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Volumn 114, Issue 3, 2013, Pages 361-370

Perivagal antagonist treatment in rats selectively blocks the reflex and afferent responses of vagal lung C fibers to intravenous agonists

Author keywords

5 HT3 receptors; Lung; P2X receptors; Perivagal antagonist treatment; Reflex; TRPV1; Vagal C fibers

Indexed keywords

CAPSAICIN; PURINERGIC P2 RECEPTOR AGONIST; PURINERGIC P2X RECEPTOR; PURINERGIC P2X RECEPTOR ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; VANILLOID RECEPTOR; VANILLOID RECEPTOR SUBTYPE 1;

EID: 84873468667     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00977.2012     Document Type: Article
Times cited : (15)

References (62)
  • 1
    • 84856223850 scopus 로고    scopus 로고
    • Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat
    • Aizawa N, Wyndaele JJ, Homma Y, Igawa Y. Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat. Neurourol Urodyn 31: 148-155, 2012.
    • (2012) Neurourol Urodyn , vol.31 , pp. 148-155
    • Aizawa, N.1    Wyndaele, J.J.2    Homma, Y.3    Igawa, Y.4
  • 4
    • 15044357154 scopus 로고    scopus 로고
    • Effect of 5-hydroxytryptamine on vagal C-fiber subtypes in guinea pig lungs
    • Chuaychoo B, Lee MG, Kollarik M, Undem BJ. Effect of 5-hydroxytryptamine on vagal C-fiber subtypes in guinea pig lungs. Pulm Pharmacol Ther 18: 269-276, 2005.
    • (2005) Pulm Pharmacol Ther , vol.18 , pp. 269-276
    • Chuaychoo, B.1    Lee, M.G.2    Kollarik, M.3    Undem, B.J.4
  • 5
    • 0001297794 scopus 로고
    • Reflexes evoked from tracheobronchial tree and lungs
    • Control of Breathing. Bethesda, MD: Am. Physiol. Soc, sect. 3, pt. 1, chapt 12
    • Coleridge HM, Coleridge JCG. Reflexes evoked from tracheobronchial tree and lungs. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc, 1986, sect. 3, vol. II, pt. 1, chapt. 12, p. 395-429.
    • (1986) Handbook of Physiology. The Respiratory System , vol.2 , pp. 395-429
    • Coleridge, H.M.1    Coleridge, J.C.G.2
  • 6
    • 0031460255 scopus 로고    scopus 로고
    • CCK-8 activates hepatic vagal C-fiber afferents
    • Cox JE, Randich A. CCK-8 activates hepatic vagal C-fiber afferents. Brain Res 776: 189-194, 1997.
    • (1997) Brain Res , vol.776 , pp. 189-194
    • Cox, J.E.1    Randich, A.2
  • 7
    • 77149142887 scopus 로고    scopus 로고
    • Fast intra-axonal transport: Beginning, development and post-genome advances
    • Dahlstrom AB. Fast intra-axonal transport: beginning, development and post-genome advances. Prog Neurobiol 90: 119-145, 2010.
    • (2010) Prog Neurobiol , vol.90 , pp. 119-145
    • Dahlstrom, A.B.1
  • 8
    • 84862285513 scopus 로고    scopus 로고
    • Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig
    • Delescluse I, Mace H, Adcock J. Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig. Br J Pharmacol 166: 1822- 1832, 2012.
    • (2012) Br J Pharmacol , vol.166 , pp. 1822-1832
    • Delescluse, I.1    MacE, H.2    Adcock, J.3
  • 11
    • 77955140007 scopus 로고    scopus 로고
    • Cardio-respiratory reflexes evoked by phenylbiguanide in rats involve vagal afferents which are not sensitive to capsaicin
    • Dutta A, Deshpande SB. Cardio-respiratory reflexes evoked by phenylbiguanide in rats involve vagal afferents which are not sensitive to capsaicin. Acta Physiol (Oxf) 200: 87-95, 2010.
    • (2010) Acta Physiol (Oxf) , vol.200 , pp. 87-95
    • Dutta, A.1    Deshpande, S.B.2
  • 12
    • 67349279187 scopus 로고    scopus 로고
    • The TRPV1 ion channel: Implications for respiratory sensation and dyspnea
    • Fisher JT. The TRPV1 ion channel: implications for respiratory sensation and dyspnea. Respir Physiol Neurobiol 167: 45-52, 2009.
    • (2009) Respir Physiol Neurobiol , vol.167 , pp. 45-52
    • Fisher, J.T.1
  • 13
    • 79960190331 scopus 로고    scopus 로고
    • TRPM8 and dyspnea: From the frigid and fascinating past to the cool future?
    • Fisher JT. TRPM8 and dyspnea: from the frigid and fascinating past to the cool future? Curr Opin Pharmacol 11: 218-223, 2011.
    • (2011) Curr Opin Pharmacol , vol.11 , pp. 218-223
    • Fisher, J.T.1
  • 14
    • 0032526185 scopus 로고    scopus 로고
    • Role of 5-HT3 receptors in activation of abdominal sympathetic C fibre afferents during ischaemia in cats
    • Fu LW, Longhurst JC. Role of 5-HT3 receptors in activation of abdominal sympathetic C fibre afferents during ischaemia in cats. J Physiol 509: 729-740, 1998.
    • (1998) J Physiol , vol.509 , pp. 729-740
    • Fu, L.W.1    Longhurst, J.C.2
  • 16
    • 84866090064 scopus 로고    scopus 로고
    • Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin
    • Grace M, Birrell MA, Dubuis E, Maher SA, Belvisi MG. Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. Thorax 67: 891-900, 2012.
    • (2012) Thorax , vol.67 , pp. 891-900
    • Grace, M.1    Birrell, M.A.2    Dubuis, E.3    Maher, S.A.4    Belvisi, M.G.5
  • 17
    • 27944458911 scopus 로고    scopus 로고
    • Sensitization of pulmonary chemosensitive neurons by bombesin-like peptides in rats
    • Gu Q, Lee LY. Sensitization of pulmonary chemosensitive neurons by bombesin-like peptides in rats. Am J Physiol Lung Cell Mol Physiol 289: L1104-L1112, 2005.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.289
    • Gu, Q.1    Lee, L.Y.2
  • 18
    • 33746266193 scopus 로고    scopus 로고
    • Hypersensitivity of pulmonary chemosensitive neurons induced by activation of protease-activated receptor-2 in rats
    • Gu Q, Lee LY. Hypersensitivity of pulmonary chemosensitive neurons induced by activation of protease-activated receptor-2 in rats. J Physiol 574: 867-876, 2006.
    • (2006) J Physiol , vol.574 , pp. 867-876
    • Gu, Q.1    Lee, L.Y.2
  • 20
    • 0035370702 scopus 로고    scopus 로고
    • ATP affects both axons and Schwann cells of unmyelinated C fibres
    • Irnich D, Burgstahler R, Bostock H, Grafe P. ATP affects both axons and Schwann cells of unmyelinated C fibres. Pain 92: 343-350, 2001.
    • (2001) Pain , vol.92 , pp. 343-350
    • Irnich, D.1    Burgstahler, R.2    Bostock, H.3    Grafe, P.4
  • 21
    • 0036499737 scopus 로고    scopus 로고
    • ATP stimulates peripheral axons in human, rat and mouse-differential involvement of A(2B) adenosine and P2X purinergic receptors
    • Irnich D, Tracey DJ, Polten J, Burgstahler R, Grafe P. ATP stimulates peripheral axons in human, rat and mouse-differential involvement of A(2B) adenosine and P2X purinergic receptors. Neuroscience 110: 123- 129, 2002.
    • (2002) Neuroscience , vol.110 , pp. 123-129
    • Irnich, D.1    Tracey, D.J.2    Polten, J.3    Burgstahler, R.4    Grafe, P.5
  • 22
    • 0025959671 scopus 로고
    • Molecular biology of serotonin receptors
    • Julius D. Molecular biology of serotonin receptors. Annu Rev Neurosci 14: 335-360, 1991.
    • (1991) Annu Rev Neurosci , vol.14 , pp. 335-360
    • Julius, D.1
  • 23
    • 33748569819 scopus 로고    scopus 로고
    • Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs
    • Kamei J, Takahashi Y. Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs. Eur J Pharmacol 547: 160-164, 2006.
    • (2006) Eur J Pharmacol , vol.547 , pp. 160-164
    • Kamei, J.1    Takahashi, Y.2
  • 24
    • 12344318566 scopus 로고    scopus 로고
    • Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers
    • Kang YM, Bielefeldt K, Gebhart GF. Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers. J Neurophysiol 91: 1981-1989, 2004.
    • (2004) J Neurophysiol , vol.91 , pp. 1981-1989
    • Kang, Y.M.1    Bielefeldt, K.2    Gebhart, G.F.3
  • 25
    • 49849104617 scopus 로고    scopus 로고
    • Vanilloid-induced conduction analgesia: Selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity
    • Kissin I. Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity. Anesth Analg 107: 271-281, 2008.
    • (2008) Anesth Analg , vol.107 , pp. 271-281
    • Kissin, I.1
  • 26
    • 1542329731 scopus 로고    scopus 로고
    • Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice
    • Kollarik M, Undem BJ. Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. J Physiol 555: 115-123, 2004.
    • (2004) J Physiol , vol.555 , pp. 115-123
    • Kollarik, M.1    Undem, B.J.2
  • 27
    • 0031908662 scopus 로고    scopus 로고
    • Stimulation of vagal pulmonary C fibers by inhaled wood smoke in rats
    • Lai CJ, Kou YR. Stimulation of vagal pulmonary C fibers by inhaled wood smoke in rats. J Appl Physiol 84: 30-36, 1998.
    • (1998) J Appl Physiol , vol.84 , pp. 30-36
    • Lai, C.J.1    Kou, Y.R.2
  • 28
    • 0026550871 scopus 로고
    • Acute effects of acrolein on breathing: Role of vagal bronchopulmonary afferents
    • Lee BP, Morton RF, Lee LY. Acute effects of acrolein on breathing: role of vagal bronchopulmonary afferents. J Appl Physiol 72: 1050-1056, 1992.
    • (1992) J Appl Physiol , vol.72 , pp. 1050-1056
    • Lee, B.P.1    Morton, R.F.2    Lee, L.Y.3
  • 29
    • 0028244329 scopus 로고
    • Capsazepine abolishes pulmonary chemoreflexes induced by capsaicin in anesthetized rats
    • Lee LY, Lundberg JM. Capsazepine abolishes pulmonary chemoreflexes induced by capsaicin in anesthetized rats. J Appl Physiol 76: 1848-1855, 1994.
    • (1994) J Appl Physiol , vol.76 , pp. 1848-1855
    • Lee, L.Y.1    Lundberg, J.M.2
  • 30
    • 0035116372 scopus 로고    scopus 로고
    • Afferent properties and reflex functions of bronchopulmonary C-fibers
    • Lee LY, Pisarri TE. Afferent properties and reflex functions of bronchopulmonary C-fibers. Respir Physiol 125: 47-65, 2001.
    • (2001) Respir Physiol , vol.125 , pp. 47-65
    • Lee, L.Y.1    Pisarri, T.E.2
  • 31
    • 0037447326 scopus 로고    scopus 로고
    • Activation of dopamine D2-like receptors attenuates pulmonary C-fiber hypersensitivity in rats
    • Lin YS, Gu Q, Lee LY. Activation of dopamine D2-like receptors attenuates pulmonary C-fiber hypersensitivity in rats. Am J Respir Crit Care Med 167: 1096-1101, 2003.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1096-1101
    • Lin, Y.S.1    Gu, Q.2    Lee, L.Y.3
  • 32
    • 66149119054 scopus 로고    scopus 로고
    • Sensitization of capsaicinsensitive lung vagal afferents by anandamide in rats: Role of transient receptor potential vanilloid 1 receptors
    • Lin YS, Lin RL, Bien MY, Ho CY, Kou YR. Sensitization of capsaicinsensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. J Appl Physiol 106: 1142-1152, 2009.
    • (2009) J Appl Physiol , vol.106 , pp. 1142-1152
    • Lin, Y.S.1    Lin, R.L.2    Bien, M.Y.3    Ho, C.Y.4    Kou, Y.R.5
  • 33
    • 77951957689 scopus 로고    scopus 로고
    • Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats
    • Lin YS, Hsu CC, Bien MY, Hsu HC, Weng HT, Kou YR. Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats. J Appl Physiol 108: 1293-1303, 2010.
    • (2010) J Appl Physiol , vol.108 , pp. 1293-1303
    • Lin, Y.S.1    Hsu, C.C.2    Bien, M.Y.3    Hsu, H.C.4    Weng, H.T.5    Kou, Y.R.6
  • 34
    • 0034999347 scopus 로고    scopus 로고
    • Role of vagal C-fiber afferents in the bronchomotor response to lactic acid in the newborn dog
    • Marantz MJ, Vincent SG, Fisher JT. Role of vagal C-fiber afferents in the bronchomotor response to lactic acid in the newborn dog. J Appl Physiol 90: 2311-2318, 2001.
    • (2001) J Appl Physiol , vol.90 , pp. 2311-2318
    • Marantz, M.J.1    Vincent, S.G.2    Fisher, J.T.3
  • 35
    • 29244463541 scopus 로고    scopus 로고
    • Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs
    • Mazzone SB, Mori N, Canning BJ. Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs. J Physiol 569: 559-573, 2005.
    • (2005) J Physiol , vol.569 , pp. 559-573
    • Mazzone, S.B.1    Mori, N.2    Canning, B.J.3
  • 36
    • 84862771013 scopus 로고    scopus 로고
    • Allergen and ozone exacerbate serotonin-induced increases in airway smooth muscle contraction in a model of childhood asthma
    • Moore BD, Hyde D, Miller L, Wong E, Frelinger J, Schelegle ES. Allergen and ozone exacerbate serotonin-induced increases in airway smooth muscle contraction in a model of childhood asthma. Respiration 83: 529-542, 2012.
    • (2012) Respiration , vol.83 , pp. 529-542
    • Moore, B.D.1    Hyde, D.2    Miller, L.3    Wong, E.4    Frelinger, J.5    Schelegle, E.S.6
  • 37
    • 37549037854 scopus 로고    scopus 로고
    • Activation of 5-hydroxytryptamine type 3 receptor-expressing C-fiber vagal afferents inhibits retrotrapezoid nucleus chemoreceptors in rats
    • Moreira TS, Takakura AC, Colombari E, Guyenet PG. Activation of 5-hydroxytryptamine type 3 receptor-expressing C-fiber vagal afferents inhibits retrotrapezoid nucleus chemoreceptors in rats. J Neurophysiol 98: 3627-3637, 2007.
    • (2007) J Neurophysiol , vol.98 , pp. 3627-3637
    • Moreira, T.S.1    Takakura, A.C.2    Colombari, E.3    Guyenet, P.G.4
  • 38
    • 34447526775 scopus 로고    scopus 로고
    • Roles of P2X receptors and Ca2 sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle
    • Oguma T, Ito S, Kondo M, Makino Y, Shimokata K, Honjo H, Kamiya K, Kume H. Roles of P2X receptors and Ca2 sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle. Clin Exp Allergy 37: 893-900, 2007.
    • (2007) Clin Exp Allergy , vol.37 , pp. 893-900
    • Oguma, T.1    Ito, S.2    Kondo, M.3    Makino, Y.4    Shimokata, K.5    Honjo, H.6    Kamiya, K.7    Kume, H.8
  • 39
    • 0030048988 scopus 로고    scopus 로고
    • Mechanism of action of ATP on canine pulmonary vagal C fibre nerve terminals
    • Pelleg A, Hurt CM. Mechanism of action of ATP on canine pulmonary vagal C fibre nerve terminals. J Physiol 490: 265-275, 1996.
    • (1996) J Physiol , vol.490 , pp. 265-275
    • Pelleg, A.1    Hurt, C.M.2
  • 40
    • 0020640688 scopus 로고
    • The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres
    • Petsche U, Fleischer E, Lembeck F, Handwerker HO. The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres. Brain Res 265: 233-240, 1983.
    • (1983) Brain Res , vol.265 , pp. 233-240
    • Petsche, U.1    Fleischer, E.2    Lembeck, F.3    Handwerker, H.O.4
  • 42
    • 13644262070 scopus 로고    scopus 로고
    • Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle
    • Rousseau E, Cloutier M, Morin C, Proteau S. Capsazepine, a vanilloid antagonist, abolishes tonic responses induced by 20-HETE on guinea pig airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 288: L460- L470, 2005.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Rousseau, E.1    Cloutier, M.2    Morin, C.3    Proteau, S.4
  • 43
    • 0037405253 scopus 로고    scopus 로고
    • Afferent vagal pathways mediating respiratory reflexes evoked by ROS in the lungs of anesthetized rats
    • Ruan T, Ho CY, Kou YR. Afferent vagal pathways mediating respiratory reflexes evoked by ROS in the lungs of anesthetized rats. J Appl Physiol 94: 1987-1998, 2003.
    • (2003) J Appl Physiol , vol.94 , pp. 1987-1998
    • Ruan, T.1    Ho, C.Y.2    Kou, Y.R.3
  • 44
    • 19444363110 scopus 로고    scopus 로고
    • Hyperthermia increases sensitivity of pulmonary C-fibre afferents in rats
    • Ruan T, Gu Q, Kou YR, Lee LY. Hyperthermia increases sensitivity of pulmonary C-fibre afferents in rats. J Physiol 565: 295-308, 2005.
    • (2005) J Physiol , vol.565 , pp. 295-308
    • Ruan, T.1    Gu, Q.2    Kou, Y.R.3    Lee, L.Y.4
  • 45
    • 21044442008 scopus 로고    scopus 로고
    • Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats
    • Ruan T, Lin YS, Lin KS, Kou YR. Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats. J Physiol 565: 563-578, 2005.
    • (2005) J Physiol , vol.565 , pp. 563-578
    • Ruan, T.1    Lin, Y.S.2    Lin, K.S.3    Kou, Y.R.4
  • 46
    • 33746720165 scopus 로고    scopus 로고
    • Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats
    • Ruan T, Lin YS, Lin KS, Kou YR. Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats. J Appl Physiol 101: 644-654, 2006.
    • (2006) J Appl Physiol , vol.101 , pp. 644-654
    • Ruan, T.1    Lin, Y.S.2    Lin, K.S.3    Kou, Y.R.4
  • 47
    • 0022519579 scopus 로고
    • Axonal transport of radiolabeled materials in afferent fibers of rabbit vagus nerve following supranodose vagotomy
    • Sato M, Yoshizaki K, Koyano H. Axonal transport of radiolabeled materials in afferent fibers of rabbit vagus nerve following supranodose vagotomy. Jpn J Physiol 36: 225-230, 1986.
    • (1986) Jpn J Physiol , vol.36 , pp. 225-230
    • Sato, M.1    Yoshizaki, K.2    Koyano, H.3
  • 48
    • 84861699183 scopus 로고    scopus 로고
    • Vagal afferents contribute to exacerbated airway responses following ozone and allergen challenge
    • Schelegle ES, Walby WF. Vagal afferents contribute to exacerbated airway responses following ozone and allergen challenge. Respir Physiol Neurobiol 181: 277-285, 2012.
    • (2012) Respir Physiol Neurobiol , vol.181 , pp. 277-285
    • Schelegle, E.S.1    Walby, W.F.2
  • 49
    • 0034813335 scopus 로고    scopus 로고
    • Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats
    • Schelegle ES, Alfaro MF, Putney L, Stovall M, Tyler N, Hyde DM. Effect of C-fiber-mediated, ozone-induced rapid shallow breathing on airway epithelial injury in rats. J Appl Physiol 91: 1611-1618, 2001.
    • (2001) J Appl Physiol , vol.91 , pp. 1611-1618
    • Schelegle, E.S.1    Alfaro, M.F.2    Putney, L.3    Stovall, M.4    Tyler, N.5    Hyde, D.M.6
  • 50
    • 34548504096 scopus 로고    scopus 로고
    • 12- Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1
    • Sexton A, McDonald M, Cayla C, Thiemermann C, Ahluwalia A. 12- Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1. FASEB J 21: 2695- 2703, 2007.
    • (2007) FASEB J , vol.21 , pp. 2695-2703
    • Sexton, A.1    McDonald, M.2    Cayla, C.3    Thiemermann, C.4    Ahluwalia, A.5
  • 52
    • 0022599761 scopus 로고
    • Axonal effects of capsaicin: An electrophysiological study
    • Such G, Jancsó G. Axonal effects of capsaicin: an electrophysiological study. Acta Physiol Hung 67: 53-63, 1986.
    • (1986) Acta Physiol Hung , vol.67 , pp. 53-63
    • Such, G.1    Jancsó, G.2
  • 53
    • 33748445549 scopus 로고    scopus 로고
    • Transduction mechanisms in airway sensory nerves
    • Taylor-Clark T, Undem BJ. Transduction mechanisms in airway sensory nerves. J Appl Physiol 101: 950-959, 2006.
    • (2006) J Appl Physiol , vol.101 , pp. 950-959
    • Taylor-Clark, T.1    Undem, B.J.2
  • 54
    • 0035940776 scopus 로고    scopus 로고
    • Evidence for the involvement of purinergic signalling in the control of respiration
    • Thomas T, Ralevic V, Bardini M, Burnstock G, Spyer KM. Evidence for the involvement of purinergic signalling in the control of respiration. Neuroscience 107: 481-490, 2001.
    • (2001) Neuroscience , vol.107 , pp. 481-490
    • Thomas, T.1    Ralevic, V.2    Bardini, M.3    Burnstock, G.4    Spyer, K.M.5
  • 57
    • 84860389749 scopus 로고    scopus 로고
    • TRPV1, TRPA1 and CB1 in the isolated vagus nerve-axonal chemosensitivity and control of neuropeptide release
    • Weller K, Reeh PW, Sauer SK. TRPV1, TRPA1, and CB1 in the isolated vagus nerve-axonal chemosensitivity and control of neuropeptide release. Neuropeptides 45: 391-400, 2011.
    • (2011) Neuropeptides , vol.45 , pp. 391-400
    • Weller, K.1    Reeh, P.W.2    Sauer, S.K.3
  • 58
    • 79952447457 scopus 로고    scopus 로고
    • TRPV1 channels in the nucleus of the solitary tract mediate thermal prolongation of the LCR in decerebrate piglets
    • Xia L, Bartlett D Jr, Leiter JC. TRPV1 channels in the nucleus of the solitary tract mediate thermal prolongation of the LCR in decerebrate piglets. Respir Physiol Neurobiol 176: 21-31, 2011.
    • (2011) Respir Physiol Neurobiol , vol.176 , pp. 21-31
    • Xia, L.1    Bartlett Jr., D.2    Leiter, J.C.3
  • 59
    • 59449105378 scopus 로고    scopus 로고
    • TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus
    • Yu S, Ouyang A. TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol 296: G255-G265, 2009.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Yu, S.1    Ouyang, A.2
  • 60
    • 84864768803 scopus 로고    scopus 로고
    • Activation of opioid -receptors, but not -or -receptors, switches pulmonary C-fiber-mediated rapid shallow breathing into an apnea in anesthetized rats
    • Zhang Z, Zhang C, Zhou M, Xu F. Activation of opioid -receptors, but not -or -receptors, switches pulmonary C-fiber-mediated rapid shallow breathing into an apnea in anesthetized rats. Respir Physiol Neurobiol 183: 211-217, 2012.
    • (2012) Respir Physiol Neurobiol , vol.183 , pp. 211-217
    • Zhang, Z.1    Zhang, C.2    Zhou, M.3    Xu, F.4
  • 61
    • 34250170568 scopus 로고    scopus 로고
    • Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists
    • Zhu LP, Ye DY, Tang Y. Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists. J Mol Model 13: 121-131, 2007.
    • (2007) J Mol Model , vol.13 , pp. 121-131
    • Zhu, L.P.1    Ye, D.Y.2    Tang, Y.3
  • 62
    • 84865119313 scopus 로고    scopus 로고
    • 8-OH-DPAT abolishes the pulmonary C-fiber-mediated apneic response to fentanyl largely via acting on 5HT1A receptors in the nucleus tractus solitarius
    • Zhuang J, Zhang Z, Zhang C, Xu F. 8-OH-DPAT abolishes the pulmonary C-fiber-mediated apneic response to fentanyl largely via acting on 5HT1A receptors in the nucleus tractus solitarius. Am J Physiol Regul Integr Comp Physiol 303: R449-R458, 2012.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.303
    • Zhuang, J.1    Zhang, Z.2    Zhang, C.3    Xu, F.4


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