Diagnosis, treatment, and outcome of giant-cell myocarditis in the era of combined immunosuppression

Circulation: Heart Failure

Volumn 6, Issue 1, 2013, Pages 15-22

  Kandolin, Riina ^a   Lehtonen, Jukka ^a,c   Salmenkivi, Kaisa ^b   Räisänen Sokolowski, Anne ^b   Lommi, Jyri ^a   Kupari, Markku ^a  

^a Division of Cardiology   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Cardiac transplant; Endomyocardial biopsy; Myocarditis

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; IMMUNOGLOBULIN; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISONE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEFIBRILLATOR; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; GIANT CELL MYOCARDITIS; HEART FIBRILLATION; HEART MUSCLE BIOPSY; HEART VENTRICLE TACHYCARDIA; HISTOPATHOLOGY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MALE; MEDICAL HISTORY; MYOCARDITIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REMISSION; TREATMENT OUTCOME;

ADULT; AGED; BIOPSY; DIAGNOSIS, DIFFERENTIAL; DRUG THERAPY, COMBINATION; FINLAND; GIANT CELLS; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; MYOCARDITIS; MYOCARDIUM; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84873646567     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.112.969261     Document Type: Article

References (12)

1. Cooper LT Jr, Berry GJ, Shabetai R. Idiopathic giant-cell myocarditis-natural history and treatment. Multicenter Giant Cell Myocarditis Study Group Investigators. N Engl J Med. 1997;336:1860-1866.
2. Rosenstein ED, Zucker MJ, Kramer N. Giant cell myocarditis: Most fatal of autoimmune diseases. Semin Arthritis Rheum. 2000;30:1-16.
3. Okura Y, Dec GW, Hare JM, Kodama M, Berry GJ, Tazelaar HD, Bailey KR, Cooper LT. A clinical and histopathologic comparison of cardiac sarcoidosis and idiopathic giant cell myocarditis. J Am Coll Cardiol. 2003;41:322-329.
4. Menghini VV, Savcenko V, Olson LJ, Tazelaar HD, Dec GW, Kao A, Cooper LT Jr. Combined immunosuppression for the treatment of idiopathic giant cell myocarditis. Mayo Clin Proc. 1999;74:1221-1226.
5. Cooper LT Jr, Hare JM, Tazelaar HD, Edwards WD, Starling RC, Deng MC, Menon S, Mullen GM, Jaski B, Bailey KR, Cunningham MW, Dec GW; Giant Cell Myocarditis Treatment Trial Investigators. Usefulness of immunosuppression for giant cell myocarditis. Am J Cardiol. 2008;102:1535-1539.
6. Granér M, Lommi J, Kupari M, Räisänen-Sokolowski A, Toivonen L. Multiple forms of sustained monomorphic ventricular tachycardia as common presentation in giant-cell myocarditis. Heart. 2007;93:119-121.
7. Kandolin R, Lehtonen J, Graner M, Schildt J, Salmenkivi K, Kivistö SM, Kupari M. Diagnosing isolated cardiac sarcoidosis. J Intern Med. 2011;270:461-468.
8. Kytö V, Saukko P, Lignitz E, Schwesinger G, Henn V, Saraste A, Voipio-Pulkki LM. Diagnosis and presentation of fatal myocarditis. Hum Pathol. 2005;36:1003-1007.
9. Kandolin R, Lehtonen J, Kupari M. Cardiac sarcoidosis and giant cell myocarditis as causes of atrioventricular block in young and middle-aged adults. Circ Arrhythm Electrophysiol. 2011;4:303-309.
10. Ren H, Poston RS Jr, Hruban RH, Baumgartner WA, Baughman KL, Hutchins GM. Long survival with giant cell myocarditis. Mod Pathol. 1993;6:402-407.
11. Shields RC, Tazelaar HD, Berry GJ, Cooper LT Jr. The role of right ventricular endomyocardial biopsy for idiopathic giant cell myocarditis. J Card Fail. 2002;8:74-78.
12. Banba K, Kusano KF, Nakamura K, Morita H, Ogawa A, Ohtsuka F, Ogo KO, Nishii N, Watanabe A, Nagase S, Sakuragi S, Ohe T. Relationship between arrhythmogenesis and disease activity in cardiac sarcoidosis. Heart Rhythm. 2007;4:1292-1299.