Transendocardial delivery of HGF via microbubbles and ultrasound to treat acute myocardial infarction

Current Gene Therapy

Volumn 13, Issue 1, 2013, Pages 31-38

  Yuan, Qiao Ying ^a   Huang, Jing ^b   Li, Xue Jun ^a   Li, Xing Sheng ^b   Si, Liang Yi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Intracardiac ultrasound; Microbubble; Myocardial infarction; Transendocardial delivery

Indexed keywords

COLLAGEN; CONTRAST MEDIUM; SCATTER FACTOR;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CAPILLARY DENSITY; CONTROLLED STUDY; DOG; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HEART LEFT VENTRICLE MASS; HISTOPATHOLOGY; IN VIVO GENE TRANSFER; MALE; MICROBUBBLE; NONHUMAN; ULTRASOUND;

ANIMALS; DISEASE MODELS, ANIMAL; DOGS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HEART VENTRICLES; HEPATOCYTE GROWTH FACTOR; HUMANS; MICROBUBBLES; MYOCARDIAL INFARCTION; NEOVASCULARIZATION, PHYSIOLOGIC; ULTRASONICS;

EID: 84873150139     PISSN: 15665232     EISSN: 18755631     Source Type: Journal    
DOI: 10.2174/156652313804806598     Document Type: Article

References (27)

1. Roger VL. Epidemiology of myocardial infarction. Med Clin North Am 2007; 91: 537-52.
2. Ueda H, Nakamura T, Matsumoto K, Sawa Y, Matsuda H, Nakamura T. A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc Res 2001; 51: 41-50.
3. Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H, Nakamura T. Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest 2000; 106: 1511-9.
4. Isao K, Koji O, Akira O, Hiroto T. Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction. J Am Coll Cardiol 2004; 44: 644-53.
5. French BA, Mazur W, Geske RS. Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 1994; 90: 2414-24.
6. Verma IM, Somia N. Gene therapy: promises, problems and prospects. Nature 1997; 389: 239-42.
7. Sasano T, Kikuchi K, McDonald AD, Lai S, Donahue JK. Targeted high-efficiency, homogeneous myocardial gene transfer. J Mol Cell Cardiol 2007; 42: 954-61.
8. Weig H, Laugwitz KL, Moretti A, et al. Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors in vivo by ultrasound-guided injection or transcoronary delivery. Circulation 2000; 101: 1578-85.
9. Kikuch K, McDonald AD, Sasano T, Donahue JK. Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. Circulation 2005; 111: 264-70.
10. R. Hajjar, U. Schmidt, T. Matsui, L. Guerrero, K. Lee and J. Gwathmey et al., Modulation of ventricular function through gene transfer in vivo, Proc Natl Acad Sci U S A 1998; 95: 5251-6.
11. Davidson M, Jones J, Emani S, et al. Cardiac gene delivery with cardiopulmonary bypass. Circulation 2001; 104: 131-3.
12. Vale PR, Losordo DW, Milliken CE, et al. Randomized, singleblind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia. Circulation 2001; 103: 2138-43.
13. Markkanen JE, Rissanen TT, Kivelä A, Ylä-Herttuala S. Growth factor-induced therapeutic angiogenesis and arteriogenesis in the heart-gene therapy. Cardiovasc Res 2005; 65: 656-64.
14. Krombach GA, Pfeffer JG, Kinzel S, Katoh M, Günther R, Buecker A. MR-guided percutaneous intramyocardial injection with an MRcompatible catheter: feasibility and changes in T1 values after injection of extracellular contrast medium in pigs. Radiology 2005; 235: 487-94.
15. Yoshiaki T, Junya A, Hiromi R, Ryuichi M. Plasmid DNA-based gene transfer with ultrasound and microbubbles. Curr Gene Ther 2011; 11(6): 485-90.
16. Guo DP, Li XY, Sun P, et al. Ultrasound-targeted microbubble destruction improves the low density lipoprotein receptor gene ex pression in HepG2 cells. Biochem Biophys Res Comm 2006; 343: 470-4.
17. Li XS, Wang ZG, Ran HT, et al. Experimental research on therapeutic angiogenesis induced by hepatocyte growth factor directed by ultrasound-targeted microbubble destruction in rats. J Ultrasound Med 2008; 27: 453-60.
18. Bodh IJ, Vijayan M, Dinender K, Halliday I. Vascular remodeling during healing after myocardial infarction in the dog model: effects of reperfusion, amlodipine and enalapril. J Am Coll Cardiol 2002; 39: 1538-45.
19. Li TL, Tachibana K, Motomu K, Masahide K. Gene transfer with echo-enhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice-initial results. Radiology 2003; 229: 423-8.
20. Junqueira LCU, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue section. Histochem J 1979; 11: 445-7.
21. Woessner JF. The determination of hydroxyproline in tissue and protein samples containing small proportions of this amino acid. Arch Biochem Biophys 1961; 93: 440-7.
22. Ren JF, Marchlinski F. Intracardiac ultrasound catheter imaging for electrophysiologic substrate of AV nodal reentrant tachycardia: anatomic versus electrophysiologic evidence. J Cardiovasc Electrophysiol 2004; 15: 274-5.
23. Taniyama Y, Tachibana K, Hiraoka K, et al. Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther 2002; 9: 372-80.
24. Beeri R, Guerrero JL, Supple G, Sullivan S, Levine RA, Hajjar RJ. New efficient catheter-based system for myocardial gene delivery. Circulation 2002; 106: 1756-9.
25. Chappell JC, Song J, Klibanov AL, Price RJ. Ultrasonic microbubble destruction stimulates therapeutic arteriogenesis via the CD18-dependent recruitment of bone marrow-derived cells. Arterioscler Thromb Vasc Biol 2008; 28: 1117-22.
26. Yuan QY, Huang J, Chu BC, Li XS, Si LY. A visible, targeted high-efficiency gene delivery and transfection strategy. BMC Biotechnol, 2011; 11: 56.
27. Taniyama Y, Morishita R, Aoki M, Hiraoka K, Yamasaki K, Hashiya N, et al. Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy. Hypertension 2002; 40: 47-53.