Platelet-rich fibrin matrix in the management of arthroscopic repair of the rotator cuff: A prospective, randomized, double-blinded study

American Journal of Sports Medicine

Volumn 41, Issue 2, 2013, Pages 263-270

  Weber, Stephen C ^a   Kauffman, Jeffrey I ^b   Parise, Carol ^c   Weber, Sophia J ^a   Katz, Stephen D ^d  

^a Sacramento Knee and Sports Medicine   (United States)

^b Orthopedic Associates of Dutchess County   (United States)

^c Sutter Institute for Medical Research   (United States)

^d Freeport Maine ^*  (United States)

Author keywords

biological augmentation; growth factor; platelet; rotator cuff repair

Indexed keywords

FIBRIN;

AGED; ARTHROSCOPY; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; INJURY; MALE; MIDDLE AGED; PHYSIOLOGY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; ROTATOR CUFF; TENDON INJURY; THROMBOCYTE RICH PLASMA; WOUND HEALING;

AGED; ARTHROSCOPY; DOUBLE-BLIND METHOD; FEMALE; FIBRIN; HUMANS; MALE; MIDDLE AGED; PLATELET-RICH PLASMA; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; ROTATOR CUFF; TENDON INJURIES; WOUND HEALING;

MLCS; MLOWN;

EID: 84873351003     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546512467621     Document Type: Article

References (45)

1. Anderson LJ, Anziano D. Use of platelet rich fibrin matrix in rotator cuff repairs. J Arthrosc. 2009 ; 5 (12). 1363
2. Angel MJ, Sgaglione NA, Grande DA. Clinical applications of bioactive factors in sports medicine: current concepts and future trends. Sports Med Arthrosc. 2006 ; 14 (3). 138-145
3. Arnoczky SP, Anderson LJ, Fanelli GC, et al. The role of platelet-rich plasma in connective tissue repair. Orthop Today. 2009 ; 29 (3). 26-31
4. Barber FA, Hrnack SA, Snyder SJ, Hapa O. Rotator cuff repair healing influenced by platelet-rich plasma construct augmentation. Arthroscopy. 2011 ; 27 (8). 1029-1035
5. Bergeson AG, Tashjian RZ, Greis PE, et al. Effects of platelet-rich fibrin matrix on repair integrity of at-risk rotator cuff tears. Am J Sports Med. 2012 ; 40 (2). 286-293
6. Bhandari M, Busse JW, Jackowski D, et al. Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. CMAJ. 2004 ; 170 (4). 477-480
7. Bishop J, Klepps S, Lo IK, et al. Cuff integrity after arthroscopic versus open rotator cuff repair: a prospective study. J Shoulder Elbow Surg. 2006 ; 15 (3). 290-299
8. BoyanBDSchwartzZPattersonTE. Clinical use of platelet-rich plasma in orthopaedics. Available at: http://www.aaos.org/news/bulletin/sep07/research2. asp. Accessed 2009.
9. Buford DA. Rotator cuff healing with and without platelet rich plasma application. Arthroscopy. 2011 ; 27 (5). e37 - e38
10. CascadeAPS. Available at: http://www.platelettherapy.com. Accessed 2009.
11. Castillo TN, Pouliot MA, Kim HJ, Dragoo JL. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med. 2011 ; 39 (2). 266-271
12. Castricini R, Longo UG, De Benedetto M, et al. Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial. Am J Sports Med. 2011 ; 39 (2). 258-265
13. Dines JS, Grande DA, Dines DM. Tissue engineering and rotator cuff tendon healing. J Shoulder Elbow Surg. 2007 ; 16: S204 - S207
14. Dines JS, Weber L, Razzano P, et al. The effect of growth differentiation factor-5-coated sutures on tendon repair in a rat model. J Shoulder Elbow Surg. 2007 ; 16: S215 - S221
15. Everts PA, Devilee RJ, Brown Mahoney C, et al. Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome: a prospective randomized double-blind study. Eur Surg Res. 2008 ; 40 (2). 203-210
16. Everts PA, Knape JT, Weibrich G, et al. Platelet-rich plasma and platelet gel: a review. J Extra Corpor Technol. 2006 ; 38 (2). 174-187
17. Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med. 2009 ; 37 (11). 2259-2272
18. Galatz LM, Ball CM, Teefey SA, Middleton WD, Yamagushi K. The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears. J Bone Joint Surg Am. 2004 ; 86 (2). 219-224
19. Gamradt SC, Rodeo SA, Warren RF. Platelet rich plasma in rotator cuff repair. Tech Orthop. 2007 ; 22 (1). 26-33
20. Gulotta LV, Rodeo SA. Growth factors for rotator cuff repair. Clin Sports Med. 2009 ; 28 (1). 13-23
21. HallMP. "Bloody" treatment holds promise. Available at: http://www.aaos.org/news/aaosnow/nov09/cover3.asp. Accessed 2009.
22. Hall MP, Band PA, Meislin RJ, Jazrawi LM, Cardone DA. Platelet-rich plasma: current concepts and application in sports medicine. J Am Acad Orthop Surg. 2009 ; 17 (10). 602-608
23. Han B, Woodell-May J, Ponticiello M, Yang Z, Nimni M. The effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity. J Bone Joint Surg Am. 2009 ; 91 (6). 1459-1470
24. Harris NL, Huffer WE, von Stade E, et al. The effect of platelet rich plasma (PRP) on normal soft tissues in the rabbit. J Bone Joint Surg Am. 2012 ; 94 (9). 786-793
25. HasanSNayyarSKalraK. The effect of platelet-rich fibrin matrix on rotator cuff healing in rat model. Paper presented at: American Academy of Orthopedic Surgeons Annual Meeting; February 7-11, 2012; San Francisco, California. Available at: www.aaos.org/Education/anmeet/education/Sports-Medicine- Arthoroscopy-Abstracts.pdf. Accessed October 19, 2012.
26. Jo CH, Kim JE, Yoon KS, et al. Does platelet-rich plasma accelerate recovery after rotator cuff repair? A prospective cohort study. Am J Sports Med. 2011 ; 39 (10). 2082-2090
27. Lou J, Tu Y, Burns M, Silva MJ, Manske P. BMP-12 gene transfer augmentation of lacerated tendon repair. J Orthop Res. 2001 ; 19 (6). 1199-1202
28. Maniscalco P, Gambera D, Lunati A, et al. The "Cascade" membrane: a new PRP device for tendon ruptures. Description and case report on rotator cuff tendon. Acta Biomed. 2008 ; 79 (3). 223-226
29. McAuleyDF. Opioid/narcotic analgesic converter. Available at: http://Globalrph.com/narcoticomv/htm. Accessed November 30, 2009.
30. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006 ; 34 (11). 1774-1778
31. Mishra A, Woodall J, Vieira A. Treatment of tendon and muscle using platelet-rich plasma. Clin Sports Med. 2009 ; 28 (1). 113-125
32. Murachovsky J, Ikemoto RY, Nascimento LG, et al. Evaluation of the rotator cuff repair in sheep: does the platelet rich plasma therapy help?. Arthroscopy. 2011 ; 27 (10). e249
33. Murray DH, Kubiak EN, Jazrawi LM, et al. The effect of cartilage-derived morphogenetic protein 2 on initial healing of a rotator cuff defect in a rat model. J Shoulder Elbow Surg. 2007 ; 16 (2). 251-254
34. Okike K, Kocher MS, Wei EX, Mehlman CT, Bhandari M. Accuracy of conflict-of-interest disclosures reported by physicians. N Engl J Med. 2009 ; 361 (15). 1466-1474
35. Orrego M, Larrain C, Rosales J, et al. Effects of platelet concentrate and a bone plug on the healing of hamstring tendons in a bone tunnel. Arthroscopy. 2008 ; 24 (12). 1373-1380
36. Paoloni JA, Appleyard RC, Nelson J, Murrell GA. Topical glyceryl trinitrate application in the treatment of chronic supraspinatus tendinopathy: a randomized, double-blinded, placebo-controlled clinical trial. Am J Sports Med. 2005 ; 33 (6). 806-813
37. Randelli PS, Arrigoni P, Cabitza P, Volpi P, Maffulli N. Autologous platelet rich plasma for arthroscopic rotator cuff repair: a pilot study. Disabil Rehabil. 2008 ; 30 (20-22). 1584-1589
38. Randelli P, Arrigoni P, Ragone V, Aliprandi A, Cabitza P. Autologous platelet rich plasma in arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up. J Shoulder Elbow Surg. 2011 ; 20 (4). 518-528
39. Rodeo SA, Delos D, Williams RJ, et al. The effect of platelet-rich fibrin matrix on rotator cuff tendon healing: a prospective, randomized clinical study. Am J Sports Med. 2012 ; 40 (6). 1234-1241
40. Schepull T, Aspenberg P, Berlin G, Trinks M. Platelet concentrate does not improve the mechanical properties of a ruptured Achilles tendon. J Bone Joint Surg Br. 2010 ; 92: 590
41. SchwartzA. A promising treatment for athletes, in blood. NY Times. February16, 2009. Available at: http://www.nytimes.com/2009/02/17/sports/ 17blood.html?pagewanted=all&-r=0. Accessed 2009.
42. Seeherman HJ, Archambault JM, Rodeo SA, et al. rhBMP-12 accelerates healing of rotator cuff repairs in a sheep model. J Bone Joint Surg Am. 2008 ; 90 (10). 2206-2219
43. Sugaya H, Maeda K, Matsuki K, Moriishi J. Functional and structural outcome after arthroscopic full-thickness rotator cuff repair: single-row versus dual-row fixation. Arthroscopy. 2005 ; 21 (11). 1307-1316
44. Thomopoulos S, Soslowsky LJ, Flanagan CL, et al. The effect of fibrin clot on healing rat supraspinatus tendon defects. J Shoulder Elbow Surg. 2002 ; 11 (3). 239-247
45. Zumstein MA, Rumian A, O'Seha K, et al. Use of platelet- and leukocyte-rich fibrin (L-PRF) improves early vascularization but does not affect late rotator cuff tendon healing. J Shoulder Elbow Surg. :