메뉴 건너뛰기




Volumn 56, Issue 1, 2013, Pages 72-80

Thrombomodulin, A novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification

Author keywords

Apoptosis; Calcification; EGF receptor; ERK; Thrombomodulin

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH ARREST SPECIFIC PROTEIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATE; RECOMBINANT EPIDERMAL GROWTH FACTOR; SMALL INTERFERING RNA; THROMBOMODULIN;

EID: 84873117942     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.12.013     Document Type: Article
Times cited : (14)

References (33)
  • 1
    • 77956058459 scopus 로고    scopus 로고
    • Regulatory mechanisms in vascular calcification
    • Sage A.P., Tintut Y., Demer L.L. Regulatory mechanisms in vascular calcification. Nat Rev Cardiol 2010, 7:528-536.
    • (2010) Nat Rev Cardiol , vol.7 , pp. 528-536
    • Sage, A.P.1    Tintut, Y.2    Demer, L.L.3
  • 2
    • 33750904801 scopus 로고    scopus 로고
    • Vascular calcification: pathobiological mechanisms and clinical implications
    • Johnson R.C., Leopold J.A., Loscalzo J. Vascular calcification: pathobiological mechanisms and clinical implications. Circ Res 2006, 99:1044-1059.
    • (2006) Circ Res , vol.99 , pp. 1044-1059
    • Johnson, R.C.1    Leopold, J.A.2    Loscalzo, J.3
  • 3
    • 9544249488 scopus 로고    scopus 로고
    • Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group
    • Wexler L., Brundage B., Crouse J., Detrano R., Fuster V., Maddahi J., et al. Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group. Circulation 1996, 94:1175-1192.
    • (1996) Circulation , vol.94 , pp. 1175-1192
    • Wexler, L.1    Brundage, B.2    Crouse, J.3    Detrano, R.4    Fuster, V.5    Maddahi, J.6
  • 6
    • 0031674015 scopus 로고    scopus 로고
    • Expression of thrombomodulin in atherosclerotic lesions and mitogenic activity of recombinant thrombomodulin in vascular smooth muscle cells
    • Tohda G., Oida K., Okada Y., Kosaka S., Okada E., Takahashi S., et al. Expression of thrombomodulin in atherosclerotic lesions and mitogenic activity of recombinant thrombomodulin in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1998, 18:1861-1869.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1861-1869
    • Tohda, G.1    Oida, K.2    Okada, Y.3    Kosaka, S.4    Okada, E.5    Takahashi, S.6
  • 7
    • 0344443722 scopus 로고    scopus 로고
    • Thrombomodulin-mediated cell adhesion: involvement of its lectin-like domain
    • Huang H.C., Shi G.Y., Jiang S.J., Shi C.S., Wu C.M., Yang H.Y., et al. Thrombomodulin-mediated cell adhesion: involvement of its lectin-like domain. J Biol Chem 2003, 278:46750-46759.
    • (2003) J Biol Chem , vol.278 , pp. 46750-46759
    • Huang, H.C.1    Shi, G.Y.2    Jiang, S.J.3    Shi, C.S.4    Wu, C.M.5    Yang, H.Y.6
  • 8
    • 53449087278 scopus 로고    scopus 로고
    • Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes
    • Ito T., Kawahara K., Okamoto K., Yamada S., Yasuda M., Imaizumi H., et al. Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes. Arterioscler Thromb Vasc Biol 2008, 28:1825-1830.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1825-1830
    • Ito, T.1    Kawahara, K.2    Okamoto, K.3    Yamada, S.4    Yasuda, M.5    Imaizumi, H.6
  • 9
    • 0023374585 scopus 로고
    • Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation
    • Suzuki K., Kusumoto H., Deyashiki Y., Nishioka J., Maruyama I., Zushi M., et al. Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation. EMBO J 1987, 6:1891-1897.
    • (1987) EMBO J , vol.6 , pp. 1891-1897
    • Suzuki, K.1    Kusumoto, H.2    Deyashiki, Y.3    Nishioka, J.4    Maruyama, I.5    Zushi, M.6
  • 10
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon C.T. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J Biol Chem 1989, 264:4743-4746.
    • (1989) J Biol Chem , vol.264 , pp. 4743-4746
    • Esmon, C.T.1
  • 11
    • 0023190511 scopus 로고
    • Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene
    • Wen D., Dittman W.A., Ye R.D., Deaven L.L., Majerus P.W., Sadler J.E. Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene. Biochemistry 1987, 26:4350-4357.
    • (1987) Biochemistry , vol.26 , pp. 4350-4357
    • Wen, D.1    Dittman, W.A.2    Ye, R.D.3    Deaven, L.L.4    Majerus, P.W.5    Sadler, J.E.6
  • 12
    • 0035853404 scopus 로고    scopus 로고
    • Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells
    • Olivot J.M., Estebanell E., Lafay M., Brohard B., Aiach M., Rendu F. Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells. Circ Res 2001, 88:681-687.
    • (2001) Circ Res , vol.88 , pp. 681-687
    • Olivot, J.M.1    Estebanell, E.2    Lafay, M.3    Brohard, B.4    Aiach, M.5    Rendu, F.6
  • 14
    • 33847375078 scopus 로고    scopus 로고
    • Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development
    • Ge C., Xiao G., Jiang D., Franceschi R.T. Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J Cell Biol 2007, 176:709-718.
    • (2007) J Cell Biol , vol.176 , pp. 709-718
    • Ge, C.1    Xiao, G.2    Jiang, D.3    Franceschi, R.T.4
  • 15
    • 0035958030 scopus 로고    scopus 로고
    • Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells
    • Lai C.F., Chaudhary L., Fausto A., Halstead L.R., Ory D.S., Avioli L.V., et al. Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem 2001, 276:14443-14450.
    • (2001) J Biol Chem , vol.276 , pp. 14443-14450
    • Lai, C.F.1    Chaudhary, L.2    Fausto, A.3    Halstead, L.R.4    Ory, D.S.5    Avioli, L.V.6
  • 16
    • 33751165741 scopus 로고    scopus 로고
    • Fibronectin enhances in vitro vascular calcification by promoting osteoblatic differentiation of vascular smooth muscle cells via ERK pathway
    • Ding H.T., Wang C.G., Zhang T.L., Wang K. Fibronectin enhances in vitro vascular calcification by promoting osteoblatic differentiation of vascular smooth muscle cells via ERK pathway. J Cell Biochem 2006, 99:1343-1352.
    • (2006) J Cell Biochem , vol.99 , pp. 1343-1352
    • Ding, H.T.1    Wang, C.G.2    Zhang, T.L.3    Wang, K.4
  • 17
    • 64249157371 scopus 로고    scopus 로고
    • Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries
    • Speer M.Y., Yang H.Y., Brabb T., Leaf E., Look A., Lin W.L., et al. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circ Res 2009, 104:733-741.
    • (2009) Circ Res , vol.104 , pp. 733-741
    • Speer, M.Y.1    Yang, H.Y.2    Brabb, T.3    Leaf, E.4    Look, A.5    Lin, W.L.6
  • 18
    • 33646799150 scopus 로고    scopus 로고
    • Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway
    • Son B.K., Kozaki K., Iijima K., Eto M., Kojima T., Ota H., et al. Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway. Circ Res 2006, 98:1024-1031.
    • (2006) Circ Res , vol.98 , pp. 1024-1031
    • Son, B.K.1    Kozaki, K.2    Iijima, K.3    Eto, M.4    Kojima, T.5    Ota, H.6
  • 19
    • 33846103421 scopus 로고    scopus 로고
    • Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells
    • Son B.K., Kozaki K., Iijima K., Eto M., Nakano T., Akishita M., et al. Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. Eur J Pharmacol 2007, 556:1-8.
    • (2007) Eur J Pharmacol , vol.556 , pp. 1-8
    • Son, B.K.1    Kozaki, K.2    Iijima, K.3    Eto, M.4    Nakano, T.5    Akishita, M.6
  • 20
    • 0029050715 scopus 로고
    • The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells
    • Hamada H., Ishii H., Sakyo K., Horie S., Nishiki K., Kazama M. The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells. Blood 1995, 86:225-233.
    • (1995) Blood , vol.86 , pp. 225-233
    • Hamada, H.1    Ishii, H.2    Sakyo, K.3    Horie, S.4    Nishiki, K.5    Kazama, M.6
  • 21
    • 3042643036 scopus 로고    scopus 로고
    • Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells
    • Watanabe T., Akishita M., Nakaoka T., He H., Miyahara Y., Yamashita N., et al. Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells. Life Sci 2004, 75:1219-1229.
    • (2004) Life Sci , vol.75 , pp. 1219-1229
    • Watanabe, T.1    Akishita, M.2    Nakaoka, T.3    He, H.4    Miyahara, Y.5    Yamashita, N.6
  • 22
    • 0022449729 scopus 로고
    • Animal model of adenine-induced chronic renal failure in rats
    • Yokozawa T., Zheng P.D., Oura H., Koizumi F. Animal model of adenine-induced chronic renal failure in rats. Nephron 1986, 44:230-234.
    • (1986) Nephron , vol.44 , pp. 230-234
    • Yokozawa, T.1    Zheng, P.D.2    Oura, H.3    Koizumi, F.4
  • 23
    • 55449101447 scopus 로고    scopus 로고
    • Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis
    • Shroff R.C., McNair R., Figg N., Skepper J.N., Schurgers L., Gupta A., et al. Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis. Circulation 2008, 118:1748-1757.
    • (2008) Circulation , vol.118 , pp. 1748-1757
    • Shroff, R.C.1    McNair, R.2    Figg, N.3    Skepper, J.N.4    Schurgers, L.5    Gupta, A.6
  • 24
    • 81755174888 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: inhibition by salvianolic acid B from Salvia miltiorrhiza
    • Wang Y., Xu F., Chen J., Shen X., Deng Y., Xu L., et al. Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: inhibition by salvianolic acid B from Salvia miltiorrhiza. Phytomedicine 2011, 19:13-19.
    • (2011) Phytomedicine , vol.19 , pp. 13-19
    • Wang, Y.1    Xu, F.2    Chen, J.3    Shen, X.4    Deng, Y.5    Xu, L.6
  • 25
    • 41549125017 scopus 로고    scopus 로고
    • Adiponectin antagonizes stimulatory effect of TNFalpha on vascular smooth muscle cell calcification: regulation of Gas6-mediated survival pathway by AMP-activated protein kinase
    • Son B.K., Akishita M., Iijima K., Kozaki K., Maemura K., Eto M., et al. Adiponectin antagonizes stimulatory effect of TNFalpha on vascular smooth muscle cell calcification: regulation of Gas6-mediated survival pathway by AMP-activated protein kinase. Endocrinology 2008, 149:1646-1653.
    • (2008) Endocrinology , vol.149 , pp. 1646-1653
    • Son, B.K.1    Akishita, M.2    Iijima, K.3    Kozaki, K.4    Maemura, K.5    Eto, M.6
  • 26
    • 0031154408 scopus 로고    scopus 로고
    • A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality
    • Solorzano C.C., Ksontini R., Pruitt J.H., Auffenberg T., Tannahill C., Galardy R.E., et al. A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality. Shock 1997, 7:427-431.
    • (1997) Shock , vol.7 , pp. 427-431
    • Solorzano, C.C.1    Ksontini, R.2    Pruitt, J.H.3    Auffenberg, T.4    Tannahill, C.5    Galardy, R.E.6
  • 27
    • 84872086903 scopus 로고    scopus 로고
    • Matrix metalloproteinase-1 mediated upregulation of vascular endothelial growth factor-2 in endothelial cells
    • Nov 15
    • Mazor R., Alsaigh T., Shaked H., Altshuler A., Pocock E.S., Kistler E.B., et al. Matrix metalloproteinase-1 mediated upregulation of vascular endothelial growth factor-2 in endothelial cells. J Biol Chem Nov 15 2012.
    • (2012) J Biol Chem
    • Mazor, R.1    Alsaigh, T.2    Shaked, H.3    Altshuler, A.4    Pocock, E.S.5    Kistler, E.B.6
  • 28
    • 84865496914 scopus 로고    scopus 로고
    • Thrombomodulin protects endothelial cells from a calcineurin inhibitor-induced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling
    • Ikezoe T., Yang J., Nishioka C., Honda G., Furihata M., Yokoyama A. Thrombomodulin protects endothelial cells from a calcineurin inhibitor-induced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling. Arterioscler Thromb Vasc Biol 2012, 32:2259-2270.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2259-2270
    • Ikezoe, T.1    Yang, J.2    Nishioka, C.3    Honda, G.4    Furihata, M.5    Yokoyama, A.6
  • 29
    • 67651160384 scopus 로고    scopus 로고
    • Advanced oxidation protein products induce vascular calcification by promoting osteoblastic trans-differentiation of smooth muscle cells via oxidative stress and ERK pathway
    • You H., Yang H., Zhu Q., Li M., Xue J., Gu Y., et al. Advanced oxidation protein products induce vascular calcification by promoting osteoblastic trans-differentiation of smooth muscle cells via oxidative stress and ERK pathway. Ren Fail 2009, 31:313-319.
    • (2009) Ren Fail , vol.31 , pp. 313-319
    • You, H.1    Yang, H.2    Zhu, Q.3    Li, M.4    Xue, J.5    Gu, Y.6
  • 30
    • 77950187706 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells
    • Nakahara T., Sato H., Shimizu T., Tanaka T., Matsui H., Kawai-Kowase K., et al. Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells. Biochem Biophys Res Commun 2010, 394:243-248.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 243-248
    • Nakahara, T.1    Sato, H.2    Shimizu, T.3    Tanaka, T.4    Matsui, H.5    Kawai-Kowase, K.6
  • 31
    • 70450230468 scopus 로고    scopus 로고
    • Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor
    • Ge C., Xiao G., Jiang D., Yang Q., Hatch N.E., Roca H., et al. Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor. J Biol Chem 2009, 284:32533-32543.
    • (2009) J Biol Chem , vol.284 , pp. 32533-32543
    • Ge, C.1    Xiao, G.2    Jiang, D.3    Yang, Q.4    Hatch, N.E.5    Roca, H.6
  • 32
    • 84859435053 scopus 로고    scopus 로고
    • Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies
    • Tan F., Shen X., Wang D., Xie G., Zhang X., Ding L., et al. Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies. Lung Cancer 2012, 76:177-182.
    • (2012) Lung Cancer , vol.76 , pp. 177-182
    • Tan, F.1    Shen, X.2    Wang, D.3    Xie, G.4    Zhang, X.5    Ding, L.6
  • 33
    • 79954579275 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism
    • Habashi J.P., Doyle J.J., Holm T.M., Aziz H., Schoenhoff F., Bedja D., et al. Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. Science 2011, 332:361-365.
    • (2011) Science , vol.332 , pp. 361-365
    • Habashi, J.P.1    Doyle, J.J.2    Holm, T.M.3    Aziz, H.4    Schoenhoff, F.5    Bedja, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.