Preparation of thrombosis-targeted lipid microbubbles and determination of rabbit carotid artery thrombosis by microbubbles ultrasonogaphy

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 33, Issue 1, 2013, Pages 146-152

  Xu, Wei Ming ^a   Feng, Min ^a   Zhao, Hong Yang ^a   Xie, Ming Xing ^a   Li, Wei Yong ^a   Fu, Rong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

electron microscope; fluorescence detection; magnetic resonance angiography; thrombus; thrombus targeted phospholipid coated microbubbles

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; LIPID;

ANIMAL; ARTICLE; CAROTID ARTERY THROMBOSIS; DRUG FORMULATION; ECHOGRAPHY; FEMALE; IMAGE ENHANCEMENT; MALE; METHODOLOGY; MICROBUBBLE; RABBIT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SYNTHESIS;

ANIMALS; CAROTID ARTERY THROMBOSIS; CONTRAST MEDIA; DRUG COMPOUNDING; FEMALE; IMAGE ENHANCEMENT; LIPIDS; MALE; MICROBUBBLES; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; ULTRASONOGRAPHY;

EID: 84873640488     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-013-1088-9     Document Type: Article

References (13)

1. Bekeredjian R, Chen S, Pan W, et al. Effects of ultrasound-targeted microbubble destruction on cardiac gene expression. Ultrasound Med Biol, 2004,30(4):539-543
2. Xia HM, Gao YH, Bian AN, et al. Evaluation of thrombus-targeted ultrasound contrast agent: Preliminary in vitro study. Zhongguo Chaosheng Yixue Zazhi (Chinese), 2004,20(5):321-323
3. Klibanov AL, Hughes MS, Villanueva FS, et al. Targeting and ultrasound imaging of microbubbles based contrast agents. MAGMA, 1999,8(3):177-184
4. Orth RN, Clark TG, Craighead HG. Avidin-biotin micro-patterning methods for biosensor applications. Biomed Microdevices, 2003,5(1):29-34
5. Wilchek M, Bayer EA, Yamada S, et al. Introduction to avidin-biotin technology. Methods Enzymol, 1990,184(1): 5-13
6. Wilchek M, Bayer EA, Yamada S, et al. Application of avidin-biotin technology: literature survey. Methods Enzymol, 1990,184(1):14-25
7. Chen L, Schechter BA, Arnon RL, et al. Tissue selective affinity targeting using the avidin-biotin system. Drug Dev Res, 2000,50(1):258-271
8. Lu WY, Liu M, Pan J, et al. Preparation of folate-liposome and its delivery into cultured HeLa cells. J Shanghai Med Univ (Chinese), 2000,27(1):4-8
9. Bian AN, Gao YH, Tan KB, et al. Study on immunological properties of human hepatocellular carcinoma-targeted liposome microbubbles. Zhonghua Chaosheng Zazhi (Chinese), 2004,13(9):696-699
10. Li ZS, Zhou JP, Wang LL. Study on the tumor targeting of RGD-PEG-liposomes. China Pharmacy (Chinese), 2003,14(7):393-394
11. Unger E, McCreery TP, Sweitzer RH, et al. In vitro studies of a new thrombus-specific ultrasound contrast agent. Am J Cardiol, 1998,81(12A):58G-61G
12. Unger E, Metzger P, Krupinski E, et al. The use of a thrombus specific ultrasound contrast agent to detect thrombus in arteriovenous fistulae. Invest Radiol, 2000,35(1):86-89
13. Takeuchi M, Ogunyankin K, Pandian NG, et al. Enhanced visualization of intravascular and left atrial appendage thrombus with the use of a thrombus-targeting ultrasonographic contrast agent (MRX-408A1): in vivo experimental echocardiographic studies. J Am Soc Echocardiogr, 1999,12(12):1015-1021