Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression

Marine Drugs

Volumn 11, Issue 1, 2013, Pages 99-113

  Lee, Hsin Pai ^a,b   Huang, Shi Ying ^a   Lin, Yen You ^a   Wang, Hui Min ^c   Jean, Yen Hsuan ^b   Wu, Shu Fen ^d   Duh, Chang Yih ^a   Wen, Zhi Hong ^a  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

Allodynia; Gout; Inflammation; Lemnalol; Monosodium urate

Indexed keywords

COLCHICINE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; LEMNALOL; NATURAL PRODUCT; PROTEIN C FOS; UNCLASSIFIED DRUG; URATE;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANKLE EDEMA; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CORAL; DRUG EFFICACY; DRUG POTENCY; GOUT; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; KNEE DISEASE; KNEE SWELLING; LEUKOCYTE COUNT; LEUKOCYTE MIGRATION INHIBITION; MALE; MECHANICAL ALLODYNIA; MORPHOMETRICS; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NOCICEPTION; NONHUMAN; PAW EDEMA; PHAGOCYTOSIS; PROTEIN EXPRESSION; RAT; RISK REDUCTION; SYNOVIUM; THERAPY EFFECT;

EID: 84873173679     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md11010099     Document Type: Article

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