메뉴 건너뛰기




Volumn 42, Issue 1, 2013, Pages 149-164

Perinatal Programming of Metabolic Diseases. Role of Insulin in the Development of Hypothalamic Neurocircuits

Author keywords

Development; Glucose; Hypothalamus; Insulin; Maternal diabetes; Maternal obesity; Perinatal programming

Indexed keywords

INSULIN; INSULIN RECEPTOR;

EID: 84873261228     PISSN: 08898529     EISSN: 15584410     Source Type: Journal    
DOI: 10.1016/j.ecl.2012.10.002     Document Type: Review
Times cited : (25)

References (98)
  • 1
    • 15544369982 scopus 로고    scopus 로고
    • Developmental origins of the metabolic syndrome: prediction, plasticity, and programming
    • McMillen I.C., Robinson J.S. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005, 85(2):571-633.
    • (2005) Physiol Rev , vol.85 , Issue.2 , pp. 571-633
    • McMillen, I.C.1    Robinson, J.S.2
  • 2
    • 33745019169 scopus 로고    scopus 로고
    • Perinatal nutrition and hormone-dependent programming of food intake
    • Plagemann A. Perinatal nutrition and hormone-dependent programming of food intake. Horm Res 2006, 65(Suppl 3):83-89.
    • (2006) Horm Res , vol.65 , Issue.SUPPL 3 , pp. 83-89
    • Plagemann, A.1
  • 3
    • 33748328554 scopus 로고    scopus 로고
    • Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis
    • Levin B.E. Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis. Philos Trans R Soc Lond B Biol Sci 2006, 361(1471):1107-1121.
    • (2006) Philos Trans R Soc Lond B Biol Sci , vol.361 , Issue.1471 , pp. 1107-1121
    • Levin, B.E.1
  • 4
    • 78649507541 scopus 로고    scopus 로고
    • Early life nutrition and metabolic programming
    • Fernandez-Twinn D.S., Ozanne S.E. Early life nutrition and metabolic programming. Ann N Y Acad Sci 2010, 1212:78-96.
    • (2010) Ann N Y Acad Sci , vol.1212 , pp. 78-96
    • Fernandez-Twinn, D.S.1    Ozanne, S.E.2
  • 5
    • 53849092685 scopus 로고    scopus 로고
    • Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic
    • Wang Y., Beydoun M.A., Liang L., et al. Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic. Obesity (Silver Spring) 2008, 16(10):2323-2330.
    • (2008) Obesity (Silver Spring) , vol.16 , Issue.10 , pp. 2323-2330
    • Wang, Y.1    Beydoun, M.A.2    Liang, L.3
  • 6
    • 0037055715 scopus 로고    scopus 로고
    • Childhood obesity: public-health crisis, common sense cure
    • Ebbeling C.B., Pawlak D.B., Ludwig D.S. Childhood obesity: public-health crisis, common sense cure. Lancet 2002, 360(9331):473-482.
    • (2002) Lancet , vol.360 , Issue.9331 , pp. 473-482
    • Ebbeling, C.B.1    Pawlak, D.B.2    Ludwig, D.S.3
  • 7
    • 0035955029 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus in children: primary care and public health considerations
    • Ludwig D.S., Ebbeling C.B. Type 2 diabetes mellitus in children: primary care and public health considerations. JAMA 2001, 286(12):1427-1430.
    • (2001) JAMA , vol.286 , Issue.12 , pp. 1427-1430
    • Ludwig, D.S.1    Ebbeling, C.B.2
  • 8
    • 2942554887 scopus 로고    scopus 로고
    • Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002
    • Hedley A.A., Ogden C.L., Johnson C.L., et al. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004, 291(23):2847-2850.
    • (2004) JAMA , vol.291 , Issue.23 , pp. 2847-2850
    • Hedley, A.A.1    Ogden, C.L.2    Johnson, C.L.3
  • 10
    • 0029940891 scopus 로고    scopus 로고
    • Adolescent overweight is associated with adult overweight and related multiple cardiovascular risk factors: the Bogalusa Heart Study
    • Srinivasan S.R., Bao W., Wattigney W.A., et al. Adolescent overweight is associated with adult overweight and related multiple cardiovascular risk factors: the Bogalusa Heart Study. Metabolism 1996, 45(2):235-240.
    • (1996) Metabolism , vol.45 , Issue.2 , pp. 235-240
    • Srinivasan, S.R.1    Bao, W.2    Wattigney, W.A.3
  • 11
    • 0030967953 scopus 로고    scopus 로고
    • Predicting obesity in young adulthood from childhood and parental obesity
    • Whitaker R.C., Wright J.A., Pepe M.S., et al. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med 1997, 337(13):869-873.
    • (1997) N Engl J Med , vol.337 , Issue.13 , pp. 869-873
    • Whitaker, R.C.1    Wright, J.A.2    Pepe, M.S.3
  • 12
    • 0029588483 scopus 로고
    • Does adult-onset diabetes mellitus begin in childhood? The Bogalusa Heart Study
    • Berenson G.S., Radhakrishnamurthy B., Bao W., et al. Does adult-onset diabetes mellitus begin in childhood? The Bogalusa Heart Study. Am J Med Sci 1995, 310(Suppl 1):S77-S82.
    • (1995) Am J Med Sci , vol.310 , Issue.SUPPL 1
    • Berenson, G.S.1    Radhakrishnamurthy, B.2    Bao, W.3
  • 13
    • 0013969637 scopus 로고
    • Biological Freudianism. Lasting effects of early environmental influences
    • Dubos R., Savage D., Schaedler R. Biological Freudianism. Lasting effects of early environmental influences. Pediatrics 1966, 38(5):789-800.
    • (1966) Pediatrics , vol.38 , Issue.5 , pp. 789-800
    • Dubos, R.1    Savage, D.2    Schaedler, R.3
  • 14
    • 0024542325 scopus 로고
    • Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease
    • Barker D.J., Osmond C., Golding J., et al. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989, 298(6673):564-567.
    • (1989) BMJ , vol.298 , Issue.6673 , pp. 564-567
    • Barker, D.J.1    Osmond, C.2    Golding, J.3
  • 15
    • 0025375671 scopus 로고
    • Risk of death from cardiovascular disease and chronic bronchitis determined by place of birth in England and Wales
    • Osmond C., Barker D.J., Slattery J.M. Risk of death from cardiovascular disease and chronic bronchitis determined by place of birth in England and Wales. J Epidemiol Community Health 1990, 44(2):139-141.
    • (1990) J Epidemiol Community Health , vol.44 , Issue.2 , pp. 139-141
    • Osmond, C.1    Barker, D.J.2    Slattery, J.M.3
  • 16
    • 0026008824 scopus 로고
    • Fetal and infant growth and impaired glucose tolerance at age 64
    • Hales C.N., Barker D.J., Clark P.M., et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 1991, 303(6809):1019-1022.
    • (1991) BMJ , vol.303 , Issue.6809 , pp. 1019-1022
    • Hales, C.N.1    Barker, D.J.2    Clark, P.M.3
  • 17
    • 0026772772 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis
    • Hales C.N., Barker D.J. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 1992, 35(7):595-601.
    • (1992) Diabetologia , vol.35 , Issue.7 , pp. 595-601
    • Hales, C.N.1    Barker, D.J.2
  • 18
    • 0029850959 scopus 로고    scopus 로고
    • Abnormal characteristics in young offspring of parents with non-insulin-dependent diabetes mellitus. The Bogalusa Heart Study
    • Berenson G.S., Bao W., Srinivasan S.R. Abnormal characteristics in young offspring of parents with non-insulin-dependent diabetes mellitus. The Bogalusa Heart Study. Am J Epidemiol 1996, 144(10):962-967.
    • (1996) Am J Epidemiol , vol.144 , Issue.10 , pp. 962-967
    • Berenson, G.S.1    Bao, W.2    Srinivasan, S.R.3
  • 19
    • 0035965661 scopus 로고    scopus 로고
    • Gestational diabetes mellitus
    • Jovanovic L., Pettitt D.J. Gestational diabetes mellitus. JAMA 2001, 286(20):2516-2518.
    • (2001) JAMA , vol.286 , Issue.20 , pp. 2516-2518
    • Jovanovic, L.1    Pettitt, D.J.2
  • 20
    • 0030981116 scopus 로고    scopus 로고
    • Overweight and obesity in infants of mothers with long-term insulin-dependent diabetes or gestational diabetes
    • Plagemann A., Harder T., Kohlhoff R., et al. Overweight and obesity in infants of mothers with long-term insulin-dependent diabetes or gestational diabetes. Int J Obes Relat Metab Disord 1997, 21(6):451-456.
    • (1997) Int J Obes Relat Metab Disord , vol.21 , Issue.6 , pp. 451-456
    • Plagemann, A.1    Harder, T.2    Kohlhoff, R.3
  • 21
    • 0022960596 scopus 로고
    • Ultrasound studies on fetal crown-rump length in early normal and diabetic pregnancy
    • Pedersen J.F. Ultrasound studies on fetal crown-rump length in early normal and diabetic pregnancy. Dan Med Bull 1986, 33(6):296-304.
    • (1986) Dan Med Bull , vol.33 , Issue.6 , pp. 296-304
    • Pedersen, J.F.1
  • 22
    • 20344382306 scopus 로고    scopus 로고
    • Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus
    • Boney C.M., Verma A., Tucker R., et al. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics 2005, 115(3):e290-e296.
    • (2005) Pediatrics , vol.115 , Issue.3
    • Boney, C.M.1    Verma, A.2    Tucker, R.3
  • 23
    • 34250672038 scopus 로고    scopus 로고
    • The role of family and maternal factors in childhood obesity
    • Gibson L.Y., Byrne S.M., Davis E.A., et al. The role of family and maternal factors in childhood obesity. Med J Aust 2007, 186(11):591-595.
    • (2007) Med J Aust , vol.186 , Issue.11 , pp. 591-595
    • Gibson, L.Y.1    Byrne, S.M.2    Davis, E.A.3
  • 24
    • 9644296438 scopus 로고    scopus 로고
    • Developmental origins of adult health and disease
    • Barker D.J. Developmental origins of adult health and disease. J Epidemiol Community Health 2004, 58(2):114-115.
    • (2004) J Epidemiol Community Health , vol.58 , Issue.2 , pp. 114-115
    • Barker, D.J.1
  • 25
    • 0036627597 scopus 로고    scopus 로고
    • Multiple neural systems controlling food intake and body weight
    • Berthoud H.R. Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 2002, 26(4):393-428.
    • (2002) Neurosci Biobehav Rev , vol.26 , Issue.4 , pp. 393-428
    • Berthoud, H.R.1
  • 26
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: hypothalamic control of food intake and body weight
    • Elmquist J.K., Elias C.F., Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999, 22(2):221-232.
    • (1999) Neuron , vol.22 , Issue.2 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 27
    • 68949120737 scopus 로고    scopus 로고
    • Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond
    • Konner A.C., Klockener T., Bruning J.C. Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond. Physiol Behav 2009, 97(5):632-638.
    • (2009) Physiol Behav , vol.97 , Issue.5 , pp. 632-638
    • Konner, A.C.1    Klockener, T.2    Bruning, J.C.3
  • 28
    • 27744436291 scopus 로고    scopus 로고
    • Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis
    • Elmquist J.K., Coppari R., Balthasar N., et al. Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis. J Comp Neurol 2005, 493(1):63-71.
    • (2005) J Comp Neurol , vol.493 , Issue.1 , pp. 63-71
    • Elmquist, J.K.1    Coppari, R.2    Balthasar, N.3
  • 29
    • 71949104669 scopus 로고    scopus 로고
    • Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus
    • Ciofi P., Garret M., Lapirot O., et al. Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus. Endocrinology 2009, 150(12):5509-5519.
    • (2009) Endocrinology , vol.150 , Issue.12 , pp. 5509-5519
    • Ciofi, P.1    Garret, M.2    Lapirot, O.3
  • 30
    • 1642349297 scopus 로고    scopus 로고
    • Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice
    • Bouret S.G., Draper S.J., Simerly R.B. Formation of projection pathways from the arcuate nucleus of the hypothalamus to hypothalamic regions implicated in the neural control of feeding behavior in mice. J Neurosci 2004, 24(11):2797-2805.
    • (2004) J Neurosci , vol.24 , Issue.11 , pp. 2797-2805
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 31
    • 34250199854 scopus 로고    scopus 로고
    • Prenatal development of hypothalamic neuropeptide systems in the nonhuman primate
    • Grayson B.E., Allen S.E., Billes S.K., et al. Prenatal development of hypothalamic neuropeptide systems in the nonhuman primate. Neuroscience 2006, 143(4):975-986.
    • (2006) Neuroscience , vol.143 , Issue.4 , pp. 975-986
    • Grayson, B.E.1    Allen, S.E.2    Billes, S.K.3
  • 33
    • 0022484472 scopus 로고
    • The development of the rat hypothalamus
    • Altman J., Bayer S. The development of the rat hypothalamus. Adv Anat Embryol Cell Biol 1986, 100(100):178.
    • (1986) Adv Anat Embryol Cell Biol , vol.100 , Issue.100 , pp. 178
    • Altman, J.1    Bayer, S.2
  • 34
    • 0015296012 scopus 로고
    • An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei
    • Ifft J.D. An autoradiographic study of the time of final division of neurons in rat hypothalamic nuclei. J Comp Neurol 1972, 144(2):193-204.
    • (1972) J Comp Neurol , vol.144 , Issue.2 , pp. 193-204
    • Ifft, J.D.1
  • 35
    • 0015893505 scopus 로고
    • Time of neuron origin in mouse hypothalamic nuclei
    • Shimada M., Nakamura T. Time of neuron origin in mouse hypothalamic nuclei. Exp Neurol 1973, 41(1):163-173.
    • (1973) Exp Neurol , vol.41 , Issue.1 , pp. 163-173
    • Shimada, M.1    Nakamura, T.2
  • 36
    • 77950547451 scopus 로고    scopus 로고
    • POMC-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits
    • Padilla S.L., Carmody J.S., Zeltser L.M. POMC-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits. Nat Med 2010, 16(4):403-405.
    • (2010) Nat Med , vol.16 , Issue.4 , pp. 403-405
    • Padilla, S.L.1    Carmody, J.S.2    Zeltser, L.M.3
  • 37
    • 84864389230 scopus 로고    scopus 로고
    • Embryonic birthdate of hypothalamic leptin-activated neurons in mice
    • Ishii Y., Bouret S.G. Embryonic birthdate of hypothalamic leptin-activated neurons in mice. Endocrinology 2012, 153:3657-3667.
    • (2012) Endocrinology , vol.153 , pp. 3657-3667
    • Ishii, Y.1    Bouret, S.G.2
  • 38
    • 0035000913 scopus 로고    scopus 로고
    • Ontogenetic development of the diencephalic MCH neurons: a hypothalamic 'MCH area' hypothesis
    • Brischoux F., Fellmann D., Risold P.Y. Ontogenetic development of the diencephalic MCH neurons: a hypothalamic 'MCH area' hypothesis. Eur J Neurosci 2001, 13(9):1733-1744.
    • (2001) Eur J Neurosci , vol.13 , Issue.9 , pp. 1733-1744
    • Brischoux, F.1    Fellmann, D.2    Risold, P.Y.3
  • 39
    • 0024408935 scopus 로고
    • Ontogeny of thyrotropin-releasing hormone gene expression in the rat diencephalon
    • Burgunder J.M., Taylor T. Ontogeny of thyrotropin-releasing hormone gene expression in the rat diencephalon. Neuroendocrinology 1989, 49(6):631-640.
    • (1989) Neuroendocrinology , vol.49 , Issue.6 , pp. 631-640
    • Burgunder, J.M.1    Taylor, T.2
  • 40
    • 0021716664 scopus 로고
    • Immunohistochemical study on the development of CRF-containing neurons in the hypothalamus of the rat
    • Daikoku S., Okamura Y., Kawano H., et al. Immunohistochemical study on the development of CRF-containing neurons in the hypothalamus of the rat. Cell Tissue Res 1984, 238(3):539-544.
    • (1984) Cell Tissue Res , vol.238 , Issue.3 , pp. 539-544
    • Daikoku, S.1    Okamura, Y.2    Kawano, H.3
  • 41
    • 0024459507 scopus 로고
    • Development of the spinal projections of the nucleus paraventricularis hypothalami of the rat: an intra-uterine WGA-HRP study
    • Lakke E.A., Hinderink J.B. Development of the spinal projections of the nucleus paraventricularis hypothalami of the rat: an intra-uterine WGA-HRP study. Brain Res Dev Brain Res 1989, 49(1):115-121.
    • (1989) Brain Res Dev Brain Res , vol.49 , Issue.1 , pp. 115-121
    • Lakke, E.A.1    Hinderink, J.B.2
  • 42
    • 0027481435 scopus 로고
    • Effect of paraventricular injection of neuropeptide Y on milk and water intake of preweanling rats
    • Capuano C.A., Leibowitz S.F., Barr G.A. Effect of paraventricular injection of neuropeptide Y on milk and water intake of preweanling rats. Neuropeptides 1993, 24(3):177-182.
    • (1993) Neuropeptides , vol.24 , Issue.3 , pp. 177-182
    • Capuano, C.A.1    Leibowitz, S.F.2    Barr, G.A.3
  • 43
    • 0032032575 scopus 로고    scopus 로고
    • Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function
    • Ahima R.S., Prabakaran D., Flier J.S. Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest 1998, 101(5):1020-1027.
    • (1998) J Clin Invest , vol.101 , Issue.5 , pp. 1020-1027
    • Ahima, R.S.1    Prabakaran, D.2    Flier, J.S.3
  • 44
    • 0018762428 scopus 로고
    • Cyto- and synaptogenesis in the arcuate nucleus of the rat hypothalamus during fetal and early postnatal life
    • Koritsanszky S. Cyto- and synaptogenesis in the arcuate nucleus of the rat hypothalamus during fetal and early postnatal life. Cell Tissue Res 1979, 200(1):135-146.
    • (1979) Cell Tissue Res , vol.200 , Issue.1 , pp. 135-146
    • Koritsanszky, S.1
  • 45
    • 0017062593 scopus 로고
    • Developmental changes in synaptic formation in the hypothalamic arcuate nucleus of female rats
    • Matsumoto A., Arai Y. Developmental changes in synaptic formation in the hypothalamic arcuate nucleus of female rats. Cell Tissue Res 1976, 169(2):143-156.
    • (1976) Cell Tissue Res , vol.169 , Issue.2 , pp. 143-156
    • Matsumoto, A.1    Arai, Y.2
  • 46
    • 77956173468 scopus 로고    scopus 로고
    • Neurodevelopmental actions of leptin
    • Bouret S.G. Neurodevelopmental actions of leptin. Brain Res 2010, 1350:2-9.
    • (2010) Brain Res , vol.1350 , pp. 2-9
    • Bouret, S.G.1
  • 47
    • 34547774572 scopus 로고    scopus 로고
    • Roles of leptin in prenatal and perinatal brain development
    • Udagawa J., Hatta T., Hashimoto R., et al. Roles of leptin in prenatal and perinatal brain development. Congenit Anom (Kyoto) 2007, 47(3):77-83.
    • (2007) Congenit Anom (Kyoto) , vol.47 , Issue.3 , pp. 77-83
    • Udagawa, J.1    Hatta, T.2    Hashimoto, R.3
  • 48
    • 2342457712 scopus 로고    scopus 로고
    • Beta cell differentiation during early human pancreas development
    • Piper K., Brickwood S., Turnpenny L.W., et al. Beta cell differentiation during early human pancreas development. J Endocrinol 2004, 181(1):11-23.
    • (2004) J Endocrinol , vol.181 , Issue.1 , pp. 11-23
    • Piper, K.1    Brickwood, S.2    Turnpenny, L.W.3
  • 49
    • 0015365495 scopus 로고
    • Insulin secretion during development: response of isolated pancreatic islets of fetal, newborn and adult rats to theophylline and arginine
    • Heinze E., Steinke J. Insulin secretion during development: response of isolated pancreatic islets of fetal, newborn and adult rats to theophylline and arginine. Horm Metab Res 1972, 4(4):234-236.
    • (1972) Horm Metab Res , vol.4 , Issue.4 , pp. 234-236
    • Heinze, E.1    Steinke, J.2
  • 50
    • 0032088869 scopus 로고    scopus 로고
    • Development of the insulin secretion mechanism in fetal and neonatal rat pancreatic B-cells: response to glucose, K+, theophylline, and carbamylcholine
    • Mendonca A.C., Carneiro E.M., Bosqueiro J.R., et al. Development of the insulin secretion mechanism in fetal and neonatal rat pancreatic B-cells: response to glucose, K+, theophylline, and carbamylcholine. Braz J Med Biol Res 1998, 31(6):841-846.
    • (1998) Braz J Med Biol Res , vol.31 , Issue.6 , pp. 841-846
    • Mendonca, A.C.1    Carneiro, E.M.2    Bosqueiro, J.R.3
  • 51
    • 0036822277 scopus 로고    scopus 로고
    • Placental glucose transfer and fetal growth
    • Baumann M.U., Deborde S., Illsley N.P. Placental glucose transfer and fetal growth. Endocrine 2002, 19(1):13-22.
    • (2002) Endocrine , vol.19 , Issue.1 , pp. 13-22
    • Baumann, M.U.1    Deborde, S.2    Illsley, N.P.3
  • 52
    • 82355163466 scopus 로고    scopus 로고
    • Placental transport in pregnancy pathologies
    • Desoye G., Gauster M., Wadsack C. Placental transport in pregnancy pathologies. Am J Clin Nutr 2011, 94(Suppl 6):1896S-1902S.
    • (2011) Am J Clin Nutr , vol.94 , Issue.SUPPL 6
    • Desoye, G.1    Gauster, M.2    Wadsack, C.3
  • 53
    • 0014977948 scopus 로고
    • Diabetes mellitus and pregnancy: present status of the hyperglycaemia-hyperinsulinism theory and the weight of the newborn baby
    • Pedersen J. Diabetes mellitus and pregnancy: present status of the hyperglycaemia-hyperinsulinism theory and the weight of the newborn baby. Postgrad Med J 1971, (Suppl):66-67.
    • (1971) Postgrad Med J , Issue.SUPPL , pp. 66-67
    • Pedersen, J.1
  • 54
    • 0003124325 scopus 로고
    • Hyperglycemia as the cause of characteristic features of the foetus and newborn of diabetic mothers
    • Pedersen J., Osler M. Hyperglycemia as the cause of characteristic features of the foetus and newborn of diabetic mothers. Dan Med Bull 1961, 8:78-83.
    • (1961) Dan Med Bull , vol.8 , pp. 78-83
    • Pedersen, J.1    Osler, M.2
  • 55
    • 0026333053 scopus 로고
    • Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation
    • Gauguier D., Bihoreau M.T., Picon L., et al. Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation. Diabetes 1991, 40(Suppl 2):109-114.
    • (1991) Diabetes , vol.40 , Issue.SUPPL 2 , pp. 109-114
    • Gauguier, D.1    Bihoreau, M.T.2    Picon, L.3
  • 56
    • 3242785787 scopus 로고    scopus 로고
    • Intrauterine hyperglycemia increases insulin binding sites but not glucose transporter expression in discrete brain areas in term rat fetuses
    • Leloup C., Magnan C., Alquier T., et al. Intrauterine hyperglycemia increases insulin binding sites but not glucose transporter expression in discrete brain areas in term rat fetuses. Pediatr Res 2004, 56(2):263-267.
    • (2004) Pediatr Res , vol.56 , Issue.2 , pp. 263-267
    • Leloup, C.1    Magnan, C.2    Alquier, T.3
  • 57
    • 0032556676 scopus 로고    scopus 로고
    • Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats
    • Plagemann A., Harder T., Rake A., et al. Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats. Neuroreport 1998, 9(18):4069-4073.
    • (1998) Neuroreport , vol.9 , Issue.18 , pp. 4069-4073
    • Plagemann, A.1    Harder, T.2    Rake, A.3
  • 58
    • 0033035278 scopus 로고    scopus 로고
    • Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes
    • Plagemann A., Harder T., Janert U., et al. Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes. Dev Neurosci 1999, 21(1):58-67.
    • (1999) Dev Neurosci , vol.21 , Issue.1 , pp. 58-67
    • Plagemann, A.1    Harder, T.2    Janert, U.3
  • 59
    • 67449152696 scopus 로고    scopus 로고
    • Hypothalamic alterations in fetuses of high fat diet-fed obese female rats
    • Gupta A., Srinivasan M., Thamadilok S., et al. Hypothalamic alterations in fetuses of high fat diet-fed obese female rats. J Endocrinol 2009, 200(3):293-300.
    • (2009) J Endocrinol , vol.200 , Issue.3 , pp. 293-300
    • Gupta, A.1    Srinivasan, M.2    Thamadilok, S.3
  • 60
    • 0016244208 scopus 로고
    • Fetal effects of maternal streptozotocin-diabetes
    • Pitkin R.M., Van Orden D.E. Fetal effects of maternal streptozotocin-diabetes. Endocrinology 1974, 94(5):1247-1253.
    • (1974) Endocrinology , vol.94 , Issue.5 , pp. 1247-1253
    • Pitkin, R.M.1    Van Orden, D.E.2
  • 61
    • 54349098711 scopus 로고    scopus 로고
    • Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism
    • Chen H., Simar D., Lambert K., et al. Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism. Endocrinology 2008, 149(11):5348-5356.
    • (2008) Endocrinology , vol.149 , Issue.11 , pp. 5348-5356
    • Chen, H.1    Simar, D.2    Lambert, K.3
  • 62
    • 0021330184 scopus 로고
    • Insulin binding in four regions of the developing rat brain
    • Kappy M., Sellinger S., Raizada M. Insulin binding in four regions of the developing rat brain. J Neurochem 1984, 42(1):198-203.
    • (1984) J Neurochem , vol.42 , Issue.1 , pp. 198-203
    • Kappy, M.1    Sellinger, S.2    Raizada, M.3
  • 63
    • 0025979940 scopus 로고
    • Expression of IGF-I and insulin receptor genes in the rat central nervous system: a developmental, regional, and cellular analysis
    • Baron-Van Evercooren A., Olichon-Berthe C., Kowalski A., et al. Expression of IGF-I and insulin receptor genes in the rat central nervous system: a developmental, regional, and cellular analysis. J Neurosci Res 1991, 28(2):244-253.
    • (1991) J Neurosci Res , vol.28 , Issue.2 , pp. 244-253
    • Baron-Van Evercooren, A.1    Olichon-Berthe, C.2    Kowalski, A.3
  • 64
    • 0023937644 scopus 로고
    • Developmental aspects of the rat brain insulin receptor: loss of sialic acid and fluctuation in number characterize fetal development
    • Brennan W.A. Developmental aspects of the rat brain insulin receptor: loss of sialic acid and fluctuation in number characterize fetal development. Endocrinology 1988, 122(6):2364-2370.
    • (1988) Endocrinology , vol.122 , Issue.6 , pp. 2364-2370
    • Brennan, W.A.1
  • 65
    • 0020541805 scopus 로고
    • Permeability of the blood-brain barrier in the median eminence during the perinatal period in rats
    • Ugrumov M.V., Ivanova I.P., Mitskevich M.S. Permeability of the blood-brain barrier in the median eminence during the perinatal period in rats. Cell Tissue Res 1983, 230(3):649-660.
    • (1983) Cell Tissue Res , vol.230 , Issue.3 , pp. 649-660
    • Ugrumov, M.V.1    Ivanova, I.P.2    Mitskevich, M.S.3
  • 66
    • 0031039392 scopus 로고    scopus 로고
    • Maternal diabetes-induced hyperglycemia and acute intracerebral hyperinsulinism suppress fetal brain neuropeptide Y concentrations
    • Singh B.S., Westfall T.C., Devaskar S.U. Maternal diabetes-induced hyperglycemia and acute intracerebral hyperinsulinism suppress fetal brain neuropeptide Y concentrations. Endocrinology 1997, 138(3):963-969.
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 963-969
    • Singh, B.S.1    Westfall, T.C.2    Devaskar, S.U.3
  • 67
    • 58149490989 scopus 로고    scopus 로고
    • Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth
    • Morris M.J., Chen H. Established maternal obesity in the rat reprograms hypothalamic appetite regulators and leptin signaling at birth. Int J Obes (Lond) 2009, 33(1):115-122.
    • (2009) Int J Obes (Lond) , vol.33 , Issue.1 , pp. 115-122
    • Morris, M.J.1    Chen, H.2
  • 68
    • 79952003081 scopus 로고    scopus 로고
    • Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny
    • Carmody J.S., Wan P., Accili D., et al. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity (Silver Spring) 2011, 19(3):492-499.
    • (2011) Obesity (Silver Spring) , vol.19 , Issue.3 , pp. 492-499
    • Carmody, J.S.1    Wan, P.2    Accili, D.3
  • 69
    • 80054927541 scopus 로고    scopus 로고
    • Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring
    • Steculorum S.M., Bouret S.G. Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring. Endocrinology 2011, 152:4171-4179.
    • (2011) Endocrinology , vol.152 , pp. 4171-4179
    • Steculorum, S.M.1    Bouret, S.G.2
  • 70
    • 79959786959 scopus 로고    scopus 로고
    • Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin
    • Desai M., Li T., Ross M.G. Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin. Endocrinology 2011, 152(8):3192-3201.
    • (2011) Endocrinology , vol.152 , Issue.8 , pp. 3192-3201
    • Desai, M.1    Li, T.2    Ross, M.G.3
  • 71
    • 84863057288 scopus 로고    scopus 로고
    • InsR/FoxO1 signaling curtails hypothalamic POMC neuron number
    • Plum L., Lin H.V., Aizawa K.S., et al. InsR/FoxO1 signaling curtails hypothalamic POMC neuron number. PLoS One 2012, 7(2):e31487.
    • (2012) PLoS One , vol.7 , Issue.2
    • Plum, L.1    Lin, H.V.2    Aizawa, K.S.3
  • 72
    • 0033528287 scopus 로고    scopus 로고
    • Increased number of galanin-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling rats
    • Plagemann A., Harder T., Rake A., et al. Increased number of galanin-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling rats. Brain Res 1999, 818(1):160-163.
    • (1999) Brain Res , vol.818 , Issue.1 , pp. 160-163
    • Plagemann, A.1    Harder, T.2    Rake, A.3
  • 73
    • 0032497125 scopus 로고    scopus 로고
    • Alterations of hypothalamic catecholamines in the newborn offspring of gestational diabetic mother rats
    • Plagemann A., Harder T., Lindner R., et al. Alterations of hypothalamic catecholamines in the newborn offspring of gestational diabetic mother rats. Brain Res Dev Brain Res 1998, 109(2):201-209.
    • (1998) Brain Res Dev Brain Res , vol.109 , Issue.2 , pp. 201-209
    • Plagemann, A.1    Harder, T.2    Lindner, R.3
  • 74
    • 1542355406 scopus 로고    scopus 로고
    • Prevention by maternal pancreatic islet transplantation of hypothalamic malformation in offspring of diabetic mother rats is already detectable at weaning
    • Harder T., Franke K., Fahrenkrog S., et al. Prevention by maternal pancreatic islet transplantation of hypothalamic malformation in offspring of diabetic mother rats is already detectable at weaning. Neurosci Lett 2003, 352(3):163-166.
    • (2003) Neurosci Lett , vol.352 , Issue.3 , pp. 163-166
    • Harder, T.1    Franke, K.2    Fahrenkrog, S.3
  • 75
    • 0035895701 scopus 로고    scopus 로고
    • Pancreatic islet transplantation in diabetic pregnant rats prevents acquired malformation of the ventromedial hypothalamic nucleus in their offspring
    • Harder T., Aerts L., Franke K., et al. Pancreatic islet transplantation in diabetic pregnant rats prevents acquired malformation of the ventromedial hypothalamic nucleus in their offspring. Neurosci Lett 2001, 299(1-2):85-88.
    • (2001) Neurosci Lett , vol.299 , Issue.1-2 , pp. 85-88
    • Harder, T.1    Aerts, L.2    Franke, K.3
  • 76
    • 19944429860 scopus 로고    scopus 로고
    • 'Programming' of orexigenic and anorexigenic hypothalamic neurons in offspring of treated and untreated diabetic mother rats
    • Franke K., Harder T., Aerts L., et al. 'Programming' of orexigenic and anorexigenic hypothalamic neurons in offspring of treated and untreated diabetic mother rats. Brain Res 2005, 1031(2):276-283.
    • (2005) Brain Res , vol.1031 , Issue.2 , pp. 276-283
    • Franke, K.1    Harder, T.2    Aerts, L.3
  • 77
    • 1542347160 scopus 로고    scopus 로고
    • Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism
    • Fahrenkrog S., Harder T., Stolaczyk E., et al. Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism. J Nutr 2004, 134(3):648-654.
    • (2004) J Nutr , vol.134 , Issue.3 , pp. 648-654
    • Fahrenkrog, S.1    Harder, T.2    Stolaczyk, E.3
  • 78
    • 0032851629 scopus 로고    scopus 로고
    • Brain endogenous insulin effects on neurite growth within fetal rat neuron cell cultures
    • Schechter R., Abboud M., Johnson G. Brain endogenous insulin effects on neurite growth within fetal rat neuron cell cultures. Brain Res Dev Brain Res 1999, 116(2):159-167.
    • (1999) Brain Res Dev Brain Res , vol.116 , Issue.2 , pp. 159-167
    • Schechter, R.1    Abboud, M.2    Johnson, G.3
  • 79
    • 0023922968 scopus 로고
    • Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors?
    • Toran-Allerand C.D., Ellis L., Pfenninger K.H. Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors?. Brain Res 1988, 469(1-2):87-100.
    • (1988) Brain Res , vol.469 , Issue.1-2 , pp. 87-100
    • Toran-Allerand, C.D.1    Ellis, L.2    Pfenninger, K.H.3
  • 80
    • 0033040270 scopus 로고    scopus 로고
    • Overweight and increased diabetes susceptibility in neonatally insulin-treated adult rats
    • Harder T., Rake A., Rohde W., et al. Overweight and increased diabetes susceptibility in neonatally insulin-treated adult rats. Endocr Regul 1999, 33(1):25-31.
    • (1999) Endocr Regul , vol.33 , Issue.1 , pp. 25-31
    • Harder, T.1    Rake, A.2    Rohde, W.3
  • 81
    • 0026653389 scopus 로고
    • Lifelong enhanced diabetes susceptibility and obesity after temporary intrahypothalamic hyperinsulinism during brain organization
    • Plagemann A., Heidrich I., Gotz F., et al. Lifelong enhanced diabetes susceptibility and obesity after temporary intrahypothalamic hyperinsulinism during brain organization. Exp Clin Endocrinol 1992, 99(2):91-95.
    • (1992) Exp Clin Endocrinol , vol.99 , Issue.2 , pp. 91-95
    • Plagemann, A.1    Heidrich, I.2    Gotz, F.3
  • 82
    • 0033018753 scopus 로고    scopus 로고
    • Morphological alterations of hypothalamic nuclei due to intrahypothalamic hyperinsulinism in newborn rats
    • Plagemann A., Harder T., Rake A., et al. Morphological alterations of hypothalamic nuclei due to intrahypothalamic hyperinsulinism in newborn rats. Int J Dev Neurosci 1999, 17(1):37-44.
    • (1999) Int J Dev Neurosci , vol.17 , Issue.1 , pp. 37-44
    • Plagemann, A.1    Harder, T.2    Rake, A.3
  • 83
    • 67649958535 scopus 로고    scopus 로고
    • Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring
    • Kirk S.L., Samuelsson A.M., Argenton M., et al. Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring. PLoS One 2009, 4(6):e5870.
    • (2009) PLoS One , vol.4 , Issue.6
    • Kirk, S.L.1    Samuelsson, A.M.2    Argenton, M.3
  • 84
    • 38749135486 scopus 로고    scopus 로고
    • Hypothalamic neural projections are permanently disrupted in diet-induced obese rats
    • Bouret S.G., Gorski J.N., Patterson C.M., et al. Hypothalamic neural projections are permanently disrupted in diet-induced obese rats. Cell Metab 2008, 7(2):179-185.
    • (2008) Cell Metab , vol.7 , Issue.2 , pp. 179-185
    • Bouret, S.G.1    Gorski, J.N.2    Patterson, C.M.3
  • 85
    • 78650014999 scopus 로고    scopus 로고
    • Organized for sex - steroid hormones and the developing hypothalamus
    • Lenz K.M., McCarthy M.M. Organized for sex - steroid hormones and the developing hypothalamus. Eur J Neurosci 2010, 32(12):2096-2104.
    • (2010) Eur J Neurosci , vol.32 , Issue.12 , pp. 2096-2104
    • Lenz, K.M.1    McCarthy, M.M.2
  • 86
    • 13844291281 scopus 로고    scopus 로고
    • Wired on hormones: endocrine regulation of hypothalamic development
    • Simerly R.B. Wired on hormones: endocrine regulation of hypothalamic development. Curr Opin Neurobiol 2005, 15(1):81-85.
    • (2005) Curr Opin Neurobiol , vol.15 , Issue.1 , pp. 81-85
    • Simerly, R.B.1
  • 88
    • 34247552309 scopus 로고    scopus 로고
    • Insulin resistance of hypothalamic arcuate neurons in neonatally overfed rats
    • Davidowa H., Plagemann A. Insulin resistance of hypothalamic arcuate neurons in neonatally overfed rats. Neuroreport 2007, 18(5):521-524.
    • (2007) Neuroreport , vol.18 , Issue.5 , pp. 521-524
    • Davidowa, H.1    Plagemann, A.2
  • 89
    • 67649808191 scopus 로고    scopus 로고
    • Differential responses of orexigenic neuropeptides to fasting in offspring of obese mothers
    • Chen H., Morris M.J. Differential responses of orexigenic neuropeptides to fasting in offspring of obese mothers. Obesity (Silver Spring) 2009, 17(7):1356-1362.
    • (2009) Obesity (Silver Spring) , vol.17 , Issue.7 , pp. 1356-1362
    • Chen, H.1    Morris, M.J.2
  • 90
    • 84856115639 scopus 로고    scopus 로고
    • Hypothalamic JNK1 and IKKbeta activation and impaired early postnatal glucose metabolism after maternal perinatal high-fat feeding
    • Rother E., Kuschewski R., Alcazar M.A., et al. Hypothalamic JNK1 and IKKbeta activation and impaired early postnatal glucose metabolism after maternal perinatal high-fat feeding. Endocrinology 2012, 153(2):770-781.
    • (2012) Endocrinology , vol.153 , Issue.2 , pp. 770-781
    • Rother, E.1    Kuschewski, R.2    Alcazar, M.A.3
  • 91
    • 77950216899 scopus 로고    scopus 로고
    • Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet
    • Grayson B.E., Levasseur P.R., Williams S.M., et al. Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology 2010, 151(4):1622-1632.
    • (2010) Endocrinology , vol.151 , Issue.4 , pp. 1622-1632
    • Grayson, B.E.1    Levasseur, P.R.2    Williams, S.M.3
  • 92
    • 0346340020 scopus 로고    scopus 로고
    • Role of redox in fetal development and neonatal diseases
    • Dennery P.A. Role of redox in fetal development and neonatal diseases. Antioxid Redox Signal 2004, 6(1):147-153.
    • (2004) Antioxid Redox Signal , vol.6 , Issue.1 , pp. 147-153
    • Dennery, P.A.1
  • 93
    • 77956176210 scopus 로고    scopus 로고
    • Oxidative stress in development: nature or nurture?
    • Dennery P.A. Oxidative stress in development: nature or nurture?. Free Radic Biol Med 2010, 49(7):1147-1151.
    • (2010) Free Radic Biol Med , vol.49 , Issue.7 , pp. 1147-1151
    • Dennery, P.A.1
  • 94
  • 95
    • 0036535218 scopus 로고    scopus 로고
    • Organization of human hypothalamus in fetal development
    • Koutcherov Y., Mai J.K., Ashwell K.W., et al. Organization of human hypothalamus in fetal development. J Comp Neurol 2002, 446(4):301-324.
    • (2002) J Comp Neurol , vol.446 , Issue.4 , pp. 301-324
    • Koutcherov, Y.1    Mai, J.K.2    Ashwell, K.W.3
  • 96
    • 58149336861 scopus 로고    scopus 로고
    • Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity
    • Chang G.Q., Gaysinskaya V., Karatayev O., et al. Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J Neurosci 2008, 28(46):12107-12119.
    • (2008) J Neurosci , vol.28 , Issue.46 , pp. 12107-12119
    • Chang, G.Q.1    Gaysinskaya, V.2    Karatayev, O.3
  • 97
    • 0034122765 scopus 로고    scopus 로고
    • Glycemic control in the diabetic pregnancy: is tighter always better?
    • Rosenn B.M., Miodovnik M. Glycemic control in the diabetic pregnancy: is tighter always better?. J Matern Fetal Med 2000, 9(1):29-34.
    • (2000) J Matern Fetal Med , vol.9 , Issue.1 , pp. 29-34
    • Rosenn, B.M.1    Miodovnik, M.2
  • 98
    • 0036254603 scopus 로고    scopus 로고
    • Maternal hypoglycemia during pregnancy in type 1 diabetes: maternal and fetal consequences
    • ter Braak E.W., Evers I.M., Willem Erkelens D., et al. Maternal hypoglycemia during pregnancy in type 1 diabetes: maternal and fetal consequences. Diabetes Metab Res Rev 2002, 18(2):96-105.
    • (2002) Diabetes Metab Res Rev , vol.18 , Issue.2 , pp. 96-105
    • ter Braak, E.W.1    Evers, I.M.2    Willem Erkelens, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.