Cerebral Toxoplasmosis Mimicking Subacute Meningitis in HIV-Infected Patients; a Cohort Study from Indonesia

PLoS Neglected Tropical Diseases

Volumn 7, Issue 1, 2013, Pages

  Ganiem, A Rizal ^a   Dian, Sofiati ^a   Indriati, Agnes ^a   Chaidir, Lidya ^b   Wisaksana, Rudi ^a   Sturm, Patrick ^c   Melchers, Willem ^c   van der Ven, Andre ^c   Parwati, Ida ^a   van Crevel, Reinout ^c  

^a Hasan Sadikin Hospital   (Indonesia)

^b PADJADJARAN UNIVERSITY   (Indonesia)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G;

ADULT; ARTICLE; CEREBROSPINAL FLUID; COHORT ANALYSIS; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INDONESIA; MAJOR CLINICAL STUDY; MALE; MENINGITIS; MORTALITY; NEURORADIOLOGY; PROPHYLAXIS; REAL TIME POLYMERASE CHAIN REACTION; SEROLOGY; TOXOPLASMA; TOXOPLASMA GONDII; TOXOPLASMOSIS;

EID: 84873499520     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001994     Document Type: Article

References (30)

1. Jarvis JN, Meintjes G, Williams A, Brown Y, Crede T, et al. (2010) Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases. BMC Infect Dis 10: 67.
2. Kongsiriwattanakul S, Suankratay C, (2011) Central nervous system infections in HIV-infected patients hospitalized at King Chulalongkorn Memorial Hospital. J Med Assoc Thai 94: 551-558.
3. Hakim JG, Gangaidzo IT, Heyderman RS, Mielke J, Mushangi E, et al. (2000) Impact of HIV infection on meningitis in Harare, Zimbabwe: a prospective study of 406 predominantly adult patients. AIDS 14: 1401-1407.
4. Ganiem AR, Parwati I, Wisaksana R, van der Zanden A, van de Beek D, et al. (2009) The effect of HIV infection on adult meningitis in Indonesia: a prospective cohort study. AIDS 23: 2309-2316.
5. Antinori A, Larussa D, Cingolani A, Lorenzini P, Bossolasco S, et al. (2004) Prevalence, associated factors, and prognostic determinants of AIDS-related toxoplasmic encephalitis in the era of advanced highly active antiretroviral therapy. Clin Infect Dis 39: 1681-1691.
6. Hoffmann C, Ernst M, Meyer P, Wolf E, Rosenkranz T, et al. (2007) Evolving characteristics of toxoplasmosis in patients infected with human immunodeficiency virus-1: clinical course and Toxoplasma gondii-specific immune responses. Clin Microbiol Infect 13: 510-515.
7. Naba MR, Kanafani ZA, Awar GN, Kanj SS, (2010) Profile of opportunistic infections in HIV-infected patients at a tertiary care center in Lebanon. J Infect Public Health 3: 130-133.
8. Nissapatorn V, Lee C, Quek KF, Leong CL, Mahmud R, et al. (2004) Toxoplasmosis in HIV/AIDS patients: a current situation. Jpn J Infect Dis 57: 160-165.
9. Mayor AM, Fernandez Santos DM, Dworkin MS, Rios-Olivares E, Hunter-Mellado RF, (2011) Toxoplasmic encephalitis in an AIDS cohort at Puerto Rico before and after highly active antiretroviral therapy (HAART). Am J Trop Med Hyg 84: 838-841.
10. Skiest DJ, (2002) Focal neurological disease in patients with acquired immunodeficiency syndrome. Clin Infect Dis 34: 103-115.
11. Savelkoul PH, Catsburg A, Mulder S, Oostendorp L, Schirm J, et al. (2006) Detection of Mycobacterium tuberculosis complex with Real Time PCR: comparison of different primer-probe sets based on the IS6110 element. J Microbiol Methods 66: 177-180.
12. Lin MH, Chen TC, Kuo TT, Tseng CC, Tseng CP, (2000) Real-time PCR for quantitative detection of Toxoplasma gondii. J Clin Microbiol 38: 4121-4125.
13. Thwaites GE, Nguyen DB, Nguyen HD, Hoang TQ, Do TT, et al. (2004) Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 351: 1741-1751.
14. Montoya JG, Liesenfeld O, (2004) Toxoplasmosis. Lancet 363: 1965-1976.
15. Helbok R, Pongpakdee S, Yenjun S, Dent W, Beer R, et al. (2006) Chronic meningitis in Thailand. Clinical characteristics, laboratory data and outcome in patients with specific reference to tuberculosis and cryptococcosis. Neuroepidemiology 26: 37-44.
16. Marais S, Pepper DJ, Schutz C, Wilkinson RJ, Meintjes G, (2011) Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting. PLoS One 6: e20077.
17. Thwaites GE, Duc Bang N, Huy Dung N, Thi Quy H, Thi Tuong Oanh D, et al. (2005) The influence of HIV infection on clinical presentation, response to treatment, and outcome in adults with Tuberculous meningitis. J Infect Dis 192: 2134-2141.
18. Porter SB, Sande MA, (1992) Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. N Engl J Med 327: 1643-1648.
19. Renold C, Sugar A, Chave JP, Perrin L, Delavelle J, et al. (1992) Toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome. Medicine (Baltimore) 71: 224-239.
20. Garcia-Gubern C, Fuentes CR, Colon-Rolon L, Masvidal D, (2010) Spinal cord toxoplasmosis as an unusual presentation of AIDS: case report and review of the literature. Int J Emerg Med 3: 439-442.
21. Bretagne S, (2003) Molecular diagnostics in clinical parasitology and mycology: limits of the current polymerase chain reaction (PCR) assays and interest of the real-time PCR assays. Clin Microbiol Infect 9: 505-511.
22. Remington JS, Thulliez P, Montoya JG, (2004) Recent developments for diagnosis of toxoplasmosis. J Clin Microbiol 42: 941-945.
23. Cinque P, Scarpellini P, Vago L, Linde A, Lazzarin A, (1997) Diagnosis of central nervous system complications in HIV-infected patients: cerebrospinal fluid analysis by the polymerase chain reaction. AIDS 11: 1-17.
24. Correia CC, Melo HR, Costa VM, (2010) Influence of neurotoxoplasmosis characteristics on real-time PCR sensitivity among AIDS patients in Brazil. Trans R Soc Trop Med Hyg 104: 24-28.
25. Barratt JL, Harkness J, Marriott D, Ellis JT, Stark D, (2010) Importance of nonenteric protozoan infections in immunocompromised people. Clin Microbiol Rev 23: 795-836.
26. Lanjewar DN, (2011) The spectrum of clinical and pathological manifestations of AIDS in a consecutive series of 236 autopsied cases in mumbai, India. Patholog Res Int 2011: 547618.
27. Shin DW, Cha DY, Hua QJ, Cha GH, Lee YH, (2009) Seroprevalence of Toxoplasma gondii infection and characteristics of seropositive patients in general hospitals in Daejeon, Korea. Korean J Parasitol 47: 125-130.
28. Osunkalu VO, Akanmu SA, Ofomah NJ, Onyiaorah IV, Adediran AA, et al. (2011) Seroprevalence of Toxoplasma gondii IgG antibody in HIV-infected patients at the Lagos University Teaching Hospital. HIV AIDS (Auckl) 3: 101-105.
29. Vidal JE, Hernandez AV, de Oliveira AC, Dauar RF, Barbosa SP Jr, et al. (2005) Cerebral toxoplasmosis in HIV-positive patients in Brazil: clinical features and predictors of treatment response in the HAART era. AIDS Patient Care STDS 19: 626-634.
30. Quan C, Lu CZ, Qiao J, Xiao BG, Li X, (2006) Comparative evaluation of early diagnosis of tuberculous meningitis by different assays. J Clin Microbiol 44: 3160-3166.