Integrating muscle cell biochemistry and whole-body physiology in humans: 31P-MRS data from the InSight trial

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Edwards, Lindsay M ^a,c,g   Kemp, Graham J ^b   Dwyer, Renee M ^c   Walls, Justin T ^c   Fuller, Huddy ^c   Smith, Steven R ^d,e   Earnest, Conrad P ^f  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF TASMANIA   (Australia)

^d BURNHAM INSTITUTE   (United States)

^e FLORIDA HOSPITAL   (United States)

^f Pennington Biomedical Research Institute   (United States)

^g KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE PHOSPHATE; PHOSPHORUS;

ADULT; ARTICLE; CHEMISTRY; COHORT ANALYSIS; ENERGY METABOLISM; FEMALE; HUMAN; LONGITUDINAL STUDY; MALE; METABOLISM; MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN CONSUMPTION; PH; PRINCIPAL COMPONENT ANALYSIS; SCINTISCANNING; SKELETAL MUSCLE;

ADULT; COHORT STUDIES; ENERGY METABOLISM; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MITOCHONDRIA; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; PHOSPHOCREATINE; PHOSPHORUS ISOTOPES; PRINCIPAL COMPONENT ANALYSIS;

MLCS; MLOWN;

EID: 84873674911     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01182     Document Type: Article

References (34)

1. Kemp, G. J. & Radda, G. K. Quantitative interpretation of bioenergetic data from 31P and 1H magnetic resonance spectroscopic studies of skeletal muscle: an analytical review. Magn Reson Q 10, 43-63 (1994).
2. Coyle, E. F., Sidossis, L. S., Horowitz, J. F. & Beltz, J. D. Cycling efficiency is related to the percentage of type I muscle fibers. Med Sci Sports Exerc 24, 782-788 (1992).
3. Livingstone, M. B. & Black, A. E. Markers of the validity of reported energy intake. J Nutr 133 Suppl 3, 895S-920S (2003). (Pubitemid 36262798)
4. Schoeller, D. A. How accurate is self-reported dietary energy intake? Nutr Rev 48, 373-379 (1990). (Pubitemid 20351398)
5. Schulz, L. O., Alger, S., Harper, I., Wilmore, J. H. & Ravussin, E. Energy expenditure of elite female runners measured by respiratory chamber and doubly labeled water. J Appl Physiol 72, 23-28 (1992).
6. Forbes, G. B. in Human body composition. Growth, aging, nutrition, and activity. 209-247 (Springer-Verlag, 1987).
7. Forbes, G. B., Brown, M. R.,Welle, S. L. & Lipinski, B. A. Deliberate overfeeding in women and men: energy cost and composition of the weight gain. Br J Nutr 56, 1-9 (1986). (Pubitemid 16034183)
8. Pullar, J. D. &Webster, A. J. The energy cost of fat and protein deposition in the rat. Br J Nutr 37, 355-363 (1977). (Pubitemid 8100112)
9. Spady, D. W., Payne, P. R., Picou, D. & Waterlow, J. C. Energy balance during recovery from malnutrition. Am J Clin Nutr 29, 1073-1088 (1976).
10. Tataranni, P. A. et al. Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure. Int J Obes Relat Metab Disord 27, 1578-1583 (2003). (Pubitemid 38019175)
11. de Jonge, L. et al. Validation study of energy expenditure and intake during calorie restriction using doubly labeled water and changes in body composition. Am J Clin Nutr 85, 73-79 (2007). (Pubitemid 46067618)
12. Jubrias, S. A., Crowther, G. J., Shankland, E. G., Gronka, R. K. & Conley, K. E. Vol. 553, 589-599 (2003).
13. Naressi, A., Couturier, C., Castang, I., de Beer, R. & Graveron-Demilly, D. Javabased graphical user interface for MRUI, a software package for quantitation of in vivo/medical magnetic resonance spectroscopy signals. Comput Biol Med 31, 269-286 (2001). (Pubitemid 32378728)
14. Vanhamme, L., van den Boogaart, A. & Van Huffel, S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 129, 35-43 (1997). (Pubitemid 127454051)
15. Kemp, G. J., Meyerspeer, M. & Moser, E. Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review. NMR Biomed 20, 555-565 (2007). (Pubitemid 47496897)
16. Golding, E. M., Teague, W. E.&Dobson,G. P. Adjustment ofK' to varying pH and pMg for the creatine kinase, adenylate kinase and ATP hydrolysis equilibria permitting quantitative bioenergetic assessment. J Exp Biol 198, 1775-1782 (1995).
17. Braun, M. Differential Equations and their Applications. 4 edn, (Springer, 1941).
18. Amara, C. E. et al.Mitochondrial function in vivo: Spectroscopy provides window on cellular energetics. Methods 46, 312-318 (2008).
19. Jeneson, J. A. L., Wiseman, R. W., Westerhoff, H. V. & Kushmerick, M. J. The signal transduction function for oxidative phosphorylationiIs at least second order in ADP. J. Biol. Chem. 271, 27995-27998 (1996). (Pubitemid 26374600)
20. Rodgers, J. L. & Nicewander, W. A. Thirteen ways to look at the correlation coefficient. The American Statistician 42, 59-66 (1988).
21. Larson-Meyer, D. E., Newcomer, B. R., Hunter, G. R., Hetherington, H. P. & Weinsier, R. L. 31P MRS measurement of mitochondrial function in skeletal muscle: reliability, force-level sensitivity and relation to whole body maximal oxygen uptake. NMR Biomed 13, 14-27 (2000). (Pubitemid 30136998)
22. McCully, K. K., Fielding, R. A., Evans, W. J., Leigh, J. S. & Posner, J. D. Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. Journal of Applied Physiology 75, 813-819 (1993). (Pubitemid 23260225)
23. Conley, K. E. et al. Ageing, muscle properties and maximal O(2) uptake rate in humans. J Physiol 526 Pt 1, 211-217 (2000). (Pubitemid 30456103)
24. Wyss, M. &Wallimann, T. Creatinemetabolism and the consequences of creatine depletion in muscle. Mol Cell Biochem 133-134, 51-66 (1994). (Pubitemid 24276825)
25. Madhu, B., Lagerwall, K. & Soussi, B. Phosphorus metabolites in different muscles of the rat leg by 31P image-selected in vivo spectroscopy. NMRBiomed 9, 327-332 (1996). (Pubitemid 27249499)
26. Takahashi, H. et al. Relationships between fiber composition and NMR measurements in human skeletal muscle. NMR Biomed 9, 8-12 (1996). (Pubitemid 26310153)
27. Wasserman, K., Hansen, J. E., Sue, D. Y., Stringer, W. W. & Whipp, B. J. in Principles of Exercise Testing and Interpretation (Lipincott Williams and Wilkins, 2005).
28. Mallory, L. A. et al. Influence of peak VO2 and muscle fiber type on the efficiency of moderate exercise. Med Sci Sports Exerc 34, 1279-1287 (2002). (Pubitemid 34840026)
29. Hunter, G. R. et al. Inverse relationship between exercise economy and oxidative capacity in muscle. Eur J Appl Physiol 94, 558-568 (2005). (Pubitemid 41136055)
30. Lucia, A., Hoyos, J., Perez, M., Santalla, A. & Chicharro, J. L. Inverse relationship between VO2max and economy/efficiency in world-class cyclists. Med Sci Sports Exerc 34, 2079-2084 (2002). (Pubitemid 35440433)
31. Edwards, L. M. et al. Uncoupling protein 3 inversely correlates with resting metabolic rate in fit, young men. Proc Physiol Soc 11, C49 (2008).
32. Vaughan-Jones, R. D., Spitzer, K. W. & Swietach, P. Intracellular pH regulation in heart. J Mol Cell Cardiol 46, 318-331 (2009).
33. Kampert, J. B., Blair, S. N., Barlow, C. E.& Kohl, H. W., 3rd. Physical activity, physical fitness, and all-cause and cancer mortality: a prospective study of men and women. Ann Epidemiol 6, 452-457 (1996). (Pubitemid 26372534)
34. Mogensen, M., Bagger, M., Pedersen, P. K., Fernstrom, M. & Sahlin, K. Cycling efficiency in humans is related to low UCP3 content and to type I fibres but not to mitochondrial efficiency. J Physiol 571, 669-681 (2006). (Pubitemid 43329555)