High-resolution 1050 nm spectral domain retinal optical coherence tomography at 120 kHz a-scan rate with 6.1 mm imaging depth

Biomedical Optics Express

Volumn 4, Issue 2, 2013, Pages 245-259

  An, Lin ^a   Li, Peng ^a   Lan, Gongpu ^a   Malchow, Doug ^b   Wang, Ruikang K ^a  

^a University of Washington   (United States)

^b GOODRICH CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSTRUCTURAL EVOLUTION; OPHTHALMOLOGY; PHASE STABILITY;

AXIAL RESOLUTIONS; BLOOD FLOW; HIGH RESOLUTION; HUMAN EYE; IMAGING DEPTH; IMAGING PERFORMANCE; IMAGING SPEED; MICROSTRUCTURAL FEATURES; POSTERIOR SEGMENT; RETINAL IMAGING; RETINAL OPTICAL COHERENCE TOMOGRAPHY; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHIES; SPECTRAL DOMAINS; SWEPT SOURCE OCT; SYSTEM SENSITIVITY;

OPTICAL TOMOGRAPHY;

EID: 84873250031     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.4.000245     Document Type: Article

References (60)

1. A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In vivo optical coherence tomography," Am. J. Ophthalmol. 116(1), 113-114 (1993).
2. P. H. Tomlins and R. K. Wang, "Theory, developments and applications of optical coherence tomography," J. Phys. D Appl. Phys. 38(15), 2519-2535 (2005).
3. C. K. Hitzenberger, P. Trost, P. W. Lo, and Q. Y. Zhou, "Three-dimensional imaging of the human retina by high-speed optical coherence tomography," Opt. Express 11(21), 2753-2761 (2003).
4. A. M. Rollins, S. Yazdanfar, M. Kulkarni, R. Ung-Arunyawee, and J. A. Izatt, "In vivo video rate optical coherence tomography," Opt. Express 3(6), 219-229 (1998).
5. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117(1-2), 43-48 (1995).
6. G. Häusler and M. W. Lindner, ""Coherence radar" and "spectral radar"-new tools for dermatological diagnosis," J. Biomed. Opt. 3(1), 21-31 (1998).
7. S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22(5), 340-342 (1997).
8. U. Haberland, P. Jansen, V. Blazek, and H. J. Schmitt, "Optical coherence tomography of scattering media using frequency-modulated continuous-wave techniques with tunable near-infrared laser," Proc. SPIE 2891, 20-28 (1997).
9. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11(8), 889-894 (2003).
10. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28(21), 2067-2069 (2003).
11. M. Choma, M. Sarunic, C. Yang, and J. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11(18), 2183-2189 (2003).
12. B. Cense, N. Nassif, T. Chen, M. Pierce, S.-H. Yun, B. Park, B. Bouma, G. Tearney, and J. de Boer, "Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography," Opt. Express 12(11), 2435-2447 (2004).
13. D. M. de Bruin, D. L. Burnes, J. Loewenstein, Y. Chen, S. Chang, T. C. Chen, D. D. Esmaili, and J. F. de Boer, "In vivo three-dimensional imaging of neovascular age-related macular degeneration using optical frequency domain imaging at 1050 nm," Invest. Ophthalmol. Vis. Sci. 49(10), 4545-4552 (2008).
14. E. C. Lee, J. F. de Boer, M. Mujat, H. Lim, and S. H. Yun, "In vivo optical frequency domain imaging of human retina and choroid," Opt. Express 14(10), 4403-4411 (2006).
15. H. Lim, M. Mujat, C. Kerbage, E. C. Lee, Y. Chen, T. C. Chen, and J. F. de Boer, "High-speed imaging of human retina in vivo with swept-source optical coherence tomography," Opt. Express 14(26), 12902-12908 (2006).
16. M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, and J. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12(11), 2404-2422 (2004).
17. R. A. Leitgeb, W. Drexler, A. Unterhuber, B. Hermann, T. Bajraszewski, T. Le, A. Stingl, and A. F. Fercher, "Ultrahigh resolution Fourier domain optical coherence tomography," Opt. Express 12(10), 2156-2165 (2004).
18. V. J. Srinivasan, R. Huber, I. Gorczynska, J. G. Fujimoto, J. Y. Jiang, P. Reisen, and A. E. Cable, "High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm," Opt. Lett. 32(4), 361-363 (2007).
19. A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels," Opt. Express 15(2), 408-422 (2007).
20. L. An and R. K. Wang, "In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography," Opt. Express 16(15), 11438-11452 (2008).
21. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, "Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging," Nat. Med. 15(10), 1219-1223 (2009).
22. B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical coherence tomography," Opt. Express 11(25), 3490-3497 (2003).
23. J. Fingler, R. J. Zawadzki, J. S. Werner, D. Schwartz, and S. E. Fraser, "Volumetric microvascular imaging of human retina using optical coherence tomography with a novel motion contrast technique," Opt. Express 17(24), 22190-22200 (2009).
24. L. An, H. M. Subhush, D. J. Wilson, and R. K. Wang, "High-resolution wide-field imaging of retinal and choroidal blood perfusion with optical microangiography," J. Biomed. Opt. 15(2), 026011 (2010).
25. L. Yu and Z. Chen, "Doppler variance imaging for three-dimensional retina and choroid angiography," J. Biomed. Opt. 15(1), 016029 (2010).
26. M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint spectral and time domain optical coherence tomography," Opt. Express 16(9), 6008-6025 (2008).
27. R. K. Wang, L. An, S. Saunders, and D. J. Wilson, "Optical microangiography provides depth-resolved images of directional ocular blood perfusion in posterior eye segment," J. Biomed. Opt. 15(2), 020502 (2010).
28. S. Makita, F. Jaillon, M. Yamanari, M. Miura, and Y. Yasuno, "Comprehensive in vivo micro-vascular imaging of the human eye by dual-beam-scan Doppler optical coherence angiography," Opt. Express 19(2), 1271-1283 (2011).
29. S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, "Optical coherence angiography," Opt. Express 14(17), 7821-7840 (2006).
30. B. Potsaid, B. Baumann, D. Huang, S. Barry, A. E. Cable, J. S. Schuman, J. S. Duker, and J. G. Fujimoto, "Ultrahigh speed 1050nm swept source/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second," Opt. Express 18(19), 20029-20048 (2010).
31. C. M. Eigenwillig, T. Klein, W. Wieser, B. R. Biedermann, and R. Huber, "Wavelength swept amplified spontaneous emission source for high speed retinal optical coherence tomography at 1060 nm," J Biophotonics 4(7-8), 552-558 (2011).
32. T. Klein, W. Wieser, C. M. Eigenwillig, B. R. Biedermann, and R. Huber, "Megahertz OCT for ultrawide-field retinal imaging with a 1050nm Fourier domain mode-locked laser," Opt. Express 19(4), 3044-3062 (2011).
33. M. Gora, K. Karnowski, M. Szkulmowski, B. J. Kaluzny, R. Huber, A. Kowalczyk, and M. Wojtkowski, "Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range," Opt. Express 17(17), 14880-14894 (2009).
34. V. J. Srinivasan, D. C. Adler, Y. Chen, I. Gorczynska, R. Huber, J. S. Duker, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head," Invest. Ophthalmol. Vis. Sci. 49(11), 5103-5110 (2008).
35. B. Potsaid, I. Gorczynska, V. J. Srinivasan, Y. L. Chen, J. Jiang, A. Cable, and J. G. Fujimoto, "Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second," Opt. Express 16(19), 15149-15169 (2008).
36. D. Y. Kim, J. Fingler, J. S. Werner, D. M. Schwartz, S. E. Fraser, and R. J. Zawadzki, "In vivo volumetric imaging of human retinal circulation with phase-variance optical coherence tomography," Biomed. Opt. Express 2(6), 1504-1513 (2011).
37. R. K. Wang, L. An, P. Francis, and D. J. Wilson, "Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography," Opt. Lett. 35(9), 1467-1469 (2010).
38. L. An, P. Li, T. T. Shen, and R. K. Wang, "High speed spectral domain optical coherence tomography for retinal imaging at 500,000 A-lines per second," Biomed. Opt. Express 2(10), 2770-2783 (2011).
39. Y. Wang, J. Nelson, Z. Chen, B. Reiser, R. Chuck, and R. Windeler, "Optimal wavelength for ultrahigh-resolution optical coherence tomography," Opt. Express 11(12), 1411-1417 (2003).
40. J. Xi, L. Huo, J. Li, and X. Li, "Generic real-time uniform K-space sampling method for high-speed swept-source optical coherence tomography," Opt. Express 18(9), 9511-9517 (2010).
41. W. Wieser, B. R. Biedermann, T. Klein, C. M. Eigenwillig, and R. Huber, "Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second," Opt. Express 18(14), 14685-14704 (2010).
42. R. K. Manapuram, V. G. R. Manne, and K. V. Larin, "Development of phase-stabilized swept-source OCT for the ultrasensitive quantification of microbubbles," Laser Phys. 18(9), 1080-1086 (2008).
43. H. C. Hendargo, R. P. McNabb, A. H. Dhalla, N. Shepherd, and J. A. Izatt, "Doppler velocity detection limitations in spectrometer-based versus swept-source optical coherence tomography," Biomed. Opt. Express 2(8), 2175-2188 (2011).
44. B. Braaf, K. A. Vermeer, V. A. Sicam, E. van Zeeburg, J. C. van Meurs, and J. F. de Boer, "Phase-stabilized optical frequency domain imaging at 1-μm for the measurement of blood flow in the human choroid," Opt. Express 19(21), 20886-20903 (2011).
45. B. J. Vakoc, S. H. Yun, J. F. de Boer, G. J. Tearney, and B. E. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13(14), 5483-5493 (2005).
46. J. Zhang and Z. Chen, "In vivo blood flow imaging by a swept laser source based Fourier domain optical Doppler tomography," Opt. Express 13(19), 7449-7457 (2005).
47. B. Baumann, B. Potsaid, M. F. Kraus, J. J. Liu, D. Huang, J. Hornegger, A. E. Cable, J. S. Duker, and J. G. Fujimoto, "Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT," Biomed. Opt. Express 2(6), 1539-1552 (2011).
48. Y. J. Hong, S. Makita, F. Jaillon, M. J. Ju, E. J. Min, B. H. Lee, M. Itoh, M. Miura, and Y. Yasuno, "High-penetration swept source Doppler optical coherence angiography by fully numerical phase stabilization," Opt. Express 20(3), 2740-2760 (2012).
49. R. K. Wang and L. An, "Multifunctional imaging of human retina and choroid with 1050-nm spectral domain optical coherence tomography at 92-kHz line scan rate," J. Biomed. Opt. 16(5), 050503 (2011).
50. American National Standard Institute," Safe use of lasers and safe use of optical fiber communications," (ANSI, New York; 2000), no. 168.
51. Y. Zhao, Z. Chen, Z. Ding, H. Ren, and J. S. Nelson, "Real-time phase-resolved functional optical coherence tomography by use of optical Hilbert transformation," Opt. Lett. 27(2), 98-100 (2002).
52. R. K. Wang and Z. Ma, "Real-time flow imaging by removing texture pattern artifacts in spectral-domain optical Doppler tomography," Opt. Lett. 31(20), 3001-3003 (2006).
53. R. K. Wang, Z. Ma, and S. J. Kirkpatrick, "Tissue Doppler optical coherence elastography for real time strain rate and strain mapping of soft tissue," Appl. Phys. Lett. 89, 3 (2006).
54. D. C. Adler, S. W. Huang, R. Huber, and J. G. Fujimoto, "Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography," Opt. Express 16(7), 4376-4393 (2008).
55. Y. Jung, R. Reif, Y. Zeng, and R. K. Wang, "Three-dimensional high-resolution imaging of gold nanorods uptake in sentinel lymph nodes," Nano Lett. 11(7), 2938-2943 (2011).
56. R. K. Wang and A. L. Nuttall, "Phase-sensitive optical coherence tomography imaging of the tissue motion within the organ of Corti at a subnanometer scale: a preliminary study," J. Biomed. Opt. 15(5), 056005 (2010).
57. G. Fuchsjäger-Mayrl, B. Wally, M. Georgopoulos, G. Rainer, K. Kircher, W. Buehl, T. Amoako-Mensah, H. G. Eichler, C. Vass, and L. Schmetterer, "Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension," Invest. Ophthalmol. Vis. Sci. 45(3), 834-839 (2004).
58. V. Patel, S. Rassam, R. Newsom, J. Wiek, and E. Kohner, "Retinal blood flow in diabetic retinopathy," BMJ 305(6855), 678-683 (1992).
59. E. Sato, G. T. Feke, M. N. Menke, and J. Wallace McMeel, "Retinal haemodynamics in patients with age-related macular degeneration," Eye (Lond.) 20(6), 697-702 (2006).
60. B. Rao, L. Yu, H. K. Chiang, L. C. Zacharias, R. M. Kurtz, B. D. Kuppermann, and Z. Chen, "Imaging pulsatile retinal blood flow in human eye," J. Biomed. Opt. 13(4), 040505 (2008).