Obesity is associated with worse oncological outcomes in patients treated with radical cystectomy

BJU International

Volumn 111, Issue 2, 2013, Pages 249-255

  Chromecki, Thomas F ^a,b   Cha, Eugene K ^a   Fajkovic, Harun ^a,c   Rink, Michael ^a,d   Ehdaie, Behfar ^a   Svatek, Robert S ^e   Karakiewicz, Pierre I ^f   Lotan, Yair ^g   Tilki, Derya ^h   Bastian, Patrick J ^h   Daneshmand, Siamak ⁱ   Kassouf, Wassim ^j   Durand, Matthieu ^a   Novara, Giacomo ^k   Fritsche, Hans Martin ^l   Burger, Maximilian ^l   Izawa, Jonathan I ^m   Brisuda, Antonin ⁿ   Babjuk, Marek ⁿ   Pummer, Karl ^b   Shariat, Shahrokh F ^a   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c Landeskrankenhaus St Poelten ^*  (Austria)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^f UNIVERSITÉ DE MONTRÉAL   (Canada)

^g UNIVERSITY OF TEXAS AT DALLAS   (United States)

^h LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

ⁱ UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^j MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^k UNIVERSITY OF PADOVA   (Italy)

^l UNIVERSITY OF REGENSBURG   (Germany)

^m UNIVERSITY OF WESTERN ONTARIO   (Canada)

ⁿ CHARLES UNIVERSITY   (Czech Republic)

more..

Author keywords

bladder cancer; BMI; obesity; prognosis; radical cystectomy; survival; urothelial carcinoma

Indexed keywords

ADULT; AGE; AGED; ARTICLE; BODY MASS; CANCER GRADING; CANCER MORTALITY; CANCER PROGNOSIS; CANCER RECURRENCE; COHORT ANALYSIS; CYSTECTOMY; FEMALE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBESITY; PELVIS LYMPHADENECTOMY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TRANSITIONAL CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; BODY MASS INDEX; CARCINOMA, TRANSITIONAL CELL; CYSTECTOMY; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OBESITY; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; URINARY BLADDER NEOPLASMS;

EID: 84873111706     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2012.11322.x     Document Type: Article

References (26)

1. Wang Y, Beydoun MA,. The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic, and geographic characteristics: a systematic review and meta-regression analysis. Epidemiol Rev 2007; 29: 6-28
2. Mokdad AH, Bowman BA, Ford ES, Vinicor F, Marks JS, Koplan JP,. The continuing epidemics of obesity and diabetes in the United States. JAMA 2001; 286: 1195-1200
3. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ,. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003; 348: 1625-1638
4. Møller H, Mellemgaard A, Lindvig K, Olsen JH,. Obesity and cancer risk: a Danish record-linkage study. Eur J Cancer 1994; 30A: 344-350
5. Rapp K, Schroeder J, Klenk J, et al. Obesity and incidence of cancer: a large cohort study of over 145,000 adults in Austria. Br J Cancer 2005; 93: 1062-1067
6. Wolk A, Gridley G, Svensson M, et al. A prospective study of obesity and cancer risk (Sweden). Cancer Causes Control 2001; 12: 13-21
7. Lowrance WT, Thompson RH, Yee DS, Kaag M, Donat SM, Russo P,. Obesity is associated with a higher risk of clear-cell renal cell carcinoma than with other histologies. BJU Int 2010; 105: 16-20
8. Siegel EM, Ulrich CM, Poole EM, Holmes RS, Jacobsen PB, Shibata D,. The effects of obesity and obesity-related conditions on colorectal cancer prognosis. Cancer Control 2010; 17: 52-57
9. Freedland SJ, Sun L, Kane CJ, et al. Obesity and oncological outcome after radical prostatectomy: impact of prostate-specific antigen-based prostate cancer screening: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databases. BJU Int 2008; 102: 969-974
10. Dal Maso L, Zucchetto A, Talamini R, et al. Effect of obesity and other lifestyle factors on mortality in women with breast cancer. Int J Cancer 2008; 123: 2188-2194
11. Lee CT, Dunn RL, Chen BT, Joshi DP, Sheffield J, Montie JE,. Impact of body mass index on radical cystectomy. J Urol 2004; 172: 1281-1285
12. Chang SS, Jacobs B, Wells N, Smith JA, Cookson MS,. Increased body mass index predicts increased blood loss during radical cystectomy. J Urol 2004; 171: 1077-1079
13. Svatek RS, Fisher MB, Williams MB, et al. Age and body mass index are independent risk factors for the development of postoperative paralytic ileus after radical cystectomy. Urology 2010; 76: 1419-1424
14. Hafron J, Mitra N, Dalbagni G, Bochner B, Herr H, Donat SM,. Does body mass index affect survival of patients undergoing radical or partial cystectomy for bladder cancer? J Urol 2005; 173: 1513-1517
15. Novara G, Svatek RS, Karakiewicz PI, et al. Soft tissue surgical margin status is a powerful predictor of outcomes after radical cystectomy: a multicenter study of more than 4,400 patients. J Urol 2010; 183: 2165-2170
16. Shariat SF, Svatek RS, Tilki D, et al. International validation of the prognostic value of lymphovascular invasion in patients treated with radical cystectomy. BJU Int 2010; 105: 1402-1412
17. Maurer T, Maurer J, Retz M, et al. Influence of body mass index on operability, morbidity and disease outcome following radical cystectomy. Urol Int 2009; 82: 432-439
18. Suikkari AM, Koivisto VA, Rutanen EM, Yki-Järvinen H, Karonen SL, Seppälä M,. Insulin regulates the serum levels of low molecular weight insulin-like growth factor-binding protein. J Clin Endocrinol Metab 1988; 66: 266-272
19. Iwamura M, Ishibe M, Sluss PM, Cockett AT,. Characterization of insulin-like growth factor I binding sites in human bladder cancer cell lines. Urol Res 1993; 21: 27-32
20. Shariat SF, Kim J, Nguyen C, Wheeler TM, Lerner SP, Slawin KM,. Correlation of preoperative levels of IGF-I and IGFBP-3 with pathologic parameters and clinical outcome in patients with bladder cancer. Urology 2003; 61: 359-364
21. Hilmy M, Campbell R, Bartlett JM, McNicol AM, Underwood MA, McMillan DC,. The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic infiltration and COX-2 expression and survival in patients with transitional cell carcinoma of the urinary bladder. Br J Cancer 2006; 95: 1234-1238
22. Andrews B, Shariat SF, Kim JH, Wheeler TM, Slawin KM, Lerner SP,. Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer. J Urol 2002; 167: 1475-1481
23. Butt ZM, Perlmutter AE, Piacente PM, et al. Impact of body mass index on robot-assisted radical cystectomy. JSLS 2008; 12: 241-245
24. Herr HW,. Surgical factors in the treatment of superficial and invasive bladder cancer. Urol Clin North Am 2005; 32: 157-164
25. Kassouf W, Svatek RS, Shariat SF, et al. Critical analysis and validation of lymph node density as prognostic variable in urothelial carcinoma of bladder. Urol Oncol 2011; Epub ahead of print
26. Nielsen M, Palapattu G, Karakiewicz P, et al. A delay in radical cystectomy of >3 months is not associated with a worse clinical outcome. BJU Int 2007; 100: 1015-1020