Sensitive LC-MS/MS-ESI method for simultaneous determination of nifedipine and atenolol in human plasma and its application to a human pharmacokinetic study

Biomedical Chromatography

Volumn 27, Issue 3, 2013, Pages 349-355

  Kallem, Raja Reddy ^a   Inamadugu, Jaswanth Kumar ^b   Ramesh, Mullangi ^c   Seshagirirao, J V L N ^a  

^a ANDHRA UNIVERSITY   (India)

^b Wellquest Clinical Research Laboratories   (India)

^c JUBILANT BIOSYS LTD   (India)

Author keywords

Atenolol; Human plasma; LC MS MS; Method validation; Nifedipine; Pharmacokinetics

Indexed keywords

CARBOXYLIC ACIDS; PHARMACOKINETICS; PLASMA (HUMAN); PYRIDINE; SOLVENT EXTRACTION;

ATENOLOL; HUMAN PLASMAS; INTERNAL STANDARDS; ITS APPLICATIONS; LC-MS-MS; LC.MS/MS; METHOD VALIDATIONS; NIFEDIPINE; PHARMACOKINETIC STUDIES; SIMULTANEOUS DETERMINATIONS;

ELECTROSPRAY IONIZATION;

ATENOLOL; NIFEDIPINE;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN EXPERIMENT; IONIZATION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; STANDARD; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 84873276634     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2798     Document Type: Article

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