Involvement of Nrf2 activation in the upregulation of S100A9 by exposure to inorganic arsenite

International Journal of Molecular Medicine

Volumn 31, Issue 1, 2013, Pages 259-264

  Sumi, Daigo ^a   Shimizu, Yuri ^a   Himeno, Seiichiro ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Arsenic; NF E2 related factor 2; S100A8; S100A9

Indexed keywords

ARSENITE SODIUM; CALGRANULIN A; CALGRANULIN B; COMPLEMENTARY DNA; GENOMIC DNA; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARSENIC POISONING; ARTICLE; CELL ACTIVATION; CELL CULTURE; CYTOTOXICITY; DELETION MUTANT; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; LONG TERM EXPOSURE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; TRANSIENT TRANSFECTION; UPREGULATION; WESTERN BLOTTING;

ARSENITES; CALGRANULIN A; CALGRANULIN B; CELL LINE, TUMOR; EPITHELIAL CELLS; HUMANS; KERATINOCYTES; NF-E2-RELATED FACTOR 2; PROMOTER REGIONS, GENETIC; SODIUM COMPOUNDS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION; UROTHELIUM;

EID: 84873139614     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.1185     Document Type: Article

References (31)

1. Engel RR, Hopenhayn-Rich C, Receveur O and Smith AH: Vascular effects of chronic arsenic exposure: a review. Epidemiol Rev 16: 184-209, 1994.
2. Tseng WP, Chu HM, How SW, Fong JM, Lin CS and Yeh S: Prevalence of skin cancer in an endemic area of chronic arsenicism in Taiwan. J Natl Cancer Inst 40: 453-463, 1968.
3. Kozul CD, Hampton TH, Davey JC, et al: Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Environ Health Perspect 117: 1108-1115, 2009.
4. + cell apoptosis in patients with arsenic-induced Bowen's disease. Carcinogenesis 30: 1064-1072, 2009.
5. Banerjee N, Banerjee S, Sen R, et al: Chronic arsenic exposure impairs macrophage functions in the exposed individuals. J Clin Immunol 29: 582-594, 2009.
6. Shimizu Y, Fujishiro H, Matsumoto K, Sumi D, Satoh M and Himeno S: Chronic exposure to arsenite induces S100A8 and S100A9 expression in rat RBL-2H3 mast cells. J Toxicol Sci 36: 135-139, 2011.
7. Ehrchen JM, Sunderkotter C, Foell D, Vogl T and Roth J: The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer. J Leukoc Biol 86: 557-566, 2009.
8. Nacken W, Roth J, Sorg C and Kerkhoff C: S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity. Microsc Res Tech 60: 569-580, 2003.
9. phox and Rac-2. FASEB J 19: 467-469, 2005.
10. Kerkhoff C, Sorg C, Tandon NN and Nacken W: Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells. Biochemistry 40: 241-248, 2001.
11. + T cells. Nat Med 16: 713-717, 2010.
12. Itoh K, Tong KI and Yamamoto M: Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic Biol Med 36: 1208-1213, 2004.
13. Aono J, Yanagawa T, Itoh K, et al: Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts. Biochem Biophys Res Commun 305: 271-277, 2003.
14. Kumagai Y and Sumi D: Arsenic: signal transduction, transcription factor, and biotransformation involved in cellular response and toxicity. Annu Rev Pharmacol Toxicol 47: 243-262, 2007.
15. Fusenig NE and Boukamp P: Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes. Mol Carcinog 23: 144-158, 1998.
16. Rossi MR, Masters JR, Park S, et al: The immortalized UROtsa cell line as a potential cell culture model of human urothelium. Environ Health Perspect 109: 801-808, 2001.
17. Cheng P, Corzo CA, Luetteke N, et al: Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med 205: 2235-2249, 2008.
18. + human monocytes. Int Immunol 12: 1593-1604, 2000.
19. Kerkhoff C, Hofmann HA, Vormoor J, et al: Binding of two nuclear complexes to a novel regulatory element within the human S100A9 promoter drives the S100A9 gene expression. J Biol Chem 277: 41879-41887, 2002.
20. Melkonyan H, Hofmann HA, Nacken W, Sorg C and Klempt M: The gene encoding the myeloid-related protein 14 (MRP14), a calcium-binding protein expressed in granulocytes and monocytes, contains a potent enhancer element in the first intron. J Biol Chem 273: 27026-27032, 1998.
21. Pi J, Qu W, Reece JM, Kumagai Y and Waalkes MP: Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide. Exp Cell Res 290: 234-245, 2003.
22. Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF and Zhang DD: Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicol Appl Pharmacol 230: 383-389, 2008.
23. Wang XJ, Sun Z, Chen W, Eblin KE, Gandolfi JA and Zhang DD: Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicol Appl Pharmacol 225: 206-213, 2007.
24. Lin L, Stringfield TM, Shi X and Chen Y: Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein. Biochem J 392: 93-102, 2005.
25. Barchowsky A, Dudek EJ, Treadwell MD and Wetterhahn KE: Arsenic induces oxidant stress and NF-kappa B activation in cultured aortic endothelial cells. Free Radic Biol Med 21: 783-790, 1996.
26. Barchowsky A, Roussel RR, Klei LR, et al: Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways. Toxicol Appl Pharmacol 159: 65-75, 1999.
27. Xu K, Yen T and Geczy CL: IL-10 upregulates macrophage expression of the S100 protein S100A8. J Immunol 166: 6358-6366, 2001.
28. Kuwayama A, Kuruto R, Horie N, Takeishi K and Nozawa R: Appearance of nuclear factors that interact with genes for myeloid calcium binding proteins (MRP-8 and MRP-14) in differentiated HL-60 cells. Blood 81: 3116-3121, 1993.
29. Shen SC, Yang LY, Lin HY, Wu CY, Su TH and Chen YC: Reactive oxygen species-dependent HSP90 protein cleavage participates in arsenical As(+3)- and MMA(+3)-induced apoptosis through inhibition of telomerase activity via JNK activation. Toxicol Appl Pharmacol 229: 239-251, 2008.
30. Smith KR, Klei LR and Barchowsky A: Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells. Am J Physiol Lung Cell Mol Physiol 280: L442-L449, 2001.
31. Benedyk M, Sopalla C, Nacken W, et al: HaCaT keratinocytes overexpressing the S100 proteins S100A8 and S100A9 show increased NADPH oxidase and NF-kappaB activities. J Invest Dermatol 127: 2001-2011, 2007.