Analytic Evaluation of a Human ELISA Kit for Measurement of Inhibin B in Rat Samples

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 98, Issue 1, 2013, Pages 4-16

  Coulson, Michelle ^a   Bickerton, Sue ^a   Betts, Catherine J ^a   Jacobsen, Matt ^a   Stewart, Jane ^a   Chapin, Robert E ^b   Reagan, William J ^b   Alvey, James ^b   Erdos, Zoltan ^c   Saldutti, Louise Parks ^c   Sonee, Manisha ^d   Bogdan, Nancy ^d   Singer, Monica ^d   Vinken, Petra ^e   Barlow, Valerie ^f   Czajkowski, Karen ^f   Kim, James H ^g  

^a ASTRAZENECA   (United Kingdom)

^b PFIZER INC   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^e JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^f SANOFI   (France)

^g ILSI HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE   (United States)

Author keywords

biomarker; ELISA; fertility; inhibin B; Rat; testes; toxicity; validation

Indexed keywords

INHIBIN B;

ARTICLE; BLOOD SAMPLING; CALCULATION; ELISA KIT; FREEZE THAWING; HORMONE BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; SPRAGUE DAWLEY RAT; TESTIS DISEASE; WISTAR RAT;

ANIMALS; BIOLOGICAL ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREEZING; HUMANS; INHIBINS; MALE; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REFERENCE VALUES; SERUM;

EID: 84873457536     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.21047     Document Type: Article

References (9)

1. Adamopoulos DA, Koukkou EG. 2010. Value of FSH and inhibin B measurements in the diagnosis of azoospermia-a clinician's overview. Int J Androl 33:e109-e113.
2. Kalra B, Kumar A, Patel K, Patel A, Khosravi MJ. 2010. Development of a second generation inhibin B ELISA. J Immunol Methods 362:22-31.
3. Lockwood G. 2004. The diagnostic value of inhibin in infertility evaluation. Semin Reprod Med 22:195-208.
4. Ludlow H, Muttukrishna S, Hyyonen M, Groome NP. 2008. Development of a new antibody to the human inhibin/activin B subunit and its application to improved inhibin B ELISAs. J.Immunol Methods 329:102-111.
5. Mabeck LM, Jensen MS, Toft G, Thulstrup M, Andersson M, Jensen TK, Giwercman A, Olsen J, Bonde JP, and the Danish First Pregnancy Planners Team. 2005. Fecundability according to male serum inhibin B-a prospective study among first pregnancy planners. Hum Reprod 20:2909-2915.
6. Makanji Y, Harrison CA, Robertson, DM. 2011. Feedback regulation of inhibins A and B of the pituitary secretion of follicle stimulating hormone. Vitam Horm 85:299-321.
7. Meachem SJ, Nieschlag E, Simoni M. 2001. Inhibin B in male reproduction: pathophysiology and clinical relevance. Eur J Endocrinol 145:561-571.
8. Stewart J, Turner KJ. 2005. Inhibin B as a potential biomarker of testicular toxicity. Cancer Biomark 1:75-91.
9. Von Eckerdstein S, Simoni M, Bergmann M, Weinbauer GF, Gassner P, Schepers AG, Nieschlag E. 1999. Serum inhibin B in combination with serum follicle stimulating hormone (FSH) is a more sensitive marker than serum FSH alone for impaired spermatogenesis in men, but cannot predict the presence of sperm in testicular tissue samples. J Clin Endocrinol Metab 84:2496-2501.