메뉴 건너뛰기




Volumn 5, Issue 6, 2013, Pages 185-189

A nonrandomized, phase II study of sequential irinotecan and flavopiridol in patients with advanced hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

FLAVOPIRIDOL; IRINOTECAN; PROTEIN P53;

EID: 84873633072     PISSN: 19347820     EISSN: 19347987     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (26)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA: Hallmarks of cancer: the next generation. Cell 144:646-674, 2011
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
  • 3
    • 0033551066 scopus 로고    scopus 로고
    • Selective killing of transformed cells by cyclin/cyclin dependent 2 kinase antagonists
    • Chen YN, Sharma SK, Ramsey TM, et al: Selective killing of transformed cells by cyclin/cyclin dependent 2 kinase antagonists. Proc Natl Acad Sci USA 96:4325-4329, 1999
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4325-4329
    • Chen, Y.N.1    Sharma, S.K.2    Ramsey, T.M.3
  • 4
    • 0031736586 scopus 로고    scopus 로고
    • Cell cycle regulators and human hepatocarcinogenesis
    • Hui AM, Makuuchi M, Li X: Cell cycle regulators and human hepatocarcinogenesis. Hepatogastroenterology 45:1635-1642, 1998
    • (1998) Hepatogastroenterology , vol.45 , pp. 1635-1642
    • Hui, A.M.1    Makuuchi, M.2    Li, X.3
  • 5
    • 33845735124 scopus 로고    scopus 로고
    • p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis
    • Matsuda Y, Ichida T: p16 and p27 are functionally correlated during the progress of hepatocarcinogenesis. Med Mol Morphol 39:169-175, 2006
    • (2006) Med Mol Morphol , vol.39 , pp. 169-175
    • Matsuda, Y.1    Ichida, T.2
  • 6
    • 0026452974 scopus 로고
    • Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275
    • Kaur G, Stetler-Stevenson M, Sebers S, et al: Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J Natl Cancer Inst 84:1736-1740, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1736-1740
    • Kaur, G.1    Stetler-Stevenson, M.2    Sebers, S.3
  • 7
    • 3042536038 scopus 로고    scopus 로고
    • Preclinical and clinical development of the cyclin dependent kinase inhibitor flavopiridol
    • Shapiro GI: Preclinical and clinical development of the cyclin dependent kinase inhibitor flavopiridol. Clin Cancer Res 10:4270s-4275s, 2004
    • (2004) Clin Cancer Res , vol.10
    • Shapiro, G.I.1
  • 8
    • 77956637674 scopus 로고    scopus 로고
    • Flavopiridol, the first cyclin dependent kinase inhibitor: Recent advances in combination chemotherapy
    • Wang LM, Ren DM: Flavopiridol, the first cyclin dependent kinase inhibitor: recent advances in combination chemotherapy. Mini Rev Med Chem 10:1058-1070, 2010
    • (2010) Mini Rev Med Chem , vol.10 , pp. 1058-1070
    • Wang, L.M.1    Ren, D.M.2
  • 9
    • 33749076241 scopus 로고    scopus 로고
    • Sequential combinations of flavopiridol and docetaxel inhibit prostate tumors, induce apoptosis, and decrease angiogenesis in the G_/T-15 transgenic mouse model of prostate cancer
    • Reiner T, de las Pozas A, Perez-Stable C: Sequential combinations of flavopiridol and docetaxel inhibit prostate tumors, induce apoptosis, and decrease angiogenesis in the G_/T-15 transgenic mouse model of prostate cancer. Prostate 66:1487-1497, 2006
    • (2006) Prostate , vol.66 , pp. 1487-1497
    • Reiner, T.1    de las Pozas, A.2    Perez-Stable, C.3
  • 10
    • 0034887130 scopus 로고    scopus 로고
    • Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit
    • Jung CP, Motwani MV, Schwartz GK: Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit. Clin Cancer Res 7:2527-2536, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 2527-2536
    • Jung, C.P.1    Motwani, M.V.2    Schwartz, G.K.3
  • 11
    • 0035679234 scopus 로고    scopus 로고
    • Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts
    • Motwani M, Hung C, Sirotnak FM, et al: Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts. Clin Cancer Res 7:4209-4219, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 4209-4219
    • Motwani, M.1    Hung, C.2    Sirotnak, F.M.3
  • 12
    • 0037099517 scopus 로고    scopus 로고
    • Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells
    • Motwani M, Sirotnak FM, She Y, et al: Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells. Cancer Res 62:3950-3955, 2002
    • (2002) Cancer Res , vol.62 , pp. 3950-3955
    • Motwani, M.1    Sirotnak, F.M.2    She, Y.3
  • 13
    • 42049101633 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner
    • Ambrosini G, Seelman SL, Qin LX, et al: The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner. Cancer Res 68:2312-2320, 2008
    • (2008) Cancer Res , vol.68 , pp. 2312-2320
    • Ambrosini, G.1    Seelman, S.L.2    Qin, L.X.3
  • 14
    • 21044432331 scopus 로고    scopus 로고
    • A phase I trial of the sequential combination of irinotecan followed by flavopiridol
    • Shah MA, Kortmansky J, Motwani M, et al: A phase I trial of the sequential combination of irinotecan followed by flavopiridol. Clin Cancer Res 11:3836-3845, 2005
    • (2005) Clin Cancer Res , vol.11 , pp. 3836-3845
    • Shah, M.A.1    Kortmansky, J.2    Motwani, M.3
  • 15
    • 0019365237 scopus 로고
    • Reporting results of cancer treatment
    • Miller AB, Hoogstraten B, Staquet M, et al: Reporting results of cancer treatment. Cancer 47:207-214, 1981
    • (1981) Cancer , vol.47 , pp. 207-214
    • Miller, A.B.1    Hoogstraten, B.2    Staquet, M.3
  • 16
    • 0035174274 scopus 로고    scopus 로고
    • A phase II study of irinotecan in patients with advanced hepatocellular carcinoma
    • O'Reilly EM, Stuart KE, Sanz-Altamira PM, et al: A phase II study of irinotecan in patients with advanced hepatocellular carcinoma. Cancer 91:101-105, 2001
    • (2001) Cancer , vol.91 , pp. 101-105
    • O'Reilly, E.M.1    Stuart, K.E.2    Sanz-Altamira, P.M.3
  • 17
    • 0026524781 scopus 로고
    • Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma
    • Huang CC, Wu MC, Xu GW, et al: Overexpression of the MDR1 gene and P-glycoprotein in human hepatocellular carcinoma. J Natl Cancer Inst 84:262-264, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 262-264
    • Huang, C.C.1    Wu, M.C.2    Xu, G.W.3
  • 18
    • 16044375068 scopus 로고    scopus 로고
    • Concordance between p53 protein overexpression and gene mutation in a large series of human carcinomas
    • Soong R, Robbins PD, Dix BR, et al: Concordance between p53 protein overexpression and gene mutation in a large series of human carcinomas. Hum Pathol 27:1050-1055, 1996
    • (1996) Hum Pathol , vol.27 , pp. 1050-1055
    • Soong, R.1    Robbins, P.D.2    Dix, B.R.3
  • 19
    • 0032940143 scopus 로고    scopus 로고
    • p53 immunoreactivity and single strand conformational polymorphism analysis often fail to predict p53 mutational status
    • Tolbert DM, Noffsinger AE, Miller MA, et al: p53 immunoreactivity and single strand conformational polymorphism analysis often fail to predict p53 mutational status. Mod Pathol 12:54-60, 1999
    • (1999) Mod Pathol , vol.12 , pp. 54-60
    • Tolbert, D.M.1    Noffsinger, A.E.2    Miller, M.A.3
  • 20
    • 79960972539 scopus 로고    scopus 로고
    • Discordances in ER, PR and HER2 receptors after neoadjuvant therapy in breast cancer
    • van de Ven S, Smit VT, Dekker TJ, et al: Discordances in ER, PR and HER2 receptors after neoadjuvant therapy in breast cancer. Cancer Treat Rev 37:422-430, 2011
    • (2011) Cancer Treat Rev , vol.37 , pp. 422-430
    • van de Ven, S.1    Smit, V.T.2    Dekker, T.J.3
  • 21
    • 45949111776 scopus 로고    scopus 로고
    • Changes in tumour biological markers during primary systemic chemotherapy (PST)
    • Neubauer H, Gall C, Vogel U, et al: Changes in tumour biological markers during primary systemic chemotherapy (PST). Anticancer Res 28:1797-1804, 2008
    • (2008) Anticancer Res , vol.28 , pp. 1797-1804
    • Neubauer, H.1    Gall, C.2    Vogel, U.3
  • 22
    • 77956940122 scopus 로고    scopus 로고
    • Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells
    • Jung EU, Yoon JH, Lee YJ, et al: Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells. Cancer Lett 298:9-15, 2010
    • (2010) Cancer Lett , vol.298 , pp. 9-15
    • Jung, E.U.1    Yoon, J.H.2    Lee, Y.J.3
  • 23
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • Llovet JM, di Bisceglie AM, Bruix J, et al: Design and endpoints of clinical trials in hepatocellular carcinoma. Natl Cancer Inst 100:698-711, 2008
    • (2008) Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    di Bisceglie, A.M.2    Bruix, J.3
  • 24
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • Abou-Alfa GK, Schwartz L, Ricci S, et al: Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24:4293-300, 2006
    • (2006) J Clin Oncol , vol.24 , pp. 4293-4300
    • Abou-Alfa, G.K.1    Schwartz, L.2    Ricci, S.3
  • 25
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • Llovet JM, Ricci S, Mazzaferro V, et al: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359:378-390, 2008
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 26
    • 84871019676 scopus 로고    scopus 로고
    • Tivantinib (ARQ197) versus placebo in patients (pts) with hepatocellular carcinoma (HCC) who failed on systemic therapy: Results of a randomized controlled phase II trial (RCT)
    • (abstr 4006)
    • Rimassa L, Porta C, Borbath I, et al: Tivantinib (ARQ197) versus placebo in patients (pts) with hepatocellular carcinoma (HCC) who failed on systemic therapy: results of a randomized controlled phase II trial (RCT). J Clin Oncol 30S:2012 (abstr 4006)
    • (2012) J Clin Oncol , vol.30 S
    • Rimassa, L.1    Porta, C.2    Borbath, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.