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Volumn 10, Issue 1, 2013, Pages 29-33

Alemtuzumab Therapy for Multiple Sclerosis

Author keywords

Alemtuzumab; Antibody; Autoimmunity; Disability; Multiple sclerosis

Indexed keywords

ALEMTUZUMAB; BETA1A INTERFERON; CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISOLONE; RITUXIMAB;

EID: 84873150369     PISSN: 19337213     EISSN: 18787479     Source Type: Journal    
DOI: 10.1007/s13311-012-0159-0     Document Type: Review
Times cited : (60)

References (28)
  • 1
    • 0023911111 scopus 로고
    • Reshaping human antibodies for therapy
    • Riechmann L, et al. Reshaping human antibodies for therapy. Nature 1988; 332: 323-327.
    • (1988) Nature , vol.332 , pp. 323-327
    • Riechmann, L.1
  • 2
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256: 495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 4
    • 0345099473 scopus 로고    scopus 로고
    • Remission induction in Behcet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H
    • Lockwood CM, et al. Remission induction in Behcet's disease following lymphocyte depletion by the anti-CD52 antibody CAMPATH 1-H. Rheumatology (Oxford) 2003; 42: 1539-1544.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 1539-1544
    • Lockwood, C.M.1
  • 5
    • 0034061309 scopus 로고    scopus 로고
    • Campath-1H therapy in refractory ocular inflammatory disease
    • Dick AD, et al. Campath-1H therapy in refractory ocular inflammatory disease. Br J Ophthalmol 2000; 84: 107-109.
    • (2000) Br J Ophthalmol , vol.84 , pp. 107-109
    • Dick, A.D.1
  • 6
    • 0028787543 scopus 로고
    • Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H
    • Isaacs JD, et al. Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H. Br J Ophthalmol 1995; 79: 1054-1055.
    • (1995) Br J Ophthalmol , vol.79 , pp. 1054-1055
    • Isaacs, J.D.1
  • 7
    • 0029934535 scopus 로고    scopus 로고
    • Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H
    • Isaacs JD, et al. Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H. J Rheumatol 1996; 23: 1103-1106.
    • (1996) J Rheumatol , vol.23 , pp. 1103-1106
    • Isaacs, J.D.1
  • 8
    • 0029875268 scopus 로고    scopus 로고
    • CAMPATH-1H in rheumatoid arthritis - an intravenous dose-ranging study
    • Isaacs JD, et al. CAMPATH-1H in rheumatoid arthritis - an intravenous dose-ranging study. Br J Rheumatol 1996; 35: 231-240.
    • (1996) Br J Rheumatol , vol.35 , pp. 231-240
    • Isaacs, J.D.1
  • 9
    • 0028807213 scopus 로고
    • Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody
    • Newman DK, et al. Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody. CAMPATH-1H. Eye (Lond) 1995; 9(pt 5): 564-569.
    • (1995) CAMPATH-1H Eye (Lond) , vol.9 , Issue.Pt 5 , pp. 564-569
    • Newman, D.K.1
  • 10
    • 0034765991 scopus 로고    scopus 로고
    • The CD52 antigen and development of the CAMPATH antibodies
    • Hale G. The CD52 antigen and development of the CAMPATH antibodies. Cytotherapy 2001; 3: 137-143.
    • (2001) Cytotherapy , vol.3 , pp. 137-143
    • Hale, G.1
  • 11
    • 0027194472 scopus 로고
    • Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis
    • Xia MQ, et al. Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis. Biochem J 1993; 293(pt 3): 633-640.
    • (1993) Biochem J , vol.293 , Issue.Pt 3 , pp. 633-640
    • Xia, M.Q.1
  • 12
    • 0025878925 scopus 로고
    • Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone
    • Xia MQ, et al. Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone. Eur J Immunol 1991; 21: 1677-1684.
    • (1991) Eur J Immunol , vol.21 , pp. 1677-1684
    • Xia, M.Q.1
  • 13
    • 69949120991 scopus 로고    scopus 로고
    • Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model
    • Hu Y, et al. Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model. Immunology 2009; 260-270.
    • (2009) Immunology , pp. 260-270
    • Hu, Y.1
  • 14
    • 0030453977 scopus 로고    scopus 로고
    • Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells
    • Wing MG, et al. Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells. J Clin Invest 1996; 98: 2819-2826.
    • (1996) J Clin Invest , vol.98 , pp. 2819-2826
    • Wing, M.G.1
  • 15
    • 0029869119 scopus 로고    scopus 로고
    • Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis
    • Moreau T, et al. Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis. Brain 1996; 119(pt 1): 225-237.
    • (1996) Brain , vol.119 , Issue.Pt 1 , pp. 225-237
    • Moreau, T.1
  • 16
    • 84857055778 scopus 로고    scopus 로고
    • Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis
    • Hill-Cawthorne GA, et al. Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis. J Neurol Neurosurg Psychiatry 2012; 83: 298-304.
    • (2012) J Neurol Neurosurg Psychiatry , vol.83 , pp. 298-304
    • Hill-Cawthorne, G.A.1
  • 17
    • 27944439639 scopus 로고    scopus 로고
    • Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
    • Cox AL, et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005; 35: 3332-3342.
    • (2005) Eur J Immunol , vol.35 , pp. 3332-3342
    • Cox, A.L.1
  • 18
    • 77249114139 scopus 로고    scopus 로고
    • B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) Treatment of Multiple Sclerosis
    • Thompson SA, et al. B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) Treatment of Multiple Sclerosis. J Clin Immunol 2009; 99-105.
    • (2009) J Clin Immunol , pp. 99-105
    • Thompson, S.A.1
  • 19
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple-sclerosis - an Expanded Disability Status Scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple-sclerosis - an Expanded Disability Status Scale (EDSS). Neurology 1983; 33: 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 20
    • 0032882173 scopus 로고    scopus 로고
    • Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
    • Coles AJ, et al. Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis. Ann Neurol 1999; 46: 296-304.
    • (1999) Ann Neurol , vol.46 , pp. 296-304
    • Coles, A.J.1
  • 21
    • 31544467633 scopus 로고    scopus 로고
    • The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy
    • Coles AJ, et al. The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy. J Neurol 2006; 253: 98-108.
    • (2006) J Neurol , vol.253 , pp. 98-108
    • Coles, A.J.1
  • 22
    • 84860780657 scopus 로고    scopus 로고
    • Alemtuzumab more effective than interferon beta-1a at 5-year follow-up of CAMMS223 Clinical Trial
    • Coles AJ, et al. Alemtuzumab more effective than interferon beta-1a at 5-year follow-up of CAMMS223 Clinical Trial. Neurology 2012; 1069-78.
    • (2012) Neurology , pp. 1069-1078
    • Coles, A.J.1
  • 23
    • 79951720337 scopus 로고    scopus 로고
    • Prevalence of incidental thyroid cancer and its ultrasonographic features in subcentimeter thyroid nodules of patients with hyperthyroidism
    • Berker D, et al. Prevalence of incidental thyroid cancer and its ultrasonographic features in subcentimeter thyroid nodules of patients with hyperthyroidism. Endocrine 2011; 39: 13-20.
    • (2011) Endocrine , vol.39 , pp. 13-20
    • Berker, D.1
  • 24
    • 77956209762 scopus 로고    scopus 로고
    • A novel strategy to reduce the immunogenicity of biological therapies
    • Somerfield J, et al. A novel strategy to reduce the immunogenicity of biological therapies. J Immunol 2010; 185: 763-768.
    • (2010) J Immunol , vol.185 , pp. 763-768
    • Somerfield, J.1
  • 25
    • 49449108196 scopus 로고    scopus 로고
    • Anti-glomerular basement membrane disease after alemtuzumab
    • Clatworthy MR, Wallin EF, Jayne DR. Anti-glomerular basement membrane disease after alemtuzumab. N Engl J Med 2008; 359: 768-769.
    • (2008) N Engl J Med , vol.359 , pp. 768-769
    • Clatworthy, M.R.1    Wallin, E.F.2    Jayne, D.R.3
  • 26
    • 0035691941 scopus 로고    scopus 로고
    • Relapse of Graves' disease after successful allogeneic bone marrow transplantation
    • Hsiao LT, et al. Relapse of Graves' disease after successful allogeneic bone marrow transplantation. Bone Marrow Transplant 2001; 28: 1151-1153.
    • (2001) Bone Marrow Transplant , vol.28 , pp. 1151-1153
    • Hsiao, L.T.1
  • 27
    • 0032512301 scopus 로고    scopus 로고
    • Delayed occurrence of Graves' disease after immune restoration with HAART
    • Gilquin J, et al. Delayed occurrence of Graves' disease after immune restoration with HAART. Lancet 1998; 352: 1907-1908.
    • (1998) Lancet , vol.352 , pp. 1907-1908
    • Gilquin, J.1
  • 28
    • 68849084141 scopus 로고    scopus 로고
    • IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)
    • Jones JL, et al. IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H). J Clin Invest 2009; 119: 2052-2061.
    • (2009) J Clin Invest , vol.119 , pp. 2052-2061
    • Jones, J.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.