Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 6, 2013, Pages 2135-2139

  Longo, Liam M ^a   Lee, Jihun ^a   Blaber, Michael ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Protein evolution; Protein simplification

Indexed keywords

ALPHA AMINO ACID; CARBON; FIBROBLAST GROWTH FACTOR 1; ISOLEUCINE; LEUCINE; PHENYLALANINE; PREBIOTIC AGENT; VALINE;

ACIDIFICATION; ACIDITY; AMINO ACID COMPOSITION; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; HALOPHILE; IONIC STRENGTH; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; STATIC ELECTRICITY; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; BIOGENESIS; BIOPHYSICAL PHENOMENA; CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN FOLDING; PROTEIN STABILITY; PROTEINS; STATIC ELECTRICITY;

EID: 84873451688     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1219530110     Document Type: Article

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