Retinoic acid rescues alveolar hypoplasia in the calorie-restricted developing rat lung

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 2, 2013, Pages 179-187

  Londhe, Vedang A ^a   Maisonet, Tiffany M ^a   Lopez, Benjamin ^a   Shin, Bo Chul ^a   Huynh, Jasmine ^a   Devaskar, Sherin U ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bronchopulmonary dysplasia; Intrauterine growth retardation; RARa; TGF ; Vitamin A

Indexed keywords

ELASTIN; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; INTRAUTERINE GROWTH RETARDATION; LUNG DEVELOPMENT; LUNG HYPOPLASIA; NONHUMAN; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REFEEDING; SIGNAL TRANSDUCTION;

ANIMALS; CALORIC RESTRICTION; ELASTIN; FEMALE; HYPERPLASIA; LUNG; MATERNAL EXPOSURE; PREGNANCY; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, RETINOIC ACID; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRETINOIN;

EID: 84873339994     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0229OC     Document Type: Article

References (46)

1. Barker DJ, Eriksson JG, Forsen T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol 2002; 31:1235-1239.
2. Rosenberg A. The IUGR newborn. Semin Perinatol 2008;32:219-224.
3. McIntire DD, Bloom SL, Casey BM, Leveno KJ. Birth weight in relation to morbidity and mortality among newborn infants. N Engl J Med 1999;340:1234-1238.
4. Kotecha SJ, Watkins WJ, Heron J, Henderson J, Dunstan FD, Kotecha S. Spirometric lung function in school-age children: effect of intrauterine growth retardation and catch-up growth. Am J Respir Crit Care Med 2010;181:969-974.
5. Maden M, Hind M. Retinoic acid in alveolar development, maintenance and regeneration. Philos Trans R Soc Lond B Biol Sci 2004;359:799-808.
6. Dirami G, Massaro GD, Clerch LB, Ryan US, Reczek PR, Massaro D. Lung retinol storing cells synthesize and secrete retinoic acid, an inducer of alveolus formation. Am J Physiol Lung Cell Mol Physiol 2004;286:L249-L256.
7. Massaro GD, Massaro D. Retinoic acid treatment partially rescues failed septation in rats and in mice. Am J Physiol Lung Cell Mol Physiol 2000;278:L955-L960.
8. Whitney D, Massaro GD, Massaro D, Clerch LB. Gene expression of cellular retinoid-binding proteins: modulation by retinoic acid and dexamethasone in postnatal rat lung. Pediatr Res 1999;45:2-7.
9. Hind M, Maden M. Retinoic acid induces alveolar regeneration in the adult mouse lung. Eur Respir J 2004;23:20-27.
10. Tyson JE, Wright LL, Oh W, Kennedy KA, Mele L, Ehrenkranz RA, Stoll BJ, Lemons JA, Stevenson DK, Bauer CR, et al. Vitamin A supplementation for extremely-low-birth-weight infants: National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 1999;340:1962-1968.
11. Garg M, Thamotharan M, Pan G, Lee PW, Devaskar SU. Early exposure of the pregestational intrauterine and postnatal growth-restricted female offspring to a peroxisome proliferator-activated receptor-{gamma} agonist. Am J Physiol Endocrinol Metab 2010;298:E489-E498.
12. Raychaudhuri N, Raychaudhuri S, Thamotharan M, Devaskar SU. Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring. J Biol Chem 2008;283: 13611-13626.
13. Massaro GD, Massaro D. Formation of pulmonary alveoli and gasexchange surface area: quantitation and regulation. Annu Rev Physiol 1996;58:73-92.
14. Londhe VA, Belperio JA, Keane MP, Burdick MD, Xue YY, Strieter RM. CXCR2/CXCR2 ligand biological axis impairs alveologenesis during dsRNA-induced lung inflammation in mice. Pediatr Res 2005; 58:919-926.
15. Londhe VA, Nguyen HT, Jeng JM, Li X, Li C, Tiozzo C, Zhu N, Minoo P. NF-kB induces lung maturation during mouse lung morphogenesis. Dev Dyn 2008;237:328-338.
16. Londhe VA, Maisonet TM, Lopez B, Jeng JM, Xiao J, Li C, Minoo P. Conditional deletion of epithelial IKKbeta impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis. Respir Res 2011;12:134.
17. Londhe VA, Maisonet TM, Lopez B, Jeng JM, Li C, Minoo P. A subset of epithelial cells with CCSP promoter activity participates in alveolar development. Am J Respir Cell Mol Biol 2011;44:804-812.
18. Burri PH, Dbaly J, Weibel ER. The postnatal growth of the rat lung: I. Morphometry. Anat Rec 1974;178:711-730.
19. Cooney TP, Thurlbeck WM. The radial alveolar count method of Emery and Mithal: a reappraisal 2-intrauterine and early postnatal lung growth. Thorax 1982;37:580-583.
20. Cooney TP, Thurlbeck WM. The radial alveolar count method of Emery and Mithal: a reappraisal 1-postnatal lung growth. Thorax 1982;37: 572-579.
21. O'Brien EA, Barnes V, Zhao L, McKnight RA, Yu X, Callaway CW, Wang L, Sun JC, Dahl MJ, Wint A, et al. Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. Am J Physiol Regul Integr Comp Physiol 2007;293:R314-R322.
22. Maritz GS, Cock ML, Louey S, Suzuki K, Harding R. Fetal growth restriction has long-term effects on postnatal lung structure in sheep. Pediatr Res 2004;55:287-295.
23. Gruppuso PA, Boylan JM, Anand P, Bienieki TC. Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. Pediatr Res 2005;57:185-191.
24. Equils O, Singh S, Karaburun S, Lu D, Thamotharan M, Devaskar SU. Intra-uterine growth restriction downregulates the hepatic Toll like receptor-4 expression and function. Clin Dev Immunol 2005;12:59-66.
25. Yin R, Tian F, Frankenberger B, de Angelis MH, Stoeger T. Selection and evaluation of stable housekeeping genes for gene expression normalization in carbon nanoparticle-induced acute pulmonary inflammation in mice. Biochem Biophys Res Commun 2010;399:531-536.
26. Massaro GD, Massaro D. Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats. Am J Physiol 1996;270: L305-L310.
27. Joss-Moore LA, Wang Y, Yu X, Campbell MS, Callaway CW, McKnight RA, Wint A, Dahl MJ, Dull RO, Albertine KH, et al. IUGR decreases elastin mRNA expression in the developing rat lung and alters elastin content and lung compliance in the mature rat lung. Physiol Genomics 2011;43:499-505.
28. Shi W, Chen F, Cardoso WV. Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6:558-563.
29. Burri PH. The postnatal growth of the rat lung: 3. Morphology. Anat Rec 1974;180:77-98.
30. Checkley W, West KP Jr, Wise RA, Baldwin MR, Wu L, LeClerq SC, Christian P, Katz J, Tielsch JM, Khatry S, et al. Maternal vitamin A supplementation and lung function in offspring. N Engl J Med 2010; 362:1784-1794.
31. Lipsett J, Tamblyn M, Madigan K, Roberts P, Cool JC, Runciman SI, McMillen IC, Robinson J, Owens JA. Restricted fetal growth and lung development: a morphometric analysis of pulmonary structure. Pediatr Pulmonol 2006;41:1138-1145.
32. Massaro D, Alexander E, Reiland K, Hoffman EP, Massaro GD, Clerch LB. Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction. Am J Physiol Lung Cell Mol Physiol 2007;292:L1313-L1326.
33. Sahebjami H, MacGee J. Effects of starvation on lung mechanics and biochemistry in young and old rats. J Appl Physiol 1985;58:778-784.
34. Sahebjami H, Domino M. Effects of repeated cycles of starvation and refeeding on lungs of growing rats. J Appl Physiol 1992;73:2349-2354.
35. Das RM. The effects of intermittent starvation on lung development in suckling rats. Am J Pathol 1984;117:326-332.
36. Rehan VK, Sakurai R, Li Y, Karadag A, Corral J, Bellusci S, Xue YY, Belperio J, Torday JS. Effects of maternal food restriction on offspring lung extracellular matrix deposition and long term pulmonary function in an experimental rat model. Pediatr Pulmonol 2012;47:162-171.
37. Hind M, Corcoran J, Maden M. Temporal/spatial expression of retinoid binding proteins and RAR isoforms in the postnatal lung. Am J Physiol Lung Cell Mol Physiol 2002;282:L468-L476.
38. Massaro GD, Massaro D, Chan WY, Clerch LB, Ghyselinck N, Chambon P, Chandraratna RA. Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiol Genomics 2000; 4:51-57.
39. McGowan S, Jackson SK, Jenkins-Moore M, Dai HH, Chambon P, Snyder JM. Mice bearing deletions of retinoic acid receptors demonstrate reduced lung elastin and alveolar numbers. Am J Respir Cell Mol Biol 2000;23:162-167.
40. McGowan SE, Doro MM, Jackson SK. Endogenous retinoids increase perinatal elastin gene expression in rat lung fibroblasts and fetal explants. Am J Physiol 1997;273:L410-L416.
41. Okabe T, Yorifuji H, Yamada E, Takaku F. Isolation and characterization of vitamin-A-storing lung cells. Exp Cell Res 1984;154:125-135.
42. Chen F, Desai TJ, Qian J, Niederreither K, Lu J, Cardoso WV. Inhibition of TGF beta signaling by endogenous retinoic acid is essential for primary lung bud induction. Development 2007;134:2969-2979.
43. Albertine KH, Dahl MJ, Gonzales LW, Wang ZM, Metcalfe D, Hyde DM, Plopper CG, Starcher BC, Carlton DP, Bland RD. Chronic lung disease in preterm lambs: effect of daily vitamin A treatment on alveolarization. Am J Physiol Lung Cell Mol Physiol 2010;299:L59-L72.
44. Galambos C, Demello DE. Regulation of alveologenesis: clinical implications of impaired growth. Pathology 2008;40:124-140.
45. Devaskar SU, deMello DE. Cell-specific localization of glucose transporter proteins in mammalian lung. J Clin Endocrinol Metab 1996;81:4373-4378.
46. Shin BC, Dai Y, Thamotharan M, Gibson LC, Devaskar SU. Pre- and postnatal calorie restriction perturbs early hypothalamic neuropeptide and energy balance. J Neurosci Res 2012;90:1169-1182.