Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase

Journal of Biological Chemistry

Volumn 286, Issue 24, 2011, Pages 21100-21109

  Mescam, Muriel ^a   Vinnakota, Kalyan C ^a   Beard, Daniel A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ATP SYNTHESIS; CATALYTIC MECHANISMS; COMPETITIVE BINDING; FIVE-STATE MODEL; FUMARATES; HYDRATION REACTION; INITIAL VELOCITIES; ISOTOPE EXCHANGE; KINETIC BEHAVIOR; KINETIC MODELS; MODEL PARAMETERS; PRIMARY REACTION; PROTONATED; REACTION CATALYZED; SUBSTRATE CONCENTRATIONS; TIME COURSE; TRICARBOXYLIC ACID CYCLE;

CATALYSIS; ENZYMES; HYDRATION; ISOTOPES; PROTONS; SYNTHESIS (CHEMICAL);

KINETICS;

BUFFER; FUMARATE HYDRATASE; MALIC ACID; PHOSPHATE;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME KINETICS; ENZYME SUBSTRATE; HYDRATION; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; REGULATORY MECHANISM;

ANIMALS; BIOCHEMISTRY; CATALYSIS; CATALYTIC DOMAIN; CITRIC ACID CYCLE; FUMARATE HYDRATASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART; KINETICS; MALATES; MODELS, CHEMICAL; MYOCARDIUM; SWINE; THERMODYNAMICS; TIME FACTORS;

EID: 79958729718     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.214452     Document Type: Article

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