Tim50 in Trypanosoma brucei possesses a dual specificity phosphatase activity and is critical for mitochondrial protein import

Journal of Biological Chemistry

Volumn 288, Issue 5, 2013, Pages 3184-3197

  Duncan, Melanie R ^a   Fullerton, Marjorie ^a   Chaudhuri, Minu ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACIDS; C TERMINUS; C-TERMINAL DOMAINS; CAUSATIVE AGENTS; COIMMUNOPRECIPITATION ANALYSIS; INNER MEMBRANES; MITOCHONDRIAL ACTIVITY; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEIN; N-TERMINALS; OVER-EXPRESSION; PARASITIC PROTOZOAN; PHOSPHATASE ACTIVITY; PREPROTEINS; TRANSLOCASES; TRYPANOSOMA BRUCEI; VOLTAGE-DEPENDENT ANION CHANNELS;

AMINO ACIDS; CELL MEMBRANES; INTERNATIONAL TRADE; MACHINERY; MITOCHONDRIA; PHOSPHATASES; PLANTS (BOTANY);

RECOMBINANT PROTEINS;

ALANINE; ASPARTIC ACID; CARRIER PROTEIN; MITOCHONDRIAL PROTEIN; PHOSPHATASE; PHOSPHOTYROSINE; PROTEIN SERINE THREONINE PHOSPHATE; PROTEIN TIM17; PROTEIN TIM50; PROTEIN TYROSINE PHOSPHATE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENE SILENCING; GROWTH INHIBITION; IMMUNOPRECIPITATION; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI;

ASPARTIC ACID; CELL NUCLEUS; CELL PROLIFERATION; DUAL-SPECIFICITY PHOSPHATASES; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOPRECIPITATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL PROTEINS; PROTEIN BINDING; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SUBCELLULAR FRACTIONS; TRYPANOSOMA BRUCEI BRUCEI; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84873289420     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.436378     Document Type: Article

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