A random urine test can identify patients at risk of mesalamine non-adherence: A prospective study

American Journal of Gastroenterology

Volumn 108, Issue 2, 2013, Pages 249-255

  Gifford, Anne E ^a   Berg, Anders H ^a   Lahiff, Conor ^a   Cheifetz, Adam S ^a   Horowitz, Gary ^a   Moss, Alan C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOSALICYLIC ACID; MESALAZINE;

ADULT; ARTICLE; COLORIMETRY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HIGH RISK PATIENT; HUMAN; LIQUID CHROMATOGRAPHY; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MORISKY MEDICATION ADHERENCE SCALE 8; OBSERVATIONAL STUDY; PATIENT COMPLIANCE; PATIENT IDENTIFICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOM URINE TEST; RATING SCALE; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; ULCERATIVE C; URINALYSIS;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; COLITIS, ULCERATIVE; COLORIMETRY; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MESALAMINE; MIDDLE AGED; PROSPECTIVE STUDIES; RECURRENCE; SALICYLIC ACID; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TERTIARY CARE CENTERS;

EID: 84873568368     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2012.419     Document Type: Article

References (28)

1. Kane SV, Cohen RD, Aikens JE et al. Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis. Am J Gastroenterol 2001; 96: 2929-33. (Pubitemid 32959535)
2. Kane SV, Sumner M, Solomon D et al. Twelve-month persistency with oral 5-aminosalicylic acid therapy for ulcerative colitis: Results from a large pharmacy prescriptions database. Dig Dis Sci 2011; 56: 3463-70.
3. Kane S, Huo D, Aikens J et al. Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis. Am J Med 2003; 114: 39-43. (Pubitemid 36126514)
4. Kane S, Shaya F. Medication non-adherence is associated with increased medical health care costs. Dig Dis Sci 2008; 53: 1020-4. (Pubitemid 351379831)
5. Cerveny P, Bortlik M, Kubena A et al. Non-adherence in infl ammatory bowel disease: Results of factor analysis. Infl amm Bowel Dis 2007; 13: 1244-9. (Pubitemid 47597771)
6. Ediger JP, Walker JR, Graff L et al. Predictors of medication adherence in infl ammatory bowel disease. Am J Gastroenterol 2007; 102: 1417-26. (Pubitemid 46976288)
7. Kane SV. Systematic review: Adherence issues in the treatment of ulcerative colitis. Aliment Pharmacol Th er 2006; 23: 577-85.
8. Trindade AJ, Ehrlich A, Kornbluth A et al. Are your patients taking their medicine? Validation of a new adherence scale in patients with infl ammatory bowel disease and comparison with physician perception of adherence. Infl amm Bowel Dis 2011; 17: 599-604.
9. Garfi eld S, Cliff ord S, Eliasson L et al. Suitability of measures of selfreported medication adherence for routine clinical use: A systematic review. BMC Med Res Methodol 2011; 11: 149.
10. Shi L, LiüJ, Koleva Y et al. Concordance of adherence measurement using self-reported adherence questionnaires and medication monitoring devices. Pharmacoeconomics 2010; 28: 1097-107.
11. Kane S, Becker B, Harmsen WS et al. Use of a screening tool to determine nonadherent behavior in infl ammatory bowel disease. Am J Gastroenterol 2012; 107: 154-60.
12. Trindade AJ, Morisky DE, Ehrlich AC et al. Current practice and perception of screening for medication adherence in infl ammatory bowel disease. J Clin Gastroenterol 2011; 45: 878-82.
13. Cook PF, Emiliozzi S, El Hajj D et al. Telephone nurse counseling for medication adherence in ulcerative colitis: A preliminary study. Patient Educ Couns 2010; 81: 182-6.
14. Dilger K, Trenk D, Rossle M et al. A clinical trial on absorption and N-acetylation of oral and rectal mesalazine. Eur J Clin Invest 2007; 37: 558-65. (Pubitemid 46920187)
15. Myers B, Evans DN, Rhodes J et al. Metabolism and urinary excretion of 5-amino salicylic acid in healthy volunteers when given intravenously or released for absorption at diff erent sites in the gastrointestinal tract. Gut 1987; 28: 196-200. (Pubitemid 17027391)
16. Sandborn WJ, SB. Systematic review: The pharmacokinetic profi les of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis. Aliment Pharmacol Th er 2003; 17: 29-42. (Pubitemid 36140432)
17. Nobilis M, Vybiralova Z, Sladkova K et al. High-performance liquidchromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma. J Chromatogr A 2006; 1119: 299-308. (Pubitemid 43831900)
18. Farid NA, Born GS, Kessler WV et al. Improved colorimetric determination of salicylic acid and its metabolites in urine. Clin Chem 1975; 21: 1167-8.
19. Shaw IS, Jobson BA, Silverman D et al. Is your patient taking the medicine? A simple assay to measure compliance with 5-aminosalicylic acidcontaining compounds. Aliment Pharmacol Th er 2002; 16: 2053-9. (Pubitemid 36009168)
20. Morisky DE, Ang A, Krousel-Wood M et al. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens (Greenwich) 2008; 10: 348-54.
21. Walmsley RS, Ayres RC, Pounder RE et al. A simple clinical colitis activity index. Gut 1998; 43: 29-32. (Pubitemid 28335486)
22. Hess LM, Raebel MA, Conner DA et al. Measurement of adherence in pharmacy administrative databases: A proposal for standard defi nitions and preferred measures. Ann Pharmacother 2006; 40: 1280-8. (Pubitemid 44204957)
23. Krousel-Wood M, Islam T, Webber LS et al. New medication adherence scale versus pharmacy fi ll rates in seniors with hypertension. Am J Manag Care 2009; 15: 59-66.
24. Bernal I, Domenech E, Garcia-Planella E et al. Medication-taking behavior in a cohort of patients with infl ammatory bowel disease. Dig Dis Sci 2006; 51: 2165-9.
25. Higgins PD, Rubin DT, Kaulback K et al. Systematic review: Impact of nonadherence to 5-aminosalicylic acid products on the frequency and cost of ulcerative colitis fl ares. Aliment Pharmacol Th er 2009; 29: 247-57.
26. Farmer KC. Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther 1999; 21: 1074-90. (Pubitemid 29326165)
27. Moshkovska T, Stone MA, Clatworthy J et al. An investigation of medication adherence to 5-aminosalicylic acid therapy in patients with ulcerative colitis, using self-report and urinary drug excretion measurements. Aliment Pharmacol Th er 2009; 30: 1118-27.
28. Podsadecki TJ, Vrijens BC, Tousset EP et al. " White coat compliance " limits the reliability of therapeutic drug monitoring in HIV-1-infected patients. HIV Clin Trials 2008; 9: 238-46.