Comparative study of the efficacy and tolerability of a unique topical scar product vs white petrolatum following shave biopsies

Journal of Drugs in Dermatology

Volumn 12, Issue 1, 2013, Pages 86-90

  Kircik, Leon H ^a,b,c  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Physicians Skin Care PLLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERMATOLOGICAL AGENT; WHITE PETROLATUM;

ADULT; AGED; ARTICLE; BIOPSY TECHNIQUE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; DRUG EFFICACY; DRUG TOLERABILITY; EPITHELIZATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; PATIENT SATISFACTION; PHOTOGRAPHY; RATING SCALE; SCAR; SHAVE BIOPASY;

ADULT; AGED; BIOPSY; CENTELLA; CICATRIX; DIAGNOSTIC SELF EVALUATION; DOUBLE-BLIND METHOD; EMOLLIENTS; FEMALE; GELS; HUMANS; MALE; MIDDLE AGED; PETROLATUM; PLANT EXTRACTS; PRURITUS; PYRANS; REGIONAL BLOOD FLOW; SENSATION; SKIN; SKIN PIGMENTATION; VASODILATOR AGENTS; YOUNG ADULT;

EID: 84873447754     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Owings MF, Kozak LJ. Ambulatory and inpatient procedures in the United States, 1996. Vital Health Stat 13. 1998;(139):1-119.
2. Morganroth P, Wilmot AC, Miller C. Over-the-counter scar products for postsurgical patients: disparities between online advertised benefits and evidence regarding efficacy. J Am Acad Dermatol. 2009;61(6):e31-e47.
3. Widgerow AD, Chait LA, Stals PJ, Stals R, Candy G. Multimodality scar management program. Aesthetic Plast Surg. 2009;33(4):533-543.
4. Bayat A, McGrouther DA, Ferguson MW. Skin scarring. BMJ. 2003;326(7380):88-92.
5. 2011 Plastic Surgery Statistics Report. American Society of Plastic Surgeons Web site. http://www.plasticsurgery.org/Documents/news-resources/ statistics/2011-statistics/2011-Stats-Full-Report.pdf. Accessed June 4, 2012.
6. Chang CC, Kuo YF, Chiu HC, Lee JL, Wong TW, Jee SH. Hydration, not silicone, modulates the effects of keratinocytes on fibroblasts. J Surg Res. 1995;59(6):705-711.
7. Mustoe TA. Evolution of silicone therapy and mechanism of action in scar management. Aesthetic Plast Surg. 2008;32(1):82-92.
8. Harrison CA, Gossiel F, Bullock AJ, Sun T, Blumsohn A, Mac Neil S. Investigation of keratinocyte regulation of collagen I synthesis by dermal fibroblasts in a simple in vitro model. Br J Dermatol. 2006;154(3):401-410.
9. Nickoloff BJ, Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol. 1994;30(4):535-546.
10. Widgerow AD, Chait LA, Stals R, Stals PJ. New innovations in scar management. Aesthetic Plast Surg. 2000;24(3):227-234.
11. Weber L, Meigel WN, Spier W. Collagen polymorphism in pathologic human scars. Arch Dermatol Res. 1978;261(1):63-71.
12. Bailey AJ, Bazin S, Sims TJ, Le Lous M, Nicoletis C, Delaunay A. Characterization of the collagen of human hypertrophic and normal scars. Biochim Biophys Acta. 1975;405(2):412-421.
13. Bonte F, Dumas M, Chaudagne C, Meybeck A. Influence of asiatic acid, madecassic acid and asiaticoside on human collagen I synthesis. Planta Med. 1994;60(2):133-135.
14. Maquart FX, Bellon G, Gillery P, Wegrowski Y, Borel JP. Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica. Connect Tissue Res. 1990;24(2):107-120.
15. Juolin X, Shao-Hai Q, Tian-Zeng L, et al. Effect of asiaticoside on hypertrophic scar in the rabbit ear model. J Cutan Pathol. 2009;36(2):234-239.
16. de la Puerta R, Ruiz Gutierrez V, Hoult JR. Inhibition of leukocyte 5-lipoxygenase by phenols from virgin olive oil. Biochem Pharmacol. 1999;57(4):445-449.
17. Visioli F, Bellosta S, Galli C. Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. Life Sci. 1998;62(6):541-546.
18. Widgerow AD. Cellular/extracellular matrix cross-talk in scar evolution and control. Wound Repair Regen. 2011;19(2):117-133.