Vancomycin-resistant enterococcal meningitis in an autologous stem cell transplant recipient cured with linezolid

Transplant Infectious Disease

Volumn 15, Issue 1, 2013, Pages

  Frasca, K L ^a   Schuster, M G ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Bone marrow transplantation; HSCT; Linezolid; Meningitis; Vancomycin resistant enterococci; VRE

Indexed keywords

AMPICILLIN; BORTEZOMIB; CHLORAMPHENICOL; DAPTOMYCIN; DEXAMETHASONE; FLUCONAZOLE; GENTAMICIN; LEVOFLOXACIN; LINEZOLID; MELPHALAN; PIPERACILLIN PLUS TAZOBACTAM; STREPTOMYCIN; THALIDOMIDE; TOBRAMYCIN; VANCOMYCIN;

ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BACTERIAL MENINGITIS; BLOOD CULTURE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CEREBROSPINAL FLUID CULTURE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSPNEA; ENTEROCOCCAL INFECTION; FEBRILE NEUTROPENIA; FEMALE; FEVER; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTENSIVE CARE UNIT; MONOTHERAPY; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; NEUTROPHIL COUNT; PRIORITY JOURNAL; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT OUTCOME; URINE CULTURE; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ACETAMIDES; ANTI-INFECTIVE AGENTS; ENTEROCOCCUS; FEMALE; GRAM-POSITIVE BACTERIAL INFECTIONS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOCOMPROMISED HOST; MENINGITIS, BACTERIAL; MIDDLE AGED; OXAZOLIDINONES; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; VANCOMYCIN RESISTANCE;

EID: 84873474760     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/tid.12032     Document Type: Article

References (28)

1. Tsai TN, Wu CP, Peng MY, et al. Short course of linezolid treatment for vancomycin-resistant Enterococcus faecium meningitis. Int J Clin Pract 2006; 60 (6): 740-741.
2. Pintado V, Cabellos C, Moreno S, et al. Enterococcal meningitis: a clinical study of 39 cases and review of the literature. Medicine (Baltimore) 2003; 82 (5): 3463-3464.
3. Jones RN. Resistance patterns among nosocomial pathogens: trends over the past few years. Chest 2001; 119 (Suppl 2): 397S-404S.
4. Murray BE. Vancomycin-resistant enterococcal infections. N Engl J Med 2000; 342 (10): 710-721.
5. Linden PK. Optimizing therapy for vancomycin-resistant enterococci (VRE). Semin Respir Crit Care Med 2007; 28 (6): 632-645.
6. Koc Y, Snydman DR, Schenkein DS, et al. Vancomycin-resistant enterococcal infections in bone marrow transplant recipients. Bone Marrow Transplant 1998; 22 (2): 207-209.
7. Steinmetz MP, Vogelbaum MA, De Georgia MA, et al. Successful treatment of vancomycin-resistant Enterococcus meningitis with linezolid: case report and review of the literature. Crit Care Med 2001; 29 (12): 2383-2385.
8. Hachem R, Afif C, Gokaslan Z, et al. Successful treatment of vancomycin-resistant Enterococcus meningitis with linezolid. Eur J Clin Microbiol Infect Dis 2001; 20 (6): 432-434.
9. Shaikh ZH, Peloquin CA, Ericsson CD. Successful treatment of vancomycin-resistant Enterococcus faecium meningitis with linezolid: case report and literature review. Scand J Infect Dis 2001; 33 (5): 375-379.
10. Tush GM, Huneycutt S, Phillips A, et al. Intraventricular quinupristin/dalfopristin for the treatment of vancomycin-resistant Enterococcus faecium shunt infection. Clin Infect Dis 1998; 26 (6): 1460-1461.
11. Nachman SA, Verma R, Egnor M. Vancomycin-resistant Enterococcus faecium shunt infection in an infant: an antibiotic cure. Microb Drug Resist 1995; 1 (1): 95-96.
12. Losonsky GA, Wolf A, Schwalbe RS, et al. Successful treatment of meningitis due to multiply resistant Enterococcus faecium with a combination of intrathecal teicoplanin and intravenous antimicrobial agents. Clin Infect Dis 1994; 19 (1): 163-165.
13. Pérez Mato S, Robinson S, Bégué RE. Vancomycin-resistant Enterococcus faecium meningitis successfully treated with chloramphenicol. Pediatr Infect Dis J 1999; 18 (5): 483-484.
14. Sarma PS, Mohanty S. Mixed meningitis: association of Acinetobacter calcoaceticus var. lwoffi and Streptococcus faecium. Postgrad Med J 1995; 71 (835): 295-296.
15. Zanella RC, Valdetaro F, Lovgren M, et al. First confirmed case of vancomycin-resistant Enterococcus faecium with vanA phenotype from Brazil: isolation from a meningitis case in Sao Paulo. Microb Drug Resist 1999; 5 (2): 159-162.
16. Gransden WR, King A, Marossy D, et al. Quinupristin/dalfopristin in neonatal Enterococcus faecium meningitis. Arch Dis Child Fetal Neonatal Ed 1998; 78 (3): F235-F236.
17. Dever LL, Smith SM, Dejesus D, et al. Treatment of vancomycin-resistant Enterococcus faecium infections with an investigational streptogramin antibiotic (quinupristin/dalfopristin): a report of fifteen cases. Microb Drug Resist 1996; 2 (4): 407-413.
18. Ergaz Z, Arada I, Bar-Oz B, et al. Elimination of vancomycin-resistant enterococci from a neonatal intensive care unit following an outbreak. J Hosp Infect 2010; 74 (4): 370-376.
19. Zeana C, Kubin CJ, Della-Latta P, et al. Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: case report and review of the literature. Clin Infect Dis 2001; 33 (4): 477-482.
20. Ntziora F, Falagas M. Linezolid for the treatment of patients with central nervous system infection. Ann Pharmacother 2007; 41 (2): 296-308.
21. Le J, Bookstaver B, Rudisill C. Treatment of meningitis caused by vancomycin-resistant Enterococcus faecium: high-dose and combination daptomycin therapy. Ann Pharmacother 2010; 44 (12): 2001-2006.
22. Kraft S, Mackler E, Schlickman P, Welch R, DePestel DD. Outcomes of therapy: vancomycin-resistant enterococcal bacteremia in hematology and bone marrow transplant patients. Support Care Cancer 2011; 19 (12): 1969-1974.
23. Crank CW, Scheetz MH, Brielmaier B, et al. Comparison of outcomes from daptomycin or linezolid treatment for vancomycin-resistant enterococcal bloodstream infection: a retrospective, multicenter, cohort study. Clin Therapeutics 2010; 32 (10): 1713-1719.
24. Twilla JD, Finch CK, Usery JB, et al. Vancomycin-resistant Enterococcus bacteremia: an evaluation of treatment with linezolid or daptomycin. J Hospital Med 2012; 7 (3): 243-248.
25. Falagas ME, Giannopoulou KP, Ntziora F, et al. Daptomycin for endocarditis and/or bacteraemia: a systematic review of the experimental and clinical evidence. J Antimicrob Chemother 2007; 60 (1): 7-19.
26. Raad I, Hachem R, Hanna H, et al. Prospective, randomized study comparing quinupristin-dalfopristin with linezolid in the treatment of vancomycin-resistant Enterococcus faecium infections. J Antimicrob Chemother 2004; 53: 646-649.
27. Cohen N, Mihu CN, Seo SK, et al. Hematologic safety profile of linezolid in the early periengraftment period after allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2009; 15 (10): 1337-1341.
28. Smith PF, Birmingham MC, Noskin GA, et al. Efficacy and pharmacokinetics of linezolid for treatment of resistant Gram-positive infections in cancer patients with neutropenia. Ann Oncol 2003; 14: 795-801.