Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Soh, Byoung Yul ^a   Song, Hyun Ok ^b   Lee, Yoonji ^c   Lee, Junghyun ^c   Kaewintajuk, Kusuma ^b   Lee, Binna ^b   Choi, Yun Young ^b   Cho, Jeong Hoon ^d   Choi, Sun ^c   Park, Hyun ^b  

^a Seonam University   (South Korea)

^b Wonkwang University School of Medicine   (South Korea)

^c Ewha Womans University   (South Korea)

^d Chosun University   (South Korea)

Author keywords

Anti malarial drug; Calpain; Cysteine protease; Malaria; Monomer; Plasmodium falciparum; Protease inhibitor

Indexed keywords

ASPARAGINE; CALPAIN; CYSTEINE PROTEINASE INHIBITOR; CYSTINE; GELATIN; HISTIDINE; PLASMODIUM FALCIPARUM CALPAIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PURIFICATION; ENZYME SUBSTRATE; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; PROTEIN DOMAIN; PROTEIN EXPRESSION; ZYMOGRAPHY;

AMINO ACID SEQUENCE; ANTIMALARIALS; CALPAIN; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84873190447     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-47     Document Type: Article

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