High speed spectral domain optical coherence tomography for retinal imaging at 500,000 A-lines per second

Biomedical Optics Express

Volumn 2, Issue 10, 2011, Pages 2770-2783

  An, Lin ^a   Li, Peng ^a   Shen, Tueng T ^a,b   Wang, Ruikang ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CMOS INTEGRATED CIRCUITS; DEGRADATION; OPHTHALMOLOGY; OPTICAL TOMOGRAPHY; SIGNAL RECONSTRUCTION;

3D DATA; 3D IMAGING; AXIAL RESOLUTIONS; B-FRAME; CENTRAL WAVELENGTH; CMOS CAMERA; DEPTH-RESOLVED; FAST SCANNING; FUNDUS IMAGE; HIGH SPEED LINES; HUMAN RETINA IMAGING; IMAGING SPEED; LARGE FIELD OF VIEWS; MOTION ARTIFACT; RETINAL IMAGING; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHIES; SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY; TIME-PERIODS; TWO-DIRECTIONAL; ULTRA HIGH SPEED;

THREE DIMENSIONAL;

EID: 84863753268     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.002770     Document Type: Article

References (45)

1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography, " Science 254(5035), 1178-1181 (1991).
2. A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser, "Optical coherence tomography-principles and applications, " Rep. Prog. Phys. 66(2), 239-303 (2003).
3. P. H. Tomlins and R. K. Wang, "Theory, developments and applications of optical coherence tomography, " J. Phys. D Appl. Phys. 38(15), 2519-2535 (2005).
4. A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In vivo optical coherence tomography, " Am. J. Ophthalmol. 116(1), 113-114 (1993).
5. C. K. Hitzenberger, P. Trost, P. W. Lo, and Q. Y. Zhou, "Three-dimensional imaging of the human retina by high-speed optical coherence tomography, " Opt. Express 11(21), 2753-2761 (2003).
6. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of intraocular distances by backscattering spectral interferometry, " Opt. Commun. 117(1-2), 43-48 (1995).
7. G. Häusler and M. W. Lindner, "Coherence radar' and 'spectral radar'-new tools for dermatological diagnosis, " J. Biomed. Opt. 3(1), 21-31 (1998).
8. S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source, " Opt. Lett. 22(5), 340-342 (1997).
9. U. Haberland, P. Jansen, V. Blazek, and H. J. Schmitt, "Optical coherence tomography of scattering media using frequency-modulated continuous-wave techniques with tunable near-infrared laser, " Proc. SPIE 2981, 20-28 (1997).
10. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography, " Opt. Lett. 28(21), 2067-2069 (2003).
11. M. Choma, M. Sarunic, C. Yang, and J. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography, " Opt. Express 11(18), 2183-2189 (2003).
12. R. Leitgeb, C. Hitzenberger, and A. Fercher, "Performance of Fourier domain vs. time domain optical coherence tomography, " Opt. Express 11(8), 889-894 (2003).
13. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography, " J. Biomed. Opt. 7(3), 457-463 (2002).
14. B. Cense, N. Nassif, T. Chen, M. Pierce, S.-H. Yun, B. Park, B. Bouma, G. Tearney, and J. de Boer, "Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography, " Opt. Express 12(11), 2435-2447 (2004).
15. D. M. de Bruin, D. L. Burnes, J. Loewenstein, Y. Chen, S. Chang, T. C. Chen, D. D. Esmaili, and J. F. de Boer, "In vivo three-dimensional imaging of neovascular age-related macular degeneration using optical frequency domain imaging at 1050 nm, " Invest. Ophthalmol. Vis. Sci. 49(10), 4545-4552 (2008).
16. E. C. Lee, J. F. de Boer, M. Mujat, H. Lim, and S. H. Yun, "In vivo optical frequency domain imaging of human retina and choroid, " Opt. Express 14(10), 4403-4411 (2006).
17. H. Lim, M. Mujat, C. Kerbage, E. C. Lee, Y. Chen, T. C. Chen, and J. F. de Boer, "High-speed imaging of human retina in vivo with swept-source optical coherence tomography, " Opt. Express 14(26), 12902-12908 (2006).
18. M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, and J. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation, " Opt. Express 12(11), 2404-2422 (2004).
19. R. Leitgeb, W. Drexler, A. Unterhuber, B. Hermann, T. Bajraszewski, T. Le, A. Stingl, and A. Fercher, "Ultrahigh resolution Fourier domain optical coherence tomography, " Opt. Express 12(10), 2156-2165 (2004).
20. V. J. Srinivasan, R. Huber, I. Gorczynska, J. G. Fujimoto, J. Y. Jiang, P. Reisen, and A. E. Cable, "High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm, " Opt. Lett. 32(4), 361-363 (2007).
21. A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser, and R. A. Leitgeb, "Resonant Doppler flow imaging and optical vivisection of retinal blood vessels, " Opt. Express 15(2), 408-422 (2007).
22. L. An and R. K. Wang, "In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography, " Opt. Express 16(15), 11438-11452 (2008).
23. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, "Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging, " Nat. Med. 15(10), 1219-1223 (2009).
24. B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical coherence tomography, " Opt. Express 11(25), 3490-3497 (2003).
25. J. Fingler, R. J. Zawadzki, J. S. Werner, D. Schwartz, and S. E. Fraser, "Volumetric microvascular imaging of human retina using optical coherence tomography with a novel motion contrast technique, " Opt. Express 17(24), 22190-22200 (2009).
26. L. An, H. M. Subhush, D. J. Wilson, and R. K. Wang, "High-resolution wide-field imaging of retinal and choroidal blood perfusion with optical microangiography, " J. Biomed. Opt. 15(2), 026011 (2010).
27. L. Yu and Z. Chen, "Doppler variance imaging for three-dimensional retina and choroid angiography, " J. Biomed. Opt. 15(1), 016029 (2010).
28. M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint spectral and time domain optical coherence tomography, " Opt. Express 16(9), 6008-6025 (2008).
29. R. K. Wang, L. An, S. Saunders, and D. J. Wilson, "Optical microangiography provides depth-resolved images of directional ocular blood perfusion in posterior eye segment, " J. Biomed. Opt. 15(2), 020502 (2010).
30. S. Makita, F. Jaillon, M. Yamanari, M. Miura, and Y. Yasuno, "Comprehensive in vivo micro-vascular imaging of the human eye by dual-beam-scan Doppler optical coherence angiography, " Opt. Express 19(2), 1271-1283 (2011).
31. S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, "Optical coherence angiography, " Opt. Express 14(17), 7821-7840 (2006).
32. S. Zotter, M. Pircher, T. Torzicky, M. Bonesi, E. Götzinger, R. A. Leitgeb, and C. K. Hitzenberger, "Visualization of microvasculature by dual-beam phase-resolved Doppler optical coherence tomography, " Opt. Express 19(2), 1217-1227 (2011).
33. Y. K. Tao, K. M. Kennedy, and J. A. Izatt, "Velocity-resolved 3D retinal microvessel imaging using single-pass flow imaging spectral domain optical coherence tomography, " Opt. Express 17(5), 4177-4188 (2009).
34. B. Potsaid, B. Baumann, D. Huang, S. Barry, A. E. Cable, J. S. Schuman, J. S. Duker, and J. G. Fujimoto, "Ultrahigh speed 1050nm swept source/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second, " Opt. Express 18(19), 20029-20048 (2010).
35. C. M. Eigenwillig, T. Klein, W. Wieser, B. R. Biedermann, and R. Huber, "Wavelength swept amplified spontaneous emission source for high speed retinal optical coherence tomography at 1060 nm, " J. Biophotonics 4(7-8), 522-528 (2011).
36. M. Gora, K. Karnowski, M. Szkulmowski, B. J. Kaluzny, R. Huber, A. Kowalczyk, and M. Wojtkowski, "Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range, " Opt. Express 17(17), 14880-14894 (2009).
37. V. J. Srinivasan, D. C. Adler, Y. Chen, I. Gorczynska, R. Huber, J. S. Duker, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-speed optical coherence tomography for three-dimensional and en face imaging of the retina and optic nerve head, " Invest. Ophthalmol. Vis. Sci. 49(11), 5103-5110 (2008).
38. B. Potsaid, I. Gorczynska, V. J. Srinivasan, Y. L. Chen, J. Jiang, A. Cable, and J. G. Fujimoto, "Ultrahigh speed spectral/Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second, " Opt. Express 16(19), 15149-15169 (2008).
39. D. Y. Kim, J. Fingler, J. S. Werner, D. M. Schwartz, S. E. Fraser, and R. J. Zawadzki, "In vivo volumetric imaging of human retinal circulation with phase-variance optical coherence tomography, " Biomed. Opt. Express 2(6), 1504-1513 (2011).
40. R. K. Wang, L. An, P. Francis, and D. J. Wilson, "Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography, " Opt. Lett. 35(9), 1467-1469 (2010).
41. W. Wieser, B. R. Biedermann, T. Klein, C. M. Eigenwillig, and R. Huber, "Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second, " Opt. Express 18(14), 14685-14704 (2010).
42. T. Klein, W. Wieser, C. M. Eigenwillig, B. R. Biedermann, and R. Huber, "Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser, " Opt. Express 19(4), 3044-3062 (2011).
43. L. An, G. Guan, and R. K. Wang, "High-speed 1310 nm-band spectral domain optical coherence tomography at 184,000 lines per second, " J. Biomed. Opt. 16(6), 060506 (2011).
44. H. C. Hendargo, M. Zhao, N. Shepherd, and J. A. Izatt, "Synthetic wavelength based phase unwrapping in spectral domain optical coherence tomography, " Opt. Express 17(7), 5039-5051 (2009).
45. S. L. Jiao, R. Knighton, X. R. Huang, G. Gregori, and C. A. Puliafito, "Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography, " Opt. Express 13(2), 444-452