Synthesis of novel and complex tetrahydroquinazolinedione and Dihydropyrido[2,3- d ]pyrimidine derivatives via a one-pot [4+2]-cycloadddition strategy

Synlett

Volumn 24, Issue 4, 2013, Pages 471-474

  Sarmah, Manas M ^a   Prajapati, Dipak ^a   Hu, Wenhao ^b  

^a CSIR NORTH EAST INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^b EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

dihydropyrido 2,3 d pyrimidines; phase transfer conditions; tetrahydroquinazolinediones; zwitterionic species

Indexed keywords

DIHYDROPYRIDO[2,3 D]PYRIMIDINE DERIVATIVE; HETEROCYCLIC COMPOUND; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TETRAHYDROQUINAZOLINEDIONE DERIVATIVE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPLEX FORMATION; CYCLOADDITION; DRUG DETERMINATION; DRUG SYNTHESIS; MASS SPECTROMETRY; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM YIELD;

EID: 84873343271     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0032-1317792     Document Type: Article

References (17)

1. Orain, D.; Ofner, S.; Koller, M.; Carache, D. A.; Froestl, W.; Allgeier, H.; Rasetti, V.; Nozulak, J.; Mattes, H.; Soldermann, N.; Floersheim, P.; Desrayaud, S.; Kallen, J.; Lingenhoehl, K.; Urwyler, S. Bioorg. Med. Chem. Lett. 2012, 22, 996.
2. Pan, L.; Tan, J.-H.; Hou, J.-Q.; Huang, S.- L.; Gu, L.-Q.; Huang, J.-H. Bioorg. Med. Chem. Lett. 2008, 18, 3790.
3. Willis, M. C.; Snell, R. H.; Fletcher, A. J.; Woodward, R. L. Org. Lett. 2006, 8, 5089.
4. Li, Z.; Huang, H.; Sun, H.; Jiang, H.; Liu, H. J. Comb. Chem. 2008, 10, 484.
5. Choo, H.-Y. P.; Kim, M.; Lee, S. K.; Kim, S. W.; Chung, I. K. Bioorg. Med. Chem. 2002, 10, 517.
6. Wagner, G.; Wunderlich, I. Pharmazie 1978, 33, 15.
7. Ibrahim, S. S.; Abdel-Halim, A. M.; Gabr, Y.; El-Edfawy, S.; Abdel- Rahman, R. J. Chem. Res., Synop. 1997, 154.
8. Hori, M.; Iemura, R.; Hara, H.; Ozaki, A.; Sukamoto, T.; Ohtaka, H. Chem. Pharm. Bull. 1990, 38, 1286.
9. LeMahieu, R. A.; Carson, M.; Nason, W. C.; Parrish, D. R.; Welton, A. F.; Baruth, H. W.; Yaremko, B. J. Med. Chem. 1983, 26, 420.
10. Walsh, E. B.; Wamhoff, H. Chem. Ber. 1989, 122, 1673.
11. Hirota, K.; Kuki, H.; Maki, Y. Heterocycles 1994, 37, 563.
12. Tkachenko, Y. N.; Tsupak, E. B.; Pozharskii, A. F. Chem. Heterocycl. Compd. 2000, 36, 307.
13. Sarma, R.; Sarmah, M. M.; Prajapati, D. J. Org. Chem. 2012, 77, 2018.
14. Sarma, R.; Prajapati, D. Synlett 2008, 301.
15. Prajapati, D.; Gohain, M.; Thakur, A. J. Bioorg. Med. Chem. Lett. 2006, 16, 3537.
16. Prajapati, D.; Thakur, A. J. Tetrahedron Lett. 2005, 46, 1433.
17. Gairaced, C. B.; Lappin, G. R. J. Org. Chem. 1953, 18, 1.