Polymorphonuclear neutrophils in osteomyelitis: Link to osteoclast generation and bone resorption

European Journal of Inflammation

Volumn 10, Issue 3, 2012, Pages 413-426

  Gaida, M M ^a   Mayer, B ^a   Stegmaier, S ^a   Schirmacher, P ^a   Wagner, C ^b   Hänsch, G Maria ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b BG Trauma Center Ludwigshafen   (Germany)

Author keywords

Bone erosion; IL 8; Osteoclastogenesis; Osteomyelitis; Polymorphonuclear neutrophils

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CATHEPSIN K; CD14 ANTIGEN; COLONY STIMULATING FACTOR 1; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGEN EXPRESSION; ARTERY OCCLUSION; ARTICLE; BACTERIAL INFECTION; BONE ATROPHY; BONE BIOPSY; BONE DESTRUCTION; BONE EROSION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; EX VIVO STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; LEUKOCYTE ACTIVATION; LYMPHOCYTE; MACROPHAGE; MALE; MONOCYTE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; OSTEOCLAST; OSTEOMYELITIS; SOFT TISSUE INFECTION;

EID: 84873458096     PISSN: 1721727X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1721727X1201000317     Document Type: Article

References (40)

1. Irfan UM, Dawson DV, Bissada NF. Epidemiology of periodontal disease: a review and clinical perspectives. J Int Acad Periodontol 2001; 3:14-21.
2. Walsh NC, Gravallese EM. Bone loss in inflammatory arthritis: mechanisms and treatment strategies. Curr Opin Rheumatol 2004; 16:419-27. (Pubitemid 38803144)
3. Hunter DJ, Sambrook PN. Bone loss. Epidemiology of bone loss. Arthritis Res 2000; 2:441-5.
4. Walsh NC, Gravallese EM. Bone remodeling in rheumatic disease: a question of balance. Immunol Rev 2010; 233:301-12.
5. David JP, Mehic D, Bakiri L, Schilling AF, Mandic V, Priemel M, et al. Essential role of RSK2 in c-Fos-dependent osteosarcoma development. J Clin Invest 2005; 115:664-72. (Pubitemid 40322240)
6. Virk MS, Lieberman JR. Tumor metastasis to bone. Arthritis Res Ther 2007; 9(S)1:5.
7. Kingsley LA, Fournier PG, Chirgwin JM, Guise TA. Molecular biology of bone metastasis. Mol Cancer Ther 2007; 6:2609-17. (Pubitemid 350058141)
8. Hiatt WR, Nehler MR. Peripheral arterial disease. Adv Intern Med 2001; 47:89-110. (Pubitemid 33791975)
9. McDermott MM, Greenland P, Liu K, et al. Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment. JAMA 2001; 286:1599-606. (Pubitemid 33010284)
10. Caputo GM, Cavanagh PR, Ulbrecht JS, Gibbons GW, Karchmer AW. Assessment and management of foot disease in patients with diabetes. N Engl J Med 1994; 331:854-60.
11. Gaida MM, Bach ST, Gunther F, et al. Expression of Galectin-3 in Pancreatic Ductal Adenocarcinoma. Pathol Oncol Res 2012; 18:299-307.
12. Wagner C, Kondella K, Bernschneider T, Heppert V, Wentzensen A, Hansch GM. Post-traumatic osteomyelitis: analysis of inflammatory cells recruited into the site of infection. Shock 2003; 20:503-10.
13. Lakkakorpi PT, Vaananen HK. Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro. J Bone Miner Res 1991; 6:817-26.
14. Wagner C, Iking-Konert C, Hug F, et al. Cellular inflammatory response to persistent localized Staphylococcus aureus infection: phenotypical and functional characterization of polymorphonuclear neutrophils (PMN). Clin Exp Immunol 2006; 143:70-7.
15. Asagiri M, Sato K, Usami T, et al. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 2005; 202:1261-9. (Pubitemid 41586956)
16. Ishida Y, Denovan-Wright E, Hebb MO, Robertson HA. Amphetamine-induced Fos expression is evident in gamma-aminobutyric acid neurons in the globus pallidus and entopeduncular nucleus in rats treated with intrastriatal c-fos antisense oligodeoxynucleotides. Exp Neurol 2002; 175:275-81. (Pubitemid 34507928)
17. Yamashita T, Yao Z, Li F, et al. NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem 2007; 282:18245-53. (Pubitemid 47100255)
18. Ikeda F, Nishimura R, Matsubara T, Hata K, Reddy SV, Yoneda T. Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity. J Immunol 2006; 177:2384-90. (Pubitemid 44200999)
19. Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, Einhorn TA. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res 2008; 87:107-18.
20. Witko-Sarsat V, Rieu P, Descamps-Latscha B, Lesavre P, Halbwachs-Mecarelli L. Neutrophils: molecules, functions and pathophysiological aspects. Lab Invest 2000; 80:617-53.
21. Lew DP, Waldvogel FA. Osteomyelitis. Lancet 2004; 364:369-79.
22. Wagner C, Heck D, Lautenschlager K, et al. T lymphocytes in implant-associated posttraumatic osteomyelitis: Identification of cytotoxic T effector cells at the site of infection. Shock 2006; 25:241-26.
23. Iking-Konert C, Vogt S, Radsak M, Wagner C, Hansch GM, Andrassy K. Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int 2001; 60:2247-62. (Pubitemid 33070467)
24. Iking-Konert C, Ostendorf B, Sander O, et al. Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells. Ann Rheum Dis 2005; 64:1436-42. (Pubitemid 41623854)
25. Altstaedt J, Kirchner H, Rink L. Cytokine production of neutrophils is limited to interleukin-8. Immunology 1996; 89:563-8. (Pubitemid 26419658)
26. Bendre MS, Montague DC, Peery T, Akel NS, Gaddy D, Suva LJ. Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. Bone 2003; 33:28-37. (Pubitemid 36952685)
27. Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397:315-23.
28. Seta N, Okazaki Y, Kuwana M. Human circulating monocytes can express receptor activator of nuclear factor-kappaB ligand and differentiate into functional osteoclasts without exogenous stimulation. Immunol Cell Biol 2008; 86:453-9. (Pubitemid 351948219)
29. Kim K, Kim JH, Lee J, et al. MafB negatively regulates RANKL-mediated osteoclast differentiation. Blood 2007; 109:3253-9. (Pubitemid 46572510)
30. Smink JJ, Begay V, Schoenmaker T, Sterneck E, de Vries TJ, Leutz A. Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB. EMBO J 2009; 28:1769-81.
31. Kim JH, Jin HM, Kim K, et al. The mechanism of osteoclast differentiation induced by IL-1. J Immunol 2009; 183:1862-70.
32. Mansky KC, Marfatia K, Purdom GH, Luchin A, Hume DA, Ostrowski MC. The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts. J Leukoc Biol 2002; 71:295-303.
33. Sharma SM, Bronisz A, Hu R, et al. MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. J Biol Chem 2007; 282:15921-9. (Pubitemid 47093311)
34. Scheven BA, Milne JS, Hunter I, Robins SP. Macrophage-inflammatory protein-1 alpha regulates preosteoclast differentiation in vitro. Biochem Biophys Res Commun 1999; 254:773-8. (Pubitemid 29290544)
35. Choi SJ, Cruz JC, Craig F, et al. Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma. Blood 2000; 96:671-5. (Pubitemid 30463390)
36. Hemingway F, Taylor R, Knowles HJ, Athanasou NA. RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II. Bone 2011; 48:938-44.
37. Jeffcoate WJ, Game F, Cavanagh PR. The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes. Lancet 2005; 366:2058-61. (Pubitemid 41773381)
38. Iking-Konert C, Cseko C, Wagner C, Stegmaier S, Andrassy K, Hansch GM. Transdifferentiation of polymorphonuclear neutrophils: acquisition of CD83 and other functional characteristics of dendritic cells. J Mol Med (Berl) 2001; 79:464-74. (Pubitemid 32757472)
39. Cross A, Barnes T, Bucknall RC, Edwards SW, Moots RJ. Neutrophil apoptosis in rheumatoid arthritis is regulated by local oxygen tensions within joints. J Leukoc Biol 2006; 80:521-8. (Pubitemid 44835785)
40. Chakravarti A, Raquil MA, Tessier P, Poubelle PE. Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption. Blood 2009; 114:1633-44.