Effect of didrovaltrate on l-calcium current in rabbit ventricular myocytes

Journal of Traditional Chinese Medicine

Volumn 32, Issue 3, 2012, Pages 442-445

  Xie, Qiang ^a   Li, Weihua ^a   Huang, Zhengrong ^a   Zhang, Ziguan ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

Author keywords

Calcium channels, L Type; Cardiac; Didrovaltrate; Myocytes; Patch clamp techniques

Indexed keywords

CALCIUM; DIDROVALTRATE; CALCIUM CHANNEL L TYPE; HERBACEOUS AGENT; IRIDOID; VALERIAN;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; DRUG EFFECT; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART VENTRICLE; MALE; NONHUMAN; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; HALF-ACTIVATION VOLTAGE; HEART DEPOLARIZATION; SLOPE FACTOR; STEADY STATE; WHOLE CELL PATCH CLAMP; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; ELECTROPHYSIOLOGY; METABOLISM; RABBIT;

ANIMALS; CALCIUM; CELLS, CULTURED; DRUGS, CHINESE HERBAL; ELECTROPHYSIOLOGICAL PHENOMENA; FEMALE; HEART VENTRICLES; IRIDOIDS; MALE; MYOCYTES, CARDIAC; RABBITS; VALERIAN;

MLCS; MLOWN;

EID: 84873420235     PISSN: 02552922     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0254-6272(13)60052-7     Document Type: Article

References (13)

1. Houghton P J. The scientific basis for the reputed activity of valerian. J Pharm Pharmacol 1999; 51(5): 505-512.
2. Hendriks H, Bos R, Allersma D P, Malingre T M, Koster A S. Pharmacological screening of valerenal and some other components of essential oil of valeriana officinalis. Planta Med 1981(1); 42: 62-68.
3. Ortiz J G, Nieves-Natal J, Chavez P. Effects of valeriana officinalis extracts on [3H] flunitrazeparm binding, synaptosomal [3H] GABA uptake, and hippocampal [3H] GABA release. Neurochem Res 1999; 24(11): 1373-1378.
4. Houghton P J. The biological activity of valerian and related plants. J Ethnopharmacol 1988; 22(2): 121-142.
5. Zhang B H, Meng H, Wang T, Dai Y C, Shen J, Tao C. Effect of Valeriana officinalis L extract on cardiovascular system. Yao Xue Xue Bao 1982; 17(5): 382-384.
6. Wang Y L, Xu S G, Fan S F. Electrophysiological studies on the antiarrhythmic effect of the water extract of valerian. Zhonghua Xin Xue Guan Bing Za Zhi 1979; 7(4): 275-282.
7. Tatgat J. How to isolate cardiac myocytes. Cardiovasc Res 1994; 28(2): 280-283.
8. Mcdonald T F, Pelzer S, Trautwein W, Pelzer D J. Regulation andmodulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev 1994; 74(2): 365-507.
9. Bean B P. Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology. J Gen Physiol 1985; 86(1): 1-30.
10. Carmeliet E. Cardiac ionic currents and acute ischemia: from channels to arrhythmias. Physiol Rev 1999; 79(3): 917-1017.
11. Upton R. Valeriana officinalis. J Altern Complement Med 2001; 7(1): 15-17.
12. Hadley S, Petry J J. Valerian. Am Fam Physician 2003; 67 (8): 1755-1758.
13. Barrett B, Kiefer D, Rabago D. Assessing the risks and benefits of herbal medicine: an overview of scientific evidence. Altern Ther Health Med 1999; 5(4): 40-49.