31P MRS measurement of mitochondrial function in skeletal muscle: Reliability, force-level sensitivity and relation to whole body maximal oxygen uptake

NMR in Biomedicine

Volumn 13, Issue 1, 2000, Pages 14-27

  Larson Meyer, D Enette ^a   Newcomer, Bradley R ^a   Hunter, Gary R ^a   Hetherington, Hoby P ^b   Weinsier, Roland L ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Methodology; Muscle metabolism; Oxidative capacity; Reproducibility; Validity

Indexed keywords

CREATINE PHOSPHATE; OXYGEN; ADENOSINE DIPHOSPHATE; BIOLOGICAL MARKER; PHOSPHORUS;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; ISOMETRIC EXERCISE; MUSCLE METABOLISM; MUSCLE MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; SKELETAL MUSCLE; MIDDLE AGED; MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PHYSIOLOGY;

ADENOSINE DIPHOSPHATE; ADULT; BIOLOGICAL MARKERS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; MITOCHONDRIA; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; PHOSPHOCREATINE; PHOSPHORUS ISOTOPES; REPRODUCIBILITY OF RESULTS;

EID: 0033621867     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(200002)13:1<14::AID-NBM605>3.0.CO;2-0     Document Type: Article

References (45)

1. Bassett, D. R. Skeletal muscle characteristics: relationship to cardiovascular risk factors. Med. Sci. Sport Exerc. 26, 957-966 (1994).
2. Henriksson, J. and Reitman, J. S. Time course of changes in human skeletal muscle succinate dehydrogenase and cytochrome oxidase activities and maximal oxygen uptake with physical activity and inactivity. Acta Physiol. Scand. 99, 91-97 (1977).
3. Holloszy, J. O. and Coyle, E. F. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J. Appl. Physiol. 56, 831-838 (1984).
4. Costill, D. L., Fink, W. J. and Pollock, M. L. Muscle fiber composition and enzyme activities of elite distance runners. Med. Sci. Sport Exerc. 8, 96-100 (1976).
5. Costill, D. L., Daniels, J., Evans, W., Fink, W., Krahenbuhl, G. and Saltin, B. Skeletal muscle enzymes and fiber composition in male and female track athletes. J. Appl. Physiol. 40, 149-154 (1976).
6. McCully, K. K., Fielding, R. A., Evans, W. J., Leigh, J. S. and Posner, J. D. Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. J. Appl. Physiol. 75, 813-819 (1993).
7. Hickey, M. S., Weidner, M. D., Gavigan, K. E., Zheng, D., Tyndall, G. L. and Houmard, J. A. The insulin action-fiber type relationship in humans is muscle group specific. Am. J. Physiol. 269, E150-E154 (1995).
8. Simoneau, J. A. and Bouchard, C. Skeletal muscle metabolism and body fat content in men and women. Obes. Res. 3, 23-29 (1995).
9. 2 and phosphorylcreatine level. J. Gen. Physiol. 86, 135-165 (1985).
10. Harris, R. C., Edwards, R. H. T., Hultman, E., Nordesjo, L.-O., Nylind, B. and Sahlin, K. The time course of phosphorylcreatine resynthesis during recovery of the quadriceps muscle in man. Pfluegers Arch. 367, 137-142 (1976).
11. 31P nuclear magnetic resonance study. Mol. Biol. Med. 1, 77-94 (1983).
12. 31P MRS. Magn. Reson. Med. 32, 1-10 (1994).
13. Boska, M. D., Nelson, J. A., Sripathi, N. and Welch, L. M. A. Initial 10 seconds of PCr recovery is a very sensitive indicator of changes in oxidative metabolism. Proceedings, International Society of Magnetic Resonance in Medicine, 1312 (1997).
14. Newcomer, B. R. and Boska, M. Adenosine triphosphate production rates, metabolic economy calculations, pH, phosphomonoesters, phosphodiesters, and force output during short-duration maximal isometric plantar flexion exercises and repeated maximal isometric plantar flexion exercises. Muscle Nerve 20, 336-346 (1997).
15. 31P MRS study. NMR Biomed. 9, 165-172 (1996).
16. 31P NMR. Magn. Reson. Med. 1, 307-315 (1984).
17. Bendahan, D., Confort-Gouny, S., Kozak-Reiss, G. and Cozzone, P. J. Heterogeneity of metabolic response to muscular exercise in humans. FEBS 272, 155-158 (1990).
18. 31P-MRS. J. Appl. Physiol. 78, 2218-2227 (1995).
19. 31P magnetic resonance spectroscopy. Can. J. Physiol. Pharmac. 70, 1353-1359 (1992).
20. Taylor, D. J., Kemp, G. J. and Radda, G. K. Bioenergetics of skeletal muscle in mitochondrial myopathy. J. Neurol. Sci. 127, 198-206 (1994).
21. Meyer, R. A. A linear model of muscle respiration explains monoexponential phosphocreatine changes. Am. J. Physiol. 254, C548-C553 (1988).
22. Takahashi, H., Inaki, M., Fujimoto, K., Katsuta, S., Anno, I., Niitsu, M. and Itai, Y. Control of the rate of phosphocreatine resynthesis after exercise in trained and untrained human quadriceps muscles. Eur. J. Appl. Phys. 71, 396-404 (1995).
23. Paganini, A. T., Foley, J. M. and Meyer, R. A. Linear dependence of muscle phosphocreatine kinetics on oxidative capacity. Am. J. Physiol. 272, CS01-C510 (1997).
24. Hansen, N. J., Lohman, T. G., Going, S. B., Hall, M. C., Pamenter, R. W., Bare, L. A., Boyden, T. W. and Houtkooper, L. B. Prediction of body composition in premenopausal females from dual-energy X-ray absorptiometry. J. Appl. Physiol. 75, 1637-1641 (1993).
25. SensorMedics Corporation. Operators Manual. SensorMedics Corporation, Yorba Linda, CA, 1992.
26. Vaughan, J. T., Hetherington, H. P. and Pohost, G. M. A toroidal cavity coil for high frequency clinical NMR. Proceedings of the Society of Magnetic Resonance, 996 (1995).
27. Taylor, D. J., Styles, P., Matthews, P. M., Arnold, D. A., Gadian, D. G., Bore, P. and Radda, G. K. Energetics of human muscle: exercise-induced ATP depletion. Magn. Reson. Med. 3, 44-54 (1986).
28. eq of the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions. J. Biol. Chem. 254, 6528-6537 (1979).
29. Chasiotis, D., Bergstrom, M. and Hultman, E. ATP utilization and force during intermittent and continuous muscle contractions. J. Appl. Physiol. 63, 167-174 (1987).
30. Meyer, R. A., Brown, T. R. and Kushmerick, M. J. Phosphorus nuclear magnetic resonance of fast-and slow-twitch muscle. Am. J. Physiol. 248, C279-C287 (1985).
31. Spriet, L. L., Soderlund, L., Bergstrom, M. and Hultman, E. Anaerobic energy release in skeletal muscle during electrical stimulation in men. J. Appl. Physiol. 62, 611-615 (1987).
32. Miller, R. G., Carson, P. J., Moussavi, R. S., Green, A., Baker, A., Boska, M. D. and Weiner, M. W. Factors which influence alterations of phosphates and pH in exercising human skeletal muscle: measurement error, reproducibility, and effects of fasting, carbohydrate loading, and metabolic acidosis. Muscle & Nerve 18, 60-67 (1995).
33. McCully, K., Strear, C., Prammer, M. and Leigh, J. Post-exercise recovery of phosphocreatine as an index of oxidative capacity (Abstract) FASEB J. 4, A1212 (1990).
34. Hultman, E., Sjoholm, H., Sahlin, K. and Edostrom, L. Glycolytic and oxidative energy metabolism and contraction characteristics of intact human muscle. Ciba Found. Symp. 82, 19-40 (1981).
35. Kent-Braun, J. A., Miller, R. G. and Weiner, M. W. Magnetic resonance spectroscopy studies of human muscle. Radiol. Clin. N. Am. 32, 313-335 (1994).
36. Quistorff, B., Johansen, L. and Sahlin, K. Absence of phosphocreatine resynthesis in human calf muscle during ischaemic recovery. Biochem. J. 291, 681-686 (1992).
37. 31P-MR spectroscopy study. Biochem. Biophys. Res. Commun. 176, 1204-1209 (1991).
38. Gadian, D. G., Radda, G. K., Brown, T. R., Chance, E. M., Dawson, M. J. and Wilkie, D. R. The activity of creatine kinase in frog skeletal muscle studied by saturation-transfer nuclear magnetic resonance. Biochem. J. 194, 215-228 (1981).
39. Chance, B., Leigh, J. S., Clark, B. J., Maris, J., Kent, J., Nioka, S. and Smith, D. Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function. Proc. Natl. Acad. Sci. USA 82, 8384-8388 (1985).
40. Kemp, G. J., Taylor, D. J. and Radda, G. K. Control of phosphocreatine resynthesis during recovery from exercise in human skeletal muscle. NMR Biomed. 6, 66-72 (1993).
41. Blei, M. L., Conley, K. E. and Kushmerick, M. J. Separate measures of ATP utilization and recovery in human skeletal muscle. J. Phyiol. 465, 203-222 (1993).
42. Chance, B. and Conrad, H. Acid-linked functions of intermediates in oxidative phosphorylation. II. Experimental studies of the effect of pH upon respiratory, phosphorylative, and transfer activities of liver and heart mitochondria. J. Biol. Chem. 234, 1568-1570 (1959).
43. Chance, B. J., Leigh, J. S., Kent, J., McCully, K., Nioka, S., Clark, B. J., Maris, J. M. and Graham, T. Multiple controls of oxidative metabolism in living tissues as studied by phosphorus magnetic resonance. Proc. Natl Acad Sci. USA 83, 9458-9462 (1986).
44. Connett, R. J. Analysis of metabolic central: new insights using scaled creatine kinase model. Am. J. Physiol. 254, R949-R959 (1988).
45. 31P MRS. The role of pH in the evaluation of phosphocreatine and inorganic phosphate recoveries from exercise. NMR Biomed. 6, 248-253 (1993).