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Volumn 27, Issue 2, 2013, Pages 370-376

Flow cytometry and IG/TCR quantitative PCR for minimal residual disease quantitation in acute lymphoblastic leukemia: A French multicenter prospective study on behalf of the FRALLE, EORTC and GRAALL

(26)  Garand, R a   Beldjord, K b,e   Cave H c   Fossat, C d   Arnoux, I d   Asnafi, V e   Bertrand, Y f   Boulland, M L g   Brouzes, C e   Clappier, E c   Delabesse, E h   Fest, T g   Garnache Ottou, F i   Huguet, F h   Jacob, M C j   Kuhlein, E h   Marty Gres S k   Plesa, A l   Robillard, N a   Roussel, M g   more..

f IHOP   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ALLELE; BONE MARROW CELL; CHILD; FLOW CYTOMETRY; GENE REARRANGEMENT; HUMAN; MAJOR CLINICAL STUDY; MINIMAL RESIDUAL DISEASE; MULTICENTER STUDY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY;

EID: 84873570623     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.234     Document Type: Review
Times cited : (69)

References (40)
  • 2
    • 0032572924 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European organization for research and treatment of cancer-childhood leukemia cooperative group
    • Cavé H, Van der Werff ten Bosch J, Suciu S, Guidal C, Waterkeyn C, Otten J et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European organization for research and treatment of cancer-childhood leukemia cooperative group. N Engl J Med 1998; 339: 591-598.
    • (1998) N Engl J Med , vol.339 , pp. 591-598
    • Cavé, H.1    Van Der Werff Ten Bosch, J.2    Suciu, S.3    Guidal, C.4    Waterkeyn, C.5    Otten, J.6
  • 3
    • 0034667685 scopus 로고    scopus 로고
    • Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia
    • Coustan-Smith E, Sancho J, Hancock ML, Boyett JM, Behm FG, Raimondi SC et al. Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia. Blood 2000; 96: 2691-2596.
    • (2000) Blood , vol.96 , pp. 2691-2596
    • Coustan-Smith, E.1    Sancho, J.2    Hancock, M.L.3    Boyett, J.M.4    Behm, F.G.5    Raimondi, S.C.6
  • 4
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factor. A Children's Oncology Group study
    • Borowitz MJ, Devidas M, Hunger SP, Bowman WP, Carroll AJ, Carroll WL et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factor. A Children's Oncology Group study. Blood 2008; 111: 5477-5485.
    • (2008) Blood , vol.111 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3    Bowman, W.P.4    Carroll, A.J.5    Carroll, W.L.6
  • 5
    • 77951441599 scopus 로고    scopus 로고
    • Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: Results in 3184 patients of the AIEOP-BFM ALL 2000 study
    • Conter V, Bartram CR, Valsecchi MG, Schrauder A, Panzer-Grümayer R, Möricke A et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. Blood 2010; 115: 3206-3214.
    • (2010) Blood , vol.115 , pp. 3206-3214
    • Conter, V.1    Bartram, C.R.2    Valsecchi, M.G.3    Schrauder, A.4    Panzer-Grümayer, R.5    Möricke, A.6
  • 6
    • 80052172961 scopus 로고    scopus 로고
    • Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: Results of the AIEOP-BFM-ALL 2000 study
    • Schrappe M, Valsecchi MG, Bartram CR, Schrauder A, Panzer-Grümayer R, Möricke A et al. Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood 2011; 118: 2077-2084.
    • (2011) Blood , vol.118 , pp. 2077-2084
    • Schrappe, M.1    Valsecchi, M.G.2    Bartram, C.R.3    Schrauder, A.4    Panzer-Grümayer, R.5    Möricke, A.6
  • 7
    • 31544467825 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia
    • Brüggemann M, Raff T, Flohr T, Gokbuget N, Nakao M, Droese J et al. Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. Blood 2006; 107: 1116-1123.
    • (2006) Blood , vol.107 , pp. 1116-1123
    • Brüggemann, M.1    Raff, T.2    Flohr, T.3    Gokbuget, N.4    Nakao, M.5    Droese, J.6
  • 8
    • 72249121442 scopus 로고    scopus 로고
    • Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993
    • Patel B, Rai L, Buck G, Richards SM, Mortuza Y, Mitchell W et al. Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993. Br J Haematol 2010; 148: 80-89.
    • (2010) Br J Haematol , vol.148 , pp. 80-89
    • Patel, B.1    Rai, L.2    Buck, G.3    Richards, S.M.4    Mortuza, Y.5    Mitchell, W.6
  • 9
    • 0036051771 scopus 로고    scopus 로고
    • T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis
    • Van der Velden VHJ, Wijkhuijs JM, Jacobs DC, Van Wering ER, Van Dongen JJ. T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis. Leukemia 2002; 16: 1372-1380.
    • (2002) Leukemia , vol.16 , pp. 1372-1380
    • Van Der Velden, V.H.J.1    Wijkhuijs, J.M.2    Jacobs, D.C.3    Van Wering, E.R.4    Van Dongen, J.J.5
  • 10
    • 0033894921 scopus 로고    scopus 로고
    • Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia
    • Verhagen OJ, Willemse MJ, Breunis WB, Wijkhuijs AJ, Jacobs DC, Joosten SA et al. Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia. Leukemia 2000; 14: 1426-1435.
    • (2000) Leukemia , vol.14 , pp. 1426-1435
    • Verhagen, O.J.1    Willemse, M.J.2    Breunis, W.B.3    Wijkhuijs, A.J.4    Jacobs, D.C.5    Joosten, S.A.6
  • 11
    • 0036114311 scopus 로고    scopus 로고
    • Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblasticleukemia are stable targets fordetection of minimalresidualdiseaseby real-time quantitative PCR
    • Van der Velden VHJ, Willemse MJ, Van der Schoot CE, Hahlen K, Van Wering ER, Van Dongen JJ. Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblasticleukemia are stable targets fordetection of minimalresidualdiseaseby real-time quantitative PCR. Leukemia 2002; 16: 928-936.
    • (2002) Leukemia , vol.16 , pp. 928-936
    • Van Der Velden, V.H.J.1    Willemse, M.J.2    Van Der Schoot, C.E.3    Hahlen, K.4    Van Wering, E.R.5    Van Dongen, J.J.6
  • 12
    • 11144355827 scopus 로고    scopus 로고
    • Rearranged T-cell receptor beta genes represent powerful targets for quantification of minimal residual disease in childhood and adult T-cell acute lymphoblastic leukemia
    • Bruggemann M, Van der Velden VHJ, Raff T, Droese J, Ritgen M, Pott C et al. Rearranged T-cell receptor beta genes represent powerful targets for quantification of minimal residual disease in childhood and adult T-cell acute lymphoblastic leukemia. Leukemia 2004; 18: 709-719.
    • (2004) Leukemia , vol.18 , pp. 709-719
    • Bruggemann, M.1    Van Der Velden, V.H.J.2    Raff, T.3    Droese, J.4    Ritgen, M.5    Pott, C.6
  • 13
    • 33947381440 scopus 로고    scopus 로고
    • Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting
    • Van der Velden VHJ, Panzer-Grumayer ER, Cazzaniga G, Flohr T, Sutton R, Schrauder A et al. Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting. Leukemia 2007; 21: 706-713.
    • (2007) Leukemia , vol.21 , pp. 706-713
    • Van Der Velden, V.H.J.1    Panzer-Grumayer, E.R.2    Cazzaniga, G.3    Flohr, T.4    Sutton, R.5    Schrauder, A.6
  • 14
    • 0036009611 scopus 로고    scopus 로고
    • AdVances in the immunological monitoring of childhood acute lymphoblastic leukaemia
    • Campana D, Coustan-Smith E. AdVances in the immunological monitoring of childhood acute lymphoblastic leukaemia. Best Pract Res Clin Haematol 2002; 15: 1-19.
    • (2002) Best Pract Res Clin Haematol , vol.15 , pp. 1-19
    • Campana, D.1    Coustan-Smith, E.2
  • 15
    • 0037265763 scopus 로고    scopus 로고
    • Flow cytometric follow-up of minimal residual disease in bone marrow gives prognostic information in children with acute lymphoblastic leukemia
    • Bjorklund E, Mazur J, Soderhall S, Porwit-MacDonald A. Flow cytometric follow-up of minimal residual disease in bone marrow gives prognostic information in children with acute lymphoblastic leukemia. Leukemia 2003; 17: 138-148.
    • (2003) Leukemia , vol.17 , pp. 138-148
    • Bjorklund, E.1    Mazur, J.2    Soderhall, S.3    Porwit-Macdonald, A.4
  • 16
    • 0037085750 scopus 로고    scopus 로고
    • Prognostic significance and modalities of flow cytometric minimal residual disease in childhood acute lymphoblastic leukemia
    • Dworzak MN, Fröschl G, Printz D, Mann G, Pötschger U, Mühlegger N et al. Prognostic significance and modalities of flow cytometric minimal residual disease in childhood acute lymphoblastic leukemia. Blood 2002; 99: 1952-1958.
    • (2002) Blood , vol.99 , pp. 1952-1958
    • Dworzak, M.N.1    Fröschl, G.2    Printz, D.3    Mann, G.4    Pötschger, U.5    Mühlegger, N.6
  • 17
    • 0032919213 scopus 로고    scopus 로고
    • Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemiausing immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemia
    • Pongers-Willemse MJ, Seriu T, Stolz F, d'Aniello E, Gameiro P, Pisa P et al. Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemiausing immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: report of the BIOMED-1 CONCERTED ACTION: investigation of minimal residual disease in acute leukemia. Leukemia 1999; 13: 110-118.
    • (1999) Leukemia , vol.13 , pp. 110-118
    • Pongers-Willemse, M.J.1    Seriu, T.2    Stolz, F.3    D'Aniello, E.4    Gameiro, P.5    Pisa, P.6
  • 18
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • Van Dongen JJ, Langerak AW, Bruggemann M, EVans PA, Hummel M, Lavender FL et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003; 17: 2257-2317.
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • Van Dongen, J.J.1    Langerak, A.W.2    Bruggemann, M.3    Evans, P.A.4    Hummel, M.5    Lavender, F.L.6
  • 19
    • 33947362505 scopus 로고    scopus 로고
    • Analysis of minimal residual disease by Ig/TCR gene rearrangements: Guidelines for interpretation of real-time quantitative PCR data
    • Van der Velden VHJ, Cazzaniga G, Schrauder A, Hancock J, Bader P, Panzer-Grumayer ER et al. Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data. Leukemia 2007; 21: 604-611.
    • (2007) Leukemia , vol.21 , pp. 604-611
    • Van Der Velden, V.H.J.1    Cazzaniga, G.2    Schrauder, A.3    Hancock, J.4    Bader, P.5    Panzer-Grumayer, E.R.6
  • 20
    • 77949424466 scopus 로고    scopus 로고
    • Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel Germany 18-20 September 2008
    • Brüggemann M, Schrauder A, Raff T, Pfeifer H, Dworzak M, Ottmann OG et al. Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008. Leukemia 2010; 24: 521-535.
    • (2010) Leukemia , vol.24 , pp. 521-535
    • Brüggemann, M.1    Schrauder, A.2    Raff, T.3    Pfeifer, H.4    Dworzak, M.5    Ottmann, O.G.6
  • 21
    • 27844468129 scopus 로고    scopus 로고
    • Four-color flow cytometry bypasses limitations of polymerase chain reaction for minimal residual disease detection in certain subsets of children with acute lymphoblastic leukemia
    • Robillard N, Cavé H, Méchinaud F, Guidal C, Garnache-Ottou F, Rorhlich PS et al. Four-color flow cytometry bypasses limitations of polymerase chain reaction for minimal residual disease detection in certain subsets of children with acute lymphoblastic leukemia. Haematologica 2005; 90: 1516-1523.
    • (2005) Haematologica , vol.90 , pp. 1516-1523
    • Robillard, N.1    Cavé, H.2    Méchinaud, F.3    Guidal, C.4    Garnache-Ottou, F.5    Rorhlich, P.S.6
  • 22
    • 58149331359 scopus 로고    scopus 로고
    • Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible
    • Dworzak MN, Gaipa G, Ratei R, Veltroni M, Schumich A, Maglia O et al. Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: multicentric assessment is feasible. Cytometry B Clin Cytom 2008; 74: 331-340.
    • (2008) Cytometry B Clin Cytom , vol.74 , pp. 331-340
    • Dworzak, M.N.1    Gaipa, G.2    Ratei, R.3    Veltroni, M.4    Schumich, A.5    Maglia, O.6
  • 23
    • 66749117163 scopus 로고    scopus 로고
    • Establishment and validation of a standard protocol for detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multicenter setting
    • Irving J, Jesson J, Virgo P, Case M, Minto L, Eyre L et al. Establishment and validation of a standard protocol for detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multicenter setting. Haematologica 2009; 94: 870-874.
    • (2009) Haematologica , vol.94 , pp. 870-874
    • Irving, J.1    Jesson, J.2    Virgo, P.3    Case, M.4    Minto, L.5    Eyre, L.6
  • 24
    • 67651205898 scopus 로고    scopus 로고
    • Quality control of flow cytometry data analysis for evaluation of minimal residual disease in bone marrow from acute leukemia patients during treatment
    • Björklund E, Matinlauri I, Tierens A, Axelsson S, Forestier E, Jacobsson S et al. Quality control of flow cytometry data analysis for evaluation of minimal residual disease in bone marrow from acute leukemia patients during treatment. J Pediatr Hematol Oncol 2009; 31: 406-415.
    • (2009) J Pediatr Hematol Oncol , vol.31 , pp. 406-415
    • Björklund, E.1    Matinlauri, I.2    Tierens, A.3    Axelsson, S.4    Forestier, E.5    Jacobsson, S.6
  • 25
    • 2342540402 scopus 로고    scopus 로고
    • Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia
    • Neale GA, Coustan-Smith E, Stow P, Pan Q, Chen X, Pui CH et al. Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia. Leukemia 2004; 18: 934-938.
    • (2004) Leukemia , vol.18 , pp. 934-938
    • Neale, G.A.1    Coustan-Smith, E.2    Stow, P.3    Pan, Q.4    Chen, X.5    Pui, C.H.6
  • 26
    • 5744223871 scopus 로고    scopus 로고
    • Analysis of minimal residual disease in childhood acute lymphoblastic leukemia: Comparison between RQ-PCR analysis of Ig/TcR gene rearrangements and multicolour flow cytometric immunophenotyping
    • Malec M, Van der Velden VHJ, Bjorklund E, Wijkhuijs JM, Soderhall S, Mazur J et al. Analysis of minimal residual disease in childhood acute lymphoblastic leukemia: comparison between RQ-PCR analysis of Ig/TcR gene rearrangements and multicolour flow cytometric immunophenotyping. Leukemia 2004; 18: 1630-1636.
    • (2004) Leukemia , vol.18 , pp. 1630-1636
    • Malec, M.1    Van Der Velden, V.H.J.2    Bjorklund, E.3    Wijkhuijs, J.M.4    Soderhall, S.5    Mazur, J.6
  • 27
    • 20144386608 scopus 로고    scopus 로고
    • Concurrent detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukaemia by flow cytometry and real-time PCR
    • Kerst G, Kreyenberg H, Roth C, Well C, Dietz K, Coustan-Smith E et al. Concurrent detection of minimal residual disease (MRD) in childhood acute lymphoblastic leukaemia by flow cytometry and real-time PCR. Br J Haematol 2005; 128: 774-782.
    • (2005) Br J Haematol , vol.128 , pp. 774-782
    • Kerst, G.1    Kreyenberg, H.2    Roth, C.3    Well, C.4    Dietz, K.5    Coustan-Smith, E.6
  • 29
    • 67649410242 scopus 로고    scopus 로고
    • Treating childhood acute lymphoblastic leukemia without cranial irradiation
    • Pui CH, Campana D, Pei D, Bowman WP, Sandlund JT, Kaste SC et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med 2009; 360: 2730-2741.
    • (2009) N Engl J Med , vol.360 , pp. 2730-2741
    • Pui, C.H.1    Campana, D.2    Pei, D.3    Bowman, W.P.4    Sandlund, J.T.5    Kaste, S.C.6
  • 30
    • 79959450187 scopus 로고    scopus 로고
    • New markers for minimal residual disease detection in acute lymphoblastic leukemia
    • Coustan-Smith E, Song G, Clark C, Key L, Liu P, Mehrpooya M et al. New markers for minimal residual disease detection in acute lymphoblastic leukemia. Blood 2011; 117: 6267-6276.
    • (2011) Blood , vol.117 , pp. 6267-6276
    • Coustan-Smith, E.1    Song, G.2    Clark, C.3    Key, L.4    Liu, P.5    Mehrpooya, M.6
  • 31
    • 79952008832 scopus 로고    scopus 로고
    • Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: A Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry
    • Thörn I, Forestier E, Botling J, Thuresson B, Wasslavik C, Björklund E et al. Minimal residual disease assessment in childhood acute lymphoblastic leukaemia: a Swedish multi-centre study comparing real-time polymerase chain reaction and multicolour flow cytometry. Br J Haematol 2011; 152: 743-753.
    • (2011) Br J Haematol , vol.152 , pp. 743-753
    • Thörn, I.1    Forestier, E.2    Botling, J.3    Thuresson, B.4    Wasslavik, C.5    Björklund, E.6
  • 32
    • 77949423027 scopus 로고    scopus 로고
    • Time point-dependent concordance of flow cytometry and RQ-PCR in the MRD detection in childhood ALL: The experience of the AIEOP-BFM-ALL MRD study group
    • abstract 700
    • Gaipa G, Cazzaniga G, Panzer-Grumayer RE, Veltroni M, Karawajew L, Silvestri D et al. Time point-dependent concordance of flow cytometry and RQ-PCR in the MRD detection in childhood ALL: the experience of the AIEOP-BFM-ALL MRD study group. Blood 2008; 112: abstract 700.
    • (2008) Blood , pp. 112
    • Gaipa, G.1    Cazzaniga, G.2    Panzer-Grumayer, R.E.3    Veltroni, M.4    Karawajew, L.5    Silvestri, D.6
  • 33
    • 77954727839 scopus 로고    scopus 로고
    • Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia
    • Stow P, Key L, Chen X, Pan Q, Neale GA, Coustan-Smith E et al. Clinical significance of low levels of minimal residual disease at the end of remission induction therapy in childhood acute lymphoblastic leukemia. Blood 2010; 115: 4657-4663.
    • (2010) Blood , vol.115 , pp. 4657-4663
    • Stow, P.1    Key, L.2    Chen, X.3    Pan, Q.4    Neale, G.A.5    Coustan-Smith, E.6
  • 34
    • 0034141517 scopus 로고    scopus 로고
    • Rapid molecular response during early induction chemotherapy preditcs a good outcome in childhood acute lymphoblastic leukemia
    • Panzer-Grumayer ER, Schneider M, Panzer S, Fasching K, Gadner H. Rapid molecular response during early induction chemotherapy preditcs a good outcome in childhood acute lymphoblastic leukemia. Blood 2000; 95: 790-794.
    • (2000) Blood , vol.95 , pp. 790-794
    • Panzer-Grumayer, E.R.1    Schneider, M.2    Panzer, S.3    Fasching, K.4    Gadner, H.5
  • 35
    • 0036660158 scopus 로고    scopus 로고
    • Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia
    • Coustan-Smith E, Sancho J, Behm FG, Hancock ML, Razzouk BI, Ribeiro RC et al. Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia. Blood 2002; 100: 52-58.
    • (2002) Blood , vol.100 , pp. 52-58
    • Coustan-Smith, E.1    Sancho, J.2    Behm, F.G.3    Hancock, M.L.4    Razzouk, B.I.5    Ribeiro, R.C.6
  • 36
    • 70449711125 scopus 로고    scopus 로고
    • Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
    • Basso G, Veltroni M, Valsecchi MG, Dworzak MN, Ratei R, Silvestri D et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol 2009; 27: 5168-5174.
    • (2009) J Clin Oncol , vol.27 , pp. 5168-5174
    • Basso, G.1    Veltroni, M.2    Valsecchi, M.G.3    Dworzak, M.N.4    Ratei, R.5    Silvestri, D.6
  • 37
    • 0034850655 scopus 로고    scopus 로고
    • Precursor-B-ALL with D(H)-J(H) gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14
    • Szczepanski T, Willemse MJ, Van Wering ER, Van Weerden JF, Kamps WA, Van Dongen JJ. Precursor-B-ALL with D(H)-J(H) gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14. Leukemia 2001; 15: 1415-1423.
    • (2001) Leukemia , vol.15 , pp. 1415-1423
    • Szczepanski, T.1    Willemse, M.J.2    Van Wering, E.R.3    Van Weerden, J.F.4    Kamps, W.A.5    Van Dongen, J.J.6
  • 38
    • 77952630014 scopus 로고    scopus 로고
    • Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: Evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group
    • Dworzak MN, Gaipa G, Schumich A, Maglia O, Ratei R, Veltroni M et al. Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group. Cytometry B Clin Cytom 2010; 78: 147-153.
    • (2010) Cytometry B Clin Cytom , vol.78 , pp. 147-153
    • Dworzak, M.N.1    Gaipa, G.2    Schumich, A.3    Maglia, O.4    Ratei, R.5    Veltroni, M.6
  • 39
    • 77952604861 scopus 로고    scopus 로고
    • Immaturity associated antigens are lost during induction for T cell lymphoblastic leukemia: Implications for minimal residual disease detection
    • Roshal M, Fromm JR, Winter S, Dunsmore K, Wood BL. Immaturity associated antigens are lost during induction for T cell lymphoblastic leukemia: implications for minimal residual disease detection. Cytometry B Clin Cytom 2010; 78: 139-146.
    • (2010) Cytometry B Clin Cytom , vol.78 , pp. 139-146
    • Roshal, M.1    Fromm, J.R.2    Winter, S.3    Dunsmore, K.4    Wood, B.L.5
  • 40
    • 80051783672 scopus 로고    scopus 로고
    • Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment
    • Eckert C, Flohr T, Koehler R, Hagedorn N, Moericke A, Stanulla M et al. Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment. Leukemia 2011; 25: 1305-1313.
    • (2011) Leukemia , vol.25 , pp. 1305-1313
    • Eckert, C.1    Flohr, T.2    Koehler, R.3    Hagedorn, N.4    Moericke, A.5    Stanulla, M.6


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