A multicenter, randomized, double-blind clinical trial of combination therapy with Anbainuo, a novel recombinant human TNFRII:Fc fusion protein, plus methotrexate versus methotrexate alone or Anbainuo alone in Chinese patients with moderate to severe rheumatoid arthritis

Clinical Rheumatology

Volumn 32, Issue 1, 2013, Pages 99-108

  Chen, Xiao Xiang ^a   Dai, Qing ^a   Huang, An Bin ^b   Wu, Hua Xiang ^c   Zhao, Dong Bao ^d   Li, Xing Fu ^e   Hu, Shao Xian ^f   Yang, Nan Ping ^g   Tao, Yi ^h   Xu, Jian Hua ⁱ   Jiang, Lin Di ^j   Bao, Chun De ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Affiliated to Tongji University   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d SECOND MILITARY MEDICAL UNIVERSITY   (China)

^e SHANDONG UNIVERSITY   (China)

^f TONGJI UNIVERSITY   (China)

^g SICHUAN UNIVERSITY   (China)

^h Affiliated to Zhongshan Medical University   (China)

ⁱ ANHUI MEDICAL UNIVERSITY   (China)

^j FUDAN UNIVERSITY   (China)

more..

Author keywords

Methotrexate; Rheumatoid arthritis; TNF receptor II: Fc fusion protein

Indexed keywords

ANBAINUO; ANTIRHEUMATIC AGENT; HYBRID PROTEIN; METHOTREXATE; RECOMBINANT TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ABDOMINAL DISCOMFORT; ADULT; ARTHRALGIA; ARTICLE; CHILL; CHINESE; COMBINATION CHEMOTHERAPY; CONJUNCTIVITIS; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG SAFETY; FECES; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; GINGIVITIS; HEADACHE; HEMOGLOBIN BLOOD LEVEL; HERPES ZOSTER; HUMAN; INJECTION SITE REACTION; KIDNEY FUNCTION TEST; LEUKOCYTE COUNT; LIVER FUNCTION TEST; LUNG INFECTION; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MORBIDITY; MULTICENTER STUDY; NAUSEA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; RHEUMATOID ARTHRITIS; SIDE EFFECT; THROMBOCYTE COUNT; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION; VOMITING;

ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; HYPERALGESIA; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; JOINTS; MALE; METHOTREXATE; MIDDLE AGED; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RECOMBINANT FUSION PROTEINS; SEVERITY OF ILLNESS INDEX;

EID: 84873410858     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-012-2096-z     Document Type: Article

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