Small-world networks in individuals at ultra-high risk for psychosis and first-episode schizophrenia during a working memory task

Neuroscience Letters

Volumn 535, Issue 1, 2013, Pages 35-39

  Jhung, Kyungun ^a   Cho, Sung Hwan ^b   Jang, Ji Hyun ^b   Park, Jin Young ^c,e   Shin, Dongkwan ^b   Kim, Kyung Ran ^d,e   Lee, Eun ^d,e   Cho, Kwang Hyun ^b   An, Suk Kyoon ^d,e,f  

^a Konyang University College of Medicine   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f Yonsei University   (South Korea)

Author keywords

Electroencephalography; First episode schizophrenia; Small world network; Theta band; Ultra high risk for psychosis; Working memory

Indexed keywords

CHLORPROMAZINE; NEUROLEPTIC AGENT;

ADULT; ARTICLE; BRAIN FUNCTION; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE DURATION; EDUCATIONAL STATUS; ELECTROENCEPHALOGRAPHY; FEMALE; FIRST EPISODE SCHIZOPHRENIA; GENETIC RISK; HIGH RISK PATIENT; HUMAN; MALE; NEGATIVE SYNDROME; PATHOPHYSIOLOGY; POSITIVE SYNDROME; PRIORITY JOURNAL; SCHIZOPHRENIA; SCHIZOTYPAL PERSONALITY DISORDER; TASK PERFORMANCE; THETA RHYTHM; VERBAL MEMORY; WORKING MEMORY;

BRAIN; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NERVE NET; PSYCHOTIC DISORDERS; RISK; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; THETA RHYTHM; YOUNG ADULT;

EID: 84873266698     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.11.051     Document Type: Article

References (52)

1. Achard S., Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Computational Biology 2007, 3:e17.
2. Achard S., Salvador R., Whitcher B., Suckling J., Bullmore E. A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. Journal of Neuroscience 2006, 26:63-72.
3. Andreasen N.C. Scale for the Assessment of Negative Symptoms (SANS) 1983, University of Iowa, Iowa City.
4. Andreasen N.C. Scale for the Assessment of Positive Symptoms (SAPS) 1983, University of Iowa, Iowa City.
5. Andreasen N.C., Nopoulos P., O'Leary D.S., Miller D.D., Wassink T., Flaum M. Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms. Biological Psychiatry 1999, 46:908-920.
6. Andreasen N.C., Paradiso S., O'Leary D.S. "Cognitive dysmetria" as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry?. Schizophrenia Bulletin 1998, 24:203-218.
7. Baddeley A. Working memory: looking back and looking forward. Nature Reviews Neuroscience 2003, 4:829-839.
8. Barrantes-Vidal N., Aguilera M., Campanera S., Fatjo-Vilas M., Guitart M., Miret S., Valero S., Fananas L. Working memory in siblings of schizophrenia patients. Schizophrenia Research 2007, 95:70-75.
9. Bassett D.S., Bullmore E. Small-world brain networks. Neuroscientist 2006, 12:512-523.
10. Bassett D.S., Meyer-Lindenberg A., Achard S., Duke T., Bullmore E. Adaptive reconfiguration of fractal small-world human brain functional networks. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:19518-19523.
11. Breakspear M., Terry J.R., Friston K.J., Harris A.W., Williams L.M., Brown K., Brennan J., Gordon E. A disturbance of nonlinear interdependence in scalp EEG of subjects with first episode schizophrenia. Neuroimage 2003, 20:466-478.
12. Brewer W.J., Wood S.J., Phillips L.J., Francey S.M., Pantelis C., Yung A.R., Cornblatt B., McGorry P.D. Generalized and specific cognitive performance in clinical high-risk cohorts: a review highlighting potential vulnerability markers for psychosis. Schizophrenia Bulletin 2006, 32:538-555.
13. Broome M.R., Matthiasson P., Fusar-Poli P., Woolley J.B., Johns L.C., Tabraham P., Bramon E., Valmaggia L., Williams S.C., Brammer M.J., Chitnis X., McGuire P.K. Neural correlates of executive function and working memory in the 'at-risk mental state'. British Journal of Psychiatry 2009, 194:25-33.
14. Cannon T.D., Cadenhead K., Cornblatt B., Woods S.W., Addington J., Walker E., Seidman L.J., Perkins D., Tsuang M., McGlashan T., Heinssen R. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Archives of General Psychiatry 2008, 65:28-37.
15. Cannon T.D., Huttunen M.O., Lonnqvist J., Tuulio-Henriksson A., Pirkola T., Glahn D., Finkelstein J., Hietanen M., Kaprio J., Koskenvuo M. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. American Journal of Human Genetics 2000, 67:369-382.
16. Conklin H.M., Curtis C.E., Calkins M.E., Iacono W.G. Working memory functioning in schizophrenia patients and their first-degree relatives: cognitive functioning shedding light on etiology. Neuropsychologia 2005, 43:930-942.
17. Daban C., Amado I., Bourdel M.C., Loo H., Olie J.P., Poirier M.F., Krebs M.O. Cognitive dysfunctions in medicated and unmedicated patients with recent-onset schizophrenia. Journal of Psychiatric Research 2005, 39:391-398.
18. Danielyan A., Nasrallah H.A. Neurological disorders in schizophrenia. The Psychiatric Clinics of North America 2009, 32:719-757.
19. Delorme A., Makeig S. EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. Journal of Neuroscience Methods 2004, 134:9-21.
20. Douw L., Schoonheim M.M., Landi D., van der Meer M.L., Geurts J.J., Reijneveld J.C., Klein M., Stam C.J. Cognition is related to resting-state small-world network topology: an magnetoencephalographic study. Neuroscience 2011, 175:169-177.
21. First M.B., Gibbon M., Spitzer R.L., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders: Non-Patients Edition (SCID-I/PS) 1996, New York State Psychiatric Institute Biometrics Research, New York.
22. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders: Patient Edition (SCID-I/P) 1996, New York State Psychiatric Institute Biometrics Research, New York.
23. Fusar-Poli P., Broome M.R., Matthiasson P., Woolley J.B., Johns L.C., Tabraham P., Bramon E., Valmaggia L., Williams S.C., McGuire P. Spatial working memory in individuals at high risk for psychosis: longitudinal fMRI study. Schizophrenia Research 2010, 123:45-52.
24. Ginestet C.E., Simmons A. Statistical parametric network analysis of functional connectivity dynamics during a working memory task. Neuroimage 2011, 55:688-704.
25. Green M.F. Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. Journal of Clinical Psychiatry 2006, 67:e12.
26. Hasselmo M.E. What is the function of hippocampal theta rhythm? - linking behavioral data to phasic properties of field potential and unit recording data. Hippocampus 2005, 15:936-949.
27. Hoaglin D., Mosteller F., Tukey J. Understanding Robust and Exploratory Data Analysis 1983, Wiley, New York.
28. Humphries M.D., Gurney K., Prescott T.J. The brainstem reticular formation is a small-world, not scale-free, network. Proceedings Biological Science 2006, 273:503-511.
29. Javitt D.C. When doors of perception close: bottom-up models of disrupted cognition in schizophrenia. Annual Review of Clinical Psychology 2009, 5:249-275.
30. Karlsgodt K.H., Glahn D.C., van Erp T.G., Therman S., Huttunen M., Manninen M., Kaprio J., Cohen M.S., Lonnqvist J., Cannon T.D. The relationship between performance and fMRI signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects. Schizophrenia Research 2007, 89:191-197.
31. Keefe R.S. Working Memory Dysfunction and Its Relevance in Schizophrenia 2000, Oxford University Press, Oxford, pp. 16-49.
32. Kim K.R., Park J.Y., Song D.H., Koo H.K., An S.K. Neurocognitive performance in subjects at ultrahigh risk for schizophrenia: a comparison with first-episode schizophrenia. Comprehensive Psychiatry 2011, 52:33-40.
33. Klimesch W. Memory processes, brain oscillations and EEG synchronization. International Journal of Psychophysiology 1996, 24:61-100.
34. Krieger S., Lis S., Janik H., Cetin T., Gallhofer B., Meyer-Lindenberg A. Executive function and cognitive subprocesses in first-episode, drug-naive schizophrenia: an analysis of N-back performance. American Journal of Psychiatry 2005, 162:1206-1208.
35. Kroken R.A., Johnsen E., Rudd T., Wentzel-Larsen T., Jorgensen H.A. Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study. BMC Psychiatry 2009, 9:24.
36. Lee S.Y., Namkoong K., Cho H.H., Song D.H., An S.K. Reduced visual P300 amplitudes in individuals at ultra-high risk for psychosis and first-episode schizophrenia. Neuroscience Letters 2010, 486:156-160.
37. Liu Y., Liang M., Zhou Y., He Y., Hao Y., Song M., Yu C., Liu H., Liu Z., Jiang T. Disrupted small-world networks in schizophrenia. Brain 2008, 131:945-961.
38. Micheloyannis S., Pachou E., Stam C.J., Breakspear M., Bitsios P., Vourkas M., Erimaki S., Zervakis M. Small-world networks and disturbed functional connectivity in schizophrenia. Schizophrenia Research 2006, 87:60-66.
39. Miller T.J., McGlashan T.H., Rosen J.L., Cadenhead K., Cannon T., Ventura J., McFarlane W., Perkins D.O., Pearlson G.D., Woods S.W. Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability. Schizophrenia Bulletin 2003, 29:703-715.
40. Pachou E., Vourkas M., Simos P., Smit D., Stam C.J., Tsirka V., Micheloyannis S. Working memory in schizophrenia: an EEG study using power spectrum and coherence analysis to estimate cortical activation and network behavior. Brain Topography 2008, 21:128-137.
41. Rubinov M., Knock S.A., Stam C.J., Micheloyannis S., Harris A.W., Williams L.M., Breakspear M. Small-world properties of nonlinear brain activity in schizophrenia. Human Brain Mapping 2009, 30:403-416.
42. Ruhrmann S., Schultze-Lutter F., Salokangas R.K., Heinimaa M., Linszen D., Dingemans P., Birchwood M., Patterson P., Juckel G., Heinz A., Morrison A., Lewis S., von Reventlow H.G., Klosterkotter J. Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study. Archives of General Psychiatry 2010, 67:241-251.
43. Schmiedt C., Brand A., Hildebrandt H., Basar-Eroglu C. Event-related theta oscillations during working memory tasks in patients with schizophrenia and healthy controls. Brain Research. Cognitive Brain Research 2005, 25:936-947.
44. Sporns O., Zwi J.D. The small world of the cerebral cortex. Neuroinformatics 2004, 2:145-162.
45. Stam C.J. Functional connectivity patterns of human magnetoencephalographic recordings: a 'small-world' network?. Neuroscience Letters 2004, 355:25-28.
46. Stam C.J., de Bruin E.A. Scale-free dynamics of global functional connectivity in the human brain. Human Brain Mapping 2004, 22:97-109.
47. Supekar K., Musen M., Menon V. Development of large-scale functional brain networks in children. PLoS Biology 2009, 7:e1000157.
48. Uhlhaas P.J., Haenschel C., Nikolic D., Singer W. The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia. Schizophrenia Bulletin 2008, 34:927-943.
49. von Stein A., Sarnthein J. Different frequencies for different scales of cortical integration: from local gamma to long range alpha/theta synchronization. International Journal of Psychophysiology 2000, 38:301-313.
50. Wagner M., Frommann I., Jessen F., Pukrop R., Bechdolf A., Ruhrmann S. Cognitive and neurobiological risk indicators in early and late prodromal stages. Schizophrenia Research 2006, 86:35-36.
51. Watts D.J., Strogatz S.H. Collective dynamics of 'small-world' networks. Nature 1998, 393:440-442.
52. Yung A.R., Nelson B., Stanford C., Simmons M.B., Cosgrave E.M., Killackey E., Phillips L.J., Bechdolf A., Buckby J., McGorry P.D. Validation of "prodromal" criteria to detect individuals at ultra high risk of psychosis: 2 year follow-up. Schizophrenia Research 2008, 105:10-17.