Giant cell myocarditis: Most fatal of autoimmune diseases

Seminars in Arthritis and Rheumatism

Volumn 30, Issue 1, 2000, Pages 1-16

  Rosenstein, Elliot D ^a,b   Zucker, Mark J ^a,b   Kramer, Neil ^a,b  

^a SAINT BARNABAS MEDICAL CENTER   (United States)

^b NEWARK BETH ISRAEL MEDICAL CENTER   (United States)

Author keywords

Autoimmunity; Giant cells; Immunosuppressive therapy; Myocarditis

Indexed keywords

15 DEOXYSPERGUALIN; ACETYLSALICYLIC ACID; ANTIARRHYTHMIC AGENT; ANTICOAGULANT AGENT; AUTOANTIBODY; AZATHIOPRINE; CD4 ANTIGEN; CD8 ANTIGEN; CREATINE KINASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTOKINE; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HEART ENZYME; LUPUS ANTICOAGULANT; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; MYOSIN HEAVY CHAIN; NITRATE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OKT 3; PREDNISOLONE; PREDNISONE; TACROLIMUS; TROPONIN I; UNINDEXED DRUG; VASODILATOR AGENT;

AUTOIMMUNE DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE COURSE; GIANT CELL; HEART DISEASE; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MULTICENTER STUDY; MYOCARDITIS; NONHUMAN; PERICARDITIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; THROMBUS;

EID: 0033903959     PISSN: 00490172     EISSN: None     Source Type: Journal    
DOI: 10.1053/sarh.2000.8367     Document Type: Article

References (119)

1. Giant cell versus granulomatous myocarditis
2. Isolated myocarditis
3. Twenty year autopsy statistics of myocarditis incidence in Japan
4. Animal models of human disease: Autoimmunity in myocarditis: Relevance of animal models
5. Giant cell myocarditis
6. Myocarditis: Unresolved issues in diagnosis and treatment
7. Inflammatory myocardial diseases and cardiomyopathies
8. Myocarditis: A histopathologic definition and classification
9. Distinct forms of myocarditis
10. Giant cell myocarditis: Light and electron microscopic study
11. Giant cell myocarditis
12. Idiopathic giant-cell myocarditis: Natural history and treatment
13. Giant cell myocarditis in a newborn with congenital herpes simplex virus (HSV) infection: An immunohistochemical study on the origin of the giant cells
14. Giant cell versus lymphocytic myocarditis: A comparison of their clinical features and long-term outcomes
15. Clinicopathologic description of myocarditis
16. Long survival with giant cell myocarditis
17. Idiopathic giant cell myocarditis
18. Granulomatous myocarditis and myositis associated with thymoma
19. Bilateral orbital involvement in fatal giant cell polymyositis
20. Giant-cell myocarditis with multiple organ involvement
21. Orbital myositis and giant cell myositis
22. Gallium-67 imaging in patients with dilated cardiomyopathy and biopsy-proven myocarditis
23. Scintigraphic detection of inflammatory heart disease
24. Usefulness of magnetic resonance imaging for diagnosis of acute myocarditis in infants and children, and comparison with endomyocardial biopsy
25. Giant cell myocarditis
26. Idiopathic giant cell myocarditis: A distinctive clinico-pathological entity
27. Acute idiopathic interstitial myocarditis: Case report with special reference to morphological characteristics of giant cells
28. Giant cell myocarditis
29. Giant cell myocarditis: Monocytic immunophenotype of giant cells in a case associated with ulcerative colitis
30. Phenotypic analysis of infiltrating cells in human myocarditis: An immunohistochemical study in paraffin-embedded tissue
31. Giant cell myocarditis associated with lymphoma: An immunocytochemical study
32. Characteristics of giant cells and factors related to the formation of giant cells in myocarditis
33. Giant cell myocarditis: Evidence for the macrophage origin of the giant cells
34. Severe postcardiac-transplant rejection associated with recurrence of giant cell myocarditis
35. Tuberculosis of the heart: A review
36. Cryptococcus of the heart
37. Myocardial lesions in disseminated coccidioidomycosis
38. Complete heart block due to a solitary gumma
39. Giant cell myocarditis and myositis associated with thymoma and leprosy
40. Giant cell myocarditis: An entity distinct from sarcoidosis characterized by multiphasic myocyte destruction by cytotoxic T cells and histiocytic giant cells
41. Histologic and cytokine response to immunosuppression in giant cell myocarditis
42. Giant cell myocarditis: An autoimmune disease?
43. Myocarditis and endomyocardial biopsy in unexplained heart failure: A diagnosis in search of a disease
44. Antimyosin scintigraphy and immunohistologic analysis of endomyocardial biopsy in patients with clinically suspected myocarditis evidence of myocardial cell damage and inflammation in the absence of histologic signs of myocarditis
45. Insensitivity of right ventricular endomyocardial biopsy in the diagnosis of myocarditis
46. Relation between histological findings on early repeat right ventricular biopsy and ventricular function in patients with myocarditis
47. Diagnosis and classification of myocarditis by endomyocardial biopsy
48. Treatment of acute inflammatory myocardial assisted by endomyocardial biopsy
49. Effects of immunosuppressive therapy in biopsy-proved myocarditis and borderline myocarditis on left ventricular function
50. Lymphocytic myocarditis presenting as unexplained ventricular arrhythmias: Diagnosis with endomyocardial biopsy and response to immunosuppression
51. Heart muscle antibodies in myasthenia gravis
52. Thymoma associated with myocarditis and the LE-cell phenomenon: Report of a case
53. Giant cell myocarditis and myositis: Associated with thymoma and myasthenia gravis
54. Intractable ventricular tachycardia in a patient with giant cell myocarditis, thymoma and myasthenia gravis
55. The heart in myasthenia gravis
56. Pernicious anemia and giant cell myocarditis: New association
57. Cardiac valvular lesions in rheumatoid arthritis
58. Orbital myositis, vitiligo, and giant cell myocarditis
59. Autoantibodies against ventricular myosin in patients with myocarditis and dilated cardiomyopathy
60. Characterization of anti-heart antibodies in mice after infection with coxsackie B3 virus
61. Antibody-mediated enhancement of calcium permeability in cardiac myocytes
62. Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy
63. Cardiac autoantibodies in dilated cardiomyopathy: A pathogenetic role?
64. Laminin distribution and autoantibodies to laminin in dilated cardiomyopathy and myocarditis
65. Autoimmunity and idiopathic dilated cardiomyopathy
66. Diagnostic relevance of humoral and cytotoxic immune reactions in primary and secondary dilated cardiomyopathy
67. Humoral immunity in cardiomyopathy
68. Circulating cardiac-specific autoantibodies as markers of autoimmunity in clinical and biopsy-proven myocarditis
69. A case of giant cell myocarditis with evidence of cardiac autoimmunity
70. A novel experimental model of giant cell myocarditis induced in rats by immunization with cardiac myosin fraction
71. Immunohistochemical characterization of infiltrating mononuclear cells in the rat heart with experimental autoimmune giant cell myocarditis
72. Response of recurrent giant cell myocarditis in a transplanted heart to intensive immunosuppression
73. Autoimmune myocarditis: A murine model
74. In situ immune autoradiographic identification of cells in heart tissues of mice with coxsackie virus B3-induced myocarditis
75. Cellular and molecular mechanisms of murine autoimmune myocarditis
76. T cells in cardiac myosin-induced myocarditis
77. The role of T cells in myosin-induced autoimmune myocarditis
78. Cardiac myosin-induced myocarditis: Heart autoantibodies are not involved in the induction of the disease
79. Effects of cyclosporine, prednisolone, and aspirin on rat autoimmune giant cell myocarditis
80. FK 506 therapy of experimental autoimmune myocarditis after onset of the disease
81. Effects of 15-deoxyspergualin on experimental autoimmune giant cell myocarditis of the rat
82. Anti-αβ T cell receptor antibody prevents the progression of experimental autoimmune myocarditis
83. The effects of interleukin-1 on myocardial function and metabolism
84. Viral myocarditis leading to cardiomyopathy: Do cytokines contribute to pathogenesis?
85. Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis
86. Cardiac myosin induces myocarditis in genetically predisposed mice
87. Congestive cardiomyopathy in nonspecific aortoarteritis
88. Cardiac involvement in nonspecific aortoarteritis (Takayasu's arteritis)
89. Myocardial involvement and its response to immunosuppressive therapy in nonspecific aortoarteritis (Takayasu's disease): A study by endomyocardial biopsy
90. Idiopathic pan-aortitis, supra-aortic arteritis, granulomatous myocarditis, and pericarditis: A cause of pulseless disease and possibly left ventricular aneurysm in the African
91. Sub-clinical systemic lupus erythematosus presenting with acute myocarditis
92. Polymyositis: Its presentation, morbidity, and mortality
93. Adult onset polymyositis/dermatomyositis: An analysis of clinical and laboratory features and survival in 76 patients with a review of the literature
94. Two cases of polymyositis with cardiac involvement
95. A new approach to the classification of idiopathic inflammatory myopathy: Myositis-specific autoantibodies define useful homogeneous patient groups
96. Cardiac sarcoid: A clinicopathologic study of 84 unselected patients with systemic sarcoidosis
97. Clinical course of cardiac sarcoidosis
98. Fatal myocardial sarcoidosis
99. Sarcoid heart disease
100. Clinicopathological study of fatal myocardial sarcoidosis
101. Sarcoidosis of the heart: A clinicopathological study of 35 necropsy patients (group 1) and review of 78 previously described autopsy patients (group 2)
102. Myocarditis with multinucleated giant cells detected in biopsy specimens
103. Cardiac sarcoidosis: Diagnostic, prognostic, and therapeutic considerations
104. Isolated myocarditis versus myocardial sarcoidosis: A contribution to the discussion regarding points of resemblance between these and a report of three illustrative cases
105. Cardiac sarcoidosis: Diagnosis with endomyocardial biopsy and treatment with corticosteroids
106. Guidelines for the evaluation and management of heart failure: Report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on Evaluation and Management of Heart Failure)
107. Is immunosuppressive treatment an option for myocarditis?
108. Management strategies in viral myocarditis
109. Immunosuppressive therapy for myocarditis and dilated cardiomyopathy
110. A clinical trial of immunosuppressive therapy for myocarditis
111. Giant cell myocarditis: Dramatic haemodynamic and histologic improvement with immunosuppressive therapy
112. Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis
113. Combined immunosuppression for the treatment of idiopathic giant cell myocarditis
114. Idiopathic giant cell myocarditis after autologous hematopoietic stem cell transplantation and interleukin-2 immunotherapy: A case report
115. Treatment of serious heart failure by transplantation in giant cell myocarditis diagnosed by endomyocardial biopsy
116. Giant cell myocarditis: First report of disease recurrence in the transplanted heart
117. Giant cell myocarditis in a transplanted heart
118. Autoimmunity in myocarditis: Models and mechanisms
119. Autoimmune myocarditis