-
1
-
-
0030755596
-
Psoriasis
-
Stern RS,. Psoriasis. Lancet 1997; 350: 349-53.
-
(1997)
Lancet
, vol.350
, pp. 349-353
-
-
Stern, R.S.1
-
2
-
-
0029887202
-
Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment
-
Koo J,. Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment. Dermatol Clin 1996; 14: 485-96.
-
(1996)
Dermatol Clin
, vol.14
, pp. 485-496
-
-
Koo, J.1
-
3
-
-
0035724176
-
Psoriasis - Epidemiology and clinical spectrum
-
Christophers E,. Psoriasis-epidemiology and clinical spectrum. Clin Exp Dermatol 2001; 26: 314-20.
-
(2001)
Clin Exp Dermatol
, vol.26
, pp. 314-320
-
-
Christophers, E.1
-
4
-
-
31144468296
-
Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2
-
et al.
-
Johansen C, Funding AT, Otkjaer K, et al. Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. J Immunol 2006; 176: 1431-8.
-
(2006)
J Immunol
, vol.176
, pp. 1431-1438
-
-
Johansen, C.1
Funding, A.T.2
Otkjaer, K.3
-
5
-
-
36249006497
-
The activity of caspase-1 is increased in lesional psoriatic epidermis
-
et al.
-
Johansen C, Moeller K, Kragballe K, et al. The activity of caspase-1 is increased in lesional psoriatic epidermis. J Invest Dermatol 2007; 127: 2857-64.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2857-2864
-
-
Johansen, C.1
Moeller, K.2
Kragballe, K.3
-
6
-
-
0041464828
-
Aberrant signalling and transcription factor activation as an explanation for the defective growth control and differentiation of keratinocytes in psoriasis: A hypothesis
-
McKenzie RC, Sabin E,. Aberrant signalling and transcription factor activation as an explanation for the defective growth control and differentiation of keratinocytes in psoriasis: a hypothesis. Exp Dermatol 2003; 12: 337-45.
-
(2003)
Exp Dermatol
, vol.12
, pp. 337-345
-
-
McKenzie, R.C.1
Sabin, E.2
-
7
-
-
1642493842
-
In psoriasis lesional skin the type i interferon signaling pathway is activated, whereas interferon-alpha sensitivity is unaltered
-
et al.
-
Van der Fits L, Van der Wel LI, Laman JD, et al. In psoriasis lesional skin the type I interferon signaling pathway is activated, whereas interferon-alpha sensitivity is unaltered. J Invest Dermatol 2004; 122: 51-60.
-
(2004)
J Invest Dermatol
, vol.122
, pp. 51-60
-
-
Van Der Fits, L.1
Van Der Wel, L.I.2
Laman, J.D.3
-
8
-
-
33644788916
-
Increased sensitivity to interferon-alpha in psoriatic T cells
-
et al.
-
Eriksen KW, Lovato P, Skov L, et al. Increased sensitivity to interferon-alpha in psoriatic T cells. J Invest Dermatol 2005; 125: 936-44.
-
(2005)
J Invest Dermatol
, vol.125
, pp. 936-944
-
-
Eriksen, K.W.1
Lovato, P.2
Skov, L.3
-
9
-
-
79958825496
-
Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways
-
et al.
-
Racz E, Prens EP, Kurek D, et al. Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways. J Invest Dermatol 2011; 131: 1547-58.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1547-1558
-
-
Racz, E.1
Prens, E.P.2
Kurek, D.3
-
10
-
-
80051788025
-
Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation
-
et al.
-
Fridman JS, Scherle PA, Collins R, et al. Preclinical evaluation of local JAK1 and JAK2 inhibition in cutaneous inflammation. J Invest Dermatol 2011; 131: 1838-44.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1838-1844
-
-
Fridman, J.S.1
Scherle, P.A.2
Collins, R.3
-
11
-
-
68149182278
-
JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice
-
et al.
-
Chang BY, Zhao F, He X, et al. JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice. J Immunol 2009; 183: 2183-92.
-
(2009)
J Immunol
, vol.183
, pp. 2183-2192
-
-
Chang, B.Y.1
Zhao, F.2
He, X.3
-
12
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr,. STATs and gene regulation. Science 1997; 277: 1630-5.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, Jr.J.E.1
-
13
-
-
0029149376
-
The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors
-
et al.
-
Sakatsume M, Igarashi K, Winestock KD, et al. The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors. J Biol Chem 1995; 270: 17528-34.
-
(1995)
J Biol Chem
, vol.270
, pp. 17528-17534
-
-
Sakatsume, M.1
Igarashi, K.2
Winestock, K.D.3
-
14
-
-
0028175969
-
Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor
-
et al.
-
Igarashi K, Garotta G, Ozmen L, et al. Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J Biol Chem 1994; 269: 14333-6.
-
(1994)
J Biol Chem
, vol.269
, pp. 14333-14336
-
-
Igarashi, K.1
Garotta, G.2
Ozmen, L.3
-
15
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE Jr, Kerr IM, Stark GR,. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-21.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, Jr.J.E.1
Kerr, I.M.2
Stark, G.R.3
-
16
-
-
0033569905
-
P38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
-
Goh KC, Haque SJ, Williams BR,. p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. EMBO J 1999; 18: 5601-8.
-
(1999)
EMBO J
, vol.18
, pp. 5601-5608
-
-
Goh, K.C.1
Haque, S.J.2
Williams, B.R.3
-
17
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker T, Kovarik P,. Serine phosphorylation of STATs. Oncogene 2000; 19: 2628-37.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
18
-
-
0037177813
-
Protein kinase C-delta (PKC-delta) is activated by type i interferons and mediates phosphorylation of Stat1 on serine 727
-
et al.
-
Uddin S, Sassano A, Deb DK, et al. Protein kinase C-delta (PKC-delta) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J Biol Chem 2002; 277: 14408-16.
-
(2002)
J Biol Chem
, vol.277
, pp. 14408-14416
-
-
Uddin, S.1
Sassano, A.2
Deb, D.K.3
-
19
-
-
78649668321
-
Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFalpha therapy
-
et al.
-
Johansen C, Vinter H, Soegaard-Madsen L, et al. Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFalpha therapy. Br J Dermatol 2010; 163: 1194-204.
-
(2010)
Br J Dermatol
, vol.163
, pp. 1194-1204
-
-
Johansen, C.1
Vinter, H.2
Soegaard-Madsen, L.3
-
20
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z, Wen Z, Darnell JE Jr,. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994; 264: 95-8.
-
(1994)
Science
, vol.264
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell, Jr.J.E.3
-
21
-
-
0028849704
-
Activation of signal transducer and activator of transcription-3 (Stat3) expression by interferon-gamma and interleukin-6 in hepatoma cells
-
et al.
-
Kordula T, Bugno M, Goldstein J, et al. Activation of signal transducer and activator of transcription-3 (Stat3) expression by interferon-gamma and interleukin-6 in hepatoma cells. Biochem Biophys Res Commun 1995; 216: 999-1005.
-
(1995)
Biochem Biophys Res Commun
, vol.216
, pp. 999-1005
-
-
Kordula, T.1
Bugno, M.2
Goldstein, J.3
-
22
-
-
34547108380
-
JAK-STAT signaling: From interferons to cytokines
-
Schindler C, Levy DE, Decker T,. JAK-STAT signaling: from interferons to cytokines. J Biol Chem 2007; 282: 20059-63.
-
(2007)
J Biol Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
23
-
-
50549092820
-
Type i interferon: Potential therapeutic target for psoriasis?
-
et al.
-
Yao Y, Richman L, Morehouse C, et al. Type I interferon: potential therapeutic target for psoriasis? PLoS ONE 2008; 3: e2737.
-
(2008)
PLoS ONE
, vol.3
-
-
Yao, Y.1
Richman, L.2
Morehouse, C.3
-
24
-
-
33749059366
-
TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent
-
Shoenfelt JL, Fenton MJ,. TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent. J Endotoxin Res 2006; 12: 231-40.
-
(2006)
J Endotoxin Res
, vol.12
, pp. 231-240
-
-
Shoenfelt, J.L.1
Fenton, M.J.2
-
25
-
-
13244284850
-
The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin
-
et al.
-
Johansen C, Kragballe K, Westergaard M, et al. The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin. Br J Dermatol 2005; 152: 37-42.
-
(2005)
Br J Dermatol
, vol.152
, pp. 37-42
-
-
Johansen, C.1
Kragballe, K.2
Westergaard, M.3
-
26
-
-
0034928727
-
Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase
-
et al.
-
Rahman A, Anwar KN, Uddin S, et al. Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase. Mol Cell Biol 2001; 21: 5554-65.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5554-5565
-
-
Rahman, A.1
Anwar, K.N.2
Uddin, S.3
-
27
-
-
67649397492
-
CP-690550, a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders
-
West K,. CP-690550, a JAK3 inhibitor as an immunosuppressant for the treatment of rheumatoid arthritis, transplant rejection, psoriasis and other immune-mediated disorders. Curr Opin Investig Drugs 2009; 10: 491-504.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 491-504
-
-
West, K.1
-
28
-
-
77953208379
-
Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis
-
Mesa RA,. Ruxolitinib, a selective JAK1 and JAK2 inhibitor for the treatment of myeloproliferative neoplasms and psoriasis. IDrugs 2010; 13: 394-403.
-
(2010)
IDrugs
, vol.13
, pp. 394-403
-
-
Mesa, R.A.1
-
29
-
-
79954620949
-
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis
-
et al.
-
Stump KL, Lu LD, Dobrzanski P, et al. A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis. Arthritis Res Ther 2011; 13: R68.
-
(2011)
Arthritis Res Ther
, vol.13
-
-
Stump, K.L.1
Lu, L.D.2
Dobrzanski, P.3
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