A new explained-variance based genetic risk score for predictive modeling of disease risk

Statistical Applications in Genetics and Molecular Biology

Volumn 11, Issue 4, 2012, Pages

  Che, Ronglin ^a   Motsinger Reif, Alison A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Explained variance; Polygenic; Predictive modeling; Simple count genetic risk score; Weighted genetic risk score

Indexed keywords

ARTICLE; COMPARATIVE STUDY; EXPLAINED VARIANCE WEIGHTED GENETIC RISK SCORE; GENE FREQUENCY; GENETIC MODEL; GENETIC RISK; GENETIC VARIABILITY; HUMAN; LOGISTIC REGRESSION GENETIC RISK SCORE; MULTIFACTORIAL INHERITANCE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; ODDS RATIO WEIGHTED GENETIC RISK SCORE; PENETRANCE; POLYGENIC GENETIC RISK SCORE; PREDICTIVE VALUE; RISK FACTOR; SAMPLE SIZE; SIMPLE COUNT GENETIC RISK SCORE; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC MARKER; GENETIC PREDISPOSITION; RISK; STATISTICAL MODEL;

DATABASES, GENETIC; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MODELS, GENETIC; MODELS, STATISTICAL; MULTIFACTORIAL INHERITANCE; ODDS RATIO; PENETRANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84873486524     PISSN: None     EISSN: 15446115     Source Type: Journal    
DOI: 10.1515/1544-6115.1796     Document Type: Article

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