureau of Labor Statistics. Available from: http://www.bls.gov/oes/current/oes_nat.htm#00-0000. Accessed November 26, 2012.
26. Lofland JH, Pizzi L, Frick KD. A review of health-related workplace productivity loss instruments. Pharmacoeconomics. 2004;22(3): 165-184.
27. Social Security Administration. Research, Statistics and Policy Analysis. Available from: http://www.ssa.gov/policy/docs/quickfacts/stat_snap shot/. Accessed November 26, 2012.
28. Zelman DC, Dukes E, Brandenburg N, Bostrom A, Gore M. Classification of mild, moderate and severe pain due to diabetic peripheral neuropathy based on levels of functional disability. J Pain. 2004;5 Suppl 1:114.
29. Zelman DC, Dukes E, Brandenburg N, Bostrom A, Gore M. Identification of cut-points for mild, moderate and severe pain due to diabetic peripheral neuropathy. Pain. 2005;115(1-2):29-36.
30. McDermott AM, Toelle TR, Rowbotham DJ, Schaefer CP, Dukes EM. The burden of neuropathic pain: results from a cross-sectional survey. Eur J Pain. 2006;10(2):127-135.
31. O'Connor AB. Neuropathic pain: quality-of-life impact, costs and cost effectiveness of therapy. Pharmacoeconomics. 2009;27(2):95-112.
32. Zelman DC, Brandenburg NA, Gore M. Sleep impairment in patients with painful diabetic peripheral neuropathy. Clin J Pain. 2006;22(8): 681-685.
33. Ware JE, Kosinski M, Turner-Bowker DM, Sundaram M, Gandek B, Maruish ME. User's Manual for the SF-12v2 Health Survey Second Edition. Lincoln, RI: QualityMetric Incorporated; 2009.
34. Luo N JJ, Shaw JW, Feeny D, Coons SJ. Self-reported health status of the general adult US population as assessed by the EQ-5D and Health Utilities Index. Med Care. 2005;43(11):1078-1086.
35. Cruccu G, Anand P, Attal N, et al. EFNS guidelines on neuropathic pain assessment. Eur J Neurol. 2004;11(3):153-162.