메뉴 건너뛰기




Volumn 20, Issue 2, 2013, Pages 690-707

Comparative study of different exposure routes on the biotransformation and genotoxicity of PAHs in the flatfish species, Scophthalmus maximus

Author keywords

Biotransformation; DNA strand breaks; Marine fish; Mesocosm; Metabolites; Multi route exposure; PAHs

Indexed keywords

BACKGROUND LEVEL; BIOACCUMULATION; BIOMONITORING; BIOTRANSFORMATION; COMPARATIVE STUDY; CONCENTRATION (COMPOSITION); EXPERIMENTAL STUDY; FLATFISH; GENOTOXICITY; JUVENILE; MARINE ENVIRONMENT; MARINE POLLUTION; MESOCOSM; METABOLITE; PAH; POLLUTION EFFECT; POLLUTION EXPOSURE; SEDIMENT POLLUTION; TOXICITY TEST;

EID: 84873099407     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-012-1388-9     Document Type: Article
Times cited : (51)

References (78)
  • 1
    • 0033743951 scopus 로고    scopus 로고
    • PAH metabolites in bile, cytochrome P4501A and DNA adducts as environmental risk parameters for chronic oil exposure: a laboratory experiment with Atlantic cod
    • Aas E, Baussant T, Balk L, Liewenborg B, Andersen OK (2000) PAH metabolites in bile, cytochrome P4501A and DNA adducts as environmental risk parameters for chronic oil exposure: a laboratory experiment with Atlantic cod. Aquat Toxicol 51: 241-258.
    • (2000) Aquat Toxicol , vol.51 , pp. 241-258
    • Aas, E.1    Baussant, T.2    Balk, L.3    Liewenborg, B.4    Andersen, O.K.5
  • 3
    • 0037427846 scopus 로고    scopus 로고
    • Potential value of the comet assay and DNA adduct measurement in dab (Limanda limanda) for assessment of in situ exposure to genotoxic compounds
    • Akcha F, Vincent Hubert F, Pfhol-Leszkowicz A (2003) Potential value of the comet assay and DNA adduct measurement in dab (Limanda limanda) for assessment of in situ exposure to genotoxic compounds. Mutat Res Genet Toxicol Environ 534: 21-32.
    • (2003) Mutat Res Genet Toxicol Environ , vol.534 , pp. 21-32
    • Akcha, F.1    Vincent Hubert, F.2    Pfhol-Leszkowicz, A.3
  • 4
    • 3843146458 scopus 로고    scopus 로고
    • Measurement of DNA adducts and strand breaks in dab (Limanda limanda) collected in the field: effects of biotic (age, sex) and abiotic (sampling site and period) factors on the extent of DNA damage
    • Akcha F, Leday G, Pfohl-Leszkowicz A (2004) Measurement of DNA adducts and strand breaks in dab (Limanda limanda) collected in the field: effects of biotic (age, sex) and abiotic (sampling site and period) factors on the extent of DNA damage. Mutat Res Fundam Mol Mech 552: 197-207.
    • (2004) Mutat Res Fundam Mol Mech , vol.552 , pp. 197-207
    • Akcha, F.1    Leday, G.2    Pfohl-Leszkowicz, A.3
  • 5
    • 80053132750 scopus 로고    scopus 로고
    • A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis
    • Al-Subiai N, Moody AJ, Mustafa SA, Jha AN (2011) A multiple biomarker approach to investigate the effects of copper on the marine bivalve mollusc, Mytilus edulis. Ecotoxicol Environ Saf 74: 1913-1920.
    • (2011) Ecotoxicol Environ Saf , vol.74 , pp. 1913-1920
    • Al-Subiai, N.1    Moody, A.J.2    Mustafa, S.A.3    Jha, A.N.4
  • 6
    • 0025089630 scopus 로고
    • Bioconcentration: will water-borne organic chemicals accumulate in aquatic animals?
    • Barron MG (1990) Bioconcentration: will water-borne organic chemicals accumulate in aquatic animals? Environ Sci Technol 24: 1612-1618.
    • (1990) Environ Sci Technol , vol.24 , pp. 1612-1618
    • Barron, M.G.1
  • 8
    • 0034819558 scopus 로고    scopus 로고
    • Ethoxyresorufin-O-deethylase induction in trout exposed to mixtures of polycyclic aromatic hydrocarbons
    • Basu N, Billiard S, Fragoso N, Omoike A, Tabash S, Brown S, Hodson P (2001) Ethoxyresorufin-O-deethylase induction in trout exposed to mixtures of polycyclic aromatic hydrocarbons. Environ Toxicol Chem 20: 1244-1251.
    • (2001) Environ Toxicol Chem , vol.20 , pp. 1244-1251
    • Basu, N.1    Billiard, S.2    Fragoso, N.3    Omoike, A.4    Tabash, S.5    Brown, S.6    Hodson, P.7
  • 9
    • 57249109828 scopus 로고    scopus 로고
    • Internal standard quantification method and gas chromatograph-mass spectrometer (GC-MS): a reliable tool for polycyclic aromatic hydrocarbon (PAH) quantification in natural matrices
    • Baumard P, Budzinski H (1997) Internal standard quantification method and gas chromatograph-mass spectrometer (GC-MS): a reliable tool for polycyclic aromatic hydrocarbon (PAH) quantification in natural matrices. Analusis 25: 246-252.
    • (1997) Analusis , vol.25 , pp. 246-252
    • Baumard, P.1    Budzinski, H.2
  • 10
    • 0034832952 scopus 로고    scopus 로고
    • Bioaccumulation of polycyclic aromatic compounds: 1. Bioconcentration in two marine species and in semipermeable membrane devices during chronic exposure to dispersed crude oil
    • Baussant T, Sanni S, Jonsson G, Skadsheim A, Børseth JF (2001) Bioaccumulation of polycyclic aromatic compounds: 1. Bioconcentration in two marine species and in semipermeable membrane devices during chronic exposure to dispersed crude oil. Environ Toxicol Chem 20: 1175-1184.
    • (2001) Environ Toxicol Chem , vol.20 , pp. 1175-1184
    • Baussant, T.1    Sanni, S.2    Jonsson, G.3    Skadsheim, A.4    Børseth, J.F.5
  • 11
    • 77952936552 scopus 로고    scopus 로고
    • Effects of exposure to Prestige-like heavy fuel oil and to perfluorooctane sulfonate on conventional biomarkers and target gene transcription in the thicklip grey mullet Chelon labrosus
    • Bilbao E, Raingeard D, Diaz de Cerio O, Ortiz-Zarragoitia M, Ruiz P, Izagirre U, Orbea A, Marigomez I, Cajaraville M, Cancio I (2010) Effects of exposure to Prestige-like heavy fuel oil and to perfluorooctane sulfonate on conventional biomarkers and target gene transcription in the thicklip grey mullet Chelon labrosus. Aquat Toxicol 98: 282-296.
    • (2010) Aquat Toxicol , vol.98 , pp. 282-296
    • Bilbao, E.1    Raingeard, D.2    Diaz de Cerio, O.3    Ortiz-Zarragoitia, M.4    Ruiz, P.5    Izagirre, U.6    Orbea, A.7    Marigomez, I.8    Cajaraville, M.9    Cancio, I.10
  • 14
    • 0031440972 scopus 로고    scopus 로고
    • Evaluation of sediment contamination by polycyclic aromatic hydrocarbons in the Gironde estuary
    • Budzinski H, Jones I, Bellocq J, Piérard C, Garrigues P (1997) Evaluation of sediment contamination by polycyclic aromatic hydrocarbons in the Gironde estuary. Mar Chem 58: 85-97.
    • (1997) Mar Chem , vol.58 , pp. 85-97
    • Budzinski, H.1    Jones, I.2    Bellocq, J.3    Piérard, C.4    Garrigues, P.5
  • 15
    • 0032943792 scopus 로고    scopus 로고
    • Optimisation of the microwave-assisted extraction in open cell of polycyclic aromatic hydrocarbons from soils and sediments. Study of moisture effect
    • Budzinski H, Letellier M, Garrigues P, Le Ménach K (1999) Optimisation of the microwave-assisted extraction in open cell of polycyclic aromatic hydrocarbons from soils and sediments. Study of moisture effect. J Chromatogr A 837: 187-200.
    • (1999) J Chromatogr A , vol.837 , pp. 187-200
    • Budzinski, H.1    Letellier, M.2    Garrigues, P.3    Le Ménach, K.4
  • 16
  • 18
    • 0032123512 scopus 로고    scopus 로고
    • Ethoxyresorufin-O-deethylase activity and fixed wavelength fluorescence detection of PAHs metabolites in bile in turbot (Scophthalmus maximus L.) exposed to a dispersed topped crude oil in a continuous flow system
    • Camus L, Aas E, Borseth JF (1998) Ethoxyresorufin-O-deethylase activity and fixed wavelength fluorescence detection of PAHs metabolites in bile in turbot (Scophthalmus maximus L.) exposed to a dispersed topped crude oil in a continuous flow system. Mar Environ Res 46: 29-32.
    • (1998) Mar Environ Res , vol.46 , pp. 29-32
    • Camus, L.1    Aas, E.2    Borseth, J.F.3
  • 19
    • 0025854661 scopus 로고
    • Hepatic activities of xenobiotic metabolizing enzymes and biliary levels of xenobiotics in English sole (Parophrys vetulus) exposed to environmental contaminants
    • Collier TK, Varanasi U (1991) Hepatic activities of xenobiotic metabolizing enzymes and biliary levels of xenobiotics in English sole (Parophrys vetulus) exposed to environmental contaminants. Arch Environ Contam Toxicol 20: 462-473.
    • (1991) Arch Environ Contam Toxicol , vol.20 , pp. 462-473
    • Collier, T.K.1    Varanasi, U.2
  • 22
    • 33847630719 scopus 로고    scopus 로고
    • Co-ordination of DNA single strand break repair
    • Dianov GL, Parsons JL (2007) Co-ordination of DNA single strand break repair. DNA Repair 6: 454-460.
    • (2007) DNA Repair , vol.6 , pp. 454-460
    • Dianov, G.L.1    Parsons, J.L.2
  • 23
    • 0001992708 scopus 로고
    • Examination of diols and diol epoxides of polycyclic aromatic hydrocarbons as substrates for rat liver dihydrodiol dehydrogenase
    • Flowers-Geary L, Harvey RG, Penning TM (1992) Examination of diols and diol epoxides of polycyclic aromatic hydrocarbons as substrates for rat liver dihydrodiol dehydrogenase. Biochem J 11: 49-58.
    • (1992) Biochem J , vol.11 , pp. 49-58
    • Flowers-Geary, L.1    Harvey, R.G.2    Penning, T.M.3
  • 24
    • 62149138337 scopus 로고    scopus 로고
    • The Comet assay for the evaluation of genotoxic impact in aquatic environments
    • Frenzilli G, Nigro M, Lyons BP (2009) The Comet assay for the evaluation of genotoxic impact in aquatic environments. Mutat Res Rev Mutat 681: 80-92.
    • (2009) Mutat Res Rev Mutat , vol.681 , pp. 80-92
    • Frenzilli, G.1    Nigro, M.2    Lyons, B.P.3
  • 26
    • 0019074870 scopus 로고
    • Benzo[a]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes
    • Gelboin HV (1980) Benzo[a]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes. Physiol Rev 60: 1107-1166.
    • (1980) Physiol Rev , vol.60 , pp. 1107-1166
    • Gelboin, H.V.1
  • 27
    • 0004141204 scopus 로고
    • GESAMP (IMO/FAO/UNESCO/WMO/IAEA/UN/UNEP Joint Group of Experts on the Scientific Aspects of Marine Pollution), Reports and Studies No 50. London
    • GESAMP (IMO/FAO/UNESCO/WMO/IAEA/UN/UNEP Joint Group of Experts on the Scientific Aspects of Marine Pollution) (1993) Impact of oil and related chemicals and wastes on the marine environment. Reports and Studies No 50. London, p 180.
    • (1993) Impact of Oil and Related Chemicals and Wastes On the Marine Environment , pp. 180
  • 28
    • 48349097982 scopus 로고    scopus 로고
    • Flow cytometry for the evaluation of chromosomal damage in turbot Psetta maxima (L.) exposed to the dissolved fraction of heavy fuel oil in sea water: a comparison with classical biomarkers
    • Goanvec C, Theron M, Lacoue-Labarthe T, Poirier E, Guyomarch J, Le-Floch S, Laroche J, Nonnotte L, Nonnotte G (2008) Flow cytometry for the evaluation of chromosomal damage in turbot Psetta maxima (L.) exposed to the dissolved fraction of heavy fuel oil in sea water: a comparison with classical biomarkers. J Fish Biol 73: 395-413.
    • (2008) J Fish Biol , vol.73 , pp. 395-413
    • Goanvec, C.1    Theron, M.2    Lacoue-Labarthe, T.3    Poirier, E.4    Guyomarch, J.5    Le-Floch, S.6    Laroche, J.7    Nonnotte, L.8    Nonnotte, G.9
  • 29
    • 34249733149 scopus 로고    scopus 로고
    • Assessment of the Mediterranean sediments contamination by persistent organic pollutants
    • Gómez-Gutiérrez A, Garnacho E, Bayona JM, Albaigés J (2007) Assessment of the Mediterranean sediments contamination by persistent organic pollutants. Environ Pollut 148: 396-408.
    • (2007) Environ Pollut , vol.148 , pp. 396-408
    • Gómez-Gutiérrez, A.1    Garnacho, E.2    Bayona, J.M.3    Albaigés, J.4
  • 32
    • 33746863286 scopus 로고    scopus 로고
    • Analysis of CYP4501A1, PAHs metabolites in bile, and genotoxic damage in Oncorhynchus mykiss exposed to Biobío River sediments, Central Chile
    • Inzunza B, Orrego R, Penalosa M, Gavilan JF, Barra R (2006) Analysis of CYP4501A1, PAHs metabolites in bile, and genotoxic damage in Oncorhynchus mykiss exposed to Biobío River sediments, Central Chile. Ecotoxicol Environ Saf 65: 242-251.
    • (2006) Ecotoxicol Environ Saf , vol.65 , pp. 242-251
    • Inzunza, B.1    Orrego, R.2    Penalosa, M.3    Gavilan, J.F.4    Barra, R.5
  • 33
    • 31244436671 scopus 로고    scopus 로고
    • Bioconcentration, biotransformation, and elimination of polycyclic aromatic hydrocarbons in sheepshead minnows (Cyprinodon variegatus) exposed to contaminated seawater
    • Jonsson G, Bechmann R, Bamber SD, Baussant T (2004) Bioconcentration, biotransformation, and elimination of polycyclic aromatic hydrocarbons in sheepshead minnows (Cyprinodon variegatus) exposed to contaminated seawater. Environ Toxicol Chem 23: 1538-1548.
    • (2004) Environ Toxicol Chem , vol.23 , pp. 1538-1548
    • Jonsson, G.1    Bechmann, R.2    Bamber, S.D.3    Baussant, T.4
  • 34
    • 34147144537 scopus 로고    scopus 로고
    • PAH metabolites in bile fluids of dab (Limanda limanda) and flounder (Platichthys flesus): spatial distribution and seasonal changes
    • Kamman U (2007) PAH metabolites in bile fluids of dab (Limanda limanda) and flounder (Platichthys flesus): spatial distribution and seasonal changes. Environ Sci Pollut Res 14: 102-108.
    • (2007) Environ Sci Pollut Res , vol.14 , pp. 102-108
    • Kamman, U.1
  • 36
    • 84856023526 scopus 로고    scopus 로고
    • Growth and condition indices of juvenile turbot, Scophthalmus maximus, exposed to contaminated sediments: effects of metallic and organic compounds
    • Kerambrun E, Henry F, Perrichon P, Courcot L, Meziane T, Spilmont N, Amara R (2012) Growth and condition indices of juvenile turbot, Scophthalmus maximus, exposed to contaminated sediments: effects of metallic and organic compounds. Aquat Toxicol 108: 130-140.
    • (2012) Aquat Toxicol , vol.108 , pp. 130-140
    • Kerambrun, E.1    Henry, F.2    Perrichon, P.3    Courcot, L.4    Meziane, T.5    Spilmont, N.6    Amara, R.7
  • 37
    • 3342963570 scopus 로고    scopus 로고
    • Genotoxicity of field-collected inter-tidal sediments from Cork Harbor, Ireland, to juvenile turbot (Scophthalmus maximus L.) as measured by the comet assay
    • Kilemade MF, Hartl MGJ, Sheehan D, Mothersill C, van Pelt FNAM, O'Halloran J, O'Brien NM (2004) Genotoxicity of field-collected inter-tidal sediments from Cork Harbor, Ireland, to juvenile turbot (Scophthalmus maximus L.) as measured by the comet assay. Environ Mol Mutagen 44: 56-64.
    • (2004) Environ Mol Mutagen , vol.44 , pp. 56-64
    • Kilemade, M.F.1    Hartl, M.G.J.2    Sheehan, D.3    Mothersill, C.4    van Pelt, F.N.A.M.5    O'Halloran, J.6    O'Brien, N.M.7
  • 38
    • 59149103618 scopus 로고    scopus 로고
    • Effects of contaminated sediment from Cork Harbour, Ireland on the cytochrome P450 system of turbot
    • Kilemade M, Hartl MGJ, O'Halloran J, O'Brien NM, Sheelan D (2009) Effects of contaminated sediment from Cork Harbour, Ireland on the cytochrome P450 system of turbot. Ecotoxicol Environ Saf 72: 747-755.
    • (2009) Ecotoxicol Environ Saf , vol.72 , pp. 747-755
    • Kilemade, M.1    Hartl, M.G.J.2    O'Halloran, J.3    O'Brien, N.M.4    Sheelan, D.5
  • 39
    • 33847218646 scopus 로고    scopus 로고
    • Ethoxyresorufin-O-deethylase (EROD) and vitellogenin (VTG) in flounder (Platichthys flesus): system interaction, crosstalk and implications for monitoring
    • Kirby MF, Smith AJ, Rooke J, Neall P, Scott AP, Katsiadaki I (2007) Ethoxyresorufin-O-deethylase (EROD) and vitellogenin (VTG) in flounder (Platichthys flesus): system interaction, crosstalk and implications for monitoring. Aquat Toxicol 81: 233-244.
    • (2007) Aquat Toxicol , vol.81 , pp. 233-244
    • Kirby, M.F.1    Smith, A.J.2    Rooke, J.3    Neall, P.4    Scott, A.P.5    Katsiadaki, I.6
  • 40
    • 0021128839 scopus 로고
    • Determination of metabolites of xenobiotics in the bile of fish from polluted waterways
    • Krahn MM, Myers MS, Burrows DG, Malins DC (1984) Determination of metabolites of xenobiotics in the bile of fish from polluted waterways. Xenobiotica 14: 633-646.
    • (1984) Xenobiotica , vol.14 , pp. 633-646
    • Krahn, M.M.1    Myers, M.S.2    Burrows, D.G.3    Malins, D.C.4
  • 41
    • 0022657397 scopus 로고
    • Associations between metabolites of aromatic compounds in bile and the occurrence of hepatic lesions in English sole (Parophrys vetulus) from Puget Sound, Washington
    • Krahn MM, Rhodes LD, Myers MS, Moore LK, MacLeod WD, Malins DC (1986) Associations between metabolites of aromatic compounds in bile and the occurrence of hepatic lesions in English sole (Parophrys vetulus) from Puget Sound, Washington. Arch Environ Contam Toxicol 15: 61-67.
    • (1986) Arch Environ Contam Toxicol , vol.15 , pp. 61-67
    • Krahn, M.M.1    Rhodes, L.D.2    Myers, M.S.3    Moore, L.K.4    MacLeod, W.D.5    Malins, D.C.6
  • 42
    • 77956132651 scopus 로고    scopus 로고
    • Responses of metabolic pathways to polycyclic aromatic compounds in flounder following oil spill in the Baltic Sea near the Estonian coast
    • Kreitsberg R, Zemit I, Freiberg R, Tambets M, Tuvikene A (2010) Responses of metabolic pathways to polycyclic aromatic compounds in flounder following oil spill in the Baltic Sea near the Estonian coast. Aquat Toxicol 99: 473-478.
    • (2010) Aquat Toxicol , vol.99 , pp. 473-478
    • Kreitsberg, R.1    Zemit, I.2    Freiberg, R.3    Tambets, M.4    Tuvikene, A.5
  • 44
    • 0032543425 scopus 로고    scopus 로고
    • Antimutagenic role of base-excision repair enzymes upon free radical- induced DNA damage
    • Laval J, Jurado J, Saparbaev M, Sidorkina O (1998) Antimutagenic role of base-excision repair enzymes upon free radical- induced DNA damage. Mutat Res 402: 93-102.
    • (1998) Mutat Res , vol.402 , pp. 93-102
    • Laval, J.1    Jurado, J.2    Saparbaev, M.3    Sidorkina, O.4
  • 45
    • 77955375894 scopus 로고    scopus 로고
    • Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats
    • Marie-Desvergne C, Maître A, Bouchard M, Ravanat JL, Viau C (2010) Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats. Chem Res Toxicol 23: 1207-1214.
    • (2010) Chem Res Toxicol , vol.23 , pp. 1207-1214
    • Marie-Desvergne, C.1    Maître, A.2    Bouchard, M.3    Ravanat, J.L.4    Viau, C.5
  • 46
    • 0036229745 scopus 로고    scopus 로고
    • Improved accuracy of GC-MS quantification of aliphatic and aromatic hydrocarbons in marine sediments and petroleums. Validation on reference matrices and application to the Erika oil spill
    • Mazeas L, Budzinski H (2002) Improved accuracy of GC-MS quantification of aliphatic and aromatic hydrocarbons in marine sediments and petroleums. Validation on reference matrices and application to the Erika oil spill. Int J Environ Anal Chem 82: 157-173.
    • (2002) Int J Environ Anal Chem , vol.82 , pp. 157-173
    • Mazeas, L.1    Budzinski, H.2
  • 47
    • 27744602881 scopus 로고    scopus 로고
    • Solid-phase extraction and purification for the quantification of polycyclic aromatic hydrocarbon metabolites in fish bile
    • Mazéas O, Budzinski H (2005) Solid-phase extraction and purification for the quantification of polycyclic aromatic hydrocarbon metabolites in fish bile. Anal Bioanal Chem 383: 985-990.
    • (2005) Anal Bioanal Chem , vol.383 , pp. 985-990
    • Mazéas, O.1    Budzinski, H.2
  • 50
  • 52
    • 0028944320 scopus 로고
    • Comparative metabolism of benzo(a)pyrene, chrysene and phenanthrene by brown bullhead liver microsomes
    • Pangrekar J, Kandaswami C, Kole P, Kumar S, Sikka HC (1995) Comparative metabolism of benzo(a)pyrene, chrysene and phenanthrene by brown bullhead liver microsomes. Mar Environ Res 39: 51-55.
    • (1995) Mar Environ Res , vol.39 , pp. 51-55
    • Pangrekar, J.1    Kandaswami, C.2    Kole, P.3    Kumar, S.4    Sikka, H.C.5
  • 53
    • 0030999502 scopus 로고    scopus 로고
    • Responses of hepatic cytochrome P450 1A and formation of DNA-adducts in juveniles of turbot (Scophthalmus maximus L.) exposed to water-borne benzo[a]pyrene
    • Peters LD, Morse HR, Waters R, Livingstone DR (1997) Responses of hepatic cytochrome P450 1A and formation of DNA-adducts in juveniles of turbot (Scophthalmus maximus L.) exposed to water-borne benzo[a]pyrene. Aquat Toxicol 38: 67-82.
    • (1997) Aquat Toxicol , vol.38 , pp. 67-82
    • Peters, L.D.1    Morse, H.R.2    Waters, R.3    Livingstone, D.R.4
  • 54
    • 0037789602 scopus 로고    scopus 로고
    • Comparison of biomarker and pathological responses in flounder (Platichthys flesus L.) induced by ingested polycyclic aromatic hydrocarbon (PAH) contamination
    • Reynolds WJ, Feist SW, Jones GJ, Lyons BP, Sheahan DA, Stentiford GD (2003) Comparison of biomarker and pathological responses in flounder (Platichthys flesus L.) induced by ingested polycyclic aromatic hydrocarbon (PAH) contamination. Chemosphere 52: 1135-1145.
    • (2003) Chemosphere , vol.52 , pp. 1135-1145
    • Reynolds, W.J.1    Feist, S.W.2    Jones, G.J.3    Lyons, B.P.4    Sheahan, D.A.5    Stentiford, G.D.6
  • 55
    • 0037213735 scopus 로고    scopus 로고
    • Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries
    • Ruddock PJ, Bird DJ, McEvoy J, Peters LD (2003) Bile metabolites of polycyclic aromatic hydrocarbons (PAHs) in European eels Anguilla anguilla from United Kingdom estuaries. Sci Total Environ 301: 105-117.
    • (2003) Sci Total Environ , vol.301 , pp. 105-117
    • Ruddock, P.J.1    Bird, D.J.2    McEvoy, J.3    Peters, L.D.4
  • 56
    • 84859948590 scopus 로고    scopus 로고
    • Responses of conventional and molecular biomarkers in turbot Scophthalmus maximus exposed to heavy fuel oil no. 6 and styrene
    • Ruiz P, Ortiz-Zarragoita M, Orbea A, Theron M, Le Floch S, Cajaraville M (2012) Responses of conventional and molecular biomarkers in turbot Scophthalmus maximus exposed to heavy fuel oil no. 6 and styrene. Aquat Toxicol 116-117: 116-128.
    • (2012) Aquat Toxicol , vol.116-117 , pp. 116-128
    • Ruiz, P.1    Ortiz-Zarragoita, M.2    Orbea, A.3    Theron, M.4    Le Floch, S.5    Cajaraville, M.6
  • 57
    • 77957231928 scopus 로고    scopus 로고
    • Validating a multi-biomarker approach with the shanny Lipophrys pholis to monitor oil spills in European marine ecosystems
    • Santos MM, Solé M, Lima D, Hambach B, Ferreira AM, Reis-Henriques MA (2010) Validating a multi-biomarker approach with the shanny Lipophrys pholis to monitor oil spills in European marine ecosystems. Chemosphere 81: 685-691.
    • (2010) Chemosphere , vol.81 , pp. 685-691
    • Santos, M.M.1    Solé, M.2    Lima, D.3    Hambach, B.4    Ferreira, A.M.5    Reis-Henriques, M.A.6
  • 58
    • 0000462256 scopus 로고    scopus 로고
    • Chemical sampling and analysis of petroleum hydrocarbons in near-surface seawater of Prince William Sound after the Exxon Valdez oil spill
    • Short JW, Harris PM (1996) Chemical sampling and analysis of petroleum hydrocarbons in near-surface seawater of Prince William Sound after the Exxon Valdez oil spill. Am Fish Soc Symp 18: 17-28.
    • (1996) Am Fish Soc Symp , vol.18 , pp. 17-28
    • Short, J.W.1    Harris, P.M.2
  • 60
    • 0028865604 scopus 로고
    • The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay)
    • Speit G, Hartmann A (1995) The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay). Mutagenesis 10: 555-559.
    • (1995) Mutagenesis , vol.10 , pp. 555-559
    • Speit, G.1    Hartmann, A.2
  • 61
    • 0030442358 scopus 로고    scopus 로고
    • Hydrocarbon concentrations in the northern North Sea and effects on fish larvae
    • Stagg RM, McIntosh A (1996) Hydrocarbon concentrations in the northern North Sea and effects on fish larvae. Sci Total Environ 186: 189-201.
    • (1996) Sci Total Environ , vol.186 , pp. 189-201
    • Stagg, R.M.1    McIntosh, A.2
  • 62
    • 84857040476 scopus 로고    scopus 로고
    • PAH biomarkers in common eelpout (Zoarces viviparus) from Danish waters
    • Tairova ZM, Strand J, Chevalier J, Andersen O (2012) PAH biomarkers in common eelpout (Zoarces viviparus) from Danish waters. Mar Environ Res 75: 45-53.
    • (2012) Mar Environ Res , vol.75 , pp. 45-53
    • Tairova, Z.M.1    Strand, J.2    Chevalier, J.3    Andersen, O.4
  • 63
    • 79954596319 scopus 로고    scopus 로고
    • Hepatic biotransformation genes and enzymes and PAH metabolites in bile of common sole (Solea solea, Linnaeus, 1758) from an oil-contaminated site in the Mediterranean Sea: a field study
    • Trisciani A, Corsi I, Torre CD, Perra G, Focardi S (2011) Hepatic biotransformation genes and enzymes and PAH metabolites in bile of common sole (Solea solea, Linnaeus, 1758) from an oil-contaminated site in the Mediterranean Sea: a field study. Mar Pollut Bull 62: 806-814.
    • (2011) Mar Pollut Bull , vol.62 , pp. 806-814
    • Trisciani, A.1    Corsi, I.2    Torre, C.D.3    Perra, G.4    Focardi, S.5
  • 65
    • 50449106424 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons in surface seawater and in indigenous mussels (Mytilus galloprovincialis) from coastal areas of the Saronikos Gulf (Greece)
    • Valavanidis A, Vlachogianni T, Triantafillaki S, Dassenakis M, Androutsos F, Scoullos M (2008) Polycyclic aromatic hydrocarbons in surface seawater and in indigenous mussels (Mytilus galloprovincialis) from coastal areas of the Saronikos Gulf (Greece). Estuar Coast Shelf Sci 79: 733-739.
    • (2008) Estuar Coast Shelf Sci , vol.79 , pp. 733-739
    • Valavanidis, A.1    Vlachogianni, T.2    Triantafillaki, S.3    Dassenakis, M.4    Androutsos, F.5    Scoullos, M.6
  • 66
    • 0037290663 scopus 로고    scopus 로고
    • Fish bioaccumulation and biomarkers in environmental risk assessment: a review
    • van der Oost R, Beyer J, Vermeulen NPE (2003) Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environ Toxicol Pharmacol 13: 57-149.
    • (2003) Environ Toxicol Pharmacol , vol.13 , pp. 57-149
    • van der Oost, R.1    Beyer, J.2    Vermeulen, N.P.E.3
  • 67
    • 0035977896 scopus 로고    scopus 로고
    • The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis
    • van Steeg H (2001) The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis. Toxicol Lett 120: 209-219.
    • (2001) Toxicol Lett , vol.120 , pp. 209-219
    • van Steeg, H.1
  • 68
    • 0019870572 scopus 로고
    • 14C]-naphthalene in oil-contaminated sediment
    • 14C]-naphthalene in oil-contaminated sediment. Aquat Toxicol 1: 49-67.
    • (1981) Aquat Toxicol , vol.1 , pp. 49-67
    • Varanasi, U.1    Gmur, D.J.2
  • 69
    • 0025828389 scopus 로고
    • Disposition of xenobiotic chemicals and metabolites in marine organisms
    • Varanasi U, Stein JE (1991) Disposition of xenobiotic chemicals and metabolites in marine organisms. Environ Health Perspect 90: 93-100.
    • (1991) Environ Health Perspect , vol.90 , pp. 93-100
    • Varanasi, U.1    Stein, J.E.2
  • 70
    • 0022470467 scopus 로고
    • Comparative metabolism of benzo(a)pyrene and covalent binding to hepatic DNA in English sole, starry flounder, and rat
    • Varanasi U, Nishimoto M, Reichert WL, Eberhart BTL (1986) Comparative metabolism of benzo(a)pyrene and covalent binding to hepatic DNA in English sole, starry flounder, and rat. Cancer Res 46: 3817-3824.
    • (1986) Cancer Res , vol.46 , pp. 3817-3824
    • Varanasi, U.1    Nishimoto, M.2    Reichert, W.L.3    Eberhart, B.T.L.4
  • 71
    • 0024508507 scopus 로고
    • Formation and persistence of benzo[a]pyrene-diolepoxide-DNA adducts in liver of English sole (Parophrys vetulus)
    • Varanasi U, Reichert WL, Eberhart BTL, Stein JE (1989) Formation and persistence of benzo[a]pyrene-diolepoxide-DNA adducts in liver of English sole (Parophrys vetulus). Chem Biol Interact 69: 203-216.
    • (1989) Chem Biol Interact , vol.69 , pp. 203-216
    • Varanasi, U.1    Reichert, W.L.2    Eberhart, B.T.L.3    Stein, J.E.4
  • 73
    • 14644410449 scopus 로고    scopus 로고
    • Molecular and isotopic identification of PAH sources in a highly industrialized urban estuary
    • Walker SE, Dickhut RM, Chisholm-Brause C, Sylva S, Reddy CM (2005) Molecular and isotopic identification of PAH sources in a highly industrialized urban estuary. Org Geochem 36: 619-632.
    • (2005) Org Geochem , vol.36 , pp. 619-632
    • Walker, S.E.1    Dickhut, R.M.2    Chisholm-Brause, C.3    Sylva, S.4    Reddy, C.M.5
  • 74
    • 0025636297 scopus 로고
    • Evaluation of the carcinogenic potency of 4 environmental polycyclic aromatic compounds following intrapulmonary application in rats
    • Wenzel-Hartung R, Brune H, Grimmer G, Germann P, Timm J, Wosniok W (1990) Evaluation of the carcinogenic potency of 4 environmental polycyclic aromatic compounds following intrapulmonary application in rats. Exp Pathol 40: 221-227.
    • (1990) Exp Pathol , vol.40 , pp. 221-227
    • Wenzel-Hartung, R.1    Brune, H.2    Grimmer, G.3    Germann, P.4    Timm, J.5    Wosniok, W.6
  • 76
    • 0033883046 scopus 로고    scopus 로고
    • Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure
    • Whyte JJ, Jung RE, Schmitt CJ, Tillitt DE (2000) Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure. Crit Rev Toxicol 30: 347-570.
    • (2000) Crit Rev Toxicol , vol.30 , pp. 347-570
    • Whyte, J.J.1    Jung, R.E.2    Schmitt, C.J.3    Tillitt, D.E.4
  • 77
    • 33751325323 scopus 로고    scopus 로고
    • Comet assay for the detection of genotoxicity in blood cells of flounder (Paralichthys olivaceus) exposed to sediments and polycyclic aromatic hydrocarbons
    • Woo S, Kim S, Yum S, Yim UH, Lee TK (2006) Comet assay for the detection of genotoxicity in blood cells of flounder (Paralichthys olivaceus) exposed to sediments and polycyclic aromatic hydrocarbons. Mar Poll Bull 52: 1768-1775.
    • (2006) Mar Poll Bull , vol.52 , pp. 1768-1775
    • Woo, S.1    Kim, S.2    Yum, S.3    Yim, U.H.4    Lee, T.K.5
  • 78
    • 20444412643 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review
    • Xue W, Warshawsky D (2005) Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review. Toxicol Appl Pharmacol 206: 73-93.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 73-93
    • Xue, W.1    Warshawsky, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.