Surgical angiogenesis with short-term immunosuppression maintains bone viability in rabbit allogenic knee joint transplantation

Plastic and Reconstructive Surgery

Volumn 131, Issue 2, 2013, Pages

  Kremer, Thomas ^a,b,c   Giessler, Goetz A ^a,b,c   Friedrich, Patricia F ^a,b,c   Willems, Wouter F ^a,b,c   Giusti, Guilherme ^a,b,c   Bishop, Allen T ^a,b,c  

^a MAYO CLINIC   (United States)

^b BG Trauma Center Ludwigshafen   (Germany)

^c BG UNFALLKLINIK MURNAU   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; BLOOD VESSEL; BONE TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; KNEE; MALE; RABBIT; TIME; TISSUE SURVIVAL; TRANSPLANTATION; VASCULARIZATION;

ANIMALS; BLOOD VESSELS; BONE TRANSPLANTATION; IMMUNOSUPPRESSION; KNEE JOINT; MALE; RABBITS; TIME FACTORS; TISSUE SURVIVAL;

MLCS; MLOWN;

EID: 84873296078     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e3182789ad4     Document Type: Article

References (32)

1. Giessler GA, Zobitz M, Friedrich PF, Bishop AT. Host-derived neoangiogenesis with short-term immunosuppression allows incorporation and remodeling of vascularized diaphyseal allogeneic rabbit femur transplants. J Orthop Res. 2009;27: 763-770.
2. Ohno T, Pelzer M, Larsen M, Friedrich PF, Bishop AT. Hostderived angiogenesis maintains bone blood flow after withdrawal of immunosuppression. Microsurgery 2007;27:657-663. (Pubitemid 350175152)
3. Zaleske DJ, Ehrlich MG, Piliero C, May JW Jr, Mankin HJ. Growth-plate behavior in whole joint replantation in the rabbit. J Bone Joint Surg Am. 1982;64:249-258. (Pubitemid 12132618)
4. Siliski JM, Simpkin S, Green CJ. Vascularized whole knee joint allografts in rabbits immunosuppressed with cyclosporin A. Arch Orthop Trauma Surg. 1984;103:26-35. (Pubitemid 14145853)
5. Yaremchuk MJ, Sedacca T, Schiller AL, May JW Jr. Vascular knee allograft transplantation in a rabbit model. Plast Reconstr Surg. 1983;71:461-472. (Pubitemid 13111207)
6. Kremer T, Giusti G, Friedrich PF, Willems W, Bishop AT, Giessler GA. Knee joint transplantation combined with surgical angiogenesis in rabbits: A new experimental model. Microsurgery 2012;32:118-127.
7. Giessler GA, Friedrich PF, Shin RH, Bishop AT. The superficial inferior epigastric artery fascia flap in the rabbit. Microsurgery 2007;27:560-564. (Pubitemid 47519462)
8. Giessler GA, Zobitz M, Friedrich PF, Bishop AT. Transplantation of a vascularized rabbit femoral diaphyseal segment: Mechanical and histologic properties of a new living bone transplantation model. Microsurgery 2008;28:291-299. (Pubitemid 351770174)
9. Pelzer M, Larsen M, Chung YG, et al. Short-term immunosuppression and surgical neoangiogenesis with host vessels maintains long-term viability of vascularized bone allografts. J Orthop Res. 2007;25:370-377. (Pubitemid 46463643)
10. Shigetomi M, Hickey MJ, Hurley JV, Riccio M, Niazi ZB, Ohta I. Orthotopic vascularized osteochondral allografts in an immunosuppressed rat model. J Reconstr Microsurg. 1996;12: 113-119. (Pubitemid 26089287)
11. Doi K, Akino T, Shigetomi M, Muramatsu K, Kawai S. Vascularized bone allografts: Review of current concepts. Microsurgery 1994;15:831-841.
12. Siemionow MZ, Zor F, Gordon CR. Face, upper extremity, and concomitant transplantation: Potential concerns and challenges ahead. Plast Reconstr Surg. 2010;126:308-315.
13. Diefenbeck M, Wagner F, Kirschner MH, Nerlich A, Mückley T, Hofmann GO. Outcome of allogeneic vascularized knee transplants. Transpl Int. 2007;20:410-418. (Pubitemid 46535980)
14. Nakagawa T, Sukhova GK, Rabkin E, Winters GL, Schoen FJ, Libby P. Acute rejection accelerates graft coronary disease in transplanted rabbit hearts. Circulation 1995;92:987-993.
15. Larsen M, Pelzer M, Friedrich PF, Wood CM, Bishop AT. Living bone allotransplants survive by surgical angiogenesis alone: Development of a novel method of composite tissue allotransplantation. J Bone Joint Surg Am. 2011;93: 261-273.
16. Larsen M, Willems WF, Pelzer M, Friedrich PF, Yaszemski MJ, Bishop AT. Augmentation of surgical angiogenesis in vascularized bone allotransplants with host-derived a/v bundle implantation, fibroblast growth factor-2, and vascular endothelial growth factor administration. J Orthop Res. 2011;28: 1015-1021.
17. Willems WF, Kremer T, Friedrich P, Bishop AT. Surgical revascularization induces angiogenesis in orthotopic bone allograft. Clin Orthop Relat Res. 2012;470:2496-2502.
18. Larsen M, Pelzer M, Friedrich PF, Bishop AT. Measurement of bone blood flow using the hydrogen washout technique: Part II. Validation by comparison to microsphere entrapment. J Orthop Res. 2008;26:746-752.
19. Pelzer M, Larsen M, Friedrich PF, Bishop AT. Measurement of bone blood flow using the hydrogen washout technique: Part I. Quantitative evaluation of tissue perfusion in the laboratory rat. J Orthop Res. 2008;26:741-745.
20. Doi K, DeSantis G, Singer DI, et al. The effect of immunosuppression on vascularised allografts: A preliminary report. J Bone Joint Surg Br. 1989;71:576-582. (Pubitemid 19211210)
21. Hickey MJ, Ohta I, Shigetomi M, Hurley JV, Kuwata N, O'Brien BM. Vascularized heterotopic osteochondral allografts in a rat model following long-term immunosuppression. J Reconstr Microsurg. 1994;10:255-260. (Pubitemid 24239605)
22. Paskert JP, Yaremchuk MJ, Randolph MA, Weiland AJ. The role of cyclosporin in prolonging survival in vascularized bone allografts. Plast Reconstr Surg. 1987;80:240-247. (Pubitemid 17152457)
23. Vogelin E, Jones NF, Rao UN. Long-term viability of articular cartilage after microsurgical whole-joint transplantation and immunosuppression with rapamycin, mycophenolate mofetil, and tacrolimus. J Hand Surg Am. 2002;27: 307-315. (Pubitemid 34241195)
24. Muramatsu K, Doi K, Akino T, Shigetomi M, Kawai S. Results of vascularized joint allograft under immunosuppression with cyclosporine. Microsurgery 1993;14:527-536. (Pubitemid 23339369)
25. Muramatsu K, Kuriyama R, Taguchi T. Intragraft chimerism following composite tissue allotransplantation. J Surg Res. 2009;157:129-135
26. Pelzer M, Larsen M, Friedrich PF, Aleff RA, Bishop AT. Repopulation of vascularized bone allotransplants with recipient-derived cells: Detection by laser capture microdissection and real-time PCR. J Orthop Res. 2009;27:1514-1520.
27. Muramatsu K, Bishop AT. Cell repopulation in vascularized bone grafts. J Orthop Res. 2002;20:772-778. (Pubitemid 34822997)
28. Muramatsu K, Kurokawa Y, Kuriyama R, Taguchi T, Bishop AT. Gradual graft-cell repopulation with recipient cells following vascularized bone and limb allotransplantation. Microsurgery 2005;25:599-605. (Pubitemid 41759796)
29. Goldberg VM, Porter BB, Lance EM. Transplantation of the canine knee joint on a vascular pedicle: A preliminary study. J Bone Joint Surg Am. 1980;62:414-424. (Pubitemid 10094193)
30. Rosso R, Schafer D, Fricker R, et al. Functional and morphological outcome of knee joint transplantation in dogs depends on control of rejection. Transplantation 1997;63: 1723-1733. (Pubitemid 27278942)
31. Schäfer D, Rosso R, Fricker R, et al. Functional outcome of transplanted knee joints in dogs. Arch Orthop Trauma Surg. 2000;120:426-431. (Pubitemid 30453690)
32. Hofmann GO, Kirschner MH. Clinical experience in allogeneic vascularized bone and joint allografting. Microsurgery 2000;20:375-383. (Pubitemid 32044143)