-
1
-
-
80054767730
-
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: Roles for fumarate in KEAP1 succination and Nrf2 signaling
-
22014577 10.1016/j.ccr.2011.09.006 1:CAS:528:DC%2BC3MXhtlKrtrfM
-
Adam J, Hatipoglu E, O'Flaherty L, Ternette N, Sahgal N, Lockstone H, Baban D, Nye E, Stamp GW, Wolhuter K, Stevens M, Fischer R, Carmeliet P, Maxwell PH, Pugh CW, Frizzell N, Soga T, Kessler BM, El-Bahrawy M, Ratcliffe PJ, Pollard PJ (2011) Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell 20:524-537
-
(2011)
Cancer Cell
, vol.20
, pp. 524-537
-
-
Adam, J.1
Hatipoglu, E.2
O'Flaherty, L.3
Ternette, N.4
Sahgal, N.5
Lockstone, H.6
Baban, D.7
Nye, E.8
Stamp, G.W.9
Wolhuter, K.10
Stevens, M.11
Fischer, R.12
Carmeliet, P.13
Maxwell, P.H.14
Pugh, C.W.15
Frizzell, N.16
Soga, T.17
Kessler, B.M.18
El-Bahrawy, M.19
Ratcliffe, P.J.20
Pollard, P.J.21
more..
-
2
-
-
79953311652
-
Biomarkers and drug targets in addiction and obesity
-
Alguacil LF, Stucchi P, del Olmo N, Herradón G, Ruiz-Gayo M (2010) Biomarkers and drug targets in addiction and obesity. Eur J Clin Pharmacol 66:S85
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 85
-
-
Alguacil, L.F.1
Stucchi, P.2
Del Olmo, N.3
Herradón, G.4
Ruiz-Gayo, M.5
-
3
-
-
79953304305
-
Identification of new drug targets and biomarkers related to obesity and eating disorders: An approach based on reward deficit and addiction
-
21375484 10.2174/138161211795164158 1:CAS:528:DC%2BC3MXlsVKltrw%3D
-
Alguacil LF, Salas E, González-Martín C (2011a) Identification of new drug targets and biomarkers related to obesity and eating disorders: an approach based on reward deficit and addiction. Curr Pharm Des 17:462-470
-
(2011)
Curr Pharm des
, vol.17
, pp. 462-470
-
-
Alguacil, L.F.1
Salas, E.2
González-Martín, C.3
-
4
-
-
85081459051
-
Fumarate hydratase is upregulated in the striatum of animals with spontaneous and diet-induced inhibition of psychostimulant reward
-
Washington, DC: Society for Neuroscience, Online
-
Alguacil LF, Stucchi P, Salas E, del Olmo N, Herradón G, González-Martín C, Ruiz-Gayo M (2011b) Fumarate hydratase is upregulated in the striatum of animals with spontaneous and diet-induced inhibition of psychostimulant reward. Neuroscience Meeting Planner 688.11/JJ11 Washington, DC: Society for Neuroscience, Online
-
(2011)
Neuroscience Meeting Planner 688.11/JJ11
-
-
Alguacil Lf, S.1
-
5
-
-
0034530331
-
Reward deficiency syndrome: A biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors
-
Blum K, Braverman ER, Holder JM, Lubar JF, Monastra VJ, Miller D, Lubar JO, Chen TJ, Comings DE. (2000). Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors. J Psychoactive Drugs 32(Suppl:i-iv):1-112
-
(2000)
J Psychoactive Drugs
, vol.32
, Issue.SUPPL. I-IV
, pp. 1-112
-
-
Blum, K.1
Braverman, E.R.2
Holder, J.M.3
Lubar, J.F.4
Monastra, V.J.5
Miller, D.6
Lubar, J.O.7
Chen, T.J.8
Comings, D.E.9
-
6
-
-
67349100994
-
Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction
-
19393250 10.1016/j.neuropharm.2009.04.005
-
Castillo C, Morales L, Alguacil LF, Salas E, Garrido E, Alonso E, Pérez-García C (2009a) Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. Neuropharmacology 57:41-48
-
(2009)
Neuropharmacology
, vol.57
, pp. 41-48
-
-
Castillo, C.1
Morales, L.2
Alguacil, L.F.3
Salas, E.4
Garrido, E.5
Alonso, E.6
Pérez-García, C.7
-
7
-
-
85081459108
-
Análisis del proteoma de la corteza cerebral de ratas con diferente vulnerabilidad a la adicción a la cocaína
-
Castillo C, Morales L, Salas E, Alguacil LF, Pérez-García C (2009b) Análisis del proteoma de la corteza cerebral de ratas con diferente vulnerabilidad a la adicción a la cocaína. Abstracts XIII Meeting SENC: 149
-
(2009)
Abstracts XIII Meeting SENC
, pp. 149
-
-
Castillo C, M.1
-
8
-
-
57049145380
-
Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat
-
19045945 10.1037/a0013111
-
Davis JF, Tracy AL, Schurdak JD, Tschöp MH, Lipton JW, Clegg DJ, Benoit SC (2008) Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behav Neurosci 122:1257-1263
-
(2008)
Behav Neurosci
, vol.122
, pp. 1257-1263
-
-
Davis, J.F.1
Tracy, A.L.2
Schurdak, J.D.3
Tschöp, M.H.4
Lipton, J.W.5
Clegg, D.J.6
Benoit, S.C.7
-
9
-
-
33646431129
-
Molecular and biochemical investigations in fumarase deficiency
-
16510303 10.1016/j.ymgme.2006.01.007 1:CAS:528:DC%2BD28Xks1WrtrY%3D
-
Deschauer M, Gizatullina Z, Schulze A, Pritsch M, Knöppel C, Knape M, Zierz S, Gellerich FN (2006) Molecular and biochemical investigations in fumarase deficiency. Mol Genet Metab 88:146-152
-
(2006)
Mol Genet Metab
, vol.88
, pp. 146-152
-
-
Deschauer, M.1
Gizatullina, Z.2
Schulze, A.3
Pritsch, M.4
Knöppel, C.5
Knape, M.6
Zierz, S.7
Gellerich, F.N.8
-
10
-
-
0026631765
-
Glucose utilization and insulin action in adult rats submitted to prolonged food restriction
-
Escrivá F, Rodríguez C, Cacho J, Álvarez C, Portha B, Pascual-Leone AM (1992) Glucose utilization and insulin action in adult rats submitted to prolonged food restriction. Am J Physiol Endocrinol Metab 263:E1-E7
-
(1992)
Am J Physiol Endocrinol Metab
, vol.263
-
-
Escrivá, F.1
Rodríguez, C.2
Cacho, J.3
Álvarez, C.4
Portha, B.5
Pascual-Leone, A.M.6
-
11
-
-
33751181010
-
Undernutrition does not alter the activation of β-cell neogenesis and replication in adult rats after partial pancreotectomy
-
16757552 10.1152/ajpendo.00638.2005
-
Fernández E, Martín MA, Fajardo S, Bailbé D, Gangnerau MN, Portha B, Escrivá F, Serradas P, Alvarez C (2006) Undernutrition does not alter the activation of β-cell neogenesis and replication in adult rats after partial pancreotectomy. Am J Physiol Endocrinol Metab 291:E913-E921
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Fernández, E.1
Martín, M.A.2
Fajardo, S.3
Bailbé, D.4
Gangnerau, M.N.5
Portha, B.6
Escrivá, F.7
Serradas, P.8
Alvarez, C.9
-
12
-
-
23044502489
-
Maternal food restriction enhances insulin-induced GLUT-4 translocation and insulin signaling pathway in skeletal muscle from suckling rats
-
15905322 10.1210/en.2004-1658 1:CAS:528:DC%2BD2MXntVaitbo%3D
-
Gavete ML, Martín MA, Alvarez C, Escrivá F (2005) Maternal food restriction enhances insulin-induced GLUT-4 translocation and insulin signaling pathway in skeletal muscle from suckling rats. Endocrinology 146:3368-3378
-
(2005)
Endocrinology
, vol.146
, pp. 3368-3378
-
-
Gavete, M.L.1
Martín, M.A.2
Alvarez, C.3
Escrivá, F.4
-
13
-
-
0026019683
-
Specificity in the projection patterns of accumbal core and shell in the rat
-
2057066 10.1016/0306-4522(91)90202-Y 1:STN:280:DyaK3M3nvFSitw%3D%3D
-
Heimer L, Zahm DS, Churchill L, Kalivas PW, Wohltmann C (1991) Specificity in the projection patterns of accumbal core and shell in the rat. Neuroscience 41:89-125
-
(1991)
Neuroscience
, vol.41
, pp. 89-125
-
-
Heimer, L.1
Zahm, D.S.2
Churchill, L.3
Kalivas, P.W.4
Wohltmann, C.5
-
14
-
-
71649105996
-
Early undernutrition increases glycogen content and reduces the activated forms of GSK3, AMPK, p38 MAPK and JNK in the cerebral cortex of suckling rats
-
19840222 10.1111/j.1471-4159.2009.06434.x
-
Lizárraga-Mollinedo E, Fernández-Millán E, de Miguel-Santos L, Martínez-Honduvilla C, Alvarez C, Escrivá F (2010) Early undernutrition increases glycogen content and reduces the activated forms of GSK3, AMPK, p38 MAPK and JNK in the cerebral cortex of suckling rats. J Neurochem 112:123-133
-
(2010)
J Neurochem
, vol.112
, pp. 123-133
-
-
Lizárraga-Mollinedo, E.1
Fernández-Millán, E.2
De Miguel-Santos, L.3
Martínez-Honduvilla, C.4
Alvarez, C.5
Escrivá, F.6
-
15
-
-
84860521436
-
Early undernutrition induces glucagon resistance and insulin hypersensitivity in the liver of suckling rats
-
22338073 10.1152/ajpendo.00495.2011
-
Lizárraga-Mollinedo E, Fernández-Millán E, de Toro MJ, Martínez-Honduvilla CJ, Escrivá F, Alvarez C (2012) Early undernutrition induces glucagon resistance and insulin hypersensitivity in the liver of suckling rats. Am J Physiol Endocrinol Metab 302:E1070-E1077
-
(2012)
Am J Physiol Endocrinol Metab
, vol.302
-
-
Lizárraga-Mollinedo, E.1
Fernández-Millán, E.2
De Toro, M.J.3
Martínez-Honduvilla, C.J.4
Escrivá, F.5
Alvarez, C.6
-
16
-
-
0030896319
-
Insulin secretion in adult rats than had experienced different underfeeding patterns during their development
-
Martín MA, Alvarez C, Goya L, Portha B, Pascual-Leone AM (1997) Insulin secretion in adult rats than had experienced different underfeeding patterns during their development. Am J Physiol Endocrinol Metab 272:E634-E640
-
(1997)
Am J Physiol Endocrinol Metab
, vol.272
-
-
Martín, M.A.1
Alvarez, C.2
Goya, L.3
Portha, B.4
Pascual-Leone, A.M.5
-
17
-
-
79958729718
-
Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase
-
21498518 10.1074/jbc.M110.214452 1:CAS:528:DC%2BC3MXntlOktLs%3D
-
Mescam M, Vinnakota KC, Beard DA (2011) Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase. J Biol Chem 286:21100-21109
-
(2011)
J Biol Chem
, vol.286
, pp. 21100-21109
-
-
Mescam, M.1
Vinnakota, K.C.2
Beard, D.A.3
-
18
-
-
9244252489
-
Inhibition of hepatic gluconeogenesis and enhanced glucose uptake contribute to the development of hypoglycemia in mice bearing interleukin-1beta-secreting tumor
-
15297440 10.1210/en.2004-0323 1:CAS:528:DC%2BD2cXptVyhu7w%3D
-
Metzger S, Nusair S, Planer D, Barash V, Pappo O, Shilyansky J, Chajek-Shaul T (2004) Inhibition of hepatic gluconeogenesis and enhanced glucose uptake contribute to the development of hypoglycemia in mice bearing interleukin-1beta-secreting tumor. Endocrinology 145:5150-5156
-
(2004)
Endocrinology
, vol.145
, pp. 5150-5156
-
-
Metzger, S.1
Nusair, S.2
Planer, D.3
Barash, V.4
Pappo, O.5
Shilyansky, J.6
Chajek-Shaul, T.7
-
19
-
-
84860528157
-
Shift of circadian feeding pattern by high-fat diets is coincident with reward deficits in obese mice
-
22570696 10.1371/journal.pone.0036139 1:CAS:528:DC%2BC38XnsVGhtro%3D
-
Morales L, Del Olmo N, Valladolid-Acebes I, Fole A, Cano V, Merino B, Stucchi P, Ruggieri D, López L, Alguacil LF, Ruiz-Gayo M (2012) Shift of circadian feeding pattern by high-fat diets is coincident with reward deficits in obese mice. PLoS One 7:e36139
-
(2012)
PLoS One
, vol.7
, pp. 36139
-
-
Morales, L.1
Del Olmo, N.2
Valladolid-Acebes, I.3
Fole, A.4
Cano, V.5
Merino, B.6
Stucchi, P.7
Ruggieri, D.8
López, L.9
Alguacil, L.F.10
Ruiz-Gayo, M.11
-
20
-
-
77956503391
-
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism
-
20660115 10.1093/hmg/ddq305
-
O'Flaherty L, Adam J, Heather LC, Zhdanov AV, Chung YL, Miranda MX, Croft J, Olpin S, Clarke K, Pugh CW, Griffiths J, Papkovsky D, Ashrafian H, Ratcliffe PJ, Pollard PJ (2010) Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. Hum Mol Genet 19:3844-3851
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3844-3851
-
-
O'Flaherty, L.1
Adam, J.2
Heather, L.C.3
Zhdanov, A.V.4
Chung, Y.L.5
Miranda, M.X.6
Croft, J.7
Olpin, S.8
Clarke, K.9
Pugh, C.W.10
Griffiths, J.11
Papkovsky, D.12
Ashrafian, H.13
Ratcliffe, P.J.14
Pollard, P.J.15
-
21
-
-
0014059118
-
An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study
-
10976232 10.1083/jcb.32.2.415 1:CAS:528:DyaF2sXot1CjsQ%3D%3D
-
Sottocasa GL, Kuylenstierna B, Ernster L, Bergstrand A (1967) An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J Cell Biol 32:415-438
-
(1967)
J Cell Biol
, vol.32
, pp. 415-438
-
-
Sottocasa, G.L.1
Kuylenstierna, B.2
Ernster, L.3
Bergstrand, A.4
-
22
-
-
68549122792
-
Novel role of fumarate metabolism in dahl-salt sensitive hypertension
-
19546378 10.1161/HYPERTENSIONAHA.109.129528 1:CAS:528: DC%2BD1MXosFWitb0%3D
-
Tian Z, Liu Y, Usa K, Mladinov D, Fang Y, Ding X, Greene AS, Cowley AW Jr, Liang M (2009) Novel role of fumarate metabolism in dahl-salt sensitive hypertension. Hypertension 54:255-260
-
(2009)
Hypertension
, vol.54
, pp. 255-260
-
-
Tian, Z.1
Liu, Y.2
Usa, K.3
Mladinov, D.4
Fang, Y.5
Ding, X.6
Greene, A.S.7
Cowley, Jr.A.W.8
Liang, M.9
-
23
-
-
0025666345
-
Prenatal protein malnutrition alters response to reward in adult rats
-
2127961 10.1016/0031-9384(90)90210-U 1:CAS:528:DyaK3MXhsVWqurg%3D
-
Tonkiss J, Shukitt-Hale B, Formica RN, Rocco FJ, Galler JR (1990) Prenatal protein malnutrition alters response to reward in adult rats. Physiol Behav 48:675-80
-
(1990)
Physiol Behav
, vol.48
, pp. 675-680
-
-
Tonkiss, J.1
Shukitt-Hale, B.2
Formica, R.N.3
Rocco, F.J.4
Galler, J.R.5
-
24
-
-
29744465124
-
Perinatal protein malnutrition enhances rewarding cocaine properties in adult rats
-
16226384 10.1016/j.neuroscience.2005.08.055 1:CAS:528: DC%2BD28XhsFGqsQ%3D%3D
-
Valdomero A, Bussolino DF, Orsingher OA, Cuadra GR (2006) Perinatal protein malnutrition enhances rewarding cocaine properties in adult rats. Neuroscience 137:221-229
-
(2006)
Neuroscience
, vol.137
, pp. 221-229
-
-
Valdomero, A.1
Bussolino, D.F.2
Orsingher, O.A.3
Cuadra, G.R.4
-
25
-
-
36649018792
-
Increased rewarding properties of morphine in perinatally protein-malnourished rats
-
17935891 10.1016/j.neuroscience.2007.09.006 1:CAS:528:DC%2BD2sXhsVWjtLjE
-
Valdomero A, Velazquez EE, de Olmos S, de Olmos JS, Orsingher OA, Cuadra GR (2007) Increased rewarding properties of morphine in perinatally protein-malnourished rats. Neuroscience 150:449-458
-
(2007)
Neuroscience
, vol.150
, pp. 449-458
-
-
Valdomero, A.1
Velazquez, E.E.2
De Olmos, S.3
De Olmos, J.S.4
Orsingher, O.A.5
Cuadra, G.R.6
-
26
-
-
80255122737
-
Fumarase: A paradigm of dual targeting and dual localized functions
-
21929734 10.1111/j.1742-4658.2011.08359.x 1:CAS:528:DC%2BC3MXhsFaksrnK
-
Yogev O, Naamati A, Pines O (2011) Fumarase: a paradigm of dual targeting and dual localized functions. FEBS J 278:4230-4242
-
(2011)
FEBS J
, vol.278
, pp. 4230-4242
-
-
Yogev, O.1
Naamati, A.2
Pines, O.3
|