An ENU mutagenesis screen in zebrafish for visual system mutants identifies a novel splice-acceptor site mutation in patched2 that results in colobomas

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 13, 2012, Pages 8214-8221

  Lee, Jiwoon ^a   Cox, Ben D ^a   Daly, Christina M S ^a   Lee, Chanjae ^a   Nuckels, Richard J ^a   Tittle, Rachel K ^a   Uribe, Rosa A ^a   Gross, Jeffrey M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPAMINE; ETHYLNITROSOUREA; PROTEIN PATCHED 2; SONIC HEDGEHOG PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLOBOMA; CONTROLLED STUDY; DNA SEQUENCE; EMBRYO; EYE DEVELOPMENT; EYE DISEASE; FEMALE; GENE MUTATION; GENETIC SCREENING; IN SITU HYBRIDIZATION; INTRON; MALE; MUTAGENESIS; MUTANT; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VISUAL SYSTEM; ZEBRA FISH;

ALKYLATING AGENTS; ALLELES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COLOBOMA; EMBRYO, NONMAMMALIAN; ETHYLNITROSOUREA; EYE; FEMALE; GENES, RECESSIVE; HEDGEHOG PROTEINS; IN SITU HYBRIDIZATION; LENS, CRYSTALLINE; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; POLYMERASE CHAIN REACTION; RETINA; RNA SPLICE SITES; SEQUENCE ANALYSIS, DNA; VERATRUM ALKALOIDS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84873386881     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-11061     Document Type: Article

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