Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 3, 2013, Pages

  Thamotharan, Shanthie ^a   Stout, David ^a   Shin, Bo Chul ^a   Devaskar, Sherin U ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene expression; Neurons; Ontogeny; Placenta; Synaptogenesis; Transcriptional control; Transgenic mouse

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CYCLINE; GLUCOSE TRANSPORTER 3; LUCIFERASE; MEMBRANE PROTEIN; MESSENGER RNA; NEURO D6 PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BRAIN; CELL DIVISION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENZYME ACTIVITY; EX VIVO STUDY; GENETIC TRANSCRIPTION; GESTATIONAL AGE; HYPOXIA; IN VIVO STUDY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; SKELETAL MUSCLE; SKIN; SYNAPTOGENESIS; TESTIS; TRANSGENE;

ANIMALS; BRAIN; FEMALE; GENES, REPORTER; GLUCOSE TRANSPORTER TYPE 3; LUCIFERASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; PLACENTA; PREGNANCY; TISSUE DISTRIBUTION; TRANSCRIPTIONAL ACTIVATION; TRANSGENES;

EID: 84873360377     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00214.2012     Document Type: Article

References (44)

1. Colville CA, Seatter MJ, Jess TJ, Gould GW, Thomas HM. Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors. Biochem J 290: 701-706, 1993.
2. Contag CH, Bachmann MH. Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng 4: 235-260, 2002.
3. Cross JC, Baczyk D, Dobric N, Hemberger M, Hughes M, Simmons DG, Yamamoto H, Kingdom JC. Genes, development and evolution of the placenta. Placenta 24: 123-130, 2003.
4. Das UG, Schroeder RE, Hay WW Jr, Devaskar SU. Time-dependent and tissue-specific effects of circulating glucose on fetal ovine glucose transporters. Am J Physiol Regul Integr Comp Physiol 276: R809-R817, 1999.
5. Devaskar SU, Devaskar UP, Schroeder RE, deMello D, Fiedorek FT Jr, Mueckler M. Expression of genes involved in placental glucose uptake and transport in the nonobese diabetic mouse pregnancy. Am J Obstet Gynecol 171: 1316-1323, 1994.
6. Devaskar SU, Rajakumar PA, Mink RB, McKnight RA, Thamotha-ran S, Hicks SJ. Effect of development and hypoxic-ischemia upon rabbit brain glucose transporter expression. Brain Res 823: 113-128, 1999.
7. Devaskar SU, Raychaudhuri S. Epigenetics-a science of heritable biological adaptation. Pediatr Res 61: 1R-4R, 2007.
8. Fields HM, Rinaman L, Devaskar SU. Distribution of glucose transporter isoform-3 and hexokinase I in the postnatal murine brain. Brain Res 846: 260-264, 1999.
9. Fung C, Evans E, Shin D, Shin BC, Zhao Y, Sankar R, Chaudhuri G, Devaskar SU. Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. J Neurosci Res 88: 3386-3398, 2010.
10. Ganguly A, McKnight RA, Raychaudhuri S, Shin BC, Ma Z, Moley K, Devaskar SU. Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction. Am J Physiol Endocrinol Metab 292: E1241-E1255, 2007.
11. Gerhart DZ, Leino RL, Borson ND, Taylor WE, Gronlund KM, McCall AL, Drewes LR. Localization of glucose transporter GLUT 3 in brain: comparison of rodent and dog using species-specific carboxyl-terminal antisera. Neuroscience 66: 237-246, 1995.
12. Hoffpauir BK, Grimes JL, Mathers PH, Spirou GA. Synaptogenesis of the calyx of Held: rapid onset of function and one-to-one morphological innervation. J Neurosci 26: 5511-5523, 2006.
13. Huang S, Czech MP. The GLUT4 glucose transporter. Cell Metab 5: 237-252, 2007.
14. Jansson T, Wennergren M, Illsley NP. Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation. J Clin Endocrinol Metab 77: 1554-1562, 1993.
15. Kamei Y, Tsutsumi O, Yamakawa A, Oka Y, Taketani Y, Imaki J. Maternal epidermal growth factor deficiency causes fetal hypoglycemia and intrauterine growth retardation in mice: possible involvement of placental glucose transporter GLUT3 expression. Endocrinology 140: 4236-4243, 1999.
16. Kayano T, Fukumoto H, Eddy RL, Fan YS, Byers MG, Shows TB, Bell GI. Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J Biol Chem 263: 15245-15248, 1988.
17. Khan JY, Rajakumar RA, McKnight RA, Devaskar UP, Devaskar SU. Developmental regulation of genes mediating murine brain glucose uptake. Am J Physiol Regul Integr Comp Physiol 276: R892-R900, 1999.
18. Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA. Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. Mol Ther 14: 779-788, 2006.
19. Lipshutz GS, Gruber CA, Cao Y, Hardy J, Contag CH, Gaensler KM. In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression. Mol Ther 3: 284-292, 2001.
20. Maher F, Simpson IA. Modulation of expression of glucose transporters GLUT3 and GLUT1 by potassium and N-methyl-D-aspartate in cultured cerebellar granule neurons. Mol Cell Neurosci 5: 369-375, 1994.
21. Mantych GJ, James DE, Chung HD, Devaskar SU. Cellular localization and characterization of Glut 3 glucose transporter isoform in human brain. Endocrinology 131: 1270-1278, 1992.
22. Maratou E, Dimitriadis G, Kollias A, Boutati E, Lambadiari V, Mitrou P, Raptis SA. Glucose transporter expression on the plasma membrane of resting and activated white blood cells. Eur J Clin Invest 37: 282-290, 2007.
23. Matsumoto K, Akazawa S, Ishibashi M, Trocino RA, Matsuo H, Yamasaki H, Yamaguchi Y, Nagamatsu S, Nagataki S. Abundant expression of GLUT1 and GLUT3 in rat embryo during the early organo-genesis period. Biochem Biophys Res Commun 209: 95-102, 1995.
24. Nagamatsu S, Kornhauser JM, Burant CF, Seino S, Mayo KE, Bell GI. Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization. J Biol Chem 267: 467-472, 1992.
25. Nagamatsu S, Sawa H, Nakamichi Y, Katahira H, Inoue N. Developmental expression of GLUT3 glucose transporter in the rat brain. FEBS Lett 346: 161-164, 1994.
26. Pessin JE, Bell GI. Mammalian facilitative glucose transporter family: structure and molecular regulation. Annu Rev Physiol 54: 911-930, 1992.
27. Rajakumar A, Thamotharan S, Raychaudhuri N, Menon RK, Devaskar SU. Trans-activators regulating neuronal glucose transporter isoform-3 gene expression in mammalian neurons. J Biol Chem 279: 26768-26779, 2004.
28. Rajakumar RA, Thamotharan S, Menon RK, Devaskar SU. Sp1 and Sp3 regulate transcriptional activity of the facilitative glucose transporter isoform-3 gene in mammalian neuroblasts and trophoblasts. J Biol Chem 273: 27474-27483, 1998.
29. Sankar R, Thamotharan S, Shin D, Moley KH, Devaskar SU. Insulin-responsive glucose transporters-GLUT8 and GLUT4 are expressed in the developing mammalian brain. Brain Res Mol Brain Res 107: 157-165, 2002.
30. Sato M, Nakamura Y, Sogawa T, Yang Q, Taniguchi T, Taniguchi E, Kagiya T, Nakamura M, Mori I, Kakudo K. Immunolocalization of glucose transporter 1 and 3 in the placenta: application to cytodiagnosis of Papanicolaou smear. Diagn Cytopathol 26: 373-379, 2002.
31. Shin BC, Fujikura K, Suzuki T, Tanaka S, Takata K. Glucose transporter GLUT3 in the rat placental barrier: a possible machinery for the transplacental transfer of glucose. Endocrinology 138: 3997-4004, 1997.
32. Singh BS, Westfall TC, Devaskar SU. Maternal diabetes-induced hyper-glycemia and acute intracerebral hyperinsulinism suppress fetal brain neuropeptide Y concentrations. Endocrinology 138: 963-969, 1997.
33. Szentirmai O, Baker CH, Lin N, Szucs S, Takahashi M, Kiryu S, Kung AL, Mulligan RC, Carter BS. Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect. Neurosurgery 58: 365-372; discussion 365-372, 2006.
34. Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R. In vivo tracking of neural progenitor cell migration to glioblastomas. Hum Gene Ther 14: 1247-1254, 2003.
35. Thamotharan M, Shin BC, Suddirikku DT, Thamotharan S, Garg M, Devaskar SU. GLUT4 expression and subcellular localization in the intrauterine growth-restricted adult rat female offspring. Am J Physiol Endocrinol Metab 288: E935-E947, 2005.
36. Thorens B, Mueckler M. Glucose transporters in the 21st Century. Am J Physiol Endocrinol Metab 298: E141-E145, 2010.
37. Urabe T, Hattori N, Nagamatsu S, Sawa H, Mizuno Y. Expression of glucose transporters in rat brain following transient focal ischemic injury. J Neurochem 67: 265-271, 1996.
38. Vannucci SJ. Developmental expression of GLUT1 and GLUT3 glucose transporters in rat brain. J Neurochem 62: 240-246, 1994.
39. Vannucci SJ, Seaman LB, Brucklacher RM, Vannucci RC. Glucose transport in developing rat brain: glucose transporter proteins, rate constants and cerebral glucose utilization. Mol Cell Biochem 140: 177-184, 1994.
40. Vannucci SJ, Willing LB, Vannucci RC. Developmental expression of glucose transporters, GLUT1 and GLUT3, in postnatal rat brain. Adv Exp Med Biol 331: 3-7, 1993.
41. Yamaguchi M, Sakata M, Ogura K, Miyake A. Gestational changes of glucose transporter gene expression in the mouse placenta and decidua. J Endocrinol Invest 19: 567-569, 1996.
42. Zhao FQ, Keating AF. Functional properties and genomics of glucose transporters. Curr Genomics 8: 113-128, 2007.
43. Zhao Y, Fung C, Shin D, Shin BC, Thamotharan S, Sankar R, Ehninger D, Silva A, Devaskar SU. Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. Mol Psychiatry 15: 286-299, 2010.
44. Zovein A, Flowers-Ziegler J, Thamotharan S, Shin D, Sankar R, Nguyen K, Gambhir S, Devaskar SU. Postnatal hypoxic-ischemic brain injury alters mechanisms mediating neuronal glucose transport. Am J Physiol Regul Integr Comp Physiol 286: R273-R282, 2004.